Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7372-01A-11R-2016-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

306 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7372-01A-11R-2016-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAK1 AP2 associated kinase 1
ABHD6 abhydrolase domain containing 6
ACSM4 acyl-CoA synthetase medium-chain family member 4
ADAP2 ArfGAP with dual PH domains 2
ADARB1 adenosine deaminase, RNA-specific, B1
ADCY9 adenylate cyclase 9
AJUBA ajuba LIM protein
ALKBH2 alkB, alkylation repair homolog 2 (E. coli)
ALKBH5 AlkB family member 5, RNA demethylase
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKRD13A ankyrin repeat domain 13A
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
APCDD1 adenomatosis polyposis coli down-regulated 1
APTX aprataxin
ARHGEF39 Rho guanine nucleotide exchange factor (GEF) 39
ARL5A ADP-ribosylation factor-like 5A
ATG9A autophagy related 9A
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATXN1L ataxin 1-like
ATXN2 ataxin 2
AVPR1A arginine vasopressin receptor 1A
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCR breakpoint cluster region
BMP2K BMP2 inducible kinase
BRAP BRCA1 associated protein
BTBD11 BTB (POZ) domain containing 11
C17ORF51 chromosome 17 open reading frame 51
C17ORF59 chromosome 17 open reading frame 59
C22ORF29 chromosome 22 open reading frame 29
C2ORF16 chromosome 2 open reading frame 16
C9ORF131 chromosome 9 open reading frame 131
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CHMP5 charged multivesicular body protein 5
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CKAP4 cytoskeleton-associated protein 4
CLCN5 chloride channel, voltage-sensitive 5
CMTM4 CKLF-like MARVEL transmembrane domain containing 4
CMTR2 cap methyltransferase 2
COG8 component of oligomeric golgi complex 8
CORO1C coronin, actin binding protein, 1C
CPA3 carboxypeptidase A3 (mast cell)
CREB3 cAMP responsive element binding protein 3
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRY1 cryptochrome circadian clock 1
CTCF CCCTC-binding factor (zinc finger protein)
CTNS cystinosin, lysosomal cystine transporter
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCAF12 DDB1 and CUL4 associated factor 12
DCTN1 dynactin 1
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DGCR2 DiGeorge syndrome critical region gene 2
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DOK4 docking protein 4
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
DQX1 DEAQ box RNA-dependent ATPase 1
DSC2 desmocollin 2
DSC3 desmocollin 3
DSG1 desmoglein 1
DSG3 desmoglein 3
DSP desmoplakin
DTWD2 DTW domain containing 2
DUSP18 dual specificity phosphatase 18
DYTN dystrotelin
EFR3B EFR3 homolog B (S. cerevisiae)
EGFL6 EGF-like-domain, multiple 6
ERCC4 excision repair cross-complementation group 4
EXOC6B exocyst complex component 6B
FAM109A family with sequence similarity 109, member A
FAM138D family with sequence similarity 138, member D
FAM155B family with sequence similarity 155, member B
FAM162B family with sequence similarity 162, member B
FAM217B family with sequence similarity 217, member B
FAM57A family with sequence similarity 57, member A
FAM83G family with sequence similarity 83, member G
FAM84A family with sequence similarity 84, member A
FAM98A family with sequence similarity 98, member A
FAT4 FAT atypical cadherin 4
FBXO30 F-box protein 30
FBXO33 F-box protein 33
FGF18 fibroblast growth factor 18
FIBIN fin bud initiation factor homolog (zebrafish)
FICD FIC domain containing
GAS2L1 growth arrest-specific 2 like 1
GATSL2 GATS protein-like 2
GBA2 glucosidase, beta (bile acid) 2
GFOD2 glucose-fructose oxidoreductase domain containing 2
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GID4 GID complex subunit 4
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GJA1 gap junction protein, alpha 1, 43kDa
GLTP glycolipid transfer protein
