Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6998-01A-23R-2016-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

417 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6998-01A-23R-2016-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABI1 abl-interactor 1
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTG1 actin gamma 1
ACVR1C activin A receptor, type IC
ADAM21P1 ADAM metallopeptidase domain 21 pseudogene 1
AFF4 AF4/FMR2 family, member 4
AGO2 argonaute RISC catalytic component 2
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AGPAT4-IT1 AGPAT4 intronic transcript 1
ALAS1 5'-aminolevulinate synthase 1
ALPP alkaline phosphatase, placental
AMHR2 anti-Mullerian hormone receptor, type II
AMMECR1L AMMECR1-like
ANXA1 annexin A1
AP3D1 adaptor-related protein complex 3, delta 1 subunit
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGAP17 Rho GTPase activating protein 17
ARHGAP21 Rho GTPase activating protein 21
ARHGAP5 Rho GTPase activating protein 5
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ATG12 autophagy related 12
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP11B ATPase, class VI, type 11B
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATXN2 ataxin 2
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
BMP2 bone morphogenetic protein 2
BMP2K BMP2 inducible kinase
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG1 B-cell translocation gene 1, anti-proliferative
BZW1 basic leucine zipper and W2 domains 1
C10ORF99 chromosome 10 open reading frame 99
C11ORF63 chromosome 11 open reading frame 63
C16ORF72 chromosome 16 open reading frame 72
C1ORF177 chromosome 1 open reading frame 177
C20ORF141 chromosome 20 open reading frame 141
C3ORF36 chromosome 3 open reading frame 36
CAB39 calcium binding protein 39
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CATSPERB catsper channel auxiliary subunit beta
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD47 CD47 molecule
CDA cytidine deaminase
CDH16 cadherin 16, KSP-cadherin
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDV3 CDV3 homolog (mouse)
CEACAM19 carcinoembryonic antigen-related cell adhesion molecule 19
CES2 carboxylesterase 2
CHD1 chromodomain helicase DNA binding protein 1
CHMP4C charged multivesicular body protein 4C
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLCA2 chloride channel accessory 2
CLIP1 CAP-GLY domain containing linker protein 1
CLTC clathrin, heavy chain (Hc)
CMIP c-Maf inducing protein
CNBP CCHC-type zinc finger, nucleic acid binding protein
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COBLL1 cordon-bleu WH2 repeat protein-like 1
COPB2 coatomer protein complex, subunit beta 2 (beta prime)
COPG1 coatomer protein complex, subunit gamma 1
COQ10B coenzyme Q10 homolog B (S. cerevisiae)
CPEB2 cytoplasmic polyadenylation element binding protein 2
CPEB4 cytoplasmic polyadenylation element binding protein 4
CREB1 cAMP responsive element binding protein 1
CSNK1A1 casein kinase 1, alpha 1
CSNK1A1L casein kinase 1, alpha 1-like
CSTA cystatin A (stefin A)
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
CXCR1 chemokine (C-X-C motif) receptor 1
CYLD cylindromatosis (turban tumor syndrome)
CYP27C1 cytochrome P450, family 27, subfamily C, polypeptide 1
DARS aspartyl-tRNA synthetase
DCAF10 DDB1 and CUL4 associated factor 10
DEFB103B defensin, beta 103B
DENND1B DENN/MADD domain containing 1B
DIAPH1 diaphanous-related formin 1
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5
DSC2 desmocollin 2
DSG3 desmoglein 3
DSP desmoplakin
DTX3L deltex 3 like, E3 ubiquitin ligase
DUSP10 dual specificity phosphatase 10
DUSP14 dual specificity phosphatase 14
DUSP18 dual specificity phosphatase 18
DUSP7 dual specificity phosphatase 7
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
EFR3A EFR3 homolog A (S. cerevisiae)
EHBP1 EH domain binding protein 1
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
