Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6491-01A-11R-1873-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

261 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6491-01A-11R-1873-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACTL8 actin-like 8
ADAMTSL5 ADAMTS-like 5
ADGRF4 adhesion G protein-coupled receptor F4
AFAP1L1 actin filament associated protein 1-like 1
AHNAK2 AHNAK nucleoprotein 2
AIF1L allograft inflammatory factor 1-like
AKR1B15 aldo-keto reductase family 1, member B15
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
AMOTL1 angiomotin like 1
AMPD3 adenosine monophosphate deaminase 3
ANXA2P1 annexin A2 pseudogene 1
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
ARF6 ADP-ribosylation factor 6
ATG14 autophagy related 14
ATG2A autophagy related 2A
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
BAIAP2 BAI1-associated protein 2
BDKRB1 bradykinin receptor B1
BDKRB2 bradykinin receptor B2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C10ORF76 chromosome 10 open reading frame 76
C11ORF68 chromosome 11 open reading frame 68
C11ORF80 chromosome 11 open reading frame 80
C17ORF105 chromosome 17 open reading frame 105
C18ORF25 chromosome 18 open reading frame 25
C9ORF129 chromosome 9 open reading frame 129
C9ORF57 chromosome 9 open reading frame 57
CAPN1 calpain 1, (mu/I) large subunit
CAV1 caveolin 1, caveolae protein, 22kDa
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CDA cytidine deaminase
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDH16 cadherin 16, KSP-cadherin
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CES2 carboxylesterase 2
CHD2 chromodomain helicase DNA binding protein 2
CHODL-AS1 CHODL antisense RNA 1
CLK3 CDC-like kinase 3
CNGA1 cyclic nucleotide gated channel alpha 1
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNTN1 contactin 1
CTIF CBP80/20-dependent translation initiation factor
CTSL3P cathepsin L family member 3, pseudogene
DAAM1 dishevelled associated activator of morphogenesis 1
DCAF5 DDB1 and CUL4 associated factor 5
DEFB103B defensin, beta 103B
DEFB106A defensin, beta 106A
DHRS7 dehydrogenase/reductase (SDR family) member 7
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DLX4 distal-less homeobox 4
DOCK4 dedicator of cytokinesis 4
DOCK5 dedicator of cytokinesis 5
DPF2 D4, zinc and double PHD fingers family 2
DPP3 dipeptidyl-peptidase 3
DQX1 DEAQ box RNA-dependent ATPase 1
DSC2 desmocollin 2
DSC3 desmocollin 3
DSG3 desmoglein 3
DSP desmoplakin
DYM dymeclin
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EDC3 enhancer of mRNA decapping 3
EHD1 EH-domain containing 1
EHD2 EH-domain containing 2
EIF4B eukaryotic translation initiation factor 4B
ELMSAN1 ELM2 and Myb/SANT-like domain containing 1
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans)
EPN1 epsin 1
EPN3 epsin 3
EPO erythropoietin
ERO1L ERO1-like (S. cerevisiae)
ESRP1 epithelial splicing regulatory protein 1
EXD2 exonuclease 3'-5' domain containing 2
EXOC6B exocyst complex component 6B
FAM138F family with sequence similarity 138, member F
FAM160A1 family with sequence similarity 160, member A1
FAM47B family with sequence similarity 47, member B
FAT1 FAT atypical cadherin 1
FER fer (fps/fes related) tyrosine kinase
FER1L6 fer-1-like family member 6
FGF11 fibroblast growth factor 11
FKSG29 FKSG29
FOSL1 FOS-like antigen 1
FOXP2 forkhead box P2
FRRS1 ferric-chelate reductase 1
GANC glucosidase, alpha; neutral C
GAREM GRB2 associated, regulator of MAPK1
GJB4 gap junction protein, beta 4, 30.3kDa
GKN1 gastrokine 1
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1
GSTP1 glutathione S-transferase pi 1
GSTTP1 glutathione S-transferase theta pseudogene 1
HAUS1 HAUS augmin-like complex, subunit 1
HDHD2 haloacid dehalogenase-like hydrolase domain containing 2
HEPHL1 hephaestin-like 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HES5 hes family bHLH transcription factor 5
HIST1H2AD histone cluster 1, H2ad
HIST1H2BD histone cluster 1, H2bd
HIST1H2BF histone cluster 1, H2bf
HIST1H2BG histone cluster 1, H2bg
HIST1H3D histone cluster 1, H3d
HIST1H3E histone cluster 1, H3e
HSPA4L heat shock 70kDa protein 4-like
IER3IP1 immediate early response 3 interacting protein 1
IGSF3 immunoglobulin superfamily, member 3
IL17C interleukin 17C
IL1RL1 interleukin 1 receptor-like 1
IL1RL2 interleukin 1 receptor-like 2
INVS inversin
IPMK inositol polyphosphate multikinase
IQGAP1 IQ motif containing GTPase activating protein 1
IRF6 interferon regulatory factor 6
JUP junction plakoglobin
KAT5 K(lysine) acetyltransferase 5
KCTD11 potassium channel tetramerization domain containing 11
KCTD9 potassium channel tetramerization domain containing 9
KDM2A lysine (K)-specific demethylase 2A
KIAA0586 KIAA0586
KIF13A kinesin family member 13A
KLC2 kinesin light chain 2
