Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5247-01A-01R-2016-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

400 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5247-01A-01R-2016-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ADAM12 ADAM metallopeptidase domain 12
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADAMTSL4 ADAMTS-like 4
ADAP1 ArfGAP with dual PH domains 1
AK5 adenylate kinase 5
AKR1C2 aldo-keto reductase family 1, member C2
ALDOA aldolase A, fructose-bisphosphate
ALDOC aldolase C, fructose-bisphosphate
ALKBH5 AlkB family member 5, RNA demethylase
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANKRD37 ankyrin repeat domain 37
AQP6 aquaporin 6, kidney specific
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARL6IP6 ADP-ribosylation factor-like 6 interacting protein 6
ARMC10 armadillo repeat containing 10
ARMC9 armadillo repeat containing 9
ASPDH aspartate dehydrogenase domain containing
ATG9A autophagy related 9A
BAG2 BCL2-associated athanogene 2
BARX1 BARX homeobox 1
BCAP29 B-cell receptor-associated protein 29
BEST4 bestrophin 4
BMP8A bone morphogenetic protein 8a
BRI3 brain protein I3
BSND barttin CLCNK-type chloride channel accessory beta subunit
C14ORF37 chromosome 14 open reading frame 37
C15ORF32 chromosome 15 open reading frame 32
C1ORF74 chromosome 1 open reading frame 74
C3ORF67 chromosome 3 open reading frame 67
CALB1 calbindin 1, 28kDa
CAMK1D calcium/calmodulin-dependent protein kinase ID
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CBFB core-binding factor, beta subunit
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CCDC3 coiled-coil domain containing 3
CCR10 chemokine (C-C motif) receptor 10
CD109 CD109 molecule
CD164 CD164 molecule, sialomucin
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CDK15 cyclin-dependent kinase 15
CDR2L cerebellar degeneration-related protein 2-like
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CERK ceramide kinase
CHPF chondroitin polymerizing factor
CHSY3 chondroitin sulfate synthase 3
CLEC11A C-type lectin domain family 11, member A
CLEC18A C-type lectin domain family 18, member A
CLEC18B C-type lectin domain family 18, member B
CLEC18C C-type lectin domain family 18, member C
CLN5 ceroid-lipofuscinosis, neuronal 5
CNTN1 contactin 1
CNTN3 contactin 3 (plasmacytoma associated)
COG5 component of oligomeric golgi complex 5
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL5A1 collagen, type V, alpha 1
COL5A2 collagen, type V, alpha 2
COL5A3 collagen, type V, alpha 3
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
COL6A3 collagen, type VI, alpha 3
CORO1C coronin, actin binding protein, 1C
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like
CPA1 carboxypeptidase A1 (pancreatic)
CRTAP cartilage associated protein
CTBP2 C-terminal binding protein 2
CTHRC1 collagen triple helix repeat containing 1
CUL7 cullin 7
CYB5B cytochrome b5 type B (outer mitochondrial membrane)
DAAM2 dishevelled associated activator of morphogenesis 2
DACT1 dishevelled-binding antagonist of beta-catenin 1
DACT3 dishevelled-binding antagonist of beta-catenin 3
DARS aspartyl-tRNA synthetase
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCTD dCMP deaminase
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5
DERA deoxyribose-phosphate aldolase (putative)
DGKQ diacylglycerol kinase, theta 110kDa
DLD dihydrolipoamide dehydrogenase
DNAH10 dynein, axonemal, heavy chain 10
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
DSC3 desmocollin 3
DSG2 desmoglein 2
DSTN destrin (actin depolymerizing factor)
DUS4L dihydrouridine synthase 4-like (S. cerevisiae)
DUSP9 dual specificity phosphatase 9
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFCAB1 EF-hand calcium binding domain 1
EFCAB10 EF-hand calcium binding domain 10
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EMILIN1 elastin microfibril interfacer 1
EMX1 empty spiracles homeobox 1
ENO2 enolase 2 (gamma, neuronal)
ENOPH1 enolase-phosphatase 1
EPHB4 EPH receptor B4
ESPNL espin-like
FAM134A family with sequence similarity 134, member A
FAM159A family with sequence similarity 159, member A
FAM181A family with sequence similarity 181, member A
FAM184B family with sequence similarity 184, member B
FAM189A1 family with sequence similarity 189, member A1
FAM198B family with sequence similarity 198, member B
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
FAM210A family with sequence similarity 210, member A
FAM57A family with sequence similarity 57, member A
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FAT3 FAT atypical cadherin 3
FBRSL1 fibrosin-like 1
FBXL3 F-box and leucine-rich repeat protein 3
FBXO36 F-box protein 36
FERD3L Fer3-like bHLH transcription factor
FGF11 fibroblast growth factor 11
FGFBP2 fibroblast growth factor binding protein 2
FIBCD1 fibrinogen C domain containing 1
FKBP10 FK506 binding protein 10, 65 kDa
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLJ23867 uncharacterized protein FLJ23867
