Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6484-01A-11R-1873-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

416 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6484-01A-11R-1873-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABHD12B abhydrolase domain containing 12B
ABHD16A abhydrolase domain containing 16A
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACOXL acyl-CoA oxidase-like
ACTBL2 actin, beta-like 2
ADA adenosine deaminase
ADAM7 ADAM metallopeptidase domain 7
ADAMDEC1 ADAM-like, decysin 1
ADD2 adducin 2 (beta)
ADGRE2 adhesion G protein-coupled receptor E2
AHR aryl hydrocarbon receptor
ALG1L2 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2
ALKBH3 alkB, alkylation repair homolog 3 (E. coli)
ALOX5 arachidonate 5-lipoxygenase
ALPL alkaline phosphatase, liver/bone/kidney
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APIP APAF1 interacting protein
APOE apolipoprotein E
APOL1 apolipoprotein L, 1
APOL6 apolipoprotein L, 6
ARPIN actin-related protein 2/3 complex inhibitor
ARR3 arrestin 3, retinal (X-arrestin)
ARSB arylsulfatase B
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
AVPR1B arginine vasopressin receptor 1B
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
BTN3A2 butyrophilin, subfamily 3, member A2
BTN3A3 butyrophilin, subfamily 3, member A3
C11ORF74 chromosome 11 open reading frame 74
C15ORF39 chromosome 15 open reading frame 39
C17ORF77 chromosome 17 open reading frame 77
C1ORF111 chromosome 1 open reading frame 111
C1ORF186 chromosome 1 open reading frame 186
C1QC complement component 1, q subcomponent, C chain
C2 complement component 2
C20ORF202 chromosome 20 open reading frame 202
CAPRIN1 cell cycle associated protein 1
CAT catalase
CATSPERB catsper channel auxiliary subunit beta
CBWD5 COBW domain containing 5
CC2D1A coiled-coil and C2 domain containing 1A
CCRL2 chemokine (C-C motif) receptor-like 2
CD14 CD14 molecule
CD163 CD163 molecule
CD4 CD4 molecule
CD44 CD44 molecule (Indian blood group)
CD59 CD59 molecule, complement regulatory protein
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD82 CD82 molecule
CD84 CD84 molecule
CECR1 cat eye syndrome chromosome region, candidate 1
CFB complement factor B
CHL1 cell adhesion molecule L1-like
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CIITA class II, major histocompatibility complex, transactivator
CKAP2 cytoskeleton associated protein 2
CLEC7A C-type lectin domain family 7, member A
CLIP1 CAP-GLY domain containing linker protein 1
CLMN calmin (calponin-like, transmembrane)
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COMMD9 COMM domain containing 9
CRTC3 CREB regulated transcription coactivator 3
CSF1R colony stimulating factor 1 receptor
CTSS cathepsin S
CXCR2 chemokine (C-X-C motif) receptor 2
CXORF21 chromosome X open reading frame 21
CYCS cytochrome c, somatic
CYFIP2 cytoplasmic FMR1 interacting protein 2
DDHD1 DDHD domain containing 1
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
DKFZP434K028 uncharacterized LOC26070
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DLEU2L deleted in lymphocytic leukemia 2-like
DNAJC14 DnaJ (Hsp40) homolog, subfamily C, member 14
DNASE1L3 deoxyribonuclease I-like 3
DNM2 dynamin 2
DOK3 docking protein 3
DPP8 dipeptidyl-peptidase 8
DPYD dihydropyrimidine dehydrogenase
DTWD2 DTW domain containing 2
DUOX2 dual oxidase 2
DUOXA2 dual oxidase maturation factor 2
DYTN dystrotelin
EDN1 endothelin 1
EEF2K eukaryotic elongation factor 2 kinase
EHF ets homologous factor
EMILIN2 elastin microfibril interfacer 2
ENG endoglin
EPAS1 endothelial PAS domain protein 1
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
EPHA5 EPH receptor A5
EPPK1 epiplakin 1
ERI2 ERI1 exoribonuclease family member 2
FABP12 fatty acid binding protein 12
FAM133A family with sequence similarity 133, member A
FAM151B family with sequence similarity 151, member B
FAM183B acyloxyacyl hydrolase (neutrophil)
