Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5331-01A-02R-1873-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

349 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5331-01A-02R-1873-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AADACL3 arylacetamide deacetylase-like 3
ACBD5 acyl-CoA binding domain containing 5
ACOT13 acyl-CoA thioesterase 13
ACSL5 acyl-CoA synthetase long-chain family member 5
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADAP2 ArfGAP with dual PH domains 2
ADAR adenosine deaminase, RNA-specific
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGPS alkylglycerone phosphate synthase
AIM2 absent in melanoma 2
ALAS1 5'-aminolevulinate synthase 1
ALMS1P Alstrom syndrome 1 pseudogene
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD31 ankyrin repeat domain 31
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
AP1B1 adaptor-related protein complex 1, beta 1 subunit
APOL2 apolipoprotein L, 2
APOL3 apolipoprotein L, 3
APOL4 apolipoprotein L, 4
APOL6 apolipoprotein L, 6
ARL5A ADP-ribosylation factor-like 5A
ASAH2B N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
AVPR1A arginine vasopressin receptor 1A
BAG6 BCL2-associated athanogene 6
BAK1 BCL2-antagonist/killer 1
BATF2 basic leucine zipper transcription factor, ATF-like 2
BMP2K BMP2 inducible kinase
BRPF3 bromodomain and PHD finger containing, 3
BTN3A3 butyrophilin, subfamily 3, member A3
BYSL bystin-like
C19ORF66 chromosome 19 open reading frame 66
C2CD4A C2 calcium-dependent domain containing 4A
C6ORF106 chromosome 6 open reading frame 106
C6ORF132 chromosome 6 open reading frame 132
C9ORF41 chromosome 9 open reading frame 41
CALCRL calcitonin receptor-like
CARD17 caspase recruitment domain family, member 17
CASP8 caspase 8, apoptosis-related cysteine peptidase
CATSPERB catsper channel auxiliary subunit beta
CCL7 chemokine (C-C motif) ligand 7
CCL8 chemokine (C-C motif) ligand 8
CCNT2 cyclin T2
CD2AP CD2-associated protein
CDSN corneodesmosin
CELA2B chymotrypsin-like elastase family, member 2B
CFB complement factor B
CIR1 corepressor interacting with RBPJ, 1
CLEC4C C-type lectin domain family 4, member C
CLEC4E C-type lectin domain family 4, member E
CLEC6A C-type lectin domain family 6, member A
CLEC7A C-type lectin domain family 7, member A
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
CMTR1 cap methyltransferase 1
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COBLL1 cordon-bleu WH2 repeat protein-like 1
COG8 component of oligomeric golgi complex 8
CUL7 cullin 7
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR2P1 chemokine (C-X-C motif) receptor 2 pseudogene 1
CYP8B1 cytochrome P450, family 8, subfamily B, polypeptide 1
DCAF17 DDB1 and CUL4 associated factor 17
DCTN4 dynactin 4 (p62)
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DHRS1 dehydrogenase/reductase (SDR family) member 1
DMRTA1 DMRT-like family A1
DSC2 desmocollin 2
DSG1 desmoglein 1
DSP desmoplakin
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
EAF1 ELL associated factor 1
ECD ecdysoneless homolog (Drosophila)
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ELOVL7 ELOVL fatty acid elongase 7
EPC2 enhancer of polycomb homolog 2 (Drosophila)
EPGN epithelial mitogen
EPPK1 epiplakin 1
ERAP2 endoplasmic reticulum aminopeptidase 2
ETV7 ets variant 7
EXOC2 exocyst complex component 2
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM126B family with sequence similarity 126, member B
FAM63A family with sequence similarity 63, member A
FAM83B family with sequence similarity 83, member B
FAM8A1 family with sequence similarity 8, member A1
FAM98A family with sequence similarity 98, member A
FBXL18 F-box and leucine-rich repeat protein 18
FBXO6 F-box protein 6
FBXO9 F-box protein 9
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FCGR1C Fc fragment of IgG, high affinity Ic, receptor (CD64), pseudogene
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCHSD1 FCH and double SH3 domains 1
FGF22 fibroblast growth factor 22
FIGN fidgetin
FMNL2 formin-like 2
FPR3 formyl peptide receptor 3
GAB1 GRB2-associated binding protein 1
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GBP1 guanylate binding protein 1, interferon-inducible
GBP5 guanylate binding protein 5
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GCSH glycine cleavage system protein H (aminomethyl carrier)
GFOD1 glucose-fructose oxidoreductase domain containing 1
GLDC glycine dehydrogenase (decarboxylating)
