Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4742-01A-02R-1514-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

366 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4742-01A-02R-1514-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
ACOT11 acyl-CoA thioesterase 11
ACRV1 acrosomal vesicle protein 1
ACVR1B activin A receptor, type IB
ADAM17 ADAM metallopeptidase domain 17
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
AHCYL1 adenosylhomocysteinase-like 1
AJAP1 adherens junctions associated protein 1
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALKBH3 alkB, alkylation repair homolog 3 (E. coli)
AMBRA1 autophagy/beclin-1 regulator 1
AMOTL1 angiomotin like 1
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANO1 anoctamin 1, calcium activated chloride channel
ANO10 anoctamin 10
ANXA5 annexin A5
AP1B1 adaptor-related protein complex 1, beta 1 subunit
APCDD1L adenomatosis polyposis coli down-regulated 1-like
API5 apoptosis inhibitor 5
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2
ARHGAP1 Rho GTPase activating protein 1
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARRB1 arrestin, beta 1
ATG13 autophagy related 13
ATG2A autophagy related 2A
ATL3 atlastin GTPase 3
ATMIN ATM interactor
ATP9A ATPase, class II, type 9A
BICC1 BicC family RNA binding protein 1
BMP2K BMP2 inducible kinase
BPIFC BPI fold containing family C
BTBD3 BTB (POZ) domain containing 3
C10ORF55 chromosome 10 open reading frame 55
C14ORF1 chromosome 14 open reading frame 1
C3ORF20 chromosome 3 open reading frame 20
C6ORF25 chromosome 6 open reading frame 25
C6ORF89 chromosome 6 open reading frame 89
C7ORF33 chromosome 7 open reading frame 33
C9ORF131 chromosome 9 open reading frame 131
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CARD18 caspase recruitment domain family, member 18
CCL11 chemokine (C-C motif) ligand 11
CD82 CD82 molecule
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDK8 cyclin-dependent kinase 8
CDSN corneodesmosin
CES5A carboxylesterase 5A
CHMP2B charged multivesicular body protein 2B
CHPF2 chondroitin polymerizing factor 2
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CKAP2L cytoskeleton associated protein 2-like
CLMP CXADR-like membrane protein
CLSTN2 calsyntenin 2
COL12A1 collagen, type XII, alpha 1
COL5A3 collagen, type V, alpha 3
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSAG1 chondrosarcoma associated gene 1
CSAG2 CSAG family, member 2
CSAG3 CSAG family, member 3
CSMD2 CUB and Sushi multiple domains 2
CTNNBIP1 catenin, beta interacting protein 1
CTSA cathepsin A
CTTN cortactin
CXORF38 chromosome X open reading frame 38
CXORF66 chromosome X open reading frame 66
CYB561D1 cytochrome b561 family, member D1
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae)
DENND2C DENN/MADD domain containing 2C
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
DHDDS dehydrodolichyl diphosphate synthase
DNAJB8 DnaJ (Hsp40) homolog, subfamily B, member 8
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5
DNASE1L1 deoxyribonuclease I-like 1
DOCK9 dedicator of cytokinesis 9
DOK4 docking protein 4
DUSP18 dual specificity phosphatase 18
EHD1 EH-domain containing 1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EIF5 eukaryotic translation initiation factor 5
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ELMOD1 ELMO/CED-12 domain containing 1
ELOVL1 ELOVL fatty acid elongase 1
ELOVL4 ELOVL fatty acid elongase 4
EML3 echinoderm microtubule associated protein like 3
ENDOD1 endonuclease domain containing 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPAS1 endothelial PAS domain protein 1
EPS15 epidermal growth factor receptor pathway substrate 15
EREG epiregulin
ESYT3 extended synaptotagmin-like protein 3
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EVI5 ecotropic viral integration site 5
EXT2 exostosin glycosyltransferase 2
FADD Fas (TNFRSF6)-associated via death domain
FAM122C family with sequence similarity 122C
FAM196B family with sequence similarity 196, member B
FAM49A family with sequence similarity 49, member A
FAP fibroblast activation protein, alpha
FBXO45 F-box protein 45
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FGF16 fibroblast growth factor 16
FKSG29 FKSG29
FLNA filamin A, alpha
FRMD6 FERM domain containing 6
FRMD8 FERM domain containing 8
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3
GJA3 gap junction protein, alpha 3, 46kDa
GJB2 gap junction protein, beta 2, 26kDa
GJC1 gap junction protein, gamma 1, 45kDa
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GPR39 G protein-coupled receptor 39
