Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5364-01A-01R-1436-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

339 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5364-01A-01R-1436-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACER3 alkaline ceramidase 3
ACP1 acid phosphatase 1, soluble
ADAM17 ADAM metallopeptidase domain 17
ADCY3 adenylate cyclase 3
ADRBK1 adrenergic, beta, receptor kinase 1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALG1L2 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2
ANAPC5 anaphase promoting complex subunit 5
ANKDD1A ankyrin repeat and death domain containing 1A
ANO1 anoctamin 1, calcium activated chloride channel
ANXA8L1 annexin A8-like 1
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP3B1 adaptor-related protein complex 3, beta 1 subunit
ARHGAP10 Rho GTPase activating protein 10
ARHGAP35 Rho GTPase activating protein 35
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARL2 ADP-ribosylation factor-like 2
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ARMS2 age-related maculopathy susceptibility 2
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATR ATR serine/threonine kinase
BANF1 barrier to autointegration factor 1
BBS1 Bardet-Biedl syndrome 1
BDKRB1 bradykinin receptor B1
BID BH3 interacting domain death agonist
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C10ORF11 chromosome 10 open reading frame 11
C10ORF76 chromosome 10 open reading frame 76
C11ORF45 chromosome 11 open reading frame 45
C11ORF68 chromosome 11 open reading frame 68
C2ORF44 chromosome 2 open reading frame 44
C2ORF48 chromosome 2 open reading frame 48
CA12 carbonic anhydrase XII
CALML3 calmodulin-like 3
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CAPN1 calpain 1, (mu/I) large subunit
CAPN2 calpain 2, (m/II) large subunit
CASC5 cancer susceptibility candidate 5
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCDC87 coiled-coil domain containing 87
CCNB1 cyclin B1
CD1C CD1c molecule
CD47 CD47 molecule
CDCA2 cell division cycle associated 2
CDCA5 cell division cycle associated 5
CDCA7L cell division cycle associated 7-like
CDCA8 cell division cycle associated 8
CDH17 cadherin 17, LI cadherin (liver-intestine)
CENPF centromere protein F, 350/400kDa
CENPN centromere protein N
CENPO centromere protein O
CENPW centromere protein W
CFL1 cofilin 1 (non-muscle)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CKAP2L cytoskeleton associated protein 2-like
CLDN22 claudin 22
CLSTN1 calsyntenin 1
COBLL1 cordon-bleu WH2 repeat protein-like 1
CORO1B coronin, actin binding protein, 1B
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa
CREG2 cellular repressor of E1A-stimulated genes 2
CRTAC1 cartilage acidic protein 1
CRYBB1 crystallin, beta B1
CYMP chymosin pseudogene
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DAPL1 death associated protein-like 1
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DEFB104A defensin, beta 104A
DEPDC7 DEP domain containing 7
DGKG diacylglycerol kinase, gamma 90kDa
DHRS3 dehydrogenase/reductase (SDR family) member 3
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DLG1 discs, large homolog 1 (Drosophila)
DLG5 discs, large homolog 5 (Drosophila)
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNASE1L3 deoxyribonuclease I-like 3
DPF2 D4, zinc and double PHD fingers family 2
DPP3 dipeptidyl-peptidase 3
DRAM2 DNA-damage regulated autophagy modulator 2
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
DRD5 dopamine receptor D5
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFHD2 EF-hand domain family, member D2
EIF1AD eukaryotic translation initiation factor 1A domain containing
EPHA7 EPH receptor A7
EPHB1 EPH receptor B1
ERLIN1 ER lipid raft associated 1
FABP12 fatty acid binding protein 12
FAM117B family with sequence similarity 117, member B
FAM138E family with sequence similarity 138, member E
FAM138F family with sequence similarity 138, member F
FAM19A3 family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
FAM20A family with sequence similarity 20, member A
FAM90A7P putative protein FAM90A7
FAT1 FAT atypical cadherin 1
FAT2 FAT atypical cadherin 2
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
FBXO36 F-box protein 36
FGD6 FYVE, RhoGEF and PH domain containing 6
FGF1 fibroblast growth factor 1 (acidic)
FHAD1 forkhead-associated (FHA) phosphopeptide binding domain 1