FAM188B family with sequence similarity 188, member B
FAM20A family with sequence similarity 20, member A
FAM214A family with sequence similarity 214, member A
FAT2 FAT atypical cadherin 2
FBXL17 F-box and leucine-rich repeat protein 17
FBXO3 F-box protein 3
FCRLB Fc receptor-like B
FDPSP2 farnesyl diphosphate synthase pseudogene 2
FEM1B fem-1 homolog b (C. elegans)
FERMT1 fermitin family member 1
FFAR4 free fatty acid receptor 4
FITM2 fat storage-inducing transmembrane protein 2
FJX1 four jointed box 1 (Drosophila)
FOXK1 forkhead box K1
FOXN3 forkhead box N3
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GALM galactose mutarotase (aldose 1-epimerase)
GDPGP1 GDP-D-glucose phosphorylase 1
GGCX gamma-glutamyl carboxylase
GLDN gliomedin
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
GMIP GEM interacting protein
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPM6B glycoprotein M6B
GPR150 G protein-coupled receptor 150
GPR158 G protein-coupled receptor 158
GPR20 G protein-coupled receptor 20
GPR31 G protein-coupled receptor 31
GPR4 G protein-coupled receptor 4
GPR65 G protein-coupled receptor 65
GRAMD1B GRAM domain containing 1B
GRID1 glutamate receptor, ionotropic, delta 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GSG1 germ cell associated 1
GTF2A2 general transcription factor IIA, 2, 12kDa
GUCY2GP guanylate cyclase 2G, pseudogene
HAVCR2 hepatitis A virus cellular receptor 2
HDAC7 histone deacetylase 7
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
HEXB hexosaminidase B (beta polypeptide)
HINT3 histidine triad nucleotide binding protein 3
HIPK3 homeodomain interacting protein kinase 3
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DPB2 major histocompatibility complex, class II, DP beta 2 (pseudogene)
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HRK harakiri, BCL2 interacting protein
HTRA4 HtrA serine peptidase 4
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
IFI30 interferon, gamma-inducible protein 30
IFNA21 interferon, alpha 21
IL10RA interleukin 10 receptor, alpha
IL21 interleukin 21
IL26 interleukin 26
IL7 interleukin 7
ILVBL ilvB (bacterial acetolactate synthase)-like
IPCEF1 interaction protein for cytohesin exchange factors 1
IRF1 interferon regulatory factor 1
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JADE2 jade family PHD finger 2
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCNIP3 Kv channel interacting protein 3, calsenilin
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCTD12 potassium channel tetramerization domain containing 12
KLF13 Kruppel-like factor 13
KLK13 kallikrein-related peptidase 13
KYNU kynureninase
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAP3 leucine aminopeptidase 3
LAPTM5 lysosomal protein transmembrane 5
LARS leucyl-tRNA synthetase
LAX1 lymphocyte transmembrane adaptor 1
LDLRAD3 low density lipoprotein receptor class A domain containing 3
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LGMN legumain
LHFPL2 lipoma HMGIC fusion partner-like 2
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LINC00114 long intergenic non-protein coding RNA 114
LINC00696 long intergenic non-protein coding RNA 696
LINC01588 long intergenic non-protein coding RNA 1588
LINS lines homolog (Drosophila)
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC100129935 lectin, galactoside-binding, soluble, 14 pseudogene
LOC100190986 uncharacterized LOC100190986
LPAR4 lysophosphatidic acid receptor 4
LPAR6 lysophosphatidic acid receptor 6
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
LRRK1 leucine-rich repeat kinase 1
LY96 lymphocyte antigen 96
LYN LYN proto-oncogene, Src family tyrosine kinase
MAGEC2 melanoma antigen family C2
MAN2B1 mannosidase, alpha, class 2B, member 1
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MARCO macrophage receptor with collagenous structure
MAST3 microtubule associated serine/threonine kinase 3
