Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4734-01A-01R-1436-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

374 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4734-01A-01R-1436-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ACER2 alkaline ceramidase 2
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACSL5 acyl-CoA synthetase long-chain family member 5
ACTN1 actinin, alpha 1
ACTR10 actin-related protein 10 homolog (S. cerevisiae)
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ADAM21 ADAM metallopeptidase domain 21
ADAM21P1 ADAM metallopeptidase domain 21 pseudogene 1
ADCY4 adenylate cyclase 4
ADGRE1 adhesion G protein-coupled receptor E1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6
AHNAK2 AHNAK nucleoprotein 2
ALDH1L2 aldehyde dehydrogenase 1 family, member L2
ALG9 ALG9, alpha-1,2-mannosyltransferase
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANXA2 annexin A2
ANXA2P2 annexin A2 pseudogene 2
ANXA3 annexin A3
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APAF1 apoptotic peptidase activating factor 1
APEH acylaminoacyl-peptide hydrolase
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1
ARF3 ADP-ribosylation factor 3
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
ATP10D ATPase, class V, type 10D
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
ATXN7L3B ataxin 7-like 3B
AVPR1A arginine vasopressin receptor 1A
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCO1 beta-carotene oxygenase 1
BMP2K BMP2 inducible kinase
C12ORF49 chromosome 12 open reading frame 49
C1ORF74 chromosome 1 open reading frame 74
C9ORF41 chromosome 9 open reading frame 41
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCDC109B coiled-coil domain containing 109B
CCND2 cyclin D2
CCNYL1 cyclin Y-like 1
CD300E CD300e molecule
CDCP1 CUB domain containing protein 1
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CEACAM19 carcinoembryonic antigen-related cell adhesion molecule 19
CFB complement factor B
CFI complement factor I
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLCA2 chloride channel accessory 2
CLCF1 cardiotrophin-like cytokine factor 1
CLEC6A C-type lectin domain family 6, member A
CLNK cytokine-dependent hematopoietic cell linker
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
CNGB1 cyclic nucleotide gated channel beta 1
CNN2 calponin 2
CNTN1 contactin 1
COPZ1 coatomer protein complex, subunit zeta 1
CORO1C coronin, actin binding protein, 1C
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CPXCR1 CPX chromosome region, candidate 1
CRYGS crystallin, gamma S
CSMD3 CUB and Sushi multiple domains 3
CTNND1 catenin (cadherin-associated protein), delta 1
CTSL3P cathepsin L family member 3, pseudogene
CYCSP52 cytochrome c, somatic pseudogene 52
DCAF5 DDB1 and CUL4 associated factor 5
DCP1A decapping mRNA 1A
DCTN2 dynactin 2 (p50)
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
DEFB103B defensin, beta 103B
DEFB104A defensin, beta 104A
DEFB106A defensin, beta 106A
DEFB107A defensin, beta 107A
DENND1B DENN/MADD domain containing 1B
DENR density-regulated protein
DGKA diacylglycerol kinase, alpha 80kDa
DIAPH1 diaphanous-related formin 1
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila)
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNAAF3 dynein, axonemal, assembly factor 3
DNM3 dynamin 3
DSC2 desmocollin 2
DSC3 desmocollin 3
DSE dermatan sulfate epimerase
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EAF1 ELL associated factor 1
EGR4 early growth response 4
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF4A3 eukaryotic translation initiation factor 4A3
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ELMSAN1 ELM2 and Myb/SANT-like domain containing 1
ELP3 elongator acetyltransferase complex subunit 3
EML5 echinoderm microtubule associated protein like 5
ENO1 enolase 1, (alpha)
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EP400 E1A binding protein p400
ERC1 ELKS/RAB6-interacting/CAST family member 1
EREG epiregulin
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ERI1 exoribonuclease 1
ERP27 endoplasmic reticulum protein 27
ESYT1 extended synaptotagmin-like protein 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
ETV3 ets variant 3
ETV3L ets variant 3-like
EXD2 exonuclease 3'-5' domain containing 2
EXOC5 exocyst complex component 5
EXOC6B exocyst complex component 6B
EXTL3 exostosin-like glycosyltransferase 3
FAM205A family with sequence similarity 205, member A
FAM63B family with sequence similarity 63, member B
FAM98A family with sequence similarity 98, member A
FER fer (fps/fes related) tyrosine kinase
FER1L6 fer-1-like family member 6
FERMT1 fermitin family member 1
FGL1 fibrinogen-like 1