GLTPD2 glycolipid transfer protein domain containing 2
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPR180 G protein-coupled receptor 180
GSDMA gasdermin A
HCCS holocytochrome c synthase
HEATR5A HEAT repeat containing 5A
HINT2 histidine triad nucleotide binding protein 2
HIRA histone cell cycle regulator
HIST1H4H histone cluster 1, H4h
HIST1H4K histone cluster 1, H4k
IFNA8 interferon, alpha 8
IL17RA interleukin 17 receptor A
IPMK inositol polyphosphate multikinase
JDP2 Jun dimerization protein 2
KCTD10 potassium channel tetramerization domain containing 10
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KHNYN KH and NYN domain containing
KIAA1919 KIAA1919
KIF5B kinesin family member 5B
KLF13 Kruppel-like factor 13
KLHL28 kelch-like family member 28
LELP1 late cornified envelope-like proline-rich 1
LIMK2 LIM domain kinase 2
LINC00293 long intergenic non-protein coding RNA 293
LOC100130264 uncharacterized LOC100130264
LOC100134868 uncharacterized LOC100134868
LOC284788 uncharacterized LOC284788
LOC285629 uncharacterized LOC285629
LOC727896 cysteine and histidine-rich domain (CHORD) containing 1 pseudogene
LPAR5 lysophosphatidic acid receptor 5
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK6 mitogen-activated protein kinase 6
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MBNL2 muscleblind-like splicing regulator 2
MCFD2 multiple coagulation factor deficiency 2
MCM4 minichromosome maintenance complex component 4
MID1 midline 1
MID2 midline 2
MN1 meningioma (disrupted in balanced translocation) 1
MOSPD1 motile sperm domain containing 1
MPZL3 myelin protein zero-like 3
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MSMP microseminoprotein, prostate associated
MTIF2 mitochondrial translational initiation factor 2
MTSS1L metastasis suppressor 1-like
MYO1H myosin IH
MYO5A myosin VA (heavy chain 12, myoxin)
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit
NDEL1 nudE neurodevelopment protein 1-like 1
NDRG4 NDRG family member 4
NEU2 sialidase 2 (cytosolic sialidase)
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFX1 nuclear transcription factor, X-box binding 1
NIN ninein (GSK3B interacting protein)
NOL6 nucleolar protein 6 (RNA-associated)
NOP9 NOP9 nucleolar protein
NPR2 natriuretic peptide receptor 2
ODC1 ornithine decarboxylase 1
OMP olfactory marker protein
OR51E1 olfactory receptor, family 51, subfamily E, member 1
OR52K2 olfactory receptor, family 52, subfamily K, member 2
OSBP oxysterol binding protein
OTOP2 otopetrin 2
OTOP3 otopetrin 3
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PAPD5 PAP associated domain containing 5
PCBP1 poly(rC) binding protein 1
PCDHGA10 protocadherin gamma subfamily A, 10
PCYOX1 prenylcysteine oxidase 1
PEX26 peroxisomal biogenesis factor 26
PFAS phosphoribosylformylglycinamidine synthase
PGM3 phosphoglucomutase 3
PI15 peptidase inhibitor 15
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PIRT phosphoinositide-interacting regulator of transient receptor potential channels
PITPNM3 PITPNM family member 3
PLA2G4F phospholipase A2, group IVF
PLA2R1 phospholipase A2 receptor 1, 180kDa
PLBD1 phospholipase B domain containing 1
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLD2 phospholipase D2
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PRCP prolylcarboxypeptidase (angiotensinase C)
PRDM11 PR domain containing 11
PRDM4 PR domain containing 4
PREB prolactin regulatory element binding
PRICKLE1 prickle homolog 1 (Drosophila)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRR14L proline rich 14-like
PRSS3 protease, serine, 3
PSKH1 protein serine kinase H1
PWP1 PWP1 homolog (S. cerevisiae)
RAB10 RAB10, member RAS oncogene family
RAB1A RAB1A, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RANBP10 RAN binding protein 10
RAP2A RAP2A, member of RAS oncogene family
RBM23 RNA binding motif protein 23
RD3 retinal degeneration 3