EIF3H eukaryotic translation initiation factor 3, subunit H
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ELL2 elongation factor, RNA polymerase II, 2
ENAH enabled homolog (Drosophila)
ENDOD1 endonuclease domain containing 1
ENO1 enolase 1, (alpha)
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
ERO1L ERO1-like (S. cerevisiae)
ESRP1 epithelial splicing regulatory protein 1
EXOC2 exocyst complex component 2
EZR ezrin
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP5P3 fatty acid binding protein 5 pseudogene 3
FAM126B family with sequence similarity 126, member B
FAM49B family with sequence similarity 49, member B
FAM83A family with sequence similarity 83, member A
FAM83G family with sequence similarity 83, member G
FAM83H family with sequence similarity 83, member H
FBLIM1 filamin binding LIM protein 1
FBXO45 F-box protein 45
FBXO6 F-box protein 6
FBXW11 F-box and WD repeat domain containing 11
FEM1C fem-1 homolog c (C. elegans)
FER fer (fps/fes related) tyrosine kinase
FERMT1 fermitin family member 1
FHL2 four and a half LIM domains 2
FLJ23867 uncharacterized protein FLJ23867
FLRT3 fibronectin leucine rich transmembrane protein 3
FMNL2 formin-like 2
FNIP1 folliculin interacting protein 1
FNIP2 folliculin interacting protein 2
FYTTD1 forty-two-three domain containing 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATAD2A GATA zinc finger domain containing 2A
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GID4 GID complex subunit 4
GJB2 gap junction protein, beta 2, 26kDa
GJB3 gap junction protein, beta 3, 31kDa
GJB6 gap junction protein, beta 6, 30kDa
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GOLGA7B golgin A7 family, member B
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HBEGF heparin-binding EGF-like growth factor
HDLBP high density lipoprotein binding protein
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HK2 hexokinase 2
HOMER1 homer scaffolding protein 1
HOMER2 homer scaffolding protein 2
HR hair growth associated
HRH1 histamine receptor H1
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HSF1 heat shock transcription factor 1
HSPH1 heat shock 105kDa/110kDa protein 1
IFIH1 interferon induced with helicase C domain 1
IFNLR1 interferon, lambda receptor 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL1RN interleukin 1 receptor antagonist
IL36RN interleukin 36 receptor antagonist
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1
INO80D INO80 complex subunit D
IRF6 interferon regulatory factor 6
JARID2 jumonji, AT rich interactive domain 2
JUP junction plakoglobin
KALRN kalirin, RhoGEF kinase
KANK1 KN motif and ankyrin repeat domains 1
KCTD10 potassium channel tetramerization domain containing 10
KCTD15 potassium channel tetramerization domain containing 15
KCTD9 potassium channel tetramerization domain containing 9
KDM6B lysine (K)-specific demethylase 6B
KDM7A lysine (K)-specific demethylase 7A
KDSR 3-ketodihydrosphingosine reductase
KIAA0196 KIAA0196
KIF13B kinesin family member 13B
KIF3A kinesin family member 3A
KLF7 Kruppel-like factor 7 (ubiquitous)
KPNA1 karyopherin alpha 1 (importin alpha 5)
KPNA4 karyopherin alpha 4 (importin alpha 3)
LACE1 lactation elevated 1
LAD1 ladinin 1
LARP4 La ribonucleoprotein domain family, member 4
LCMT1 leucine carboxyl methyltransferase 1
LIG4 ligase IV, DNA, ATP-dependent
LINC01559 long intergenic non-protein coding RNA 1559
LNX2 ligand of numb-protein X 2
LOC100132831 A20-binding inhibitor of NF-kappaB activation 2 pseudogene
LPAR3 lysophosphatidic acid receptor 3
LRRC8C leucine rich repeat containing 8 family, member C
LRRC8E leucine rich repeat containing 8 family, member E
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LYNX1 Ly6/neurotoxin 1
LYPD5 LY6/PLAUR domain containing 5
LYST lysosomal trafficking regulator
MACF1 microtubule-actin crosslinking factor 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAP7 microtubule-associated protein 7
