Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5366-01A-01R-1436-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

357 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5366-01A-01R-1436-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACTN1 actinin, alpha 1
ACTR10 actin-related protein 10 homolog (S. cerevisiae)
ADAL adenosine deaminase-like
ADAM10 ADAM metallopeptidase domain 10
ADGRF4 adhesion G protein-coupled receptor F4
ADGRG3 adhesion G protein-coupled receptor G3
AHNAK2 AHNAK nucleoprotein 2
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AKAP10 A kinase (PRKA) anchor protein 10
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ANGEL1 angel homolog 1 (Drosophila)
ANTXRL anthrax toxin receptor-like
APP amyloid beta (A4) precursor protein
AQP6 aquaporin 6, kidney specific
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1
ARL4D ADP-ribosylation factor-like 4D
ARMC7 armadillo repeat containing 7
ATG14 autophagy related 14
ATP10D ATPase, class V, type 10D
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATXN3 ataxin 3
BAG5 BCL2-associated athanogene 5
BCAS3 breast carcinoma amplified sequence 3
BDKRB2 bradykinin receptor B2
BTBD7 BTB (POZ) domain containing 7
BTBD8 BTB (POZ) domain containing 8
C11ORF65 chromosome 11 open reading frame 65
C11ORF94 chromosome 11 open reading frame 94
C14ORF1 chromosome 14 open reading frame 1
C14ORF166 chromosome 14 open reading frame 166
C14ORF169 chromosome 14 open reading frame 169
C14ORF79 chromosome 14 open reading frame 79
C17ORF85 chromosome 17 open reading frame 85
C1QTNF6 C1q and tumor necrosis factor related protein 6
C2ORF74 chromosome 2 open reading frame 74
C8ORF37 chromosome 8 open reading frame 37
CATSPER2P1 cation channel, sperm associated 2 pseudogene 1
CCDC102B coiled-coil domain containing 102B
CCDC127 coiled-coil domain containing 127
CCDC43 coiled-coil domain containing 43
CCDC63 coiled-coil domain containing 63
CCNK cyclin K
CD109 CD109 molecule
CD276 CD276 molecule
CDC27 cell division cycle 27
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CEP170B centrosomal protein 170B
CLCN6 chloride channel, voltage-sensitive 6
CLSTN1 calsyntenin 1
CLTC clathrin, heavy chain (Hc)
COL27A1 collagen, type XXVII, alpha 1
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CXCR1 chemokine (C-X-C motif) receptor 1
CXORF56 chromosome X open reading frame 56
DCAF4 DDB1 and CUL4 associated factor 4
DCAF5 DDB1 and CUL4 associated factor 5
DCAF7 DDB1 and CUL4 associated factor 7
DCBLD2 discoidin, CUB and LCCL domain containing 2
DCTN1 dynactin 1
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DHFRL1 dihydrofolate reductase-like 1
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11
DNM3 dynamin 3
DRD5 dopamine receptor D5
DRG2 developmentally regulated GTP binding protein 2
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EBAG9 estrogen receptor binding site associated, antigen, 9
EFTUD2 elongation factor Tu GTP binding domain containing 2
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EXD2 exonuclease 3'-5' domain containing 2
FAM149B1 family with sequence similarity 149, member B1
FAM171A2 family with sequence similarity 171, member A2
FAM179B family with sequence similarity 179, member B
FAM58BP cyclin-related protein FAM58B
FAM86C1 family with sequence similarity 86, member C1
FANCM Fanconi anemia, complementation group M
FBXO39 F-box protein 39
FCF1 FCF1 rRNA-processing protein
FKBP3 FK506 binding protein 3, 25kDa
FKRP fukutin related protein
FLII flightless I homolog (Drosophila)
FLJ36777 uncharacterized LOC730971
FLRT2 fibronectin leucine rich transmembrane protein 2
FLT4 fms-related tyrosine kinase 4
FNTB farnesyltransferase, CAAX box, beta
FRMD6 FERM domain containing 6
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
FYB FYN binding protein
FZD2 frizzled class receptor 2
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GGCX gamma-glutamyl carboxylase
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GOLGA5 golgin A5
GOLGA7B golgin A7 family, member B
GOSR2 golgi SNAP receptor complex member 2
GPATCH2L G patch domain containing 2-like
GPR182 G protein-coupled receptor 182
GRAMD2 GRAM domain containing 2
GSTZ1 glutathione S-transferase zeta 1
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HACD4 3-hydroxyacyl-CoA dehydratase 4
HBZ hemoglobin, zeta
HEATR6 HEAT repeat containing 6
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HFE hemochromatosis
