Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7371-01A-11R-2016-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

391 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7371-01A-11R-2016-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABHD15 abhydrolase domain containing 15
ABI1 abl-interactor 1
ACBD5 acyl-CoA binding domain containing 5
ACER3 alkaline ceramidase 3
ACSM4 acyl-CoA synthetase medium-chain family member 4
ADAM32 ADAM metallopeptidase domain 32
ADD2 adducin 2 (beta)
ADGRE3 adhesion G protein-coupled receptor E3
ADGRL1 adhesion G protein-coupled receptor L1
ADNP2 ADNP homeobox 2
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AGO1 argonaute RISC catalytic component 1
AGO4 argonaute RISC catalytic component 4
AHSG alpha-2-HS-glycoprotein
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3
ALG8 ALG8, alpha-1,3-glucosyltransferase
ALK anaplastic lymphoma receptor tyrosine kinase
AMER1 APC membrane recruitment protein 1
ANAPC1 anaphase promoting complex subunit 1
ANKRD26 ankyrin repeat domain 26
ANKRD42 ankyrin repeat domain 42
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AQP11 aquaporin 11
ARFGEF3 ARFGEF family member 3
ARHGAP19 Rho GTPase activating protein 19
ARHGAP35 Rho GTPase activating protein 35
ARID2 AT rich interactive domain 2 (ARID, RFX-like)
ARL13B ADP-ribosylation factor-like 13B
ARSD arylsulfatase D
ASIC1 acid sensing (proton gated) ion channel 1
ASS1 argininosuccinate synthase 1
ATF1 activating transcription factor 1
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATRNL1 attractin-like 1
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTNL8 butyrophilin-like 8
C10ORF12 chromosome 10 open reading frame 12
C18ORF54 chromosome 18 open reading frame 54
C22ORF29 chromosome 22 open reading frame 29
C4BPA complement component 4 binding protein, alpha
C6ORF223 chromosome 6 open reading frame 223
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CALCB calcitonin-related polypeptide beta
CAPN8 calpain 8
CBX6 chromobox homolog 6
CCDC117 coiled-coil domain containing 117
CCDC90B coiled-coil domain containing 90B
CCNJ cyclin J
CCR4 chemokine (C-C motif) receptor 4
CD163L1 CD163 molecule-like 1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKL5 cyclin-dependent kinase-like 5
CEMIP cell migration inducing protein, hyaluronan binding
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLCN2 chloride channel, voltage-sensitive 2
CLDN2 claudin 2
CLDN5 claudin 5
CLIC6 chloride intracellular channel 6
CMTM2 CKLF-like MARVEL transmembrane domain containing 2
CMTM4 CKLF-like MARVEL transmembrane domain containing 4
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNOT1 CCR4-NOT transcription complex, subunit 1
CNTNAP2 contactin associated protein-like 2
COCH cochlin
COL15A1 collagen, type XV, alpha 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
COMT catechol-O-methyltransferase
CPD carboxypeptidase D
CPXM2 carboxypeptidase X (M14 family), member 2
CREG2 cellular repressor of E1A-stimulated genes 2
CRHR2 corticotropin releasing hormone receptor 2
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CRLF2 cytokine receptor-like factor 2
CSF3R colony stimulating factor 3 receptor (granulocyte)
CT45A4 cancer/testis antigen family 45, member A4
CT45A6 cancer/testis antigen family 45, member A6
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
CTPS2 CTP synthase 2
CXCR1 chemokine (C-X-C motif) receptor 1
CXORF23 chromosome X open reading frame 23
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DCAF12L2 DDB1 and CUL4 associated factor 12-like 2
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1
DDIAS DNA damage-induced apoptosis suppressor
DESI2 desumoylating isopeptidase 2
