Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4729-01A-01R-1436-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

425 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4729-01A-01R-1436-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AACS acetoacetyl-CoA synthetase
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACACA acetyl-CoA carboxylase alpha
ACTL7A actin-like 7A
ADAM10 ADAM metallopeptidase domain 10
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ADGRA3 adhesion G protein-coupled receptor A3
ADIPOR1 adiponectin receptor 1
ADIPOR2 adiponectin receptor 2
AFAP1L1 actin filament associated protein 1-like 1
AGO2 argonaute RISC catalytic component 2
AGO3 argonaute RISC catalytic component 3
AGPAT4-IT1 AGPAT4 intronic transcript 1
ALG11 ALG11, alpha-1,2-mannosyltransferase
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase
ALOXE3 arachidonate lipoxygenase 3
ANO2 anoctamin 2, calcium activated chloride channel
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
AQR aquarius intron-binding spliceosomal factor
ARF3 ADP-ribosylation factor 3
ARGFXP2 arginine-fifty homeobox pseudogene 2
ARHGAP32 Rho GTPase activating protein 32
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ARRDC4 arrestin domain containing 4
ASB7 ankyrin repeat and SOCS box containing 7
ATE1 arginyltransferase 1
ATOH1 atonal homolog 1 (Drosophila)
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATXN7L3 ataxin 7-like 3
AVPR1A arginine vasopressin receptor 1A
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2
B4GALNT3 beta-1,4-N-acetyl-galactosaminyl transferase 3
BCAM basal cell adhesion molecule (Lutheran blood group)
BECN1 beclin 1, autophagy related
BRI3BP BRI3 binding protein
BROX BRO1 domain and CAAX motif containing
BRS3 bombesin-like receptor 3
BTBD19 BTB (POZ) domain containing 19
BTNL2 butyrophilin-like 2
BUD13 BUD13 homolog (S. cerevisiae)
C10ORF67 chromosome 10 open reading frame 67
C11ORF45 chromosome 11 open reading frame 45
C12ORF4 chromosome 12 open reading frame 4
C12ORF49 chromosome 12 open reading frame 49
C15ORF39 chromosome 15 open reading frame 39
C6ORF106 chromosome 6 open reading frame 106
C7ORF61 chromosome 7 open reading frame 61
C9ORF106 chromosome 9 open reading frame 106
CADM4 cell adhesion molecule 4
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CANX calnexin
CARD17 caspase recruitment domain family, member 17
CARD18 caspase recruitment domain family, member 18
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CASP4 caspase 4, apoptosis-related cysteine peptidase
CATSPER4 cation channel, sperm associated 4
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCDC38 coiled-coil domain containing 38
CCDC87 coiled-coil domain containing 87
CCNT1 cyclin T1
CDRT15 CMT1A duplicated region transcript 15
CDRT15P1 CMT1A duplicated region transcript 15 pseudogene 1
CEACAM22P carcinoembryonic antigen-related cell adhesion molecule 22, pseudogene
CERK ceramide kinase
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CLEC12A C-type lectin domain family 12, member A
CLPTM1L CLPTM1-like
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CNTF ciliary neurotrophic factor
COBLL1 cordon-bleu WH2 repeat protein-like 1
COG3 component of oligomeric golgi complex 3
CORO2B coronin, actin binding protein, 2B
CPA3 carboxypeptidase A3 (mast cell)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CUL5 cullin 5
CYFIP1 cytoplasmic FMR1 interacting protein 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
DAD1P1 defender against cell death 1 pseudogene 1
DCN decorin
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX55 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
DGKH diacylglycerol kinase, eta
DHCR24 24-dehydrocholesterol reductase
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37
DISP2 dispatched homolog 2 (Drosophila)
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DOCK9 dedicator of cytokinesis 9
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
DPH3P1 diphthamide biosynthesis 3 pseudogene 1
DPP8 dipeptidyl-peptidase 8
DPY19L3 dpy-19-like 3 (C. elegans)
DUOX1 dual oxidase 1
DUSP9 dual specificity phosphatase 9
EDC3 enhancer of mRNA decapping 3
EEF1DP3 eukaryotic translation elongation factor 1 delta pseudogene 3