GMEB1 glucocorticoid modulatory element binding protein 1
GORASP2 golgi reassembly stacking protein 2, 55kDa
GPBAR1 G protein-coupled bile acid receptor 1
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTPBP2 GTP binding protein 2
HCP5 HLA complex P5 (non-protein coding)
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HEXIM1 hexamethylene bis-acetamide inducible 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BC histone cluster 1, H2bc
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-E major histocompatibility complex, class I, E
HLA-J major histocompatibility complex, class I, J (pseudogene)
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOMER1 homer scaffolding protein 1
HOXD8 homeobox D8
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
HSPA4L heat shock 70kDa protein 4-like
HSPA8 heat shock 70kDa protein 8
HTT huntingtin
IFI35 interferon-induced protein 35
IFI44L interferon-induced protein 44-like
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IL12RB1 interleukin 12 receptor, beta 1
IL12RB2 interleukin 12 receptor, beta 2
IL18BP interleukin 18 binding protein
IL36RN interleukin 36 receptor antagonist
IRF7 interferon regulatory factor 7
IRF8 interferon regulatory factor 8
IVL involucrin
KBTBD6 kelch repeat and BTB (POZ) domain containing 6
KCTD14 potassium channel tetramerization domain containing 14
KCTD4 potassium channel tetramerization domain containing 4
KDM5C lysine (K)-specific demethylase 5C
KIAA0922 KIAA0922
KIAA1033 KIAA1033
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
KLHL18 kelch-like family member 18
KPRP keratinocyte proline-rich protein
KRT6B keratin 6B, type II
KRT80 keratin 80, type II
LAP3 leucine aminopeptidase 3
LCE1D late cornified envelope 1D
LCE2A late cornified envelope 2A
LCE2B late cornified envelope 2B
LCE2C late cornified envelope 2C
LCE2D late cornified envelope 2D
LCE3B late cornified envelope 3B
LCE3E late cornified envelope 3E
LCE6A late cornified envelope 6A
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LMBRD1 LMBR1 domain containing 1
LOC285629 uncharacterized LOC285629
LRCH2 leucine-rich repeats and calponin homology (CH) domain containing 2
LRRTM2 leucine rich repeat transmembrane neuronal 2
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAPK13 mitogen-activated protein kinase 13
MAPK14 mitogen-activated protein kinase 14
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
MEFV Mediterranean fever
METTL14 methyltransferase like 14
METTL8 methyltransferase like 8
MLKL mixed lineage kinase domain-like
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
MOV10 Mov10 RISC complex RNA helicase
MPEG1 macrophage expressed 1
MPL MPL proto-oncogene, thrombopoietin receptor
MRPS10 mitochondrial ribosomal protein S10
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
MYD88 myeloid differentiation primary response 88
NEK7 NIMA-related kinase 7
NELL2 NEL-like 2 (chicken)
NEU2 sialidase 2 (cytosolic sialidase)
NIFK nucleolar protein interacting with the FHA domain of MKI67
NMI N-myc (and STAT) interactor
NOL7 nucleolar protein 7, 27kDa
NOP9 NOP9 nucleolar protein
NT5C3A 5'-nucleotidase, cytosolic IIIA
NWD2 NACHT and WD repeat domain containing 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OAZ3 ornithine decarboxylase antizyme 3
ODF2L outer dense fiber of sperm tails 2-like
OIT3 oncoprotein induced transcript 3
OPN1LW opsin 1 (cone pigments), long-wave-sensitive
OPN1MW opsin 1 (cone pigments), medium-wave-sensitive
OR4E2 olfactory receptor, family 4, subfamily E, member 2
ORC4 origin recognition complex, subunit 4
PANK3 pantothenate kinase 3
PAPL iron/zinc purple acid phosphatase-like protein
PAQR5 progestin and adipoQ receptor family member V
PARP14 poly (ADP-ribose) polymerase family, member 14
PCDHGB7 protocadherin gamma subfamily B, 7
PDE12 phosphodiesterase 12
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PKP1 plakophilin 1
PLA2G2E phospholipase A2, group IIE
PLA2G4E phospholipase A2, group IVE
PLAGL1 pleiomorphic adenoma gene-like 1
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2
PML promyelocytic leukemia
PNPLA1 patatin-like phospholipase domain containing 1
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPIG peptidylprolyl isomerase G (cyclophilin G)
PRDM4 PR domain containing 4
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRMT9 protein arginine methyltransferase 9
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