DGKG diacylglycerol kinase, gamma 90kDa
DGKK diacylglycerol kinase, kappa
DHCR7 7-dehydrocholesterol reductase
DIS3L DIS3 like exosome 3'-5' exoribonuclease
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DLEU2L deleted in lymphocytic leukemia 2-like
DMRT3 doublesex and mab-3 related transcription factor 3
DPPA2 developmental pluripotency associated 2
DYNLT3 dynein, light chain, Tctex-type 3
E2F7 E2F transcription factor 7
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
EPHA7 EPH receptor A7
ERC2 ELKS/RAB6-interacting/CAST family member 2
ETV5 ets variant 5
EXOC6 exocyst complex component 6
FADS1 fatty acid desaturase 1
FAM105A family with sequence similarity 105, member A
FAM160B1 family with sequence similarity 160, member B1
FAM168A family with sequence similarity 168, member A
FAM181B family with sequence similarity 181, member B
FAM35DP family with sequence similarity 35, member A pseudogene
FAM45B family with sequence similarity 45, member A pseudogene
FAM66A family with sequence similarity 66, member A
FAT4 FAT atypical cadherin 4
FCAR Fc fragment of IgA receptor
FCGBP Fc fragment of IgG binding protein
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FETUB fetuin B
FITM2 fat storage-inducing transmembrane protein 2
FMR1-AS1 FMR1 antisense RNA 1
FOXB2 forkhead box B2
FPR1 formyl peptide receptor 1
FRAS1 Fraser extracellular matrix complex subunit 1
FRK fyn-related Src family tyrosine kinase
FRRS1L ferric-chelate reductase 1-like
FUBP3 far upstream element (FUSE) binding protein 3
FZD3 frizzled class receptor 3
GALNT4 polypeptide N-acetylgalactosaminyltransferase 4
GDAP1 ganglioside induced differentiation associated protein 1
GFM1 G elongation factor, mitochondrial 1
GLUL glutamate-ammonia ligase
GLYATL2 glycine-N-acyltransferase-like 2
GPR15 G protein-coupled receptor 15
GPR180 G protein-coupled receptor 180
GPRC5D G protein-coupled receptor, class C, group 5, member D
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GRK5 G protein-coupled receptor kinase 5
GTSE1 G-2 and S-phase expressed 1
GTSE1-AS1 GTSE1 antisense RNA 1 (head to head)
GYG2 glycogenin 2
HAP1 huntingtin-associated protein 1
HHEX hematopoietically expressed homeobox
HIC2 hypermethylated in cancer 2
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IDE insulin-degrading enzyme
IL7R interleukin 7 receptor
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2
ITGA8 integrin, alpha 8
KAT6B K(lysine) acetyltransferase 6B
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KGFLP1 fibroblast growth factor 7 pseudogene
KIAA1324L KIAA1324-like
KIAA2022 KIAA2022
KIF1A kinesin family member 1A
KIF5B kinesin family member 5B
KLHL11 kelch-like family member 11
KLHL15 kelch-like family member 15
KLLN killin, p53-regulated DNA replication inhibitor
KPNA4 karyopherin alpha 4 (importin alpha 3)
KSR2 kinase suppressor of ras 2
LATS1 large tumor suppressor kinase 1
LAYN layilin
LCLAT1 lysocardiolipin acyltransferase 1
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LINC00235 long intergenic non-protein coding RNA 235
LINC00575 long intergenic non-protein coding RNA 575
LMBR1 limb development membrane protein 1
LOC100271832 uncharacterized LOC100271832
LOC100272217 uncharacterized LOC100272217
LOC283731 uncharacterized LOC283731
LOC613037 nuclear pore complex interacting protein pseudogene
LOC646762 uncharacterized LOC646762
LPP LIM domain containing preferred translocation partner in lipoma
LPPR4 lipid phosphate phosphatase-related protein type 4
LRRC19 leucine rich repeat containing 19
LRRC34 leucine rich repeat containing 34
LRRTM3 leucine rich repeat transmembrane neuronal 3
LZTR1 leucine-zipper-like transcription regulator 1
MANEA mannosidase, endo-alpha