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
MAST4 microtubule associated serine/threonine kinase family member 4
MBD1 methyl-CpG binding domain protein 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MFAP3L microfibrillar-associated protein 3-like
MINA MYC induced nuclear antigen
MINK1 misshapen-like kinase 1
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
MSANTD3 Myb/SANT-like DNA-binding domain containing 3
MTDH metadherin
MTMR9 myotubularin related protein 9
MTSS1 metastasis suppressor 1
MXD1 MAX dimerization protein 1
MYO1C myosin IC
NDEL1 nudE neurodevelopment protein 1-like 1
NDRG1 N-myc downstream regulated 1
NEK7 NIMA-related kinase 7
NEU2 sialidase 2 (cytosolic sialidase)
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NGEF neuronal guanine nucleotide exchange factor
NIPAL4 NIPA-like domain containing 4
NOD2 nucleotide-binding oligomerization domain containing 2
NPEPPS aminopeptidase puromycin sensitive
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRBF2 nuclear receptor binding factor 2
NRIP1 nuclear receptor interacting protein 1
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
OPTN optineurin
OR2L13 olfactory receptor, family 2, subfamily L, member 13
OR2T10 olfactory receptor, family 2, subfamily T, member 10
OSBPL11 oxysterol binding protein-like 11
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PAEP progestagen-associated endometrial protein
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PARP14 poly (ADP-ribose) polymerase family, member 14
PARP9 poly (ADP-ribose) polymerase family, member 9
PCDHGA10 protocadherin gamma subfamily A, 10
PCDHGC3 protocadherin gamma subfamily C, 3
PCDHGC5 protocadherin gamma subfamily C, 5
PEA15 phosphoprotein enriched in astrocytes 15
PERP PERP, TP53 apoptosis effector
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PKP1 plakophilin 1
PLA2G3 phospholipase A2, group III
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD2 phospholipase D2
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLEKHM3 pleckstrin homology domain containing, family M, member 3
PLIN3 perilipin 3
PNRC1 proline-rich nuclear receptor coactivator 1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PPARD peroxisome proliferator-activated receptor delta
PPIF peptidylprolyl isomerase F
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRSS53 protease, serine, 53
PTEN phosphatase and tensin homolog
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional)
PTK2 protein tyrosine kinase 2
PYGL phosphorylase, glycogen, liver
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RAB10 RAB10, member RAS oncogene family
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RAB7A RAB7A, member RAS oncogene family
RABL3 RAB, member of RAS oncogene family-like 3
RAET1L retinoic acid early transcript 1L
RALB v-ral simian leukemia viral oncogene homolog B
RAP2B RAP2B, member of RAS oncogene family
RASSF3 Ras association (RalGDS/AF-6) domain family member 3
RB1 retinoblastoma 1
RB1CC1 RB1-inducible coiled-coil 1
RBMS1 RNA binding motif, single stranded interacting protein 1
RCOR1 REST corepressor 1
RFTN1 raftlin, lipid raft linker 1
RGPD5 RANBP2-like and GRIP domain containing 5
RGS20 regulator of G-protein signaling 20
RNF144B ring finger protein 144B
RNF149 ring finger protein 149
RNF19B ring finger protein 19B
RPL7 ribosomal protein L7
RRAGC Ras-related GTP binding C
RSAD2 radical S-adenosyl methionine domain containing 2
RTCA RNA 3'-terminal phosphate cyclase
SCAMP1 secretory carrier membrane protein 1
SCNN1D sodium channel, non voltage gated 1 delta subunit
SCYL2 SCY1-like 2 (S. cerevisiae)
SDC1 syndecan 1
SDCBP2 syndecan binding protein (syntenin) 2
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SEC24A SEC24 family member A
SEPT8 septin 8
SEPT9 septin 9
SERBP1 SERPINE1 mRNA binding protein 1
SERINC3 serine incorporator 3
SERP1 stress-associated endoplasmic reticulum protein 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERTAD2 SERTA domain containing 2