PSD4 pleckstrin and Sec7 domain containing 4
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSORS1C2 psoriasis susceptibility 1 candidate 2
PTCRA pre T-cell antigen receptor alpha
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PURA purine-rich element binding protein A
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RAB5A RAB5A, member RAS oncogene family
RANBP2 RAN binding protein 2
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RARS arginyl-tRNA synthetase
RASIP1 Ras interacting protein 1
RBM43 RNA binding motif protein 43
RBM45 RNA binding motif protein 45
RIF1 replication timing regulatory factor 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK3 receptor-interacting serine-threonine kinase 3
RNASE7 ribonuclease, RNase A family, 7
RNF213 ring finger protein 213
RNF222 ring finger protein 222
RPL7L1 ribosomal protein L7-like 1
RPTOR regulatory associated protein of MTOR, complex 1
RSAD2 radical S-adenosyl methionine domain containing 2
SAMD9 sterile alpha motif domain containing 9
SAMHD1 SAM domain and HD domain 1
SCRN3 secernin 3
SEC16B SEC16 homolog B (S. cerevisiae)
SEPT10 septin 10
SIGLEC14 sialic acid binding Ig-like lectin 14
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLAMF7 SLAM family member 7
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC25A30 solute carrier family 25, member 30
SLC2A7 solute carrier family 2 (facilitated glucose transporter), member 7
SLFN12L schlafen family member 12-like
SMIM14 small integral membrane protein 14
SOWAHC sosondowah ankyrin repeat domain family member C
SP110 SP110 nuclear body protein
SP140L SP140 nuclear body protein-like
SPIN4 spindlin family, member 4
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative)
SPOPL speckle-type POZ protein-like
SPRR2G small proline-rich protein 2G
SSB Sjogren syndrome antigen B (autoantigen La)
SSR1 signal sequence receptor, alpha
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STX11 syntaxin 11
SYCE1 synaptonemal complex central element protein 1
TANK TRAF family member-associated NFKB activator
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBCC tubulin folding cofactor C
TLR3 toll-like receptor 3
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TMEM150B transmembrane protein 150B
TMEM217 transmembrane protein 217
TMEM33 transmembrane protein 33
TMEM88B transmembrane protein 88B
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TPI1P2 triosephosphate isomerase 1 pseudogene 2
TRAFD1 TRAF-type zinc finger domain containing 1
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRIM14 tripartite motif containing 14
TRIM21 tripartite motif containing 21
TRIM22 tripartite motif containing 22
TRIM25 tripartite motif containing 25
TRIM26 tripartite motif containing 26
TRIM38 tripartite motif containing 38
TRIM5 tripartite motif containing 5
TRIM56 tripartite motif containing 56
TRIM58 tripartite motif containing 58
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae)
TRPS1 trichorhinophalangeal syndrome I
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TSPYL1 TSPY-like 1
TUBB2A tubulin, beta 2A class IIa
TWF1 twinfilin actin binding protein 1
TXLNG taxilin gamma
UBA7 ubiquitin-like modifier activating enzyme 7
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBQLN2 ubiquilin 2
UFSP1 UFM1-specific peptidase 1 (non-functional)
UHMK1 U2AF homology motif (UHM) kinase 1
USP38 ubiquitin specific peptidase 38
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
VIPR1 vasoactive intestinal peptide receptor 1
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
WARS tryptophanyl-tRNA synthetase
WDFY1 WD repeat and FYVE domain containing 1
WDR33 WD repeat domain 33
WFDC11 WAP four-disulfide core domain 11
XAF1 XIAP associated factor 1
XPO5 exportin 5
YOD1 YOD1 deubiquitinase
YTHDC2 YTH domain containing 2
ZBED6CL ZBED6 C-terminal like
ZBTB37 zinc finger and BTB domain containing 37
ZBTB9 zinc finger and BTB domain containing 9
ZFP91-CNTF ZFP91-CNTF readthrough (NMD candidate)
ZFYVE26 zinc finger, FYVE domain containing 26
ZHX1 zinc fingers and homeoboxes 1
ZNF426 zinc finger protein 426
ZNF562 zinc finger protein 562
ZNF702P zinc finger protein 702, pseudogene
ZNF860 zinc finger protein 860
ZSCAN12P1 zinc finger and SCAN domain containing 12 pseudogene 1
ZSCAN31 zinc finger and SCAN domain containing 31

low expression

Symbol Name
COPG2 coatomer protein complex, subunit gamma 2
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B