KLK10 kallikrein-related peptidase 10
KLK12 kallikrein-related peptidase 12
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT37 keratin 37, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRT6C keratin 6C, type II
KTN1 kinectin 1 (kinesin receptor)
KTN1-AS1 KTN1 antisense RNA 1
LCE3A late cornified envelope 3A
LCE3D late cornified envelope 3D
LDB1 LIM domain binding 1
LINC00319 long intergenic non-protein coding RNA 319
LINC00324 long intergenic non-protein coding RNA 324
LINC01559 long intergenic non-protein coding RNA 1559
LPAR3 lysophosphatidic acid receptor 3
LPPR5 lipid phosphate phosphatase-related protein type 5
LRSAM1 leucine rich repeat and sterile alpha motif containing 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBOAT4 membrane bound O-acyltransferase domain containing 4
MEN1 multiple endocrine neoplasia I
MOB3A MOB kinase activator 3A
MPI mannose phosphate isomerase
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MRPL49 mitochondrial ribosomal protein L49
MYO16 myosin XVI
MYO1E myosin IE
MYO3B myosin IIIB
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit
NAV3 neuron navigator 3
NDRG1 N-myc downstream regulated 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NHEJ1 nonhomologous end-joining factor 1
NIPAL3 NIPA-like domain containing 3
NLRC4 NLR family, CARD domain containing 4
NPNT nephronectin
NRG4 neuregulin 4
NTSR1 neurotensin receptor 1 (high affinity)
NUDT22 nudix (nucleoside diphosphate linked moiety X)-type motif 22
NUDT8 nudix (nucleoside diphosphate linked moiety X)-type motif 8
OR2A14 olfactory receptor, family 2, subfamily A, member 14
OR51T1 olfactory receptor, family 51, subfamily T, member 1
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
PACS1 phosphofurin acidic cluster sorting protein 1
PANX1 pannexin 1
PC pyruvate carboxylase
PCDHGB2 protocadherin gamma subfamily B, 2
PCDHGC5 protocadherin gamma subfamily C, 5
PCNXL4 pecanex-like 4 (Drosophila)
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PELI3 pellino E3 ubiquitin protein ligase family member 3
PFKP phosphofructokinase, platelet
PHF3 PHD finger protein 3
PIAS2 protein inhibitor of activated STAT, 2
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PKP1 plakophilin 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
PPARD peroxisome proliferator-activated receptor delta
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PPT2 palmitoyl-protein thioesterase 2
PSEN1 presenilin 1
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PYGL phosphorylase, glycogen, liver
RAB1B RAB1B, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RNF144B ring finger protein 144B
RNF39 ring finger protein 39
RPAP1 RNA polymerase II associated protein 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SCARNA9L small Cajal body-specific RNA 9-like
SCNN1D sodium channel, non voltage gated 1 delta subunit
SDR42E1 short chain dehydrogenase/reductase family 42E, member 1
SETBP1 SET binding protein 1
SF1 splicing factor 1
SF3B2 splicing factor 3b, subunit 2, 145kDa
SGK223 homolog of rat pragma of Rnd2
SH3GL1 SH3-domain GRB2-like 1
SLAMF9 SLAM family member 9
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD7 SMAD family member 7
SNCB synuclein, beta
SNX15 sorting nexin 15
SNX33 sorting nexin 33
SOS2 son of sevenless homolog 2 (Drosophila)
SOX15 SRY (sex determining region Y)-box 15
SPTBN2 spectrin, beta, non-erythrocytic 2
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRPK2 SRSF protein kinase 2
SSH3 slingshot protein phosphatase 3
STK24 serine/threonine kinase 24
SUFU suppressor of fused homolog (Drosophila)
SYCE3 synaptonemal complex central element protein 3
SYNE2 spectrin repeat containing, nuclear envelope 2
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TCAF2 TRPM8 channel-associated factor 2
TENM2 teneurin transmembrane protein 2
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGM4 transglutaminase 4
TMEM105 transmembrane protein 105
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae)
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TSPAN10 tetraspanin 10
TTLL5 tubulin tyrosine ligase-like family member 5
UBR4 ubiquitin protein ligase E3 component n-recognin 4
USP3 ubiquitin specific peptidase 3
WDFY2 WD repeat and FYVE domain containing 2
WNT4 wingless-type MMTV integration site family, member 4
WWC2-AS2 WWC2 antisense RNA 2
ZAN zonadhesin (gene/pseudogene)
ZBTB4 zinc finger and BTB domain containing 4
ZNF385A zinc finger protein 385A
ZNF395 zinc finger protein 395
ZNF710 zinc finger protein 710

low expression

Symbol Name
CD164 CD164 molecule, sialomucin
CDC40 cell division cycle 40
LYRM2 LYR motif containing 2
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
RARS2 arginyl-tRNA synthetase 2, mitochondrial
TMEM167A transmembrane protein 167A