Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A499-01A-11R-A24H-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

439 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A499-01A-11R-A24H-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ACAD11 acyl-CoA dehydrogenase family, member 11
ACSL4 acyl-CoA synthetase long-chain family member 4
ADAM8 ADAM metallopeptidase domain 8
ADGRD2 adhesion G protein-coupled receptor D2
ADGRE5 adhesion G protein-coupled receptor E5
AGAP5 ArfGAP with GTPase domain, ankyrin repeat and PH domain 5
AGMAT agmatine ureohydrolase (agmatinase)
AGTPBP1 ATP/GTP binding protein 1
AIM2 absent in melanoma 2
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALG10B ALG10B, alpha-1,2-glucosyltransferase
ALMS1P Alstrom syndrome 1 pseudogene
ALX1 ALX homeobox 1
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
AP1S3 adaptor-related protein complex 1, sigma 3 subunit
APOL1 apolipoprotein L, 1
APOL4 apolipoprotein L, 4
APOL6 apolipoprotein L, 6
APOO apolipoprotein O
ARHGAP4 Rho GTPase activating protein 4
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATAD5 ATPase family, AAA domain containing 5
ATR ATR serine/threonine kinase
BATF2 basic leucine zipper transcription factor, ATF-like 2
BBX bobby sox homolog (Drosophila)
BCCIP BRCA2 and CDKN1A interacting protein
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BMS1P5 BMS1 ribosome biogenesis factor pseudogene 5
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BUB3 BUB3 mitotic checkpoint protein
C14ORF39 chromosome 14 open reading frame 39
C3ORF38 chromosome 3 open reading frame 38
C6ORF10 chromosome 6 open reading frame 10
C9ORF40 chromosome 9 open reading frame 40
C9ORF64 chromosome 9 open reading frame 64
C9ORF84 chromosome 9 open reading frame 84
C9ORF89 chromosome 9 open reading frame 89
CA5BP1 carbonic anhydrase VB pseudogene 1
CBWD3 COBW domain containing 3
CCAR1 cell division cycle and apoptosis regulator 1
CCDC14 coiled-coil domain containing 14
CCDC144B coiled-coil domain containing 144B (pseudogene)
CCDC18 coiled-coil domain containing 18
CCDC68 coiled-coil domain containing 68
CCDC70 coiled-coil domain containing 70
CD38 CD38 molecule
CDC7 cell division cycle 7
CDCA2 cell division cycle associated 2
CDK1 cyclin-dependent kinase 1
CDKN2A-AS1 CDKN2A antisense RNA 1 (head to head)
CDKN3 cyclin-dependent kinase inhibitor 3
CDV3 CDV3 homolog (mouse)
CEMIP cell migration inducing protein, hyaluronan binding
CENPE centromere protein E, 312kDa
CENPI centromere protein I
CENPQ centromere protein Q
CEP120 centrosomal protein 120kDa
CEP78 centrosomal protein 78kDa
CGGBP1 CGG triplet repeat binding protein 1
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4
CHM choroideremia (Rab escort protein 1)
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CLSPN claspin
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
CMTM7 CKLF-like MARVEL transmembrane domain containing 7
CNOT10 CCR4-NOT transcription complex, subunit 10
COMMD2 COMM domain containing 2
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CSNK1G3 casein kinase 1, gamma 3
CTAGE4 CTAGE family, member 4
CTAGE6 CTAGE family, member 6
CTAGE9 CTAGE family, member 9
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR2P1 chemokine (C-X-C motif) receptor 2 pseudogene 1
CXORF23 chromosome X open reading frame 23
CXORF58 chromosome X open reading frame 58
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DAB2IP DAB2 interacting protein
DBF4 DBF4 zinc finger
DBR1 debranching RNA lariats 1
DCAF10 DDB1 and CUL4 associated factor 10
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
DEK DEK proto-oncogene
DEPDC1 DEP domain containing 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNA2 DNA replication helicase/nuclease 2
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DTX3L deltex 3 like, E3 ubiquitin ligase
DUSP6 dual specificity phosphatase 6
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
E2F7 E2F transcription factor 7
ECT2 epithelial cell transforming 2
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EID3 EP300 interacting inhibitor of differentiation 3
EIF1AX eukaryotic translation initiation factor 1A, X-linked
ERCC6L excision repair cross-complementation group 6-like
ERI1 exoribonuclease 1