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BI histone cluster 1, H2bi
HIST1H2BL histone cluster 1, H2bl
HIST1H3H histone cluster 1, H3h
HIST1H4D histone cluster 1, H4d
HOXC5 homeobox C5
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IARS isoleucyl-tRNA synthetase
ICMT isoprenylcysteine carboxyl methyltransferase
INHBC inhibin, beta C
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
INSL3 insulin-like 3 (Leydig cell)
INTS2 integrator complex subunit 2
ISCA2 iron-sulfur cluster assembly 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGB4 integrin, beta 4
IVD isovaleryl-CoA dehydrogenase
IVNS1ABP influenza virus NS1A binding protein
JAG2 jagged 2
JKAMP JNK1/MAPK8-associated membrane protein
KCTD2 potassium channel tetramerization domain containing 2
KIAA0196 KIAA0196
KIAA0391 KIAA0391
KIAA0586 KIAA0586
KIAA1107 KIAA1107
KIAA1429 KIAA1429
KIF13A kinesin family member 13A
KLC1 kinesin light chain 1
KLHL4 kelch-like family member 4
KPNB1 karyopherin (importin) beta 1
KTN1 kinectin 1 (kinesin receptor)
KTN1-AS1 KTN1 antisense RNA 1
LAMA3 laminin, alpha 3
LAMC2 laminin, gamma 2
LARP6 La ribonucleoprotein domain family, member 6
LIN52 lin-52 DREAM MuvB core complex component
LIPG lipase, endothelial
LOC152225 uncharacterized LOC152225
LOC283332 uncharacterized LOC283332
LOC401010 nucleolar complex associated 2 homolog (S. cerevisiae) pseudogene
LOC642852 uncharacterized LOC642852
LPCAT1 lysophosphatidylcholine acyltransferase 1
LPCAT2 lysophosphatidylcholine acyltransferase 2
LRRC47 leucine rich repeat containing 47
LRRC49 leucine rich repeat containing 49
LRRC59 leucine rich repeat containing 59
LTBP1 latent transforming growth factor beta binding protein 1
LZIC leucine zipper and CTNNBIP1 domain containing
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MARK3 MAP/microtubule affinity-regulating kinase 3
MED6 mediator complex subunit 6
MESDC2 mesoderm development candidate 2
METTL16 methyltransferase like 16
MFAP1 microfibrillar-associated protein 1
MFSD11 major facilitator superfamily domain containing 11
MGC16275 uncharacterized protein MGC16275
MGC45800
MLH3 mutL homolog 3
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MN1 meningioma (disrupted in balanced translocation) 1
MNAT1 MNAT CDK-activating kinase assembly factor 1
MPI mannose phosphate isomerase
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MSN moesin
MTA1 metastasis associated 1
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYO1C myosin IC
MYO3B myosin IIIB
MYOF myoferlin
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit
NAPSA napsin A aspartic peptidase
NAV3 neuron navigator 3
NEK9 NIMA-related kinase 9
NELL2 NEL-like 2 (chicken)
NEMF nuclear export mediator factor
NEUROG3 neurogenin 3
NFE2L1 nuclear factor, erythroid 2-like 1
NMNAT1 nicotinamide nucleotide adenylyltransferase 1
NMT1 N-myristoyltransferase 1
NOL9 nucleolar protein 9
NOXRED1 NADP-dependent oxidoreductase domain containing 1
NPC2 Niemann-Pick disease, type C2
NPY4R neuropeptide Y receptor Y4
NRDE2 NRDE-2, necessary for RNA interference, domain containing
ODF3L1 outer dense fiber of sperm tails 3-like 1
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4
OR51V1 olfactory receptor, family 51, subfamily V, member 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PAEP progestagen-associated endometrial protein
PAPLN papilin, proteoglycan-like sulfated glycoprotein
PAPOLA poly(A) polymerase alpha
PAQR4 progestin and adipoQ receptor family member IV
PCDHGA10 protocadherin gamma subfamily A, 10
PCDHGB6 protocadherin gamma subfamily B, 6
PCNX pecanex homolog (Drosophila)
PCSK9 proprotein convertase subtilisin/kexin type 9
PEX10 peroxisomal biogenesis factor 10
PEX12 peroxisomal biogenesis factor 12
PEX26 peroxisomal biogenesis factor 26
PGS1 phosphatidylglycerophosphate synthase 1
PI15 peptidase inhibitor 15
PLAU plasminogen activator, urokinase
PLBD2 phospholipase B domain containing 2
PLEK2 pleckstrin 2
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
PNMA1 paraneoplastic Ma antigen 1
PNPO pyridoxamine 5'-phosphate oxidase
POMT2 protein-O-mannosyltransferase 2
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PPP4R4 protein phosphatase 4, regulatory subunit 4
PQLC3 PQ loop repeat containing 3
PRKG1 protein kinase, cGMP-dependent, type I
PRNP prion protein
PSEN1 presenilin 1
PTCD3 pentatricopeptide repeat domain 3
