Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7373-01A-11R-2016-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

430 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7373-01A-11R-2016-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAED1 AhpC/TSA antioxidant enzyme domain containing 1
ABHD12B abhydrolase domain containing 12B
ACSL4 acyl-CoA synthetase long-chain family member 4
ADAR adenosine deaminase, RNA-specific
ADPRHL2 ADP-ribosylhydrolase like 2
ADRB2 adrenoceptor beta 2, surface
AEN apoptosis enhancing nuclease
AFF4 AF4/FMR2 family, member 4
AHCYL2 adenosylhomocysteinase-like 2
AKIRIN1 akirin 1
ALKBH8 alkB, alkylation repair homolog 8 (E. coli)
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD13C ankyrin repeat domain 13C
ANXA3 annexin A3
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APLN apelin
AQP6 aquaporin 6, kidney specific
ARHGAP29 Rho GTPase activating protein 29
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ASIC2 acid sensing (proton gated) ion channel 2
ATF1 activating transcription factor 1
AXL AXL receptor tyrosine kinase
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BATF2 basic leucine zipper transcription factor, ATF-like 2
BCAR1 breast cancer anti-estrogen resistance 1
BCAR3 breast cancer anti-estrogen resistance 3
BCL9L B-cell CLL/lymphoma 9-like
BNC1 basonuclin 1
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C12ORF43 chromosome 12 open reading frame 43
C1ORF109 chromosome 1 open reading frame 109
C1ORF52 chromosome 1 open reading frame 52
C1S complement component 1, s subcomponent
C20ORF141 chromosome 20 open reading frame 141
C20ORF173 chromosome 20 open reading frame 173
C9ORF41 chromosome 9 open reading frame 41
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CC2D1B coiled-coil and C2 domain containing 1B
CCBE1 collagen and calcium binding EGF domains 1
CCL24 chemokine (C-C motif) ligand 24
CCNJL cyclin J-like
CCR8 chemokine (C-C motif) receptor 8
CCSAP centriole, cilia and spindle-associated protein
CD209 CD209 molecule
CD300E CD300e molecule
CD86 CD86 molecule
CDC25A cell division cycle 25A
CDC27 cell division cycle 27
CDCA8 cell division cycle associated 8
CDCP1 CUB domain containing protein 1
CDH13 cadherin 13
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CEP170P1 centrosomal protein 170kDa pseudogene 1
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CHD1 chromodomain helicase DNA binding protein 1
CHEK1 checkpoint kinase 1
CKAP2 cytoskeleton associated protein 2
CKAP2L cytoskeleton associated protein 2-like
CKAP5 cytoskeleton associated protein 5
CLMP CXADR-like membrane protein
CLSPN claspin
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COA7 cytochrome c oxidase assembly factor 7 (putative)
COL16A1 collagen, type XVI, alpha 1
COL4A6 collagen, type IV, alpha 6
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CTPS1 CTP synthase 1
CWF19L2 CWF19-like 2, cell cycle control (S. pombe)
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DAAM1 dishevelled associated activator of morphogenesis 1
DCLRE1B DNA cross-link repair 1B
DCP1A decapping mRNA 1A
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
DENND5B DENN/MADD domain containing 5B
DEPDC7 DEP domain containing 7
DFNA5 deafness, autosomal dominant 5
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37
DIAPH1 diaphanous-related formin 1
DIAPH3 diaphanous-related formin 3
DLL1 delta-like 1 (Drosophila)
DLX4 distal-less homeobox 4
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNER delta/notch-like EGF repeat containing
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
DOCK7 dedicator of cytokinesis 7
DPYD dihydropyrimidine dehydrogenase
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
DRAM1 DNA-damage regulated autophagy modulator 1
DSCAM Down syndrome cell adhesion molecule
DSE dermatan sulfate epimerase
DUSP7 dual specificity phosphatase 7
E2F4 E2F transcription factor 4, p107/p130-binding
EBNA1BP2 EBNA1 binding protein 2
EFTUD1 elongation factor Tu GTP binding domain containing 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ELF4 E74-like factor 4 (ets domain transcription factor)
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EPS15 epidermal growth factor receptor pathway substrate 15