ETV5 ets variant 5
EXOC5 exocyst complex component 5
EXOG endo/exonuclease (5'-3'), endonuclease G-like
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM106A family with sequence similarity 106, member A
FAM111B family with sequence similarity 111, member B
FAM120A family with sequence similarity 120A
FAM156A family with sequence similarity 156, member A
FAM182A family with sequence similarity 182, member A
FAM182B family with sequence similarity 182, member B
FAM199X family with sequence similarity 199, X-linked
FAM72B family with sequence similarity 72, member B
FAM72D family with sequence similarity 72, member D
FANCB Fanconi anemia, complementation group B
FANCC Fanconi anemia, complementation group C
FANCM Fanconi anemia, complementation group M
FAR1 fatty acyl CoA reductase 1
FBXO5 F-box protein 5
FGF3 fibroblast growth factor 3
FKTN fukutin
FLNA filamin A, alpha
FMR1 fragile X mental retardation 1
FMR1-AS1 FMR1 antisense RNA 1
FOXG1 forkhead box G1
FRMPD4 FERM and PDZ domain containing 4
FSD1L fibronectin type III and SPRY domain containing 1-like
FUBP1 far upstream element (FUSE) binding protein 1
FUBP3 far upstream element (FUSE) binding protein 3
GBP1 guanylate binding protein 1, interferon-inducible
GBP5 guanylate binding protein 5
GEN1 GEN1 Holliday junction 5' flap endonuclease
GLB1L3 galactosidase, beta 1-like 3
GLE1 GLE1 RNA export mediator
GMFB glia maturation factor, beta
GMNN geminin, DNA replication inhibitor
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GOLGA2P5 golgin A2 pseudogene 5
GPR141 G protein-coupled receptor 141
GRK5 G protein-coupled receptor kinase 5
GSAP gamma-secretase activating protein
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa
HCCS holocytochrome c synthase
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HLTF helicase-like transcription factor
HNF4G hepatocyte nuclear factor 4, gamma
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9)
HNRNPK heterogeneous nuclear ribonucleoprotein K
HS6ST2 heparan sulfate 6-O-sulfotransferase 2
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IARS isoleucyl-tRNA synthetase
IDO1 indoleamine 2,3-dioxygenase 1
IFI16 interferon, gamma-inducible protein 16
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFIH1 interferon induced with helicase C domain 1
IFITM1 interferon induced transmembrane protein 1
IFNG interferon, gamma
IFRD1 interferon-related developmental regulator 1
IFT74 intraflagellar transport 74
IL12RB2 interleukin 12 receptor, beta 2
IL1RAP interleukin 1 receptor accessory protein
INIP INTS3 and NABP interacting protein
INPP5F inositol polyphosphate-5-phosphatase F
IQCG IQ motif containing G
JAK2 Janus kinase 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2
KCTD14 potassium channel tetramerization domain containing 14
KCTD9 potassium channel tetramerization domain containing 9
KDM6A lysine (K)-specific demethylase 6A
KIAA0040 KIAA0040
KIAA0368 KIAA0368
KIAA1524 KIAA1524
KIF15 kinesin family member 15
KIF18A kinesin family member 18A
KIF24 kinesin family member 24
KIF4A kinesin family member 4A
KIF4B kinesin family member 4B
LAMP3 lysosomal-associated membrane protein 3
LAP3 leucine aminopeptidase 3
LARP4 La ribonucleoprotein domain family, member 4
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LHFPL4 lipoma HMGIC fusion partner-like 4
LIN9 lin-9 DREAM MuvB core complex component
LINC00574 long intergenic non-protein coding RNA 574
LINC01559 long intergenic non-protein coding RNA 1559
LOC100129534 small nuclear ribonucleoprotein polypeptide N pseudogene
LOC100132111 uncharacterized LOC100132111
LOC100272216 uncharacterized LOC100272216
LOC388692 uncharacterized LOC388692
LOC399815 chromosome 10 open reading frame 88 pseudogene
LOC647859 occludin pseudogene
LRCH2 leucine-rich repeats and calponin homology (CH) domain containing 2
LRR1 leucine rich repeat protein 1
LRRC58 leucine rich repeat containing 58
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MCMBP minichromosome maintenance complex binding protein
MCTP1 multiple C2 domains, transmembrane 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED14 mediator complex subunit 14
MEF2BNB-MEF2B MEF2BNB-MEF2B readthrough
MEI1 meiosis inhibitor 1
MELK maternal embryonic leucine zipper kinase