MAST4 microtubule associated serine/threonine kinase family member 4
MBLAC2 metallo-beta-lactamase domain containing 2
MCTP2 multiple C2 domains, transmembrane 2
MDFIC MyoD family inhibitor domain containing
MEGF11 multiple EGF-like-domains 11
MEP1B meprin A, beta
MIEF1 mitochondrial elongation factor 1
MKX mohawk homeobox
MNDA myeloid cell nuclear differentiation antigen
MRGPRX3 MAS-related GPR, member X3
MSR1 macrophage scavenger receptor 1
MUC1 mucin 1, cell surface associated
MUC4 mucin 4, cell surface associated
MYO1F myosin IF
NAT10 N-acetyltransferase 10 (GCN5-related)
NAT8B N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)
NCK2 NCK adaptor protein 2
NCKAP1L NCK-associated protein 1-like
NCOA7 nuclear receptor coactivator 7
NFAM1 NFAT activating protein with ITAM motif 1
NIPAL2 NIPA-like domain containing 2
NLRC4 NLR family, CARD domain containing 4
NOTCH3 notch 3
NRROS negative regulator of reactive oxygen species
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OCA2 oculocutaneous albinism II
OLFM4 olfactomedin 4
OMD osteomodulin
OR10A2 olfactory receptor, family 10, subfamily A, member 2
OR10A4 olfactory receptor, family 10, subfamily A, member 4
OR13D1 olfactory receptor, family 13, subfamily D, member 1
OR14C36 olfactory receptor, family 14, subfamily C, member 36
OR52K2 olfactory receptor, family 52, subfamily K, member 2
OSCAR osteoclast associated, immunoglobulin-like receptor
OTOP3 otopetrin 3
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PCDHB4 protocadherin beta 4
PCDHB6 protocadherin beta 6
PCDHB8 protocadherin beta 8
PCDHGA9 protocadherin gamma subfamily A, 9
PCP4L1 Purkinje cell protein 4 like 1
PDHX pyruvate dehydrogenase complex, component X
PEAK1 pseudopodium-enriched atypical kinase 1
PEX16 peroxisomal biogenesis factor 16
PHF7 PHD finger protein 7
PIAS1 protein inhibitor of activated STAT, 1
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PILRA paired immunoglobin-like type 2 receptor alpha
PLK2 polo-like kinase 2
PML promyelocytic leukemia
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD)
POU6F2 POU class 6 homeobox 2
PPAP2A phosphatidic acid phosphatase type 2A
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPP6R1 protein phosphatase 6, regulatory subunit 1
PRAM1 PML-RARA regulated adaptor molecule 1
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRICKLE4 prickle homolog 4 (Drosophila)
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PROSER1 proline and serine rich 1
PRSS35 protease, serine, 35
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RAB8B RAB8B, member RAS oncogene family
RAG1 recombination activating gene 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RDH10 retinol dehydrogenase 10 (all-trans)
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RIN3 Ras and Rab interactor 3
RMDN3 regulator of microtubule dynamics 3
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNF113B ring finger protein 113B
RP1L1 retinitis pigmentosa 1-like 1
RRN3P3 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 3
RYR2 ryanodine receptor 2 (cardiac)
S100A7A S100 calcium binding protein A7A
SAMD1 sterile alpha motif domain containing 1
SAMHD1 SAM domain and HD domain 1
SDS serine dehydratase
SEC16B SEC16 homolog B (S. cerevisiae)
SEC24A SEC24 family member A
SEPT7P9 septin 7 pseudogene 9
SERPINA13P serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 13, pseudogene
SERTAD4 SERTA domain containing 4
SETD9 SET domain containing 9
SETDB2 SET domain, bifurcated 2
SH3RF3 SH3 domain containing ring finger 3
SIDT1 SID1 transmembrane family, member 1
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIGLEC14 sialic acid binding Ig-like lectin 14
SIGLEC9 sialic acid binding Ig-like lectin 9
SIRPB1 signal-regulatory protein beta 1
SIRPB2 signal-regulatory protein beta 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC46A3 solute carrier family 46, member 3