FOXH1 forkhead box H1
FOXO3 forkhead box O3
FYTTD1 forty-two-three domain containing 1
GALNS galactosamine (N-acetyl)-6-sulfatase
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GBX2 gastrulation brain homeobox 2
GCSH glycine cleavage system protein H (aminomethyl carrier)
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GLB1L galactosidase, beta 1-like
GLG1 golgi glycoprotein 1
GLIS3 GLIS family zinc finger 3
GLUD1 glutamate dehydrogenase 1
GLUD2 glutamate dehydrogenase 2
GML glycosylphosphatidylinositol anchored molecule like
GOLGA2P3Y golgin A2 pseudogene 3, Y-linked
GORASP2 golgi reassembly stacking protein 2, 55kDa
GPC1 glypican 1
GPR153 G protein-coupled receptor 153
GPR39 G protein-coupled receptor 39
GREM1 gremlin 1, DAN family BMP antagonist
GUCA2A guanylate cyclase activator 2A (guanylin)
H3F3B H3 histone, family 3B (H3.3B)
H3F3C H3 histone, family 3C
HBP1 HMG-box transcription factor 1
HCG4 HLA complex group 4 (non-protein coding)
HEPH hephaestin
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HS1BP3 HCLS1 binding protein 3
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HSDL1 hydroxysteroid dehydrogenase like 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSP90AB2P heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
HTRA1 HtrA serine peptidase 1
ICAM5 intercellular adhesion molecule 5, telencephalin
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
INSIG2 insulin induced gene 2
IRF6 interferon regulatory factor 6
ISLR immunoglobulin superfamily containing leucine-rich repeat
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KCMF1 potassium channel modulatory factor 1
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
KCTD12 potassium channel tetramerization domain containing 12
KCTD16 potassium channel tetramerization domain containing 16
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KDM1A lysine (K)-specific demethylase 1A
KHDC1L KH homology domain containing 1-like
KLHL36 kelch-like family member 36
KLK5 kallikrein-related peptidase 5
KSR2 kinase suppressor of ras 2
LAMP5 lysosomal-associated membrane protein family, member 5
LBH limb bud and heart development
LHX5 LIM homeobox 5
LHX8 LIM homeobox 8
LINC00521 long intergenic non-protein coding RNA 521
LMO7 LIM domain 7
LOC646214 p21 protein (Cdc42/Rac)-activated kinase 2 pseudogene
LOX lysyl oxidase
LRRC17 leucine rich repeat containing 17
LRRC73 leucine rich repeat containing 73
LRRN4 leucine rich repeat neuronal 4
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2
MATN3 matrilin 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MED28 mediator complex subunit 28
MEGF6 multiple EGF-like-domains 6
MEIS3 Meis homeobox 3
METTL11B methyltransferase like 11B
METTL21A methyltransferase like 21A
MFAP5 microfibrillar associated protein 5
MGC12916 uncharacterized protein MGC12916
MIB1 mindbomb E3 ubiquitin protein ligase 1
MLF1 myeloid leukemia factor 1
MMP11 matrix metallopeptidase 11
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MOSPD3 motile sperm domain containing 3
MRC2 mannose receptor, C type 2
MRGPRF MAS-related GPR, member F
MRPL14 mitochondrial ribosomal protein L14
MRPL2 mitochondrial ribosomal protein L2
MT1L metallothionein 1L (gene/pseudogene)
MTMR2 myotubularin related protein 2
MXI1 MAX interactor 1, dimerization protein
MXRA7 matrix-remodelling associated 7
MYH16 myosin, heavy chain 16 pseudogene
MYO1C myosin IC
MYO1D myosin ID
MYO3B myosin IIIB
MZT1 mitotic spindle organizing protein 1
NACAD NAC alpha domain containing
NDFIP2 Nedd4 family interacting protein 2
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NEGR1 neuronal growth regulator 1
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1
NEU1 sialidase 1 (lysosomal sialidase)
NHEJ1 nonhomologous end-joining factor 1
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1
NOBOX NOBOX oogenesis homeobox
NPNT nephronectin
NPR1 natriuretic peptide receptor 1
NR5A1 nuclear receptor subfamily 5, group A, member 1
NRCAM neuronal cell adhesion molecule
NT5DC2 5'-nucleotidase domain containing 2
NTM neurotrimin
NXN nucleoredoxin
OR6B2 olfactory receptor, family 6, subfamily B, member 2
OR6B3 olfactory receptor, family 6, subfamily B, member 3
P3H3 prolyl 3-hydroxylase 3
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
P4HA3 prolyl 4-hydroxylase, alpha polypeptide III
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAQR3 progestin and adipoQ receptor family member III
PCDHGA9 protocadherin gamma subfamily A, 9
PCDHGC3 protocadherin gamma subfamily C, 3
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PCSK9 proprotein convertase subtilisin/kexin type 9
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDIA6 protein disulfide isomerase family A, member 6
PDZD7 PDZ domain containing 7
PDZK1 PDZ domain containing 1
PEG10 paternally expressed 10
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PFN2 profilin 2
