Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4C9-01A-11R-A24Z-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

398 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4C9-01A-11R-A24Z-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACP1 acid phosphatase 1, soluble
ACSS1 acyl-CoA synthetase short-chain family member 1
ADAMTSL5 ADAMTS-like 5
ADCK2 aarF domain containing kinase 2
ADCY3 adenylate cyclase 3
ADGRG5 adhesion G protein-coupled receptor G5
AFG3L2 AFG3-like AAA ATPase 2
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
AGK acylglycerol kinase
AKAP1 A kinase (PRKA) anchor protein 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANAPC7 anaphase promoting complex subunit 7
ANKRD20A4 ankyrin repeat domain 20 family, member A4
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6
ARHGAP27 Rho GTPase activating protein 27
ARHGEF35 Rho guanine nucleotide exchange factor (GEF) 35
ARID3C AT rich interactive domain 3C (BRIGHT-like)
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
AUP1 ancient ubiquitous protein 1
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
BCO1 beta-carotene oxygenase 1
BMP7 bone morphogenetic protein 7
BOK BCL2-related ovarian killer
BTBD2 BTB (POZ) domain containing 2
BZW2 basic leucine zipper and W2 domains 2
C10ORF91 chromosome 10 open reading frame 91
C15ORF56 chromosome 15 open reading frame 56
C15ORF59 chromosome 15 open reading frame 59
C1ORF110 chromosome 1 open reading frame 110
C1ORF131 chromosome 1 open reading frame 131
C1ORF198 chromosome 1 open reading frame 198
C1ORF226 chromosome 1 open reading frame 226
C1ORF229 chromosome 1 open reading frame 229
C7ORF43 chromosome 7 open reading frame 43
C7ORF49 chromosome 7 open reading frame 49
C9ORF173 chromosome 9 open reading frame 173
CALML4 calmodulin-like 4
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CASKIN2 CASK interacting protein 2
CBX2 chromobox homolog 2
CBX8 chromobox homolog 8
CCBL2 cysteine conjugate-beta lyase 2
CCDC121 coiled-coil domain containing 121
CCDC137 coiled-coil domain containing 137
CCDC142 coiled-coil domain containing 142
CCDC185 coiled-coil domain containing 185
CCDC25 coiled-coil domain containing 25
CCDC54 coiled-coil domain containing 54
CCT6P1 chaperonin containing TCP1, subunit 6 (zeta) pseudogene 1
CDAN1 codanin 1
CDRT15 CMT1A duplicated region transcript 15
CEACAM16 carcinoembryonic antigen-related cell adhesion molecule 16
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CEP76 centrosomal protein 76kDa
CFHR3 complement factor H-related 3
CFHR4 complement factor H-related 4
CHMP3 charged multivesicular body protein 3
CNGA1 cyclic nucleotide gated channel alpha 1
CPNE7 copine VII
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa
CRCP CGRP receptor component
CROCC ciliary rootlet coiled-coil, rootletin
CSK c-src tyrosine kinase
CST8 cystatin 8 (cystatin-related epididymal specific)
CYB561 cytochrome b561
CYTH1 cytohesin 1
DAP3 death associated protein 3
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DEDD death effector domain containing
DGKE diacylglycerol kinase, epsilon 64kDa
DGKQ diacylglycerol kinase, theta 110kDa
DHODH dihydroorotate dehydrogenase (quinone)
DMRT3 doublesex and mab-3 related transcription factor 3
DNA2 DNA replication helicase/nuclease 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOLPP1 dolichyldiphosphatase 1
DQX1 DEAQ box RNA-dependent ATPase 1
DRAM2 DNA-damage regulated autophagy modulator 2
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
E2F6 E2F transcription factor 6
EDAR ectodysplasin A receptor
EFCAB3 EF-hand calcium binding domain 3
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPHA1 EPH receptor A1
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2
ESPNL espin-like
ETNK2 ethanolamine kinase 2
EVC2 Ellis van Creveld syndrome 2
EVPLL envoplakin-like
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FADS6 fatty acid desaturase 6