METTL15 methyltransferase like 15
METTL6 methyltransferase like 6
MICB MHC class I polypeptide-related sequence B
MIER1 mesoderm induction early response 1, transcriptional regulator
MIS18BP1 MIS18 binding protein 1
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MLH3 mutL homolog 3
MMS22L MMS22-like, DNA repair protein
MOV10 Mov10 RISC complex RNA helicase
MRPL3 mitochondrial ribosomal protein L3
MRPS22 mitochondrial ribosomal protein S22
MSANTD3 Myb/SANT-like DNA-binding domain containing 3
MSL3 male-specific lethal 3 homolog (Drosophila)
MTBP MDM2 binding protein
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NCAPD3 non-SMC condensin II complex, subunit D3
NCAPG non-SMC condensin I complex, subunit G
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
NEFH neurofilament, heavy polypeptide
NEK7 NIMA-related kinase 7
NIPSNAP3A nipsnap homolog 3A (C. elegans)
NKTR natural killer cell triggering receptor
NOL8 nucleolar protein 8
NOTCH1 notch 1
NR2C1 nuclear receptor subfamily 2, group C, member 1
NUP210 nucleoporin 210kDa
NUP62CL nucleoporin 62kDa C-terminal like
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
ODF2 outer dense fiber of sperm tails 2
ODF2L outer dense fiber of sperm tails 2-like
OR13H1 olfactory receptor, family 13, subfamily H, member 1
OR1D4 olfactory receptor, family 1, subfamily D, member 4 (gene/pseudogene)
OR5K1 olfactory receptor, family 5, subfamily K, member 1
ORC3 origin recognition complex, subunit 3
OTUD3 OTU deubiquitinase 3
PALM2 paralemmin 2
PAQR9 progestin and adipoQ receptor family member IX
PARP14 poly (ADP-ribose) polymerase family, member 14
PARP9 poly (ADP-ribose) polymerase family, member 9
PCGF6 polycomb group ring finger 6
PCNP PEST proteolytic signal containing nuclear protein
PDCL phosducin-like
PDE10A phosphodiesterase 10A
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1
PHF6 PHD finger protein 6
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PLAA phospholipase A2-activating protein
PLK4 polo-like kinase 4
PLSCR1 phospholipid scramblase 1
PLXNA1 plexin A1
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
POLQ polymerase (DNA directed), theta
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PRDM5 PR domain containing 5
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PRSS48 protease, serine, 48
PRTFDC1 phosphoribosyl transferase domain containing 1
PSAT1 phosphoserine aminotransferase 1
PSIP1 PC4 and SFRS1 interacting protein 1
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PTAR1 protein prenyltransferase alpha subunit repeat containing 1
QRFPR pyroglutamylated RFamide peptide receptor
QSER1 glutamine and serine rich 1
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAB43 RAB43, member RAS oncogene family
RABL3 RAB, member of RAS oncogene family-like 3
RACGAP1 Rac GTPase activating protein 1
RACGAP1P Rac GTPase activating protein 1 pseudogene
RAD18 RAD18 E3 ubiquitin protein ligase
RAP2C RAP2C, member of RAS oncogene family
RBBP7 retinoblastoma binding protein 7
RBM12B RNA binding motif protein 12B
RBM14 RNA binding motif protein 14
RBM15 RNA binding motif protein 15
RBM25 RNA binding motif protein 25
RBM41 RNA binding motif protein 41
RBMX RNA binding motif protein, X-linked
REC8 REC8 meiotic recombination protein
RFC3 replication factor C (activator 1) 3, 38kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RFK riboflavin kinase
RFPL1S RFPL1 antisense RNA 1
RFX3 regulatory factor X, 3 (influences HLA class II expression)
RFXAP regulatory factor X-associated protein
RGPD8 RANBP2-like and GRIP domain containing 8
RIBC2 RIB43A domain with coiled-coils 2
RLIM ring finger protein, LIM domain interacting
RMI1 RecQ mediated genome instability 1
RNF114 ring finger protein 114
RNF212 ring finger protein 212
RNF213 ring finger protein 213
RP2 retinitis pigmentosa 2 (X-linked recessive)
RRM1 ribonucleotide reductase M1
RSAD2 radical S-adenosyl methionine domain containing 2
RTP4 receptor (chemosensory) transporter protein 4
RUFY2 RUN and FYVE domain containing 2
RUVBL1 RuvB-like AAA ATPase 1
SAMD9L sterile alpha motif domain containing 9-like
SAMHD1 SAM domain and HD domain 1
SASS6 spindle assembly 6 homolog (C. elegans)
SAV1 salvador family WW domain containing protein 1
