Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5363-01A-01R-1436-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

386 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5363-01A-01R-1436-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAED1 AhpC/TSA antioxidant enzyme domain containing 1
ABHD5 abhydrolase domain containing 5
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACER2 alkaline ceramidase 2
ACSL3 acyl-CoA synthetase long-chain family member 3
ACSL4 acyl-CoA synthetase long-chain family member 4
AFF1 AF4/FMR2 family, member 1
AJUBA ajuba LIM protein
AK3 adenylate kinase 3
AKAP2 A kinase (PRKA) anchor protein 2
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ANKRD26P1 ankyrin repeat domain 26 pseudogene 1
ANO6 anoctamin 6
ANXA5 annexin A5
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APOL4 apolipoprotein L, 4
APOL6 apolipoprotein L, 6
ARMT1 acidic residue methyltransferase 1
ARSK arylsulfatase family, member K
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3
AUNIP aurora kinase A and ninein interacting protein
AURKA aurora kinase A
AURKAPS1 aurora kinase A pseudogene 1
BBS12 Bardet-Biedl syndrome 12
BBX bobby sox homolog (Drosophila)
BEND6 BEN domain containing 6
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted
BMS1 BMS1 ribosome biogenesis factor
C1R complement component 1, r subcomponent
C1S complement component 1, s subcomponent
C9ORF72 chromosome 9 open reading frame 72
CAAP1 caspase activity and apoptosis inhibitor 1
CALCOCO2 calcium binding and coiled-coil domain 2
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CALU calumenin
CANX calnexin
CAPRIN1 cell cycle associated protein 1
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC171 coiled-coil domain containing 171
CCDC63 coiled-coil domain containing 63
CCDC91 coiled-coil domain containing 91
CCNA2 cyclin A2
CCP110 centriolar coiled coil protein 110kDa
CCR9 chemokine (C-C motif) receptor 9
CD44 CD44 molecule (Indian blood group)
CDC25C cell division cycle 25C
CDC27 cell division cycle 27
CDC37L1 cell division cycle 37-like 1
CDCA8 cell division cycle associated 8
CDH10 cadherin 10, type 2 (T2-cadherin)
CDH22 cadherin 22, type 2
CDH9 cadherin 9, type 2 (T1-cadherin)
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CENPL centromere protein L
CEP128 centrosomal protein 128kDa
CEP41 centrosomal protein 41kDa
CHD5 chromodomain helicase DNA binding protein 5
CKAP5 cytoskeleton associated protein 5
CLEC2A C-type lectin domain family 2, member A
CLIC4 chloride intracellular channel 4
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNOT6 CCR4-NOT transcription complex, subunit 6
COL17A1 collagen, type XVII, alpha 1
COL18A1 collagen, type XVIII, alpha 1
COMMD9 COMM domain containing 9
COPS8 COP9 signalosome subunit 8
CRYBG3 beta-gamma crystallin domain containing 3
CSF1 colony stimulating factor 1 (macrophage)
CTTN cortactin
CUX1 cut-like homeobox 1
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
DACT1 dishevelled-binding antagonist of beta-catenin 1
DBF4 DBF4 zinc finger
DBF4B DBF4 zinc finger B
DCLK3 doublecortin-like kinase 3
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DEC1 deleted in esophageal cancer 1
DENND4C DENN/MADD domain containing 4C
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DLL1 delta-like 1 (Drosophila)
DLX4 distal-less homeobox 4
DNAJC25-GNG10 DNAJC25-GNG10 readthrough
DTX3L deltex 3 like, E3 ubiquitin ligase
DVL2 dishevelled segment polarity protein 2
ECI2 enoyl-CoA delta isomerase 2
EGLN3 egl-9 family hypoxia-inducible factor 3
EHD2 EH-domain containing 2
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPHB2 EPH receptor B2
ERLIN1 ER lipid raft associated 1
F2R coagulation factor II (thrombin) receptor
FADD Fas (TNFRSF6)-associated via death domain
FAF2 Fas associated factor family member 2
FAM35BP family with sequence similarity 35, member A pseudogene
FBXO5 F-box protein 5
FGFR1OP FGFR1 oncogene partner
FIGN fidgetin
FJX1 four jointed box 1 (Drosophila)
FKBP5 FK506 binding protein 5
FNIP1 folliculin interacting protein 1
FOCAD focadhesin
FOXM1 forkhead box M1
FOXO3 forkhead box O3
FOXO3B forkhead box O3B pseudogene
FZD2 frizzled class receptor 2
G2E3 G2/M-phase specific E3 ubiquitin protein ligase
GANAB glucosidase, alpha; neutral AB
GBP1 guanylate binding protein 1, interferon-inducible
GBP5 guanylate binding protein 5
GCC1 GRIP and coiled-coil domain containing 1
GLUL glutamate-ammonia ligase
GOPC golgi-associated PDZ and coiled-coil motif containing
GPSM2 G-protein signaling modulator 2
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTSE1 G-2 and S-phase expressed 1
HACD2 3-hydroxyacyl-CoA dehydratase 2
HAUS6 HAUS augmin-like complex, subunit 6
HELZ helicase with zinc finger