SFN stratifin
SGK223 homolog of rat pragma of Rnd2
SGMS2 sphingomyelin synthase 2
SGPP2 sphingosine-1-phosphate phosphatase 2
SKIL SKI-like proto-oncogene
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC22A23 solute carrier family 22, member 23
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC38A2 solute carrier family 38, member 2
SLC5A10 solute carrier family 5 (sodium/sugar cotransporter), member 10
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLURP1 secreted LY6/PLAUR domain containing 1
SNX16 sorting nexin 16
SNX3 sorting nexin 3
SNX4 sorting nexin 4
SOWAHC sosondowah ankyrin repeat domain family member C
SP1 Sp1 transcription factor
SPAG1 sperm associated antigen 1
SPOPL speckle-type POZ protein-like
SPPL3 signal peptide peptidase like 3
SPRR1B small proline-rich protein 1B
SSFA2 sperm specific antigen 2
STON2 stonin 2
STRIP1 striatin interacting protein 1
STX11 syntaxin 11
STX6 syntaxin 6
SULT1C3 sulfotransferase family, cytosolic, 1C, member 3
SUMO4 small ubiquitin-like modifier 4
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D2 TBC1 domain family, member 2
TBC1D23 TBC1 domain family, member 23
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TBX18 T-box 18
TENM2 teneurin transmembrane protein 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFG TRK-fused gene
TGFA transforming growth factor, alpha
TGM5 transglutaminase 5
TICAM1 toll-like receptor adaptor molecule 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLE4 transducin-like enhancer of split 4
TM4SF1 transmembrane 4 L six family member 1
TM4SF19 transmembrane 4 L six family member 19
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMCC1 transmembrane and coiled-coil domain family 1
TMCC3 transmembrane and coiled-coil domain family 3
TMED7 transmembrane emp24 protein transport domain containing 7
TMEM217 transmembrane protein 217
TMEM33 transmembrane protein 33
TMEM79 transmembrane protein 79
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOR4A torsin family 4, member A
TRAF3IP2 TRAF3 interacting protein 2
TRAM1 translocation associated membrane protein 1
TRIB1 tribbles pseudokinase 1
TRIM23 tripartite motif containing 23
TRIP12 thyroid hormone receptor interactor 12
TRPS1 trichorhinophalangeal syndrome I
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TSC22D2 TSC22 domain family, member 2
TTPAL tocopherol (alpha) transfer protein-like
TUBA4A tubulin, alpha 4a
TUBB2A tubulin, beta 2A class IIa
TWF1 twinfilin actin binding protein 1
UBAP2 ubiquitin associated protein 2
UBE2F ubiquitin-conjugating enzyme E2F (putative)
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1
UBQLN2 ubiquilin 2
UBTD2 ubiquitin domain containing 2
UNC13D unc-13 homolog D (C. elegans)
USP2 ubiquitin specific peptidase 2
USP32 ubiquitin specific peptidase 32
USP43 ubiquitin specific peptidase 43
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VDAC1 voltage-dependent anion channel 1
VIPR1 vasoactive intestinal peptide receptor 1
VTA1 vesicle (multivesicular body) trafficking 1
WDR53 WD repeat domain 53
WIPF2 WAS/WASL interacting protein family, member 2
WNK1 WNK lysine deficient protein kinase 1
XAF1 XIAP associated factor 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRN1 5'-3' exoribonuclease 1
YIPF5 Yip1 domain family, member 5
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBTB11 zinc finger and BTB domain containing 11
ZBTB43 zinc finger and BTB domain containing 43
ZC3H3 zinc finger CCCH-type containing 3
ZFAT-AS1 ZFAT antisense RNA 1
ZHX1 zinc fingers and homeoboxes 1
ZMAT5 zinc finger, matrin-type 5
ZNF148 zinc finger protein 148
ZNF250 zinc finger protein 250
ZNF282 zinc finger protein 282
ZNF385A zinc finger protein 385A

low expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
GPHN gephyrin
IWS1 IWS1 homolog (S. cerevisiae)
SAFB scaffold attachment factor B
SDAD1 SDA1 domain containing 1