Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7068-01A-11R-2081-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

383 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7068-01A-11R-2081-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ACY3 aminoacylase 3
ADAM19 ADAM metallopeptidase domain 19
ADPRHL2 ADP-ribosylhydrolase like 2
AHR aryl hydrocarbon receptor
AIM2 absent in melanoma 2
AK3 adenylate kinase 3
AKAP5 A kinase (PRKA) anchor protein 5
ALKBH8 alkB, alkylation repair homolog 8 (E. coli)
ALPK1 alpha-kinase 1
APOBEC3D apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
APOL3 apolipoprotein L, 3
APOL4 apolipoprotein L, 4
APOL6 apolipoprotein L, 6
APTX aprataxin
ARID3C AT rich interactive domain 3C (BRIGHT-like)
ARRDC3 arrestin domain containing 3
ASS1 argininosuccinate synthase 1
BATF2 basic leucine zipper transcription factor, ATF-like 2
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BHLHE41 basic helix-loop-helix family, member e41
BIN3 bridging integrator 3
BTN3A3 butyrophilin, subfamily 3, member A3
C10ORF55 chromosome 10 open reading frame 55
C15ORF53 chromosome 15 open reading frame 53
C17ORF47 chromosome 17 open reading frame 47
C19ORF66 chromosome 19 open reading frame 66
C1ORF186 chromosome 1 open reading frame 186
C1ORF204 chromosome 1 open reading frame 204
C22ORF46 chromosome 22 open reading frame 46
C3ORF62 chromosome 3 open reading frame 62
C4ORF33 chromosome 4 open reading frame 33
C6ORF10 chromosome 6 open reading frame 10
C7ORF25 chromosome 7 open reading frame 25
C9ORF91 chromosome 9 open reading frame 91
CAAP1 caspase activity and apoptosis inhibitor 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CC2D1B coiled-coil and C2 domain containing 1B
CCAR2 cell cycle and apoptosis regulator 2
CCDC103 coiled-coil domain containing 103
CCDC71 coiled-coil domain containing 71
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD274 CD274 molecule
CD300LD CD300 molecule-like family member d
CD38 CD38 molecule
CD70 CD70 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD8A CD8a molecule
CDC25B cell division cycle 25B
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CHMP5 charged multivesicular body protein 5
CIITA class II, major histocompatibility complex, transactivator
CLEC9A C-type lectin domain family 9, member A
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
CMTM6 CKLF-like MARVEL transmembrane domain containing 6
CMTM8 CKLF-like MARVEL transmembrane domain containing 8
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CNTNAP3 contactin associated protein-like 3
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSB cathepsin B
CTSC cathepsin C
CTSO cathepsin O
CTSW cathepsin W
CWF19L2 CWF19-like 2, cell cycle control (S. pombe)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR6 chemokine (C-X-C motif) receptor 6
DALRD3 DALR anticodon binding domain containing 3
DCAF10 DDB1 and CUL4 associated factor 10
DCAKD dephospho-CoA kinase domain containing
DCTN4 dynactin 4 (p62)
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
DENND4C DENN/MADD domain containing 4C
DHRS3 dehydrogenase/reductase (SDR family) member 3
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DNAH17 dynein, axonemal, heavy chain 17
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNM3 dynamin 3
DOLPP1 dolichyldiphosphatase 1
DPYD dihydropyrimidine dehydrogenase
DSCAM Down syndrome cell adhesion molecule
DUSP6 dual specificity phosphatase 6
DUSP7 dual specificity phosphatase 7
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EFHD2 EF-hand domain family, member D2
ELP3 elongator acetyltransferase complex subunit 3
EPSTI1 epithelial stromal interaction 1 (breast)
ERI1 exoribonuclease 1
ERICH1 glutamate-rich 1
ETV7 ets variant 7
FAM149B1 family with sequence similarity 149, member B1
FAM160B2 family with sequence similarity 160, member B2
FAM186B family with sequence similarity 186, member B
FAM188B family with sequence similarity 188, member B
FAM201A family with sequence similarity 201, member A
FAM20C family with sequence similarity 20, member C
FAM3C family with sequence similarity 3, member C
FASLG Fas ligand (TNF superfamily, member 6)
FBXO6 F-box protein 6
FLT3LG fms-related tyrosine kinase 3 ligand
FOXC1 forkhead box C1
FOXK1 forkhead box K1
FOXP1 forkhead box P1
FSCN1 fascin actin-bundling protein 1
FXYD5 FXYD domain containing ion transport regulator 5
FYB FYN binding protein
G6PC3 glucose 6 phosphatase, catalytic, 3
GALT galactose-1-phosphate uridylyltransferase
GBP2 guanylate binding protein 2, interferon-inducible
GBP4 guanylate binding protein 4
GBP5 guanylate binding protein 5
GBP7 guanylate binding protein 7
GFI1 growth factor independent 1 transcription repressor
GLDC glycine dehydrogenase (decarboxylating)
GLI3 GLI family zinc finger 3
GNLY granulysin
GPR108 G protein-coupled receptor 108