HIST1H2BH histone cluster 1, H2bh
HIST1H3F histone cluster 1, H3f
HIST1H3I histone cluster 1, H3i
HIST1H4J histone cluster 1, H4j
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HMGB2 high mobility group box 2
HMMR hyaluronan-mediated motility receptor (RHAMM)
HNRNPF heterogeneous nuclear ribonucleoprotein F
HOXC11 homeobox C11
HRH1 histamine receptor H1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSP90B3P heat shock protein 90kDa beta (Grp94), member 3, pseudogene
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IFNGR1 interferon gamma receptor 1
IFNK interferon, kappa
IFT74 intraflagellar transport 74
IGFBP7 insulin-like growth factor binding protein 7
IGHMBP2 immunoglobulin mu binding protein 2
IL12RB2 interleukin 12 receptor, beta 2
IL15 interleukin 15
IL6R interleukin 6 receptor
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INVS inversin
IPMK inositol polyphosphate multikinase
IRX1 iroquois homeobox 1
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB4 integrin, beta 4
JAK2 Janus kinase 2
JDP2 Jun dimerization protein 2
KDM4C lysine (K)-specific demethylase 4C
KGFLP1 fibroblast growth factor 7 pseudogene
KIAA0922 KIAA0922
KIAA1143 KIAA1143
KIAA1191 KIAA1191
KIAA1429 KIAA1429
KIAA2026 KIAA2026
KIF15 kinesin family member 15
KIF20A kinesin family member 20A
KLF9 Kruppel-like factor 9
KLHDC10 kelch domain containing 10
KTN1 kinectin 1 (kinesin receptor)
L3HYPDH L-3-hydroxyproline dehydratase (trans-)
LAMB1 laminin, beta 1
LDLRAD3 low density lipoprotein receptor class A domain containing 3
LHX6 LIM homeobox 6
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
LIMK1 LIM domain kinase 1
LINC00305 long intergenic non-protein coding RNA 305
LINC01555 long intergenic non-protein coding RNA 1555
LOC100129034 uncharacterized LOC100129034
LOX lysyl oxidase
LPCAT1 lysophosphatidylcholine acyltransferase 1
LPPR4 lipid phosphate phosphatase-related protein type 4
LRP11 low density lipoprotein receptor-related protein 11
LRP1B low density lipoprotein receptor-related protein 1B
LRRC19 leucine rich repeat containing 19
LTBP1 latent transforming growth factor beta binding protein 1
MAML1 mastermind-like 1 (Drosophila)
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAPK9 mitogen-activated protein kinase 9
MED23 mediator complex subunit 23
MET MET proto-oncogene, receptor tyrosine kinase
METTL12 methyltransferase like 12
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MICB MHC class I polypeptide-related sequence B
MINPP1 multiple inositol-polyphosphate phosphatase 1
MKI67 marker of proliferation Ki-67
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MOB3B MOB kinase activator 3B
MRPL18 mitochondrial ribosomal protein L18
MSC musculin
MSN moesin
MT1E metallothionein 1E
MT1X metallothionein 1X
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
NAT10 N-acetyltransferase 10 (GCN5-related)
NCOA3 nuclear receptor coactivator 3
NCOA7 nuclear receptor coactivator 7
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NEK6 NIMA-related kinase 6
NFIB nuclear factor I/B
NUP43 nucleoporin 43kDa
OPN3 opsin 3
OR1D4 olfactory receptor, family 1, subfamily D, member 4 (gene/pseudogene)
OR52K2 olfactory receptor, family 52, subfamily K, member 2
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PALM2-AKAP2 PALM2-AKAP2 readthrough
PAPOLA poly(A) polymerase alpha
PARP14 poly (ADP-ribose) polymerase family, member 14
PCBP3 poly(rC) binding protein 3
PCDH10 protocadherin 10
PCGF5 polycomb group ring finger 5
PDE7A phosphodiesterase 7A
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PGBD3 piggyBac transposable element derived 3
PHLDB1 pleckstrin homology-like domain, family B, member 1
PI15 peptidase inhibitor 15
PIAS1 protein inhibitor of activated STAT, 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLAA phospholipase A2-activating protein
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PLK4 polo-like kinase 4
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PMFBP1 polyamine modulated factor 1 binding protein 1
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPID peptidylprolyl isomerase D
PPIL4 peptidylprolyl isomerase (cyclophilin)-like 4
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSIP1 PC4 and SFRS1 interacting protein 1
PSRC1 proline/serine-rich coiled-coil 1
PTCHD2 patched domain containing 2
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional)
PTPRK protein tyrosine phosphatase, receptor type, K
RACGAP1 Rac GTPase activating protein 1
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RANBP6 RAN binding protein 6
RAP1GAP2 RAP1 GTPase activating protein 2
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RB1CC1 RB1-inducible coiled-coil 1
RBM15 RNA binding motif protein 15
RBM18 RNA binding motif protein 18