FAM109B family with sequence similarity 109, member B
FAM157A family with sequence similarity 157, member A
FAM157B family with sequence similarity 157, member B
FAM160B2 family with sequence similarity 160, member B2
FAM73B family with sequence similarity 73, member B
FBXL19 F-box and leucine-rich repeat protein 19
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FLJ42627 uncharacterized LOC645644
FRAT2 frequently rearranged in advanced T-cell lymphomas 2
FZD10 frizzled class receptor 10
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GAS8 growth arrest-specific 8
GBGT1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
GCFC2 GC-rich sequence DNA-binding factor 2
GDF3 growth differentiation factor 3
GEN1 GEN1 Holliday junction 5' flap endonuclease
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GGCT gamma-glutamylcyclotransferase
GGT3P gamma-glutamyltransferase 3 pseudogene
GIGYF1 GRB10 interacting GYF protein 1
GIPC2 GIPC PDZ domain containing family, member 2
GLB1L galactosidase, beta 1-like
GPR143 G protein-coupled receptor 143
GPR78 G protein-coupled receptor 78
GRAMD4 GRAM domain containing 4
GRK7 G protein-coupled receptor kinase 7
GRTP1 growth hormone regulated TBC protein 1
GSTA3 glutathione S-transferase alpha 3
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa
GTF2IRD1 GTF2I repeat domain containing 1
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
HCAR1 hydroxycarboxylic acid receptor 1
HDAC10 histone deacetylase 10
HEATR5B HEAT repeat containing 5B
HHAT hedgehog acyltransferase
HILPDA hypoxia inducible lipid droplet-associated
HMX2 H6 family homeobox 2
HOXA2 homeobox A2
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
HSF4 heat shock transcription factor 4
HUS1 HUS1 checkpoint homolog (S. pombe)
HYAL1 hyaluronoglucosaminidase 1
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL17C interleukin 17C
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
INTS10 integrator complex subunit 10
IRF5 interferon regulatory factor 5
ISM2 isthmin 2
ITPRIPL1 inositol 1,4,5-trisphosphate receptor interacting protein-like 1
KCNK10 potassium channel, two pore domain subfamily K, member 10
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KCP kielin/chordin-like protein
KCTD3 potassium channel tetramerization domain containing 3
KIAA0195 KIAA0195
KPNA7 karyopherin alpha 7 (importin alpha 8)
KRTAP5-9 keratin associated protein 5-9
KRTCAP3 keratinocyte associated protein 3
LEFTY1 left-right determination factor 1
LEMD1 LEM domain containing 1
LIMK1 LIM domain kinase 1
LINC00235 long intergenic non-protein coding RNA 235
LINC00264 long intergenic non-protein coding RNA 264
LINC00312 long intergenic non-protein coding RNA 312
LOC100132215 uncharacterized LOC100132215
LOC100132287 uncharacterized LOC100132287
LOC100133331 uncharacterized LOC100133331
LOC100134868 uncharacterized LOC100134868
LOC148709 actin pseudogene
LOC650293 seven transmembrane helix receptor
LOC730668 dynein heavy chain -like pseudogene
LOC90784 uncharacterized LOC90784
LPAR6 lysophosphatidic acid receptor 6
LRFN2 leucine rich repeat and fibronectin type III domain containing 2
LRIT2 leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1
LZTS2 leucine zipper, putative tumor suppressor 2
M1AP meiosis 1 associated protein
MAGEE2 melanoma antigen family E2
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MARC1 mitochondrial amidoxime reducing component 1
MATK megakaryocyte-associated tyrosine kinase
MBOAT2 membrane bound O-acyltransferase domain containing 2
MCEE methylmalonyl CoA epimerase
MERTK MER proto-oncogene, tyrosine kinase
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2
MFSD11 major facilitator superfamily domain containing 11
MFSD7 major facilitator superfamily domain containing 7
MIPOL1 mirror-image polydactyly 1
MKRN3 makorin ring finger protein 3
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
