Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6471-01A-11R-1873-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

374 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6471-01A-11R-1873-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ABLIM1 actin binding LIM protein 1
ADAM10 ADAM metallopeptidase domain 10
ADAMTSL3 ADAMTS-like 3
AFF4 AF4/FMR2 family, member 4
AGFG1 ArfGAP with FG repeats 1
AGGF1 angiogenic factor with G patch and FHA domains 1
AKR1B15 aldo-keto reductase family 1, member B15
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKHD1 ankyrin repeat and KH domain containing 1
ANKRD13C ankyrin repeat domain 13C
ANKRD32 ankyrin repeat domain 32
ANKRD34B ankyrin repeat domain 34B
AP3B1 adaptor-related protein complex 3, beta 1 subunit
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APC adenomatous polyposis coli
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARID1B AT rich interactive domain 1B (SWI1-like)
ARID5B AT rich interactive domain 5B (MRF1-like)
ATAD2 ATPase family, AAA domain containing 2
ATAD5 ATPase family, AAA domain containing 5
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
ATXN7 ataxin 7
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
BLNK B-cell linker
BRCA2 breast cancer 2, early onset
BRD1 bromodomain containing 1
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C17ORF53 chromosome 17 open reading frame 53
C1ORF111 chromosome 1 open reading frame 111
C22ORF23 chromosome 22 open reading frame 23
C3ORF38 chromosome 3 open reading frame 38
C6ORF10 chromosome 6 open reading frame 10
C6ORF106 chromosome 6 open reading frame 106
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CARD6 caspase recruitment domain family, member 6
CASC5 cancer susceptibility candidate 5
CCDC69 coiled-coil domain containing 69
CCNE2 cyclin E2
CCNJL cyclin J-like
CCR4 chemokine (C-C motif) receptor 4
CD96 CD96 molecule
CDC14C cell division cycle 14C
CDC23 cell division cycle 23
CDC25A cell division cycle 25A
CDC25C cell division cycle 25C
CDC42SE2 CDC42 small effector 2
CENPQ centromere protein Q
CENPU centromere protein U
CEP128 centrosomal protein 128kDa
CFHR1 complement factor H-related 1
CHD1 chromodomain helicase DNA binding protein 1
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
CLCN3 chloride channel, voltage-sensitive 3
CLOCK clock circadian regulator
CNOT1 CCR4-NOT transcription complex, subunit 1
CNOT6 CCR4-NOT transcription complex, subunit 6
CNOT6L CCR4-NOT transcription complex, subunit 6-like
CNOT8 CCR4-NOT transcription complex, subunit 8
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CRYBA2 crystallin, beta A2
CSNK1A1 casein kinase 1, alpha 1
CSNK1A1L casein kinase 1, alpha 1-like
CSNK1A1P1 casein kinase 1, alpha 1 pseudogene 1
CSNK1G3 casein kinase 1, gamma 3
CST7 cystatin F (leukocystatin)
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
DCP2 decapping mRNA 2
DCTN4 dynactin 4 (p62)
DDIAS DNA damage-induced apoptosis suppressor
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND4C DENN/MADD domain containing 4C
DENND6A DENN/MADD domain containing 6A
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHFR dihydrofolate reductase
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DMRTA1 DMRT-like family A1
DMXL1 Dmx-like 1
DSC2 desmocollin 2
DSG3 desmoglein 3
E2F2 E2F transcription factor 2
E2F8 E2F transcription factor 8
EAF1 ELL associated factor 1
EFNA5 ephrin-A5
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
ELF1 E74-like factor 1 (ets domain transcription factor)
ELL2 elongation factor, RNA polymerase II, 2
EMP2 epithelial membrane protein 2
ENAH enabled homolog (Drosophila)
EP300 E1A binding protein p300
EPPK1 epiplakin 1
ERBB2IP erbb2 interacting protein
ERC1 ELKS/RAB6-interacting/CAST family member 1
ETF1 eukaryotic translation termination factor 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EXOC4 exocyst complex component 4
FAF2 Fas associated factor family member 2
FAM105A family with sequence similarity 105, member A
FAM114A2 family with sequence similarity 114, member A2
FAM129A family with sequence similarity 129, member A
FAM151B family with sequence similarity 151, member B
FAM174A family with sequence similarity 174, member A
FAM213A family with sequence similarity 213, member A
FAM45B family with sequence similarity 45, member A pseudogene
FAM63B family with sequence similarity 63, member B
FAM83G family with sequence similarity 83, member G
FANCD2 Fanconi anemia, complementation group D2
FANCD2OS FANCD2 opposite strand
FAT2 FAT atypical cadherin 2
FBXO38 F-box protein 38
FBXO8 F-box protein 8
FBXW11 F-box and WD repeat domain containing 11
FER fer (fps/fes related) tyrosine kinase
FERD3L Fer3-like bHLH transcription factor