EPSTI1 epithelial stromal interaction 1 (breast)
ERAP1 endoplasmic reticulum aminopeptidase 1
ERP44 endoplasmic reticulum protein 44
ESYT1 extended synaptotagmin-like protein 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EXO5 exonuclease 5
F3 coagulation factor III (thromboplastin, tissue factor)
FAM106CP family with sequence similarity 106, member C, pseudogene
FAM169A family with sequence similarity 169, member A
FAM65A family with sequence similarity 65, member A
FAM69A family with sequence similarity 69, member A
FAT1 FAT atypical cadherin 1
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FER fer (fps/fes related) tyrosine kinase
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGD6 FYVE, RhoGEF and PH domain containing 6
FGL1 fibrinogen-like 1
FKBP15 FK506 binding protein 15, 133kDa
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FMNL2 formin-like 2
FNDC3A fibronectin type III domain containing 3A
FOXJ3 forkhead box J3
FOXN2 forkhead box N2
FST follistatin
FSTL3 follistatin-like 3 (secreted glycoprotein)
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli)
GANC glucosidase, alpha; neutral C
GBP1 guanylate binding protein 1, interferon-inducible
GBP3 guanylate binding protein 3
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GJB3 gap junction protein, beta 3, 31kDa
GJB5 gap junction protein, beta 5, 31.1kDa
GJD3 gap junction protein, delta 3, 31.9kDa
GLB1 galactosidase, beta 1
GLB1L3 galactosidase, beta 1-like 3
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNG5 guanine nucleotide binding protein (G protein), gamma 5
GOLM1 golgi membrane protein 1
GPR50 G protein-coupled receptor 50
GPSM2 G-protein signaling modulator 2
HCG9 HLA complex group 9 (non-protein coding)
HDAC7 histone deacetylase 7
HEATR1 HEAT repeat containing 1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIAT1 hippocampus abundant transcript 1
HNRNPK heterogeneous nuclear ribonucleoprotein K
HRCT1 histidine rich carboxyl terminus 1
HRH1 histamine receptor H1
HS6ST2 heparan sulfate 6-O-sulfotransferase 2
HYI hydroxypyruvate isomerase (putative)
ICOS inducible T-cell co-stimulator
IFI44 interferon-induced protein 44
IFIH1 interferon induced with helicase C domain 1
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFITM1 interferon induced transmembrane protein 1
IFITM3 interferon induced transmembrane protein 3
IGFBP1 insulin-like growth factor binding protein 1
IGSF21 immunoglobin superfamily, member 21
IL12RB1 interleukin 12 receptor, beta 1
IL12RB2 interleukin 12 receptor, beta 2
IL21 interleukin 21
IL24 interleukin 24
INADL InaD-like (Drosophila)
INVS inversin
IPO7 importin 7
IRX1 iroquois homeobox 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGB4 integrin, beta 4
ITPK1 inositol-tetrakisphosphate 1-kinase
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JAK2 Janus kinase 2
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCTD14 potassium channel tetramerization domain containing 14
KDM4A lysine (K)-specific demethylase 4A
KIAA1033 KIAA1033
KIF2C kinesin family member 2C
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
KPNA6 karyopherin alpha 6 (importin alpha 7)
KTI12 KTI12 homolog, chromatin associated (S. cerevisiae)
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAMB1 laminin, beta 1
LAP3 leucine aminopeptidase 3
LARP1 La ribonucleoprotein domain family, member 1
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LHX1 LIM homeobox 1
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
LIMA1 LIM domain and actin binding 1
LINC01555 long intergenic non-protein coding RNA 1555
LOC100272216 uncharacterized LOC100272216
LOC613037 nuclear pore complex interacting protein pseudogene
LPAR3 lysophosphatidic acid receptor 3
LRRC40 leucine rich repeat containing 40
LRRC41 leucine rich repeat containing 41
LRRC42 leucine rich repeat containing 42
LRRC59 leucine rich repeat containing 59
LRRC8C leucine rich repeat containing 8 family, member C
LTBP1 latent transforming growth factor beta binding protein 1
MAGOH mago-nashi homolog, proliferation-associated (Drosophila)
MAP7D1 MAP7 domain containing 1
MARCH4 membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