SCML1 sex comb on midleg-like 1 (Drosophila)
SEC16B SEC16 homolog B (S. cerevisiae)
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SGOL1 shugoshin-like 1 (S. pombe)
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC25A51P1 solute carrier family 25, member 51 pseudogene 1
SLC25A52 solute carrier family 25, member 52
SLC35G2 solute carrier family 35, member G2
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLFN12L schlafen family member 12-like
SLFN13 schlafen family member 13
SLFN5 schlafen family member 5
SMC1A structural maintenance of chromosomes 1A
SMC1B structural maintenance of chromosomes 1B
SMC2 structural maintenance of chromosomes 2
SMC3 structural maintenance of chromosomes 3
SMC4 structural maintenance of chromosomes 4
SMC5 structural maintenance of chromosomes 5
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOCS4 suppressor of cytokine signaling 4
SPIN1 spindlin 1
SRSF1 serine/arginine-rich splicing factor 1
SRSF10 serine/arginine-rich splicing factor 10
SSH1 slingshot protein phosphatase 1
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
STAG1 stromal antigen 1
STAG3 stromal antigen 3
STARD6 StAR-related lipid transfer (START) domain containing 6
STIL SCL/TAL1 interrupting locus
STX17 syntaxin 17
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYCP2 synaptonemal complex protein 2
SYNE2 spectrin repeat containing, nuclear envelope 2
TAMM41 TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae)
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TCAM1P testicular cell adhesion molecule 1, pseudogene
TDRD7 tudor domain containing 7
TEX10 testis expressed 10
TFB1M transcription factor B1, mitochondrial
TFDP3 transcription factor Dp family, member 3
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMED8 transmembrane emp24 protein transport domain containing 8
TMEM229B transmembrane protein 229B
TMPO thymopoietin
TMX1 thioredoxin-related transmembrane protein 1
TOPBP1 topoisomerase (DNA) II binding protein 1
TRA2B transformer 2 beta homolog (Drosophila)
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM22 tripartite motif containing 22
TRIM25 tripartite motif containing 25
TRIM59 tripartite motif containing 59
TRIM69 tripartite motif containing 69
TRIM74 tripartite motif containing 74
TRMT10B tRNA methyltransferase 10 homolog B (S. cerevisiae)
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
TTF1 transcription termination factor, RNA polymerase I
TTK TTK protein kinase
TUBB8 tubulin, beta 8 class VIII
U2SURP U2 snRNP-associated SURP domain containing
UBA5 ubiquitin-like modifier activating enzyme 5
UBA6 ubiquitin-like modifier activating enzyme 6
UBQLN1 ubiquilin 1
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
UGT8 UDP glycosyltransferase 8
USP1 ubiquitin specific peptidase 1
USP18 ubiquitin specific peptidase 18
VBP1 von Hippel-Lindau binding protein 1
VSIG1 V-set and immunoglobulin domain containing 1
WARS tryptophanyl-tRNA synthetase
WDFY1 WD repeat and FYVE domain containing 1
WDHD1 WD repeat and HMG-box DNA binding protein 1
WDR44 WD repeat domain 44
WNK3 WNK lysine deficient protein kinase 3
WSB1 WD repeat and SOCS box containing 1
XAF1 XIAP associated factor 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XIST X inactive specific transcript (non-protein coding)
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
XPO1 exportin 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRN1 5'-3' exoribonuclease 1
ZBTB11 zinc finger and BTB domain containing 11
ZBTB34 zinc finger and BTB domain containing 34
ZBTB6 zinc finger and BTB domain containing 6
ZFX zinc finger protein, X-linked
ZNF100 zinc finger protein 100
ZNF169 zinc finger protein 169
ZNF311 zinc finger protein 311
ZNF326 zinc finger protein 326
ZNF367 zinc finger protein 367
ZNF449 zinc finger protein 449
ZNF502 zinc finger protein 502
ZNF511 zinc finger protein 511
ZNF618 zinc finger protein 618
ZNF621 zinc finger protein 621
ZNF654 zinc finger protein 654
ZNF79 zinc finger protein 79
ZNF860 zinc finger protein 860
ZRANB2 zinc finger, RAN-binding domain containing 2

low expression

Symbol Name
C10ORF76 chromosome 10 open reading frame 76
EXOC4 exocyst complex component 4
MRPL43 mitochondrial ribosomal protein L43
NTPCR nucleoside-triphosphatase, cancer-related