FIBP fibroblast growth factor (acidic) intracellular binding protein
FOXP2 forkhead box P2
FRMD8 FERM domain containing 8
GAPVD1 GTPase activating protein and VPS9 domains 1
GDF2 growth differentiation factor 2
GEN1 GEN1 Holliday junction 5' flap endonuclease
GLE1 GLE1 RNA export mediator
GMPS guanine monphosphate synthase
GPR20 G protein-coupled receptor 20
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
GSTP1 glutathione S-transferase pi 1
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HDAC1 histone deacetylase 1
HDGF hepatoma-derived growth factor
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HNRNPR heterogeneous nuclear ribonucleoprotein R
HS6ST2 heparan sulfate 6-O-sulfotransferase 2
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
IFNA21 interferon, alpha 21
IGSF3 immunoglobulin superfamily, member 3
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein-like 2
KAT5 K(lysine) acetyltransferase 5
KCNK10 potassium channel, two pore domain subfamily K, member 10
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDM2A lysine (K)-specific demethylase 2A
KIAA1217 KIAA1217
KIAA1522 KIAA1522
KIDINS220 kinase D-interacting substrate, 220kDa
KIF11 kinesin family member 11
KIF16B kinesin family member 16B
KIF20A kinesin family member 20A
KIF20B kinesin family member 20B
KIF6 kinesin family member 6
KLC2 kinesin light chain 2
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LDAH lipid droplet associated hydrolase
LGI3 leucine-rich repeat LGI family, member 3
LINC00304 long intergenic non-protein coding RNA 304
LMNB2 lamin B2
LOC341056 SUMO1 activating enzyme subunit 1 pseudogene
LRP5 low density lipoprotein receptor-related protein 5
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAPK10 mitogen-activated protein kinase 10
MAPKAP1 mitogen-activated protein kinase associated protein 1
MBNL1 muscleblind-like splicing regulator 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MCM2 minichromosome maintenance complex component 2
MCM6 minichromosome maintenance complex component 6
MCTP2 multiple C2 domains, transmembrane 2
METAP1 methionyl aminopeptidase 1
MKI67 marker of proliferation Ki-67
MORC2-AS1 MORC2 antisense RNA 1
MPPED2 metallophosphoesterase domain containing 2
MRPL11 mitochondrial ribosomal protein L11
MRPL49 mitochondrial ribosomal protein L49
MTUS1 microtubule associated tumor suppressor 1
MUS81 MUS81 structure-specific endonuclease subunit
NBPF22P neuroblastoma breakpoint family, member 22, pseudogene
NCAPH non-SMC condensin I complex, subunit H
NCEH1 neutral cholesterol ester hydrolase 1
NCK2 NCK adaptor protein 2
NCKAP5 NCK-associated protein 5
NCL nucleolin
NCR2 natural cytotoxicity triggering receptor 2
NEFM neurofilament, medium polypeptide
NET1 neuroepithelial cell transforming 1
NFIA nuclear factor I/A
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NINJ2 ninjurin 2
NOL10 nucleolar protein 10
NPNT nephronectin
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUP62 nucleoporin 62kDa
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
OAT ornithine aminotransferase
OLFML2A olfactomedin-like 2A
OR13F1 olfactory receptor, family 13, subfamily F, member 1
OR1L3 olfactory receptor, family 1, subfamily L, member 3
OR1L8 olfactory receptor, family 1, subfamily L, member 8
OR2A12 olfactory receptor, family 2, subfamily A, member 12
OR51F1 olfactory receptor, family 51, subfamily F, member 1 (gene/pseudogene)
ORC1 origin recognition complex, subunit 1
P3H2 prolyl 3-hydroxylase 2
PACS1 phosphofurin acidic cluster sorting protein 1
PARP4 poly (ADP-ribose) polymerase family, member 4
PC pyruvate carboxylase
PCDHGB2 protocadherin gamma subfamily B, 2
PCDHGC4 protocadherin gamma subfamily C, 4
PCNXL3 pecanex-like 3 (Drosophila)
PDLIM1 PDZ and LIM domain 1
PDZRN3 PDZ domain containing ring finger 3
PELI3 pellino E3 ubiquitin protein ligase family member 3
PER3 period circadian clock 3
PGLYRP3 peptidoglycan recognition protein 3
PIGX phosphatidylinositol glycan anchor biosynthesis, class X
PITX2 paired-like homeodomain 2
PKNOX1 PBX/knotted 1 homeobox 1
PLAT plasminogen activator, tissue
PLD1 phospholipase D1, phosphatidylcholine-specific
PLSCR5 phospholipid scramblase family, member 5
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRC1 protein regulator of cytokinesis 1
PRIMA1 proline rich membrane anchor 1
PRR11 proline rich 11
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSD3 pleckstrin and Sec7 domain containing 3