GSDMA gasdermin A
GTSF1 gametocyte specific factor 1
HEG1 heart development protein with EGF-like domains 1
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HIAT1 hippocampus abundant transcript 1
HIPK3 homeodomain interacting protein kinase 3
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMGXB4 HMG box domain containing 4
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HPSE heparanase
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12
HYAL4 hyaluronoglucosaminidase 4
IDI1 isopentenyl-diphosphate delta isomerase 1
IFNLR1 interferon, lambda receptor 1
IL17RA interleukin 17 receptor A
IL22RA1 interleukin 22 receptor, alpha 1
IPO5 importin 5
IQSEC2 IQ motif and Sec7 domain 2
JAG1 jagged 1
JAK1 Janus kinase 1
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KDM5C lysine (K)-specific demethylase 5C
KIF26B kinesin family member 26B
KIRREL kin of IRRE like (Drosophila)
KLK6 kallikrein-related peptidase 6
KLK9 kallikrein-related peptidase 9
KPNA3 karyopherin alpha 3 (importin alpha 4)
LCE1A late cornified envelope 1A
LCE1C late cornified envelope 1C
LCE1D late cornified envelope 1D
LCE2B late cornified envelope 2B
LCE4A late cornified envelope 4A
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LHX1 LIM homeobox 1
LIMK2 LIM domain kinase 2
LIMS1 LIM and senescent cell antigen-like domains 1
LIPK lipase, family member K
LIPN lipase, family member N
LOC100126784 uncharacterized LOC100126784
LOC221122 uncharacterized LOC221122
LOC284441 actin-related protein 2 pseudogene
LPPR4 lipid phosphate phosphatase-related protein type 4
LPXN leupaxin
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRC41 leucine rich repeat containing 41
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LUZP1 leucine zipper protein 1
LYPD5 LY6/PLAUR domain containing 5
MAGEA10 melanoma antigen family A10
MAGEA12 melanoma antigen family A12
MAGEA2 melanoma antigen family A2
MAGEA3 melanoma antigen family A3
MAGEA4 melanoma antigen family A4
MAGEA6 melanoma antigen family A6
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MEFV Mediterranean fever
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MICALCL MICAL C-terminal like
MID2 midline 2
MIEF1 mitochondrial elongation factor 1
MKKS McKusick-Kaufman syndrome
MMP25 matrix metallopeptidase 25
MMP9 matrix metallopeptidase 9
MOB1A MOB kinase activator 1A
MPZL3 myelin protein zero-like 3
MRGPRX2 MAS-related GPR, member X2
MRPL49 mitochondrial ribosomal protein L49
MSMO1 methylsterol monooxygenase 1
MTCH2 mitochondrial carrier 2
MTMR2 myotubularin related protein 2
MTMR6 myotubularin related protein 6
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYO1B myosin IB
MYO1D myosin ID
NCK2 NCK adaptor protein 2
NCOA3 nuclear receptor coactivator 3
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1
NEU2 sialidase 2 (cytosolic sialidase)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NIPAL1 NIPA-like domain containing 1
NLRP10 NLR family, pyrin domain containing 10
NOL4L nucleolar protein 4-like
NOTCH2 notch 2
NPC1L1 NPC1-like 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OAF OAF homolog (Drosophila)
OPTC opticin
OR10A6 olfactory receptor, family 10, subfamily A, member 6 (gene/pseudogene)
OR4A47 olfactory receptor, family 4, subfamily A, member 47
OR7E24 olfactory receptor, family 7, subfamily E, member 24
OSBP oxysterol binding protein
OSBPL2 oxysterol binding protein-like 2
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PANX1 pannexin 1
PARVA parvin, alpha
PCNXL3 pecanex-like 3 (Drosophila)
PCSK9 proprotein convertase subtilisin/kexin type 9
PGM3 phosphoglucomutase 3
PI3 peptidase inhibitor 3, skin-derived
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLA2G4E phospholipase A2, group IVE
PLBD2 phospholipase B domain containing 2
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
POF1B premature ovarian failure, 1B
POFUT1 protein O-fucosyltransferase 1
PPIF peptidylprolyl isomerase F
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PQLC2 PQ loop repeat containing 2
PQLC3 PQ loop repeat containing 3
PRDM11 PR domain containing 11
PRKCE protein kinase C, epsilon
PRKD3 protein kinase D3
PTAFR platelet-activating factor receptor
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPRG protein tyrosine phosphatase, receptor type, G
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
QPCT glutaminyl-peptide cyclotransferase
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB22A RAB22A, member RAS oncogene family
RAB27B RAB27B, member RAS oncogene family