FLNB filamin B, beta
FMN1 formin 1
FNTB farnesyltransferase, CAAX box, beta
FOS FBJ murine osteosarcoma viral oncogene homolog
FURIN furin (paired basic amino acid cleaving enzyme)
FZD5 frizzled class receptor 5
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GALT galactose-1-phosphate uridylyltransferase
GANC glucosidase, alpha; neutral C
GBP1 guanylate binding protein 1, interferon-inducible
GBP7 guanylate binding protein 7
GCH1 GTP cyclohydrolase 1
GFOD1 glucose-fructose oxidoreductase domain containing 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLIPR1 GLI pathogenesis-related 1
GMFB glia maturation factor, beta
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GOLGA3 golgin A3
GPHN gephyrin
GPR157 G protein-coupled receptor 157
GPR31 G protein-coupled receptor 31
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GPR52 G protein-coupled receptor 52
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HCFC2 host cell factor C2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HSPA4L heat shock 70kDa protein 4-like
HSPA8 heat shock 70kDa protein 8
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IGFL1 IGF-like family member 1
IL12RB1 interleukin 12 receptor, beta 1
IL1RL1 interleukin 1 receptor-like 1
ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCTD10 potassium channel tetramerization domain containing 10
KCTD14 potassium channel tetramerization domain containing 14
KCTD9 potassium channel tetramerization domain containing 9
KHNYN KH and NYN domain containing
KIAA0020 KIAA0020
KIAA0586 KIAA0586
KIAA0922 KIAA0922
KIAA1033 KIAA1033
KIAA1161 KIAA1161
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KLC1 kinesin light chain 1
KLHL9 kelch-like family member 9
KRT14 keratin 14, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRT6C keratin 6C, type II
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LDHA lactate dehydrogenase A
LIMA1 LIM domain and actin binding 1
LMBR1L limb development membrane protein 1-like
LOC154761 family with sequence similarity 115, member C pseudogene
LOC284441 actin-related protein 2 pseudogene
LOC641367 cyclin Y-like 1 pseudogene
LTB4R leukotriene B4 receptor
LTB4R2 leukotriene B4 receptor 2
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MAST4 microtubule associated serine/threonine kinase family member 4
METAP2 methionyl aminopeptidase 2
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MLEC malectin
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MR1 major histocompatibility complex, class I-related
MSN moesin
MTF1 metal-regulatory transcription factor 1
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTMR11 myotubularin related protein 11
MTMR9 myotubularin related protein 9
MYO1G myosin IG
NAV3 neuron navigator 3
NCKAP5 NCK-associated protein 5
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NEK9 NIMA-related kinase 9
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NHLRC2 NHL repeat containing 2
NIPAL1 NIPA-like domain containing 1
NIPAL4 NIPA-like domain containing 4
NOL6 nucleolar protein 6 (RNA-associated)
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NUMB numb homolog (Drosophila)
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OR2D2 olfactory receptor, family 2, subfamily D, member 2
OR2L1P olfactory receptor, family 2, subfamily L, member 1 pseudogene
OR51E2 olfactory receptor, family 51, subfamily E, member 2
OR52I1 olfactory receptor, family 52, subfamily I, member 1
OR52K2 olfactory receptor, family 52, subfamily K, member 2
OR7E91P olfactory receptor, family 7, subfamily E, member 91 pseudogene
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2
OSR2 odd-skipped related transciption factor 2
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PANX1 pannexin 1
PCBP2 poly(rC) binding protein 2
PCDHGB2 protocadherin gamma subfamily B, 2
PCDHGC5 protocadherin gamma subfamily C, 5
PCNX pecanex homolog (Drosophila)
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDCD6IP programmed cell death 6 interacting protein
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PGAM4 phosphoglycerate mutase family member 4
PGK1 phosphoglycerate kinase 1
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PKM pyruvate kinase, muscle
PLCD1 phospholipase C, delta 1
PLCZ1 phospholipase C, zeta 1
PLEK2 pleckstrin 2
PML promyelocytic leukemia
PNP purine nucleoside phosphorylase
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POU2F3 POU class 2 homeobox 3
PP2D1 protein phosphatase 2C-like domain containing 1
PPIAL4E peptidylprolyl isomerase A (cyclophilin A)-like 4E
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PPP4R2 protein phosphatase 4, regulatory subunit 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRDM4 PR domain containing 4