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSPC1 paraspeckle component 1
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RAB1B RAB1B, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RABL3 RAB, member of RAS oncogene family-like 3
RACGAP1 Rac GTPase activating protein 1
RAD9A RAD9 homolog A (S. pombe)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RASGEF1B RasGEF domain family, member 1B
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
RBL1 retinoblastoma-like 1
RBM4 RNA binding motif protein 4
RBP1 retinol binding protein 1, cellular
REEP4 receptor accessory protein 4
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RHAG Rh-associated glycoprotein
RNASEH1 ribonuclease H1
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RRM1 ribonucleotide reductase M1
SAE1 SUMO1 activating enzyme subunit 1
SAMD12 sterile alpha motif domain containing 12
SART1 squamous cell carcinoma antigen recognized by T cells
SCYL1 SCY1-like 1 (S. cerevisiae)
SERPINA13P serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 13, pseudogene
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SF3B2 splicing factor 3b, subunit 2, 145kDa
SFXN5 sideroflexin 5
SH3RF2 SH3 domain containing ring finger 2
SH3YL1 SH3 and SYLF domain containing 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIK3 SIK family kinase 3
SIPA1 signal-induced proliferation-associated 1
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
SLTM SAFB-like, transcription modulator
SMAD1 SMAD family member 1
SMAD3 SMAD family member 3
SMAD5 SMAD family member 5
SMC3 structural maintenance of chromosomes 3
SMC4 structural maintenance of chromosomes 4
SMC6 structural maintenance of chromosomes 6
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SNORA71A small nucleolar RNA, H/ACA box 71A
SNX15 sorting nexin 15
SNX17 sorting nexin 17
SNX5 sorting nexin 5
SPATA19 spermatogenesis associated 19
SSH3 slingshot protein phosphatase 3
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STIL SCL/TAL1 interrupting locus
STON1-GTF2A1L STON1-GTF2A1L readthrough
STRA6 stimulated by retinoic acid 6
SUN2 Sad1 and UNC84 domain containing 2
SUSD6 sushi domain containing 6
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
SYNJ2 synaptojanin 2
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
TBC1D3P2 TBC1 domain family, member 3 pseudogene 2
TCAF1 TRPM8 channel-associated factor 1
TCERG1 transcription elongation regulator 1
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TGM4 transglutaminase 4
THRAP3 thyroid hormone receptor associated protein 3
TICRR TOPBP1-interacting checkpoint and replication regulator
TM4SF4 transmembrane 4 L six family member 4
TMEM134 transmembrane protein 134
TMEM37 transmembrane protein 37
TMPRSS11A transmembrane protease, serine 11A
TMPRSS11D transmembrane protease, serine 11D
TMPRSS4 transmembrane protease, serine 4
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TRAF3IP2 TRAF3 interacting protein 2
TSG1 tumor suppressor TSG1
TSSC1 tumor suppressing subtransferable candidate 1
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
UBTFL1 upstream binding transcription factor, RNA polymerase I-like 1
UNC93B1 unc-93 homolog B1 (C. elegans)
UST uronyl-2-sulfotransferase
UTS2 urotensin 2
VLDLR very low density lipoprotein receptor
WDR77 WD repeat domain 77
WLS wntless Wnt ligand secretion mediator
WTAP Wilms tumor 1 associated protein
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
YARS tyrosyl-tRNA synthetase
YIF1A Yip1 interacting factor homolog A (S. cerevisiae)
YTHDC1 YTH domain containing 1
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZC3H12C zinc finger CCCH-type containing 12C
ZFPL1 zinc finger protein-like 1
ZNF112 zinc finger protein 112
ZNF134 zinc finger protein 134
ZNF17 zinc finger protein 17
ZNF175 zinc finger protein 175
ZNF264 zinc finger protein 264
ZNF304 zinc finger protein 304
ZNF395 zinc finger protein 395
ZNF436 zinc finger protein 436
ZNF536 zinc finger protein 536
ZNF543 zinc finger protein 543
ZNF551 zinc finger protein 551
ZNF584 zinc finger protein 584
ZNF586 zinc finger protein 586
ZNF587 zinc finger protein 587
ZNF749 zinc finger protein 749
ZNF776 zinc finger protein 776
ZNF845 zinc finger protein 845
ZSCAN5A zinc finger and SCAN domain containing 5A
ZW10 zw10 kinetochore protein

low expression

Symbol Name
BAG6 BCL2-associated athanogene 6
MOB1B MOB kinase activator 1B