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RGS5 regulator of G-protein signaling 5
RIC8B RIC8 guanine nucleotide exchange factor B
RNF167 ring finger protein 167
RNF185 ring finger protein 185
RPA1 replication protein A1, 70kDa
RPTOR regulatory associated protein of MTOR, complex 1
RUNDC3B RUN domain containing 3B
RUSC2 RUN and SH3 domain containing 2
SART3 squamous cell carcinoma antigen recognized by T cells 3
SEC23A Sec23 homolog A (S. cerevisiae)
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SERINC3 serine incorporator 3
SESN3 sestrin 3
SF3A1 splicing factor 3a, subunit 1, 120kDa
SFRP1 secreted frizzled-related protein 1
SHPK sedoheptulokinase
SHROOM2 shroom family member 2
SLC16A13 solute carrier family 16, member 13
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC30A6 solute carrier family 30 (zinc transporter), member 6
SLC35E4 solute carrier family 35, member E4
SLC35F6 solute carrier family 35, member F6
SLC38A7 solute carrier family 38, member 7
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC5A10 solute carrier family 5 (sodium/sugar cotransporter), member 10
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG6 SMG6 nonsense mediated mRNA decay factor
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SMYD4 SET and MYND domain containing 4
SNAR-G1 small ILF3/NF90-associated RNA G1
SNORA12 small nucleolar RNA, H/ACA box 12
SNORA45A small nucleolar RNA, H/ACA box 45A
SNORA45B small nucleolar RNA, H/ACA box 45B
SNORA84 small nucleolar RNA, H/ACA box 84
SNPH syntaphilin
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SNX16 sorting nexin 16
SOCS5 suppressor of cytokine signaling 5
SOCS7 suppressor of cytokine signaling 7
SPDYE4 speedy/RINGO cell cycle regulator family member E4
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPTBN2 spectrin, beta, non-erythrocytic 2
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
TANGO6 transport and golgi organization 6 homolog (Drosophila)
TBL1X transducin (beta)-like 1X-linked
TBX1 T-box 1
TCHP trichoplein, keratin filament binding
TCP11L2 t-complex 11, testis-specific-like 2
TCTA T-cell leukemia translocation altered
TERF2 telomeric repeat binding factor 2
TESK1 testis-specific kinase 1
TEX261 testis expressed 261
TLN1 talin 1
TM4SF19 transmembrane 4 L six family member 19
TMEM110 transmembrane protein 110
TMEM185B transmembrane protein 185B
TMEM214 transmembrane protein 214
TMEM252 transmembrane protein 252
TMEM263 transmembrane protein 263
TMEM86A transmembrane protein 86A
TMX1 thioredoxin-related transmembrane protein 1
TNN tenascin N
TOP3A topoisomerase (DNA) III alpha
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TTC7A tetratricopeptide repeat domain 7A
TTTY4C testis-specific transcript, Y-linked 4C (non-protein coding)
TWIST2 twist family bHLH transcription factor 2
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)
UBAP2 ubiquitin associated protein 2
UBE2R2 ubiquitin-conjugating enzyme E2R 2
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
UBE3B ubiquitin protein ligase E3B
UNC13B unc-13 homolog B (C. elegans)
USP22 ubiquitin specific peptidase 22
USP30 ubiquitin specific peptidase 30
VAC14 Vac14 homolog (S. cerevisiae)
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WDR24 WD repeat domain 24
WWC3 WWC family member 3
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XKRX XK, Kell blood group complex subunit-related, X-linked
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
ZBTB5 zinc finger and BTB domain containing 5
ZHX3 zinc fingers and homeoboxes 3
ZIM3 zinc finger, imprinted 3
ZNF319 zinc finger protein 319
ZNF70 zinc finger protein 70
ZNF843 zinc finger protein 843
ZSCAN12P1 zinc finger and SCAN domain containing 12 pseudogene 1
ZSWIM3 zinc finger, SWIM-type containing 3

low expression

Symbol Name
C1ORF27 chromosome 1 open reading frame 27
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
R3HCC1L R3H domain and coiled-coil containing 1-like