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MASTL microtubule associated serine/threonine kinase-like
MBTPS2 membrane-bound transcription factor peptidase, site 2
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
METTL24 methyltransferase like 24
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MKX mohawk homeobox
MORC2 MORC family CW-type zinc finger 2
MPV17L MPV17 mitochondrial membrane protein-like
MSL3 male-specific lethal 3 homolog (Drosophila)
MTMR3 myotubularin related protein 3
MUC5B mucin 5B, oligomeric mucus/gel-forming
NADSYN1 NAD synthetase 1
NARS asparaginyl-tRNA synthetase
NCEH1 neutral cholesterol ester hydrolase 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEU3 sialidase 3 (membrane sialidase)
NEUROD2 neuronal differentiation 2
NEUROG3 neurogenin 3
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NHLRC2 NHL repeat containing 2
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
NKX3-1 NK3 homeobox 1
NLRP12 NLR family, pyrin domain containing 12
NOMO3 NODAL modulator 3
NRXN2 neurexin 2
NT5C3B 5'-nucleotidase, cytosolic IIIB
NUDT16P1 nudix (nucleoside diphosphate linked moiety X)-type motif 16 pseudogene 1
NXPE2 neurexophilin and PC-esterase domain family, member 2
OGFRL1 opioid growth factor receptor-like 1
OR1L1 olfactory receptor, family 1, subfamily L, member 1
OR52E4 olfactory receptor, family 52, subfamily E, member 4
OR52I1 olfactory receptor, family 52, subfamily I, member 1
OR52K2 olfactory receptor, family 52, subfamily K, member 2
OR56B4 olfactory receptor, family 56, subfamily B, member 4
OR6C70 olfactory receptor, family 6, subfamily C, member 70
OSBP2 oxysterol binding protein 2
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PCAT4 prostate cancer associated transcript 4 (non-protein coding)
PCDH19 protocadherin 19
PCDHA10 protocadherin alpha 10
PCDHA4 protocadherin alpha 4
PCDHAC2 protocadherin alpha subfamily C, 2
PCDHB10 protocadherin beta 10
PCDHB5 protocadherin beta 5
PCF11 PCF11 cleavage and polyadenylation factor subunit
PCGF5 polycomb group ring finger 5
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1
PENK proenkephalin
PGM2L1 phosphoglucomutase 2-like 1
PHEX phosphate regulating endopeptidase homolog, X-linked
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
PLGLA plasminogen-like A (pseudogene)
PLS1 plastin 1
POLI polymerase (DNA directed) iota
POU4F2 POU class 4 homeobox 2
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRCP prolylcarboxypeptidase (angiotensinase C)
PRDM14 PR domain containing 14
PRDX4 peroxiredoxin 4
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
PRLR prolactin receptor
PROK2 prokineticin 2
PRR14L proline rich 14-like
PRTFDC1 phosphoribosyl transferase domain containing 1
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTCHD3 patched domain containing 3
PTPN20 protein tyrosine phosphatase, non-receptor type 20
PYDC2 pyrin domain containing 2
PYGO1 pygopus family PHD finger 1
QSER1 glutamine and serine rich 1
RAB18 RAB18, member RAS oncogene family
RAB30 RAB30, member RAS oncogene family
RAB39B RAB39B, member RAS oncogene family
RANBP1 RAN binding protein 1
RASGRP4 RAS guanyl releasing protein 4
RASL11A RAS-like, family 11, member A
RCOR2 REST corepressor 2
RFX7 regulatory factor X, 7
RGS7BP regulator of G-protein signaling 7 binding protein
RIMBP3 RIMS binding protein 3
RNF169 ring finger protein 169
RNF24 ring finger protein 24
RPH3A rabphilin 3A
RPL39L ribosomal protein L39-like
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RSF1 remodeling and spacing factor 1
RSRC1 arginine/serine-rich coiled-coil 1
RTN4R reticulon 4 receptor
SALL1 spalt-like transcription factor 1
SCAMP5 secretory carrier membrane protein 5