MPPE1 metallophosphoesterase 1
MRGPRX2 MAS-related GPR, member X2
MTA3 metastasis associated 1 family, member 3
MTIF2 mitochondrial translational initiation factor 2
MTRF1 mitochondrial translational release factor 1
MYO19 myosin XIX
MYO1H myosin IH
NAGLU N-acetylglucosaminidase, alpha
NAIF1 nuclear apoptosis inducing factor 1
NAT8B N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)
NDN necdin, melanoma antigen (MAGE) family member
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NELFCD negative elongation factor complex member C/D
NEUROG1 neurogenin 1
NINL ninein-like
NKX1-2 NK1 homeobox 2
NKX6-3 NK6 homeobox 3
NOBOX NOBOX oogenesis homeobox
NOL10 nucleolar protein 10
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOS3 nitric oxide synthase 3 (endothelial cell)
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NRBP1 nuclear receptor binding protein 1
NRTN neurturin
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUAK2 NUAK family, SNF1-like kinase, 2
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUP205 nucleoporin 205kDa
NUP85 nucleoporin 85kDa
ODF2 outer dense fiber of sperm tails 2
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OR13A1 olfactory receptor, family 13, subfamily A, member 1
OR3A3 olfactory receptor, family 3, subfamily A, member 3
ORAI3 ORAI calcium release-activated calcium modulator 3
OTOP2 otopetrin 2
OTOP3 otopetrin 3
OTX1 orthodenticle homeobox 1
PAPOLB poly(A) polymerase beta (testis specific)
PARP16 poly (ADP-ribose) polymerase family, member 16
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PCBP1 poly(rC) binding protein 1
PEX1 peroxisomal biogenesis factor 1
PGBD4 piggyBac transposable element derived 4
PGS1 phosphatidylglycerophosphate synthase 1
PHYHD1 phytanoyl-CoA dioxygenase domain containing 1
PI4KAP1 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
PIAS3 protein inhibitor of activated STAT, 3
PIGF phosphatidylinositol glycan anchor biosynthesis, class F
PIWIL2 piwi-like RNA-mediated gene silencing 2
PKD1L1 polycystic kidney disease 1 like 1
PKN3 protein kinase N3
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
PLXNA2 plexin A2
PNLDC1 poly(A)-specific ribonuclease (PARN)-like domain containing 1
PNPT1 polyribonucleotide nucleotidyltransferase 1
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
POR P450 (cytochrome) oxidoreductase
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PRAC1 prostate cancer susceptibility candidate 1
PRCD progressive rod-cone degeneration
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRORSD1P prolyl-tRNA synthetase associated domain containing 1, pseudogene
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1
PRR19 proline rich 19
PRRT1 proline-rich transmembrane protein 1
PRRT4 proline-rich transmembrane protein 4
PTCD1 pentatricopeptide repeat domain 1
PYCR1 pyrroline-5-carboxylate reductase 1
QRFPR pyroglutamylated RFamide peptide receptor
RAD51AP2 RAD51 associated protein 2
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RBM20 RNA binding motif protein 20
RBM28 RNA binding motif protein 28
RBPMS RNA binding protein with multiple splicing
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
REC8 REC8 meiotic recombination protein
REEP4 receptor accessory protein 4
REG1A regenerating islet-derived 1 alpha
RELL2 RELT-like 2
REPIN1 replication initiator 1
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RGMA repulsive guidance molecule family member a
RGS9BP regulator of G protein signaling 9 binding protein
RINL Ras and Rab interactor-like
RIPPLY2 ripply transcriptional repressor 2
RMDN3 regulator of microtubule dynamics 3
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPIA ribose 5-phosphate isomerase A
RPP25 ribonuclease P/MRP 25kDa subunit
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SAPCD2 suppressor APC domain containing 2
SCARA3 scavenger receptor class A, member 3