MBNL2 muscleblind-like splicing regulator 2
MESDC2 mesoderm development candidate 2
MFSD2A major facilitator superfamily domain containing 2A
MICB MHC class I polypeptide-related sequence B
MIER1 mesoderm induction early response 1, transcriptional regulator
MLKL mixed lineage kinase domain-like
MMP12 matrix metallopeptidase 12
MMP3 matrix metallopeptidase 3
MOV10 Mov10 RISC complex RNA helicase
MS4A14 membrane-spanning 4-domains, subfamily A, member 14
MST1R macrophage stimulating 1 receptor
MTF2 metal response element binding transcription factor 2
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
MYD88 myeloid differentiation primary response 88
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit
NAV1 neuron navigator 1
NBPF9 neuroblastoma breakpoint family, member 9
NDC1 NDC1 transmembrane nucleoporin
NDE1 nudE neurodevelopment protein 1
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
NLGN4Y neuroligin 4, Y-linked
NLRP3 NLR family, pyrin domain containing 3
NMI N-myc (and STAT) interactor
NRGN neurogranin (protein kinase C substrate, RC3)
NT5E 5'-nucleotidase, ecto (CD73)
NUB1 negative regulator of ubiquitin-like proteins 1
NUDCD1 NudC domain containing 1
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR10J1 olfactory receptor, family 10, subfamily J, member 1
OR1D4 olfactory receptor, family 1, subfamily D, member 4 (gene/pseudogene)
OR1J1 olfactory receptor, family 1, subfamily J, member 1
OR2L1P olfactory receptor, family 2, subfamily L, member 1 pseudogene
OR2M4 olfactory receptor, family 2, subfamily M, member 4
OR2T8 olfactory receptor, family 2, subfamily T, member 8
OR2W3 olfactory receptor, family 2, subfamily W, member 3
ORC1 origin recognition complex, subunit 1
OSBPL10 oxysterol binding protein-like 10
OXSR1 oxidative stress responsive 1
PAPD5 PAP associated domain containing 5
PARP12 poly (ADP-ribose) polymerase family, member 12
PARP3 poly (ADP-ribose) polymerase family, member 3
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative)
PATL1 protein associated with topoisomerase II homolog 1 (yeast)
PCDH7 protocadherin 7
PDGFA platelet-derived growth factor alpha polypeptide
PFAS phosphoribosylformylglycinamidine synthase
PHC2 polyhomeotic homolog 2 (Drosophila)
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PML promyelocytic leukemia
POLM polymerase (DNA directed), mu
POTEM POTE ankyrin domain family, member M
PRF1 perforin 1 (pore forming protein)
PRMT8 protein arginine methyltransferase 8
PROCR protein C receptor, endothelial
PROSER2 proline and serine rich 2
PRPF38B pre-mRNA processing factor 38B
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
PRRT4 proline-rich transmembrane protein 4
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PTCD2 pentatricopeptide repeat domain 2
PTP4A2 protein tyrosine phosphatase type IVA, member 2
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PTPRG protein tyrosine phosphatase, receptor type, G
PTRF polymerase I and transcript release factor
PTTG2 pituitary tumor-transforming 2
PWP1 PWP1 homolog (S. cerevisiae)
PXN paxillin
RAB35 RAB35, member RAS oncogene family
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RABGGTB Rab geranylgeranyltransferase, beta subunit
RAG1 recombination activating gene 1
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RBM7 RNA binding motif protein 7
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RETNLB resistin like beta
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RIF1 replication timing regulatory factor 1
RIMKLB ribosomal modification protein rimK-like family member B
RIOK2 RIO kinase 2
RNF213 ring finger protein 213
RNF220 ring finger protein 220
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RRAGC Ras-related GTP binding C
RTCA RNA 3'-terminal phosphate cyclase
S100PBP S100P binding protein
SAMD9L sterile alpha motif domain containing 9-like
SAMHD1 SAM domain and HD domain 1
SASS6 spindle assembly 6 homolog (C. elegans)
SERBP1 SERPINE1 mRNA binding protein 1
SERINC2 serine incorporator 2
SET SET nuclear proto-oncogene
SETX senataxin
SF1 splicing factor 1
SF3A3 splicing factor 3a, subunit 3, 60kDa
SFMBT1 Scm-like with four mbt domains 1
SFPQ splicing factor proline/glutamine-rich