PTK7 protein tyrosine kinase 7 (inactive)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTRF polymerase I and transcript release factor
PYGL phosphorylase, glycogen, liver
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RFX7 regulatory factor X, 7
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF167 ring finger protein 167
RTKN rhotekin
RTN4RL1 reticulon 4 receptor-like 1
RUNX1-IT1 RUNX1 intronic transcript 1
RWDD2B RWD domain containing 2B
RXFP3 relaxin/insulin-like family peptide receptor 3
SAMD15 sterile alpha motif domain containing 15
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SETD3 SET domain containing 3
SFTPA1 surfactant protein A1
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SLC16A13 solute carrier family 16, member 13
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC2A7 solute carrier family 2 (facilitated glucose transporter), member 7
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4
SLC35F6 solute carrier family 35, member F6
SLC38A7 solute carrier family 38, member 7
SLC39A9 solute carrier family 39, member 9
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLFN12 schlafen family member 12
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNW1 SNW domain containing 1
SNX11 sorting nexin 11
SOCS4 suppressor of cytokine signaling 4
SOS2 son of sevenless homolog 2 (Drosophila)
SOX15 SRY (sex determining region Y)-box 15
SPATA20 spermatogenesis associated 20
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRBD1 S1 RNA binding domain 1
SRP54 signal recognition particle 54kDa
SRPX sushi-repeat containing protein, X-linked
SRR serine racemase
STON2 stonin 2
STXBP4 syntaxin binding protein 4
SULF2 sulfatase 2
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like
SUSD6 sushi domain containing 6
SYNE2 spectrin repeat containing, nuclear envelope 2
SYNJ2BP synaptojanin 2 binding protein
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D2B TBC1 domain family, member 2B
TBC1D3P2 TBC1 domain family, member 3 pseudogene 2
TCTA T-cell leukemia translocation altered
TDP1 tyrosyl-DNA phosphodiesterase 1
TECPR2 tectonin beta-propeller repeat containing 2
TEX261 testis expressed 261
THADA thyroid adenoma associated
TLE6 transducin-like enhancer of split 6
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMED10P1 transmembrane emp24-like trafficking protein 10 (yeast) pseudogene 1
TMEM131 transmembrane protein 131
TMEM184B transmembrane protein 184B
TMEM251 transmembrane protein 251
TMEM26 transmembrane protein 26
TMEM60 transmembrane protein 60
TMEM67 transmembrane protein 67
TMEM87A transmembrane protein 87A
TMEM87B transmembrane protein 87B
TMUB2 transmembrane and ubiquitin-like domain containing 2
TMX1 thioredoxin-related transmembrane protein 1
TNC tenascin C
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TOP3A topoisomerase (DNA) III alpha
TPMT thiopurine S-methyltransferase
TRAPPC6B trafficking protein particle complex 6B
TRIM65 tripartite motif containing 65
TRIP11 thyroid hormone receptor interactor 11
TRMT5 tRNA methyltransferase 5
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TTC8 tetratricopeptide repeat domain 8
TTLL5 tubulin tyrosine ligase-like family member 5
TTPAL tocopherol (alpha) transfer protein-like
TTYH2 tweety family member 2
TUG1 taurine up-regulated 1 (non-protein coding)
UBE2Z ubiquitin-conjugating enzyme E2Z
UBTF upstream binding transcription factor, RNA polymerase I
ULBP3 UL16 binding protein 3
USP40 ubiquitin specific peptidase 40
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae)
VTI1B vesicle transport through interaction with t-SNAREs 1B
VWA9 von Willebrand factor A domain containing 9
WDHD1 WD repeat and HMG-box DNA binding protein 1
WDR89 WD repeat domain 89
WFDC11 WAP four-disulfide core domain 11
WNT7A wingless-type MMTV integration site family, member 7A
XYLT2 xylosyltransferase II
YLPM1 YLP motif containing 1
YY1 YY1 transcription factor
ZBTB1 zinc finger and BTB domain containing 1
ZBTB25 zinc finger and BTB domain containing 25
ZC3H14 zinc finger CCCH-type containing 14
ZFAT-AS1 ZFAT antisense RNA 1
ZFYVE1 zinc finger, FYVE domain containing 1
ZFYVE21 zinc finger, FYVE domain containing 21
ZFYVE26 zinc finger, FYVE domain containing 26
ZNF286A zinc finger protein 286A
ZNF410 zinc finger protein 410
ZNF425 zinc finger protein 425
ZNF624 zinc finger protein 624
ZNF70 zinc finger protein 70

low expression

Symbol Name
TMLHE trimethyllysine hydroxylase, epsilon
ZFP69 ZFP69 zinc finger protein