EHD4 EH-domain containing 4
EI24 etoposide induced 2.4
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EIF4H eukaryotic translation initiation factor 4H
ELF4 E74-like factor 4 (ets domain transcription factor)
EPPK1 epiplakin 1
ERC1 ELKS/RAB6-interacting/CAST family member 1
EXOC3 exocyst complex component 3
FADS6 fatty acid desaturase 6
FAM98B family with sequence similarity 98, member B
FBXL18 F-box and leucine-rich repeat protein 18
FDPSP2 farnesyl diphosphate synthase pseudogene 2
FEM1B fem-1 homolog b (C. elegans)
FOXM1 forkhead box M1
FOXRED1 FAD-dependent oxidoreductase domain containing 1
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GAST gastrin
GATSL2 GATS protein-like 2
GCGR glucagon receptor
GCSAML germinal center-associated, signaling and motility-like
GLRA1 glycine receptor, alpha 1
GPALPP1 GPALPP motifs containing 1
GPR176 G protein-coupled receptor 176
GPR75 G protein-coupled receptor 75
GRIK1 glutamate receptor, ionotropic, kainate 1
GRM4 glutamate receptor, metabotropic 4
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HACD2 3-hydroxyacyl-CoA dehydratase 2
HBZ hemoglobin, zeta
HDC histidine decarboxylase
HEATR1 HEAT repeat containing 1
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIPK3 homeodomain interacting protein kinase 3
HIST1H1A histone cluster 1, H1a
HIST1H2AH histone cluster 1, H2ah
HIST1H2BB histone cluster 1, H2bb
HIST1H3J histone cluster 1, H3j
HIST1H4C histone cluster 1, H4c
HIST1H4D histone cluster 1, H4d
HIST1H4F histone cluster 1, H4f
HIST1H4K histone cluster 1, H4k
HRH1 histamine receptor H1
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HYOU1 hypoxia up-regulated 1
ICE1 interactor of little elongation complex ELL subunit 1
IDE insulin-degrading enzyme
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
IFFO2 intermediate filament family orphan 2
IFNA5 interferon, alpha 5
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IFNLR1 interferon, lambda receptor 1
IGF1R insulin-like growth factor 1 receptor
IL10RB interleukin 10 receptor, beta
IL31RA interleukin 31 receptor A
IL6R interleukin 6 receptor
INO80 INO80 complex subunit
IPO5 importin 5
ITM2B integral membrane protein 2B
ITSN1 intersectin 1 (SH3 domain protein)
KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2
KDM5A lysine (K)-specific demethylase 5A
KDSR 3-ketodihydrosphingosine reductase
KIAA0100 KIAA0100
KIF7 kinesin family member 7
KLF13 Kruppel-like factor 13
KLK13 kallikrein-related peptidase 13
KPNA3 karyopherin alpha 3 (importin alpha 4)
KRT80 keratin 80, type II
LCMT2 leucine carboxyl methyltransferase 2
LDHAL6B lactate dehydrogenase A-like 6B
LGALS8 lectin, galactoside-binding, soluble, 8
LHX4 LIM homeobox 4
LINC00161 long intergenic non-protein coding RNA 161
LINC00174 long intergenic non-protein coding RNA 174
LINC01559 long intergenic non-protein coding RNA 1559
LINC01599 long intergenic non-protein coding RNA 1599
LIPN lipase, family member N
LOC100130264 uncharacterized LOC100130264
LOC286238 uncharacterized LOC286238
LOC400927 TPTE and PTEN homologous inositol lipid phosphatase pseudogene
LOC728024 chromosome X open reading frame 56 pseudogene
LOC90246 uncharacterized LOC90246
LOC90834
LPCAT1 lysophosphatidylcholine acyltransferase 1
LPPR4 lipid phosphate phosphatase-related protein type 4
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LTN1 listerin E3 ubiquitin protein ligase 1
LUZP1 leucine zipper protein 1
LYST lysosomal trafficking regulator
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK6 mitogen-activated protein kinase 6
MAPKBP1 mitogen-activated protein kinase binding protein 1
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MBNL2 muscleblind-like splicing regulator 2
MCTP1 multiple C2 domains, transmembrane 1
MCTP2 multiple C2 domains, transmembrane 2
MKL2 MKL/myocardin-like 2
MLXIP MLX interacting protein
MPZL3 myelin protein zero-like 3
MRPL13 mitochondrial ribosomal protein L13
MRPS6 mitochondrial ribosomal protein S6
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MTUS2 microtubule associated tumor suppressor candidate 2
MTVR2 mouse mammary tumor virus receptor homolog 2
MYADM myeloid-associated differentiation marker
MYO1C myosin IC