GPR158 G protein-coupled receptor 158
GSAP gamma-secretase activating protein
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
HACD4 3-hydroxyacyl-CoA dehydratase 4
HAPLN3 hyaluronan and proteoglycan link protein 3
HCP5 HLA complex P5 (non-protein coding)
HDAC9 histone deacetylase 9
HEATR9 HEAT repeat containing 9
HERPUD2 HERPUD family member 2
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HLA-F major histocompatibility complex, class I, F
HOXA3 homeobox A3
HR hair growth associated
IDO1 indoleamine 2,3-dioxygenase 1
IFI16 interferon, gamma-inducible protein 16
IFI35 interferon-induced protein 35
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFIH1 interferon induced with helicase C domain 1
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFITM1 interferon induced transmembrane protein 1
IFNG interferon, gamma
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IFT74 intraflagellar transport 74
IGFL4 IGF-like family member 4
IL12RB1 interleukin 12 receptor, beta 1
IL12RB2 interleukin 12 receptor, beta 2
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL17RE interleukin 17 receptor E
IL18BP interleukin 18 binding protein
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRF1 interferon regulatory factor 1
IRF2 interferon regulatory factor 2
IRF7 interferon regulatory factor 7
IRF9 interferon regulatory factor 9
IRGM immunity-related GTPase family, M
JAK2 Janus kinase 2
JAKMIP1 janus kinase and microtubule interacting protein 1
KBTBD2 kelch repeat and BTB (POZ) domain containing 2
KCTD14 potassium channel tetramerization domain containing 14
KGFLP2 keratinocyte growth factor-like protein 2
KIAA0020 KIAA0020
KIF24 kinesin family member 24
KLHL9 kelch-like family member 9
KLKB1 kallikrein B, plasma (Fletcher factor) 1
KLLN killin, p53-regulated DNA replication inhibitor
KLRD1 killer cell lectin-like receptor subfamily D, member 1
LAG3 lymphocyte-activation gene 3
LAP3 leucine aminopeptidase 3
LBH limb bud and heart development
LHX1 LIM homeobox 1
LIMK1 LIM domain kinase 1
LINC00207 long intergenic non-protein coding RNA 207
LOC100133669 uncharacterized LOC100133669
LOC388692 uncharacterized LOC388692
LOC441454 prothymosin, alpha pseudogene
LOC644936 actin, beta pseudogene
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3
LRRTM2 leucine rich repeat transmembrane neuronal 2
LRSAM1 leucine rich repeat and sterile alpha motif containing 1
LSM12 LSM12 homolog (S. cerevisiae)
LY6E lymphocyte antigen 6 complex, locus E
LYZL6 lysozyme-like 6
MALT1 MALT1 paracaspase
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MB21D1 Mab-21 domain containing 1
MELK maternal embryonic leucine zipper kinase
MEP1B meprin A, beta
MICALL2 MICAL-like 2
MRGPRX3 MAS-related GPR, member X3
MRPL32 mitochondrial ribosomal protein L32
MRPL44 mitochondrial ribosomal protein L44
MSRB1 methionine sulfoxide reductase B1
MX1 MX dynamin-like GTPase 1
MYO7A myosin VIIA
N4BP2L1 NEDD4 binding protein 2-like 1
NET1 neuroepithelial cell transforming 1
NFX1 nuclear transcription factor, X-box binding 1
NICN1 nicolin 1
NLRC5 NLR family, CARD domain containing 5
NMI N-myc (and STAT) interactor
NOD1 nucleotide-binding oligomerization domain containing 1
NOTCH1 notch 1
NT5C3A 5'-nucleotidase, cytosolic IIIA
NUB1 negative regulator of ubiquitin-like proteins 1
NUDCD3 NudC domain containing 3
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
ODF2L outer dense fiber of sperm tails 2-like
ODF3B outer dense fiber of sperm tails 3B
OOEP oocyte expressed protein
OPTN optineurin
OR1J2 olfactory receptor, family 1, subfamily J, member 2
OR1J4 olfactory receptor, family 1, subfamily J, member 4
OR1Q1 olfactory receptor, family 1, subfamily Q, member 1
OR2J3 olfactory receptor, family 2, subfamily J, member 3
OR2M3 olfactory receptor, family 2, subfamily M, member 3
OR52B4 olfactory receptor, family 52, subfamily B, member 4 (gene/pseudogene)
OSBPL3 oxysterol binding protein-like 3
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARP10 poly (ADP-ribose) polymerase family, member 10
PARP12 poly (ADP-ribose) polymerase family, member 12
PARP14 poly (ADP-ribose) polymerase family, member 14
PARP3 poly (ADP-ribose) polymerase family, member 3
PARP8 poly (ADP-ribose) polymerase family, member 8
PATL2 protein associated with topoisomerase II homolog 2 (yeast)
PCDH7 protocadherin 7
PCED1B PC-esterase domain containing 1B
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PLAA phospholipase A2-activating protein
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
PLRG1 pleiotropic regulator 1
PML promyelocytic leukemia
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POLR1E polymerase (RNA) I polypeptide E, 53kDa
POM121L10P POM121 transmembrane nucleoporin-like 10, pseudogene
POTEE POTE ankyrin domain family, member E
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRDM16 PR domain containing 16