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMAD3 SMAD family member 3
SMAD6 SMAD family member 6
SNX30 sorting nexin family member 30
SOD2 superoxide dismutase 2, mitochondrial
SOWAHD sosondowah ankyrin repeat domain family member D
SOX7 SRY (sex determining region Y)-box 7
SP140 SP140 nuclear body protein
SPATA31A1 SPATA31 subfamily A, member 1
SPATA31A6 SPATA31 subfamily A, member 6
SPI1 Spi-1 proto-oncogene
SPINT3 serine peptidase inhibitor, Kunitz type, 3
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
ST7-OT4 ST7 overlapping transcript 4
STOML1 stomatin (EPB72)-like 1
STRA6 stimulated by retinoic acid 6
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAGAP T-cell activation RhoGTPase activating protein
TAL1 T-cell acute lymphocytic leukemia 1
TAOK3 TAO kinase 3
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAS2R43 taste receptor, type 2, member 43
TBXAS1 thromboxane A synthase 1 (platelet)
TFEC transcription factor EC
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THBD thrombomodulin
THEM6 thioesterase superfamily member 6
THUMPD1 THUMP domain containing 1
TICRR TOPBP1-interacting checkpoint and replication regulator
TLR8 toll-like receptor 8
TMEM159 transmembrane protein 159
TMEM171 transmembrane protein 171
TMEM51-AS1 TMEM51 antisense RNA 1
TMEM87B transmembrane protein 87B
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TPH2 tryptophan hydroxylase 2
TPK1 thiamin pyrophosphokinase 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRHDE thyrotropin-releasing hormone degrading enzyme
TRIL TLR4 interactor with leucine-rich repeats
TRIM44 tripartite motif containing 44
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TTC17 tetratricopeptide repeat domain 17
TTLL13P tubulin tyrosine ligase-like family member 13, pseudogene
TXNDC11 thioredoxin domain containing 11
TXNDC2 thioredoxin domain containing 2 (spermatozoa)
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
TXNIP thioredoxin interacting protein
TYROBP TYRO protein tyrosine kinase binding protein
USP3 ubiquitin specific peptidase 3
UTS2 urotensin 2
VAMP5 vesicle-associated membrane protein 5
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae)
VSIG4 V-set and immunoglobulin domain containing 4
WDR72 WD repeat domain 72
WIZ widely interspaced zinc finger motifs
XDH xanthine dehydrogenase
XKR6 XK, Kell blood group complex subunit-related family, member 6
ZC3H12A zinc finger CCCH-type containing 12A
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZEB2 zinc finger E-box binding homeobox 2
ZNF101 zinc finger protein 101
ZNF121 zinc finger protein 121
ZNF136 zinc finger protein 136
ZNF208 zinc finger protein 208
ZNF213 zinc finger protein 213
ZNF219 zinc finger protein 219
ZNF257 zinc finger protein 257
ZNF317 zinc finger protein 317
ZNF320 zinc finger protein 320
ZNF391 zinc finger protein 391
ZNF43 zinc finger protein 43
ZNF433 zinc finger protein 433
ZNF440 zinc finger protein 440
ZNF486 zinc finger protein 486
ZNF490 zinc finger protein 490
ZNF506 zinc finger protein 506
ZNF551 zinc finger protein 551
ZNF552 zinc finger protein 552
ZNF585B zinc finger protein 585B
ZNF619 zinc finger protein 619
ZNF679 zinc finger protein 679
ZNF682 zinc finger protein 682
ZNF702P zinc finger protein 702, pseudogene
ZNF710 zinc finger protein 710
ZNF716 zinc finger protein 716
ZNF737 zinc finger protein 737
ZNF790 zinc finger protein 790
ZNF791 zinc finger protein 791
ZNF816 zinc finger protein 816
ZNF826P zinc finger protein 826, pseudogene
ZNF836 zinc finger protein 836
ZNF85 zinc finger protein 85
ZNF93 zinc finger protein 93
ZNF98 zinc finger protein 98
ZNFX1 zinc finger, NFX1-type containing 1
ZSCAN4 zinc finger and SCAN domain containing 4
ZSCAN5B zinc finger and SCAN domain containing 5B

low expression

Symbol Name
FIP1L1 factor interacting with PAPOLA and CPSF1
GRSF1 G-rich RNA sequence binding factor 1
METAP1 methionyl aminopeptidase 1