PRO0628 uncharacterized LOC29053
PROX2 prospero homeobox 2
PRPF40B PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
PSEN1 presenilin 1
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PTPRD protein tyrosine phosphatase, receptor type, D
PWP1 PWP1 homolog (S. cerevisiae)
PYGL phosphorylase, glycogen, liver
RAB35 RAB35, member RAS oncogene family
RAB38 RAB38, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RACGAP1 Rac GTPase activating protein 1
RACGAP1P Rac GTPase activating protein 1 pseudogene
RAET1L retinoic acid early transcript 1L
RAN RAN, member RAS oncogene family
RASSF3 Ras association (RalGDS/AF-6) domain family member 3
RBM45 RNA binding motif protein 45
RBMS2 RNA binding motif, single stranded interacting protein 2
RIMS3 regulating synaptic membrane exocytosis 3
RNASE10 ribonuclease, RNase A family, 10 (non-active)
RNF213 ring finger protein 213
RRAGA Ras-related GTP binding A
RTN1 reticulon 1
RXFP3 relaxin/insulin-like family peptide receptor 3
SAMHD1 SAM domain and HD domain 1
SBNO1 strawberry notch homolog 1 (Drosophila)
SCAPER S-phase cyclin A-associated protein in the ER
SCNN1D sodium channel, non voltage gated 1 delta subunit
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SGK223 homolog of rat pragma of Rnd2
SH2D5 SH2 domain containing 5
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3
SHISA5 shisa family member 5
SIGMAR1 sigma non-opioid intracellular receptor 1
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A51 solute carrier family 25, member 51
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC35F6 solute carrier family 35, member F6
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC39A9 solute carrier family 39, member 9
SLFN12L schlafen family member 12-like
SLFN5 schlafen family member 5
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SNORA45B small nucleolar RNA, H/ACA box 45B
SNORA47 small nucleolar RNA, H/ACA box 47
SNX29 sorting nexin 29
SOX6 SRY (sex determining region Y)-box 6
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPRED3 sprouty-related, EVH1 domain containing 3
SPRYD3 SPRY domain containing 3
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
SUSD6 sushi domain containing 6
SYNJ2BP synaptojanin 2 binding protein
TAS2R3 taste receptor, type 2, member 3
TCAF2 TRPM8 channel-associated factor 2
TDG thymine-DNA glycosylase
TGM1 transglutaminase 1
TLDC1 TBC/LysM-associated domain containing 1
TLR3 toll-like receptor 3
TM7SF3 transmembrane 7 superfamily member 3
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMCC3 transmembrane and coiled-coil domain family 3
TMED2 transmembrane emp24 domain trafficking protein 2
TMEM106A transmembrane protein 106A
TMEM110 transmembrane protein 110
TMEM229B transmembrane protein 229B
TMEM30B transmembrane protein 30B
TMEM52B transmembrane protein 52B
TMPPE transmembrane protein with metallophosphoesterase domain
TMTC3 transmembrane and tetratricopeptide repeat containing 3
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TOX4 TOX high mobility group box family member 4
TRAFD1 TRAF-type zinc finger domain containing 1
TRIM25 tripartite motif containing 25
TRIM36 tripartite motif containing 36
TRIM40 tripartite motif containing 40
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae)
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TRPS1 trichorhinophalangeal syndrome I
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TSPAN10 tetraspanin 10
TSPYL1 TSPY-like 1
TTC39B tetratricopeptide repeat domain 39B
TUBA1B tubulin, alpha 1b
TUBA1C tubulin, alpha 1c
TUBB3 tubulin, beta 3 class III
TWF1 twinfilin actin binding protein 1
UBAP1 ubiquitin associated protein 1
UBAP2 ubiquitin associated protein 2
UBE3B ubiquitin protein ligase E3B
UHRF1BP1L UHRF1 binding protein 1-like
USP15 ubiquitin specific peptidase 15
VCP valosin containing protein
WARS tryptophanyl-tRNA synthetase
WDR1 WD repeat domain 1
WDR37 WD repeat domain 37
WSB2 WD repeat and SOCS box containing 2
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
YLPM1 YLP motif containing 1
ZAN zonadhesin (gene/pseudogene)
ZBTB37 zinc finger and BTB domain containing 37
ZBTB5 zinc finger and BTB domain containing 5
ZC3H12C zinc finger CCCH-type containing 12C
ZC4H2 zinc finger, C4H2 domain containing
ZFYVE26 zinc finger, FYVE domain containing 26
ZNF618 zinc finger protein 618
ZNF699 zinc finger protein 699
ZNF710 zinc finger protein 710

low expression

Symbol Name
SCRIB scribbled planar cell polarity protein
SMYD5 SMYD family member 5
THAP11 THAP domain containing 11
TMUB2 transmembrane and ubiquitin-like domain containing 2
TYW3 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)