MYO1E myosin IE
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NCOR2 nuclear receptor corepressor 2
NDC1 NDC1 transmembrane nucleoporin
NDFIP2 Nedd4 family interacting protein 2
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
NEU2 sialidase 2 (cytosolic sialidase)
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NID1 nidogen 1
NIPAL2 NIPA-like domain containing 2
NOL9 nucleolar protein 9
NPY4R neuropeptide Y receptor Y4
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
OLFM1 olfactomedin 1
OR10A2 olfactory receptor, family 10, subfamily A, member 2
OR10H5 olfactory receptor, family 10, subfamily H, member 5
OR1F1 olfactory receptor, family 1, subfamily F, member 1
OR2AE1 olfactory receptor, family 2, subfamily AE, member 1
OR2L2 olfactory receptor, family 2, subfamily L, member 2
OR2T11 olfactory receptor, family 2, subfamily T, member 11 (gene/pseudogene)
OR52W1 olfactory receptor, family 52, subfamily W, member 1
OR56A1 olfactory receptor, family 56, subfamily A, member 1
OR6C2 olfactory receptor, family 6, subfamily C, member 2
OSMR oncostatin M receptor
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAPD7 PAP associated domain containing 7
PAQR5 progestin and adipoQ receptor family member V
PCDHGB7 protocadherin gamma subfamily B, 7
PCSK6 proprotein convertase subtilisin/kexin type 6
PDC phosducin
PDCD6 programmed cell death 6
PDIA3 protein disulfide isomerase family A, member 3
PDIA3P1 protein disulfide isomerase family A, member 3 pseudogene 1
PDIA6 protein disulfide isomerase family A, member 6
PDZD8 PDZ domain containing 8
PIGS phosphatidylinositol glycan anchor biosynthesis, class S
PITPNA phosphatidylinositol transfer protein, alpha
PLA2G4E phospholipase A2, group IVE
PLBD1 phospholipase B domain containing 1
PLCD3 phospholipase C, delta 3
PLXDC1 plexin domain containing 1
POM121 POM121 transmembrane nucleoporin
POU4F3 POU class 4 homeobox 3
PP2D1 protein phosphatase 2C-like domain containing 1
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRAP1 proline-rich acidic protein 1
PRKCG protein kinase C, gamma
PRO0611 PRO0611 protein
PROSC proline synthetase co-transcribed homolog (bacterial)
PROSER1 proline and serine rich 1
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PUS3 pseudouridylate synthase 3
RAB4A RAB4A, member RAS oncogene family
RAET1G retinoic acid early transcript 1G
RBM26 RNA binding motif protein 26
RBMS2 RNA binding motif, single stranded interacting protein 2
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RCOR1 REST corepressor 1
REEP1 receptor accessory protein 1
RIMS3 regulating synaptic membrane exocytosis 3
RNASE9 ribonuclease, RNase A family, 9 (non-active)
RNF111 ring finger protein 111
RNF144B ring finger protein 144B
RNPEP arginyl aminopeptidase (aminopeptidase B)
RPE65 retinal pigment epithelium-specific protein 65kDa
RPL23AP64 ribosomal protein L23a pseudogene 64
RPPH1 ribonuclease P RNA component H1
RPUSD4 RNA pseudouridylate synthase domain containing 4
RRH retinal pigment epithelium-derived rhodopsin homolog
RUNDC3A RUN domain containing 3A
SBF1 SET binding factor 1
SBNO1 strawberry notch homolog 1 (Drosophila)
SCAF4 SR-related CTD-associated factor 4
SCAMP2 secretory carrier membrane protein 2
SCARA5 scavenger receptor class A, member 5
SCARB1 scavenger receptor class B, member 1
SCARNA10 small Cajal body-specific RNA 10
SCARNA5 small Cajal body-specific RNA 5
SCN4B sodium channel, voltage gated, type IV beta subunit
SCYL2 SCY1-like 2 (S. cerevisiae)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINA13P serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 13, pseudogene
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
SFPQ splicing factor proline/glutamine-rich
SH3BP5L SH3-binding domain protein 5-like
SH3PXD2A SH3 and PX domains 2A
SIDT2 SID1 transmembrane family, member 2
SIGLEC6 sialic acid binding Ig-like lectin 6
SIK3 SIK family kinase 3
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13
SLC35F2 solute carrier family 35, member F2
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A4 solute carrier family 7, member 4
SLC7A5P2 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 2