SCN2A sodium channel, voltage gated, type II alpha subunit
SCRIB scribbled planar cell polarity protein
SCRN3 secernin 3
SERHL2 serine hydrolase-like 2
SFXN2 sideroflexin 2
SFXN5 sideroflexin 5
SIRT7 sirtuin 7
SLC12A9 solute carrier family 12, member 9
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC22A20 solute carrier family 22, member 20
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC35F6 solute carrier family 35, member F6
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLC7A5P1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLFNL1 schlafen-like 1
SMAD3 SMAD family member 3
SMAD6 SMAD family member 6
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SMC6 structural maintenance of chromosomes 6
SMO smoothened, frizzled class receptor
SMYD5 SMYD family member 5
SNORA20 small nucleolar RNA, H/ACA box 20
SNORA5A small nucleolar RNA, H/ACA box 5A
SNX17 sorting nexin 17
SORD sorbitol dehydrogenase
SOX12 SRY (sex determining region Y)-box 12
SOX13 SRY (sex determining region Y)-box 13
SPATA25 spermatogenesis associated 25
SPIRE2 spire-type actin nucleation factor 2
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SPTBN5 spectrin, beta, non-erythrocytic 5
SQLE squalene epoxidase
SRRM3 serine/arginine repetitive matrix 3
ST7L suppression of tumorigenicity 7 like
STK40 serine/threonine kinase 40
STON1 stonin 1
SUOX sulfite oxidase
SUSD4 sushi domain containing 4
SYK spleen tyrosine kinase
SYNGR1 synaptogyrin 1
SYT15 synaptotagmin XV
SYT17 synaptotagmin XVII
TARBP1 TAR (HIV-1) RNA binding protein 1
TBKBP1 TBK1 binding protein 1
TBX6 T-box 6
TF transferrin
TFAMP1 transcription factor A, mitochondrial pseudogene 1
TFR2 transferrin receptor 2
TGM6 transglutaminase 6
THADA thyroid adenoma associated
THEM6 thioesterase superfamily member 6
THUMPD2 THUMP domain containing 2
TICRR TOPBP1-interacting checkpoint and replication regulator
TKFC triokinase/FMN cyclase
TMEM109 transmembrane protein 109
TMEM120A transmembrane protein 120A
TMEM209 transmembrane protein 209
TMEM37 transmembrane protein 37
TMTC4 transmembrane and tetratricopeptide repeat containing 4
TNPO3 transportin 3
TP53TG5 TP53 target 5
TRAPPC12 trafficking protein particle complex 12
TRIM17 tripartite motif containing 17
TRIM35 tripartite motif containing 35
TRIOBP TRIO and F-actin binding protein
TRIP6 thyroid hormone receptor interactor 6
TRMT61B tRNA methyltransferase 61B
TSPAN10 tetraspanin 10
TSSC1 tumor suppressing subtransferable candidate 1
TSSK6 testis-specific serine kinase 6
TTC27 tetratricopeptide repeat domain 27
TTLL12 tubulin tyrosine ligase-like family member 12
TUBD1 tubulin, delta 1
TYSND1 trypsin domain containing 1
UBXN2A UBX domain protein 2A
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
UPK1B uroplakin 1B
UPK3B uroplakin 3B
USH1G Usher syndrome 1G (autosomal recessive)
USP21 ubiquitin specific peptidase 21
USP39 ubiquitin specific peptidase 39
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1
VMAC vimentin-type intermediate filament associated coiled-coil protein
VSIG10 V-set and immunoglobulin domain containing 10
VSNL1 visinin-like 1
WDR92 WD repeat domain 92
WNK4 WNK lysine deficient protein kinase 4
WNT2B wingless-type MMTV integration site family, member 2B
XPA xeroderma pigmentosum, complementation group A
ZAN zonadhesin (gene/pseudogene)
ZBTB42 zinc finger and BTB domain containing 42
ZHX2 zinc fingers and homeoboxes 2
ZIC2 Zic family member 2
ZIC5 Zic family member 5
ZIM3 zinc finger, imprinted 3
ZNF212 zinc finger protein 212
ZNF252P-AS1 ZNF252P antisense RNA 1
ZNF273 zinc finger protein 273
ZNF395 zinc finger protein 395
ZNF645 zinc finger protein 645
ZNF655 zinc finger protein 655
ZNF767P zinc finger family member 767, pseudogene
ZNF792 zinc finger protein 792

low expression

Symbol Name
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
VAMP3 vesicle-associated membrane protein 3
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2