RBM28 RNA binding motif protein 28
RCL1 RNA terminal phosphate cyclase-like 1
REPS2 RALBP1 associated Eps domain containing 2
RIC1 RAB6A GEF complex partner 1
RNF44 ring finger protein 44
RPL7 ribosomal protein L7
RPS6 ribosomal protein S6
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RRAGA Ras-related GTP binding A
RTN4RL2 reticulon 4 receptor-like 2
RUFY1 RUN and FYVE domain containing 1
SAMD4A sterile alpha motif domain containing 4A
SAP30 Sin3A-associated protein, 30kDa
SERPINA13P serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 13, pseudogene
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SERTAD4 SERTA domain containing 4
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SND1 staphylococcal nuclease and tudor domain containing 1
SNORA44 small nucleolar RNA, H/ACA box 44
SOX12 SRY (sex determining region Y)-box 12
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPOP speckle-type POZ protein
SRPX sushi-repeat containing protein, X-linked
STARD13 StAR-related lipid transfer (START) domain containing 13
STOM stomatin
SUMO4 small ubiquitin-like modifier 4
SYNE2 spectrin repeat containing, nuclear envelope 2
SYNE3 spectrin repeat containing, nuclear envelope family member 3
TBC1D3P1-DHX40P1 TBC1D3P1-DHX40P1 readthrough transcribed pseudogene
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBCK TBC1 domain containing kinase
TBP TATA box binding protein
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TCP1 t-complex 1
TEX2 testis expressed 2
TFCP2L1 transcription factor CP2-like 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGS1 trimethylguanosine synthase 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TLE4 transducin-like enhancer of split 4
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMED7-TICAM2 TMED7-TICAM2 readthrough
TMEM2 transmembrane protein 2
TMEM209 transmembrane protein 209
TMEM242 transmembrane protein 242
TMEM261 transmembrane protein 261
TMEM52B transmembrane protein 52B
TNC tenascin C
TNK1 tyrosine kinase, non-receptor, 1
TNPO1 transportin 1
TNPO3 transportin 3
TNRC6B trinucleotide repeat containing 6B
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53I11 tumor protein p53 inducible protein 11
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAM2 translocation associated membrane protein 2
TRIM44 tripartite motif containing 44
TRIM52 tripartite motif containing 52
TRIM56 tripartite motif containing 56
TSC22D3 TSC22 domain family, member 3
TSPAN5 tetraspanin 5
TTC39B tetratricopeptide repeat domain 39B
TTC7A tetratricopeptide repeat domain 7A
TTLL11 tubulin tyrosine ligase-like family member 11
TUSC1 tumor suppressor candidate 1
UBE2C ubiquitin-conjugating enzyme E2C
UBE2H ubiquitin-conjugating enzyme E2H
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UHMK1 U2AF homology motif (UHM) kinase 1
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
UIMC1 ubiquitin interaction motif containing 1
USP28 ubiquitin specific peptidase 28
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VSIG1 V-set and immunoglobulin domain containing 1
WDR36 WD repeat domain 36
WLS wntless Wnt ligand secretion mediator
XPR1 xenotropic and polytropic retrovirus receptor 1
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
ZBTB10 zinc finger and BTB domain containing 10
ZBTB2 zinc finger and BTB domain containing 2
ZC3HC1 zinc finger, C3HC-type containing 1
ZCCHC11 zinc finger, CCHC domain containing 11
ZDHHC16 zinc finger, DHHC-type containing 16
ZFHX4 zinc finger homeobox 4
ZNF114 zinc finger protein 114
ZNF134 zinc finger protein 134
ZNF160 zinc finger protein 160
ZNF175 zinc finger protein 175
ZNF184 zinc finger protein 184
ZNF197 zinc finger protein 197
ZNF252P zinc finger protein 252, pseudogene
ZNF281 zinc finger protein 281
ZNF285 zinc finger protein 285
ZNF304 zinc finger protein 304
ZNF33B zinc finger protein 33B
ZNF350 zinc finger protein 350
ZNF391 zinc finger protein 391
ZNF445 zinc finger protein 445
ZNF468 zinc finger protein 468
ZNF484 zinc finger protein 484
ZNF488 zinc finger protein 488
ZNF510 zinc finger protein 510
ZNF525 zinc finger protein 525
ZNF530 zinc finger protein 530
ZNF569 zinc finger protein 569
ZNF608 zinc finger protein 608
ZNF613 zinc finger protein 613
ZNF615 zinc finger protein 615
ZNF616 zinc finger protein 616
ZNF702P zinc finger protein 702, pseudogene
ZNF749 zinc finger protein 749
ZNF761 zinc finger protein 761
ZNF836 zinc finger protein 836
ZNHIT3 zinc finger, HIT-type containing 3

low expression

Symbol Name
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
LOC90784 uncharacterized LOC90784
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PNPO pyridoxamine 5'-phosphate oxidase
TOM1L1 target of myb1 (chicken)-like 1
UBXN2B UBX domain protein 2B