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMCR5 Smith-Magenis syndrome chromosome region, candidate 5 (non-protein coding)
SNORA74A small nucleolar RNA, H/ACA box 74A
SNORD17 small nucleolar RNA, C/D box 17
SOCS7 suppressor of cytokine signaling 7
SON SON DNA binding protein
SPACA4 sperm acrosome associated 4
SPDYE6 speedy/RINGO cell cycle regulator family member E6
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SPINK6 serine peptidase inhibitor, Kazal type 6
SPPL2A signal peptide peptidase like 2A
SPRR2C small proline-rich protein 2C (pseudogene)
SPRR2G small proline-rich protein 2G
SRPR signal recognition particle receptor (docking protein)
SST somatostatin
STK24 serine/threonine kinase 24
STRAP serine/threonine kinase receptor associated protein
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
STXBP1 syntaxin binding protein 1
SYCN syncollin
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TARSL2 threonyl-tRNA synthetase-like 2
TAS2R14 taste receptor, type 2, member 14
TAS2R30 taste receptor, type 2, member 30
TBPL2 TATA box binding protein like 2
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCTN2 tectonic family member 2
TEAD4 TEA domain family member 4
TEP1 telomerase-associated protein 1
TFAMP1 transcription factor A, mitochondrial pseudogene 1
TFB2M transcription factor B2, mitochondrial
TIGAR TP53 induced glycolysis regulatory phosphatase
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TJP1 tight junction protein 1
TLN2 talin 2
TM4SF4 transmembrane 4 L six family member 4
TM9SF2 transmembrane 9 superfamily member 2
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMED2 transmembrane emp24 domain trafficking protein 2
TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough
TMEM202 transmembrane protein 202
TMEM217 transmembrane protein 217
TMEM50B transmembrane protein 50B
TMEM63B transmembrane protein 63B
TMEM95 transmembrane protein 95
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNK1 tyrosine kinase, non-receptor, 1
TOR1AIP2 torsin A interacting protein 2
TPP2 tripeptidyl peptidase II
TPPP tubulin polymerization promoting protein
TPSAB1 tryptase alpha/beta 1
TRIM13 tripartite motif containing 13
TRIP12 thyroid hormone receptor interactor 12
TSSK3 testis-specific serine kinase 3
TTTY9B testis-specific transcript, Y-linked 9B (non-protein coding)
TWIST2 twist family bHLH transcription factor 2
UBE4A ubiquitination factor E4A
UBR1 ubiquitin protein ligase E3 component n-recognin 1
UNC5A unc-5 homolog A (C. elegans)
UNC5B unc-5 homolog B (C. elegans)
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP24 ubiquitin specific peptidase 24
USP3 ubiquitin specific peptidase 3
USP32 ubiquitin specific peptidase 32
USP43 ubiquitin specific peptidase 43
USP8 ubiquitin specific peptidase 8
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae)
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
VWA8 von Willebrand factor A domain containing 8
WAPAL wings apart-like homolog (Drosophila)
WDFY2 WD repeat and FYVE domain containing 2
WNK1 WNK lysine deficient protein kinase 1
WSB2 WD repeat and SOCS box containing 2
ZBED4 zinc finger, BED-type containing 4
ZBTB39 zinc finger and BTB domain containing 39
ZC3H12B zinc finger CCCH-type containing 12B
ZCCHC8 zinc finger, CCHC domain containing 8
ZDHHC11 zinc finger, DHHC-type containing 11
ZFP91-CNTF ZFP91-CNTF readthrough (NMD candidate)
ZNF202 zinc finger protein 202
ZNF264 zinc finger protein 264
ZNF286A zinc finger protein 286A
ZNF304 zinc finger protein 304
ZNF324 zinc finger protein 324
ZNF460 zinc finger protein 460
ZNF584 zinc finger protein 584
ZNF592 zinc finger protein 592
ZNF664 zinc finger protein 664
ZNF749 zinc finger protein 749
ZNF792 zinc finger protein 792
ZPBP zona pellucida binding protein
ZPR1 ZPR1 zinc finger
ZSCAN12P1 zinc finger and SCAN domain containing 12 pseudogene 1
ZSCAN20 zinc finger and SCAN domain containing 20
ZSCAN22 zinc finger and SCAN domain containing 22

low expression

Symbol Name
CTBP1 C-terminal binding protein 1
ETAA1 Ewing tumor-associated antigen 1
FANCF Fanconi anemia, complementation group F
HAUS3 HAUS augmin-like complex, subunit 3
NELFA negative elongation factor complex member A
RWDD4 RWD domain containing 4
ZCRB1 zinc finger CCHC-type and RNA binding motif 1