SH2B3 SH2B adaptor protein 3
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIK3 SIK family kinase 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC25A30 solute carrier family 25, member 30
SLC2A7 solute carrier family 2 (facilitated glucose transporter), member 7
SLC30A7 solute carrier family 30 (zinc transporter), member 7
SLC35F3 solute carrier family 35, member F3
SLC38A5 solute carrier family 38, member 5
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLFN5 schlafen family member 5
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMC5 structural maintenance of chromosomes 5
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNIP1 Smad nuclear interacting protein 1
SNX7 sorting nexin 7
SPATS2 spermatogenesis associated, serine-rich 2
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPIN1 spindlin 1
SPOCD1 SPOC domain containing 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPRY4 sprouty homolog 4 (Drosophila)
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRBD1 S1 RNA binding domain 1
SRFBP1 serum response factor binding protein 1
SRPK2 SRSF protein kinase 2
SSH1 slingshot protein phosphatase 1
SSH2 slingshot protein phosphatase 2
SSMEM1 serine-rich single-pass membrane protein 1
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
ST5 suppression of tumorigenicity 5
STAT1 signal transducer and activator of transcription 1, 91kDa
STIL SCL/TAL1 interrupting locus
STOM stomatin
STRIP2 striatin interacting protein 2
STXBP3 syntaxin binding protein 3
SUSD1 sushi domain containing 1
SYT16 synaptotagmin XVI
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
TAOK3 TAO kinase 3
TBC1D2 TBC1 domain family, member 2
TCERG1 transcription elongation regulator 1
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TENM2 teneurin transmembrane protein 2
TEX10 testis expressed 10
TGFBR1 transforming growth factor, beta receptor 1
THRAP3 thyroid hormone receptor associated protein 3
TLL1 tolloid-like 1
TMED5 transmembrane emp24 protein transport domain containing 5
TMEM170A transmembrane protein 170A
TMEM229B transmembrane protein 229B
TMEM43 transmembrane protein 43
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNS4 tensin 4
TOE1 target of EGR1, member 1 (nuclear)
TRIM21 tripartite motif containing 21
TRIM32 tripartite motif containing 32
TRIM58 tripartite motif containing 58
TRIM6 tripartite motif containing 6
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TSPAN4 tetraspanin 4
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TSSK1B testis-specific serine kinase 1B
TTC4 tetratricopeptide repeat domain 4
TTLL11 tubulin tyrosine ligase-like family member 11
TXLNA taxilin alpha
TXNIP thioredoxin interacting protein
TYW3 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBASH3B ubiquitin associated and SH3 domain containing B
UBE2L6 ubiquitin-conjugating enzyme E2L 6
USP1 ubiquitin specific peptidase 1
USP10 ubiquitin specific peptidase 10
USP24 ubiquitin specific peptidase 24
USP28 ubiquitin specific peptidase 28
USP33 ubiquitin specific peptidase 33
UTP15 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VAV2 vav 2 guanine nucleotide exchange factor
VEGFC vascular endothelial growth factor C
WARS tryptophanyl-tRNA synthetase
WDR36 WD repeat domain 36
WDR91 WD repeat domain 91
WISP3 WNT1 inducible signaling pathway protein 3
WLS wntless Wnt ligand secretion mediator
XAF1 XIAP associated factor 1
YARS tyrosyl-tRNA synthetase
YBX1 Y box binding protein 1
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZC3H14 zinc finger CCCH-type containing 14
ZFP1 ZFP1 zinc finger protein
ZFP36L2 ZFP36 ring finger protein-like 2
ZFP69 ZFP69 zinc finger protein
ZFYVE9 zinc finger, FYVE domain containing 9
ZMPSTE24 zinc metallopeptidase STE24
ZMYM1 zinc finger, MYM-type 1
ZMYM4 zinc finger, MYM-type 4
ZNF114 zinc finger protein 114
ZNF200 zinc finger protein 200
ZNF281 zinc finger protein 281
ZNF318 zinc finger protein 318
ZNF644 zinc finger protein 644
ZNFX1 zinc finger, NFX1-type containing 1
ZNHIT6 zinc finger, HIT-type containing 6
ZPLD1 zona pellucida-like domain containing 1
ZZZ3 zinc finger, ZZ-type containing 3

low expression

Symbol Name
TLE3 transducin-like enhancer of split 3