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC14L4 SEC14-like 4 (S. cerevisiae)
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SERTAD4 SERTA domain containing 4
SERTM1 serine-rich and transmembrane domain containing 1
SF3A1 splicing factor 3a, subunit 1, 120kDa
SF3B3 splicing factor 3b, subunit 3, 130kDa
SGPL1 sphingosine-1-phosphate lyase 1
SHROOM2 shroom family member 2
SIGLEC5 sialic acid binding Ig-like lectin 5
SLC16A9 solute carrier family 16, member 9
SLC26A8 solute carrier family 26 (anion exchanger), member 8
SLC35E4 solute carrier family 35, member E4
SLC39A3 solute carrier family 39 (zinc transporter), member 3
SLC7A4 solute carrier family 7, member 4
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SLITRK4 SLIT and NTRK-like family, member 4
SNORA23 small nucleolar RNA, H/ACA box 23
SNORA45B small nucleolar RNA, H/ACA box 45B
SNORA71C small nucleolar RNA, H/ACA box 71C
SOCS7 suppressor of cytokine signaling 7
SOGA1 suppressor of glucose, autophagy associated 1
SOX21 SRY (sex determining region Y)-box 21
SPAST spastin
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPRED1 sprouty-related, EVH1 domain containing 1
SPRN shadow of prion protein homolog (zebrafish)
SPRY2 sprouty homolog 2 (Drosophila)
SST somatostatin
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
STK32B serine/threonine kinase 32B
SYNJ2 synaptojanin 2
SYT14 synaptotagmin XIV
SYT9 synaptotagmin IX
SYTL5 synaptotagmin-like 5
TACR3 tachykinin receptor 3
TBCCD1 TBCC domain containing 1
TBL1X transducin (beta)-like 1X-linked
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBX20 T-box 20
TCEANC transcription elongation factor A (SII) N-terminal and central domain containing
TCN2 transcobalamin II
TENM4 teneurin transmembrane protein 4
TGOLN2 trans-golgi network protein 2
THAP7 THAP domain containing 7
THNSL1 threonine synthase-like 1 (S. cerevisiae)
THSD7B thrombospondin, type I, domain containing 7B
TM9SF3 transmembrane 9 superfamily member 3
TMEM179 transmembrane protein 179
TMEM180 transmembrane protein 180
TMTC3 transmembrane and tetratricopeptide repeat containing 3
TMX3 thioredoxin-related transmembrane protein 3
TNIP3 TNFAIP3 interacting protein 3
TRIM13 tripartite motif containing 13
TRIM59 tripartite motif containing 59
TRUB1 TruB pseudouridine (psi) synthase family member 1
TSHZ2 teashirt zinc finger homeobox 2
TSPAN11 tetraspanin 11
TSPAN18 tetraspanin 18
TSPYL5 TSPY-like 5
TUBGCP4 tubulin, gamma complex associated protein 4
TUG1 taurine up-regulated 1 (non-protein coding)
TXLNG taxilin gamma
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UGT3A2 UDP glycosyltransferase 3 family, polypeptide A2
UGT8 UDP glycosyltransferase 8
ULBP1 UL16 binding protein 1
UNC119B unc-119 homolog B (C. elegans)
USP51 ubiquitin specific peptidase 51
WBSCR28 Williams-Beuren syndrome chromosome region 28
WDR7 WD repeat domain 7
XIST X inactive specific transcript (non-protein coding)
XRRA1 X-ray radiation resistance associated 1
YME1L1 YME1-like 1 ATPase
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
ZBED4 zinc finger, BED-type containing 4
ZBTB38 zinc finger and BTB domain containing 38
ZC3H4 zinc finger CCCH-type containing 4
ZDHHC2 zinc finger, DHHC-type containing 2
ZFX zinc finger protein, X-linked
ZNF124 zinc finger protein 124
ZNF217 zinc finger protein 217
ZNF280B zinc finger protein 280B
ZNF536 zinc finger protein 536
ZNF592 zinc finger protein 592
ZNF639 zinc finger protein 639
ZNF74 zinc finger protein 74
ZNRF3 zinc and ring finger 3
ZPBP zona pellucida binding protein
ZSCAN29 zinc finger and SCAN domain containing 29
ZSWIM5 zinc finger, SWIM-type containing 5

low expression

Symbol Name
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
USP33 ubiquitin specific peptidase 33