RAB30 RAB30, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
RASA3 RAS p21 protein activator 3
RBM12 RNA binding motif protein 12
RCAN3 RCAN family member 3
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RIC8A RIC8 guanine nucleotide exchange factor A
RNASEH1 ribonuclease H1
RNF121 ring finger protein 121
RNF26 ring finger protein 26
ROR2 receptor tyrosine kinase-like orphan receptor 2
RP1L1 retinitis pigmentosa 1-like 1
RPN2 ribophorin II
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RRAGC Ras-related GTP binding C
RSC1A1 regulatory solute carrier protein, family 1, member 1
S100A7A S100 calcium binding protein A7A
SC5D sterol-C5-desaturase
SCAMP4 secretory carrier membrane protein 4
SCARB2 scavenger receptor class B, member 2
SDC3 syndecan 3
SEC23B Sec23 homolog B (S. cerevisiae)
SEC24B SEC24 family member B
SEC31A SEC31 homolog A (S. cerevisiae)
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SERINC3 serine incorporator 3
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SGMS2 sphingomyelin synthase 2
SH3RF3 SH3 domain containing ring finger 3
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC35E4 solute carrier family 35, member E4
SLC35F2 solute carrier family 35, member F2
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLX4IP SLX4 interacting protein
SMC1A structural maintenance of chromosomes 1A
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNIP1 Smad nuclear interacting protein 1
SNX12 sorting nexin 12
SPIN4 spindlin family, member 4
SPRED2 sprouty-related, EVH1 domain containing 2
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SPTY2D1 SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
SQLE squalene epoxidase
SREBF2 sterol regulatory element binding transcription factor 2
STARD4 StAR-related lipid transfer (START) domain containing 4
STK24 serine/threonine kinase 24
STRN striatin, calmodulin binding protein
SUPT20HL2 suppressor of Ty 20 homolog (S. cerevisiae)-like 2
SYS1-DBNDD2 SYS1-DBNDD2 readthrough (NMD candidate)
SYT7 synaptotagmin VII
SZRD1 SUZ RNA binding domain containing 1
SZT2 seizure threshold 2 homolog (mouse)
TASP1 taspase, threonine aspartase, 1
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
TDO2 tryptophan 2,3-dioxygenase
TGFA transforming growth factor, alpha
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TM9SF2 transmembrane 9 superfamily member 2
TM9SF4 transmembrane 9 superfamily protein member 4
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMEM127 transmembrane protein 127
TMEM50A transmembrane protein 50A
TMEM86A transmembrane protein 86A
TMEM87B transmembrane protein 87B
TMPRSS13 transmembrane protease, serine 13
TMX4 thioredoxin-related transmembrane protein 4
TNIP3 TNFAIP3 interacting protein 3
TP53I11 tumor protein p53 inducible protein 11
TRAF3 TNF receptor-associated factor 3
TREX2 three prime repair exonuclease 2
TRIM62 tripartite motif containing 62
TSHB thyroid stimulating hormone, beta
TSPAN5 tetraspanin 5
TXNDC2 thioredoxin domain containing 2 (spermatozoa)
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE4A ubiquitination factor E4A
UBTD1 ubiquitin domain containing 1
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
UNC13D unc-13 homolog D (C. elegans)
UNC93A unc-93 homolog A (C. elegans)
USP47 ubiquitin specific peptidase 47
VANGL1 VANGL planar cell polarity protein 1
VGLL3 vestigial-like family member 3
VRTN vertebrae development associated
VWC2L von Willebrand factor C domain containing protein 2-like
WBP1L WW domain binding protein 1-like
WDFY3 WD repeat and FYVE domain containing 3
WFDC12 WAP four-disulfide core domain 12
WFDC5 WAP four-disulfide core domain 5
WISP1 WNT1 inducible signaling pathway protein 1
XG Xg blood group
XKRX XK, Kell blood group complex subunit-related, X-linked
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZC3H12C zinc finger CCCH-type containing 12C
ZDHHC20 zinc finger, DHHC-type containing 20
ZDHHC5 zinc finger, DHHC-type containing 5
ZFP91 ZFP91 zinc finger protein
ZHX3 zinc fingers and homeoboxes 3
ZNF107 zinc finger protein 107
ZNF35 zinc finger protein 35
ZNF469 zinc finger protein 469
ZNF679 zinc finger protein 679
ZNF697 zinc finger protein 697

low expression

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
ANAPC7 anaphase promoting complex subunit 7
BANP BTG3 associated nuclear protein
C2ORF42 chromosome 2 open reading frame 42
NSRP1 nuclear speckle splicing regulatory protein 1
PTPN3 protein tyrosine phosphatase, non-receptor type 3
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1