PRF1 perforin 1 (pore forming protein)
PRKCD protein kinase C, delta
PRKD2 protein kinase D2
PRPF40B PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTEN phosphatase and tensin homolog
PTK2B protein tyrosine kinase 2 beta
PYGB phosphorylase, glycogen; brain
RAB19 RAB19, member RAS oncogene family
RAD51AP2 RAD51 associated protein 2
RAG1 recombination activating gene 1
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RBM43 RNA binding motif protein 43
RETNLB resistin like beta
RFX3 regulatory factor X, 3 (influences HLA class II expression)
RGPD1 RANBP2-like and GRIP domain containing 1
RGS3 regulator of G-protein signaling 3
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNASE3 ribonuclease, RNase A family, 3
RNF114 ring finger protein 114
RNF213 ring finger protein 213
RNF38 ring finger protein 38
RP1L1 retinitis pigmentosa 1-like 1
RPL29P2 ribosomal protein L29 pseudogene 2
RPP25L ribonuclease P/MRP 25kDa subunit-like
RRAGA Ras-related GTP binding A
RTP4 receptor (chemosensory) transporter protein 4
RUNX1 runt-related transcription factor 1
SAMD9L sterile alpha motif domain containing 9-like
SCAMP4 secretory carrier membrane protein 4
SCO2 SCO2 cytochrome c oxidase assembly protein
SDSL serine dehydratase-like
SEC14L2 SEC14-like 2 (S. cerevisiae)
SECTM1 secreted and transmembrane 1
SGK223 homolog of rat pragma of Rnd2
SHB Src homology 2 domain containing adaptor protein B
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SHC4 SHC (Src homology 2 domain containing) family, member 4
SHISA5 shisa family member 5
SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene)
SIGMAR1 sigma non-opioid intracellular receptor 1
SIRPD signal-regulatory protein delta
SIRPG signal-regulatory protein gamma
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC16A13 solute carrier family 16, member 13
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC25A51 solute carrier family 25, member 51
SLC25A52 solute carrier family 25, member 52
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLCO1B7 solute carrier organic anion transporter family, member 1B7 (non-functional)
SMIM3 small integral membrane protein 3
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SNORA44 small nucleolar RNA, H/ACA box 44
SNORA72 small nucleolar RNA, H/ACA box 72
SOX7 SRY (sex determining region Y)-box 7
SOX9 SRY (sex determining region Y)-box 9
SP100 SP100 nuclear antigen
SP110 SP110 nuclear body protein
SPATA6L spermatogenesis associated 6-like
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STOM stomatin
STOML1 stomatin (EPB72)-like 1
STRA6 stimulated by retinoic acid 6
STX11 syntaxin 11
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TARP TCR gamma alternate reading frame protein
TBX21 T-box 21
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TDRD7 tudor domain containing 7
TEX33 testis expressed 33
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
THEMIS2 thymocyte selection associated family member 2
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
TLE4 transducin-like enhancer of split 4
TMEM132A transmembrane protein 132A
TMEM229B transmembrane protein 229B
TMEM92 transmembrane protein 92
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRAFD1 TRAF-type zinc finger domain containing 1
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRIB2 tribbles pseudokinase 2
TRIL TLR4 interactor with leucine-rich repeats
TRIM14 tripartite motif containing 14
TRIM21 tripartite motif containing 21
TRIM22 tripartite motif containing 22
TRIM35 tripartite motif containing 35
TRIM78P tripartite motif containing 78, pseudogene
TRMT10B tRNA methyltransferase 10 homolog B (S. cerevisiae)
TTC24 tetratricopeptide repeat domain 24
UBA7 ubiquitin-like modifier activating enzyme 7
UBAP1 ubiquitin associated protein 1
UBAP2 ubiquitin associated protein 2
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBE2R2 ubiquitin-conjugating enzyme E2R 2
USP18 ubiquitin specific peptidase 18
USP42 ubiquitin specific peptidase 42
UTS2 urotensin 2
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
VSTM1 V-set and transmembrane domain containing 1
WARS tryptophanyl-tRNA synthetase
WDFY1 WD repeat and FYVE domain containing 1
WDR25 WD repeat domain 25
WFDC8 WAP four-disulfide core domain 8
XAF1 XIAP associated factor 1
ZBP1 Z-DNA binding protein 1
ZBTB5 zinc finger and BTB domain containing 5
ZC3H6 zinc finger CCCH-type containing 6
ZCCHC7 zinc finger, CCHC domain containing 7
ZFAT-AS1 ZFAT antisense RNA 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZMYND15 zinc finger, MYND-type containing 15
ZNF596 zinc finger protein 596
ZNF658 zinc finger protein 658
ZNF683 zinc finger protein 683
ZNF92 zinc finger protein 92

low expression

Symbol Name
METTL9 methyltransferase like 9
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD)
ZNF20 zinc finger protein 20