FGD4 FYVE, RhoGEF and PH domain containing 4
FMR1-AS1 FMR1 antisense RNA 1
FRMD4B FERM domain containing 4B
FRYL FRY-like
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene)
GBX2 gastrulation brain homeobox 2
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GMEB1 glucocorticoid modulatory element binding protein 1
GNB5 guanine nucleotide binding protein (G protein), beta 5
GPA33 glycoprotein A33 (transmembrane)
GPATCH8 G patch domain containing 8
GPBP1 GC-rich promoter binding protein 1
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
GPR1 G protein-coupled receptor 1
GPR15 G protein-coupled receptor 15
GPRIN1 G protein regulated inducer of neurite outgrowth 1
GSG2 germ cell associated 2 (haspin)
GSTCD glutathione S-transferase, C-terminal domain containing
GTPBP1 GTP binding protein 1
GUCD1 guanylyl cyclase domain containing 1
H2AFY H2A histone family, member Y
HIST1H4F histone cluster 1, H4f
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGXB4 HMG box domain containing 4
HOMER1 homer scaffolding protein 1
HOMER2 homer scaffolding protein 2
HOOK1 hook microtubule-tethering protein 1
HSPA4L heat shock 70kDa protein 4-like
HTT huntingtin
IDI1 isopentenyl-diphosphate delta isomerase 1
IK IK cytokine, down-regulator of HLA II
IL9R interleukin 9 receptor
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IP6K1 inositol hexakisphosphate kinase 1
IPO11 importin 11
IRF2BPL interferon regulatory factor 2 binding protein-like
ITPKB inositol-trisphosphate 3-kinase B
JADE2 jade family PHD finger 2
JMY junction mediating and regulatory protein, p53 cofactor
KDM3B lysine (K)-specific demethylase 3B
KIAA1671 KIAA1671
KIF11 kinesin family member 11
KIF20B kinesin family member 20B
KIF2A kinesin heavy chain member 2A
KLF13 Kruppel-like factor 13
KREMEN1 kringle containing transmembrane protein 1
KRT6C keratin 6C, type II
KRT80 keratin 80, type II
LIN54 lin-54 DREAM MuvB core complex component
LOC100130264 uncharacterized LOC100130264
LRRN3 leucine rich repeat neuronal 3
LSM11 LSM11, U7 small nuclear RNA associated
LUZP6 leucine zipper protein 6
LYSMD3 LysM, putative peptidoglycan-binding, domain containing 3
MALT1 MALT1 paracaspase
MAML1 mastermind-like 1 (Drosophila)
MAN2A1 mannosidase, alpha, class 2A, member 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP4 microtubule-associated protein 4
MAPK1 mitogen-activated protein kinase 1
MAPK6 mitogen-activated protein kinase 6
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MAST4 microtubule associated serine/threonine kinase family member 4
MASTL microtubule associated serine/threonine kinase-like
MAT2B methionine adenosyltransferase II, beta
MCC mutated in colorectal cancers
MCM10 minichromosome maintenance complex component 10
MCM4 minichromosome maintenance complex component 4
MCM5 minichromosome maintenance complex component 5
MCM6 minichromosome maintenance complex component 6
MDFIC MyoD family inhibitor domain containing
MFAP3 microfibrillar-associated protein 3
MICALL1 MICAL-like 1
MIER1 mesoderm induction early response 1, transcriptional regulator
MIER3 mesoderm induction early response 1, family member 3
MKX mohawk homeobox
MORC3 MORC family CW-type zinc finger 3
MORC4 MORC family CW-type zinc finger 4
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
MPZL2 myelin protein zero-like 2
MTF2 metal response element binding transcription factor 2
MTMR3 myotubularin related protein 3
NBPF22P neuroblastoma breakpoint family, member 22, pseudogene
NBPF4 neuroblastoma breakpoint family, member 4
NBPF6 neuroblastoma breakpoint family, member 6
NCAPG2 non-SMC condensin II complex, subunit G2
NCOA2 nuclear receptor coactivator 2
NDFIP1 Nedd4 family interacting protein 1
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NEURL1B neuralized E3 ubiquitin protein ligase 1B
NIPAL2 NIPA-like domain containing 2
NIPBL Nipped-B homolog (Drosophila)
NLGN4X neuroligin 4, X-linked
NPAT nuclear protein, ataxia-telangiectasia locus
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NSD1 nuclear receptor binding SET domain protein 1
NUP155 nucleoporin 155kDa
NUP50 nucleoporin 50kDa
OCLN occludin
OR10H5 olfactory receptor, family 10, subfamily H, member 5
OSBPL10 oxysterol binding protein-like 10
OTUD7A OTU deubiquitinase 7A
PBRM1 polybromo 1
PCYOX1L prenylcysteine oxidase 1 like
PDX1 pancreatic and duodenal homeobox 1
PERP PERP, TP53 apoptosis effector
PHAX phosphorylated adaptor for RNA export
PI4K2B phosphatidylinositol 4-kinase type 2 beta
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PITPNM3 PITPNM family member 3
PITX1 paired-like homeodomain 1
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PKP1 plakophilin 1
PLK4 polo-like kinase 4