PGAM1 phosphoglycerate mutase 1 (brain)
PGM3 phosphoglucomutase 3
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PITPNM3 PITPNM family member 3
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PNPLA8 patatin-like phospholipase domain containing 8
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
POSTN periostin, osteoblast specific factor
PPAPDC1A phosphatidic acid phosphatase type 2 domain containing 1A
PPM1J protein phosphatase, Mg2+/Mn2+ dependent, 1J
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C
PPP1R1C protein phosphatase 1, regulatory (inhibitor) subunit 1C
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PPP1R3G protein phosphatase 1, regulatory subunit 3G
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PRSS8 protease, serine, 8
PSG11 pregnancy specific beta-1-glycoprotein 11
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTK7 protein tyrosine kinase 7 (inactive)
PTRF polymerase I and transcript release factor
PUS7 pseudouridylate synthase 7 (putative)
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB1A RAB1A, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAN RAN, member RAS oncogene family
RAP2B RAP2B, member of RAS oncogene family
RARS2 arginyl-tRNA synthetase 2, mitochondrial
RGS4 regulator of G-protein signaling 4
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RNF219 ring finger protein 219
SCARB1 scavenger receptor class B, member 1
SCD5 stearoyl-CoA desaturase 5
SDC1 syndecan 1
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SEPT11 septin 11
SERP1 stress-associated endoplasmic reticulum protein 1
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SFTA1P surfactant associated 1, pseudogene
SGCE sarcoglycan, epsilon
SH3D19 SH3 domain containing 19
SH3GL1 SH3-domain GRB2-like 1
SHANK1 SH3 and multiple ankyrin repeat domains 1
SIAH2 siah E3 ubiquitin protein ligase 2
SLAMF9 SLAM family member 9
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A6OS solute carrier family 7, member 6 opposite strand
SNX25 sorting nexin 25
SOCS5 suppressor of cytokine signaling 5
SOX15 SRY (sex determining region Y)-box 15
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative)
SRPK2 SRSF protein kinase 2
SRPX2 sushi-repeat containing protein, X-linked 2
SSC5D scavenger receptor cysteine rich family, 5 domains
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
SULF1 sulfatase 1
SUMO4 small ubiquitin-like modifier 4
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SYNDIG1 synapse differentiation inducing 1
SYPL1 synaptophysin-like 1
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TAGLN transgelin
TBC1D4 TBC1 domain family, member 4
TBX6 T-box 6
TCF4 transcription factor 4
TET1 tet methylcytosine dioxygenase 1
TEX2 testis expressed 2
TFPI2 tissue factor pathway inhibitor 2
TFR2 transferrin receptor 2
TGFB1 transforming growth factor, beta 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THAP5 THAP domain containing 5
THBS2 thrombospondin 2
THY1 Thy-1 cell surface antigen
TIMP2 TIMP metallopeptidase inhibitor 2
TLL2 tolloid-like 2
TM4SF1 transmembrane 4 L six family member 1
TM6SF2 transmembrane 6 superfamily member 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMC7 transmembrane channel-like 7
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM101 transmembrane protein 101
TMEM117 transmembrane protein 117
TMEM123 transmembrane protein 123
TMEM204 transmembrane protein 204
TMEM223 transmembrane protein 223
TMEM249 transmembrane protein 249
TMEM26 transmembrane protein 26
TMIE transmembrane inner ear
TMTC3 transmembrane and tetratricopeptide repeat containing 3
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TP53TG5 TP53 target 5
TPPP3 tubulin polymerization-promoting protein family member 3
TPRXL tetra-peptide repeat homeobox-like
TRAM2 translocation associated membrane protein 2
TREM2 triggering receptor expressed on myeloid cells 2
TSGA10IP testis specific, 10 interacting protein
TSPAN9 tetraspanin 9
TTLL12 tubulin tyrosine ligase-like family member 12
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
UFSP2 UFM1-specific peptidase 2
UNC119B unc-119 homolog B (C. elegans)
UNC5B unc-5 homolog B (C. elegans)
UPK3BL uroplakin 3B-like
VCAN versican
VEGFA vascular endothelial growth factor A
WLS wntless Wnt ligand secretion mediator
WNT10A wingless-type MMTV integration site family, member 10A
WNT2 wingless-type MMTV integration site family member 2
WNT3A wingless-type MMTV integration site family, member 3A
XXYLT1 xyloside xylosyltransferase 1
YAP1 Yes-associated protein 1
ZNF114 zinc finger protein 114
ZNF705D zinc finger protein 705D
ZNF883 zinc finger protein 883

low expression

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
C17ORF85 chromosome 17 open reading frame 85
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GOLGA1 golgin A1
SECISBP2 SECIS binding protein 2
SLC35A4 solute carrier family 35, member A4
ZNF638 zinc finger protein 638
ZSWIM1 zinc finger, SWIM-type containing 1