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRDM4 PR domain containing 4
PRR14L proline rich 14-like
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PURA purine-rich element binding protein A
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
PWWP2A PWWP domain containing 2A
QRICH1 glutamine-rich 1
RAB5A RAB5A, member RAS oncogene family
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAD18 RAD18 E3 ubiquitin protein ligase
RAD51 RAD51 recombinase
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RB1 retinoblastoma 1
RBM22 RNA binding motif protein 22
RBM27 RNA binding motif protein 27
RCOR1 REST corepressor 1
RET ret proto-oncogene
RIMS3 regulating synaptic membrane exocytosis 3
RNF11 ring finger protein 11
RNF145 ring finger protein 145
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
RTKN2 rhotekin 2
SASH1 SAM and SH3 domain containing 1
SASS6 spindle assembly 6 homolog (C. elegans)
SBF1 SET binding factor 1
SBF1P1 SET binding factor 1 pseudogene 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEPT8 septin 8
SERINC5 serine incorporator 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SFMBT1 Scm-like with four mbt domains 1
SFXN5 sideroflexin 5
SGOL1 shugoshin-like 1 (S. pombe)
SH3RF2 SH3 domain containing ring finger 2
SHCBP1 SHC SH2-domain binding protein 1
SIK3 SIK family kinase 3
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SLAIN2 SLAIN motif family, member 2
SLC22A23 solute carrier family 22, member 23
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC38A9 solute carrier family 38, member 9
SLMAP sarcolemma associated protein
SLU7 SLU7 splicing factor homolog (S. cerevisiae)
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMIM14 small integral membrane protein 14
SMIM15 small integral membrane protein 15
SNIP1 Smad nuclear interacting protein 1
SNRK SNF related kinase
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SNX2 sorting nexin 2
SNX24 sorting nexin 24
SREBF2 sterol regulatory element binding transcription factor 2
SREK1IP1 SREK1-interacting protein 1
STXBP5 syntaxin binding protein 5 (tomosyn)
SUFU suppressor of fused homolog (Drosophila)
SYNJ1 synaptojanin 1
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
TCF19 transcription factor 19
TEF thyrotrophic embryonic factor
TFIP11 tuftelin interacting protein 11
THBD thrombomodulin
TICAM2 toll-like receptor adaptor molecule 2
TICRR TOPBP1-interacting checkpoint and replication regulator
TJP1 tight junction protein 1
TJP2 tight junction protein 2
TLE3 transducin-like enhancer of split 3
TM4SF20 transmembrane 4 L six family member 20
TMEM167A transmembrane protein 167A
TMEM80 transmembrane protein 80
TMPRSS13 transmembrane protease, serine 13
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRAPPC10 trafficking protein particle complex 10
TRIM23 tripartite motif containing 23
TRIM6 tripartite motif containing 6
TRIOBP TRIO and F-actin binding protein
TRIP12 thyroid hormone receptor interactor 12
TRIP4 thyroid hormone receptor interactor 4
TSSK1B testis-specific serine kinase 1B
TTC37 tetratricopeptide repeat domain 37
TWF1 twinfilin actin binding protein 1
TYMP thymidine phosphorylase
UBE2B ubiquitin-conjugating enzyme E2B
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBTD2 ubiquitin domain containing 2
USP26 ubiquitin specific peptidase 26
USP32 ubiquitin specific peptidase 32
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
VWC2L von Willebrand factor C domain containing protein 2-like
WAC WW domain containing adaptor with coiled-coil
WDR37 WD repeat domain 37
WDR55 WD repeat domain 55
WNK1 WNK lysine deficient protein kinase 1
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
ZFYVE1 zinc finger, FYVE domain containing 1
ZFYVE16 zinc finger, FYVE domain containing 16
ZMAT2 zinc finger, matrin-type 2
ZNF100 zinc finger protein 100
ZNF107 zinc finger protein 107
ZNF143 zinc finger protein 143
ZNF185 zinc finger protein 185 (LIM domain)
ZNF207 zinc finger protein 207
ZNF267 zinc finger protein 267
ZNF385B zinc finger protein 385B
ZNF430 zinc finger protein 430
ZNF503 zinc finger protein 503
ZNF681 zinc finger protein 681
ZNF714 zinc finger protein 714
ZNF770 zinc finger protein 770
ZNF831 zinc finger protein 831
ZNF876P zinc finger protein 876, pseudogene
ZNF878 zinc finger protein 878
ZNF92 zinc finger protein 92
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase
ZSWIM6 zinc finger, SWIM-type containing 6

low expression

Symbol Name
C17ORF70 chromosome 17 open reading frame 70
CSNK1D casein kinase 1, delta
EARS2 glutamyl-tRNA synthetase 2, mitochondrial
EXOC7 exocyst complex component 7
SMYD5 SMYD family member 5
TTC27 tetratricopeptide repeat domain 27
WDR45B WD repeat domain 45B