Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7863-01A-11R-2232-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

358 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7863-01A-11R-2232-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACAA1 acetyl-CoA acyltransferase 1
ACLY ATP citrate lyase
ACOT11 acyl-CoA thioesterase 11
ACRV1 acrosomal vesicle protein 1
ACY1 aminoacylase 1
ADAP2 ArfGAP with dual PH domains 2
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKNAD1 AKNA domain containing 1
ALAS1 5'-aminolevulinate synthase 1
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALOX15B arachidonate 15-lipoxygenase, type B
AMD1 adenosylmethionine decarboxylase 1
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKRD31 ankyrin repeat domain 31
AOX2P aldehyde oxidase 2 pseudogene
AP3B1 adaptor-related protein complex 3, beta 1 subunit
APC2 adenomatosis polyposis coli 2
APEH acylaminoacyl-peptide hydrolase
ARHGAP5-AS1 ARHGAP5 antisense RNA 1 (head to head)
ARHGEF37 Rho guanine nucleotide exchange factor (GEF) 37
ARL10 ADP-ribosylation factor-like 10
ARL4D ADP-ribosylation factor-like 4D
ASAH2B N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B
ATG10 autophagy related 10
AVL9 AVL9 homolog (S. cerevisiase)
AZI2 5-azacytidine induced 2
B3GALTL beta 1,3-galactosyltransferase-like
BAIAP2L2 BAI1-associated protein 2-like 2
BCAP29 B-cell receptor-associated protein 29
BMP2K BMP2 inducible kinase
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BZW1 basic leucine zipper and W2 domains 1
C10ORF76 chromosome 10 open reading frame 76
C16ORF72 chromosome 16 open reading frame 72
C7ORF25 chromosome 7 open reading frame 25
CA2 carbonic anhydrase II
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CASP14 caspase 14, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CATSPERB catsper channel auxiliary subunit beta
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD248 CD248 molecule, endosialin
CDA cytidine deaminase
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDK13 cyclin-dependent kinase 13
CDX4 caudal type homeobox 4
CLCA2 chloride channel accessory 2
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
CPNE3 copine III
CSNK1A1 casein kinase 1, alpha 1
CSNK1A1L casein kinase 1, alpha 1-like
CT55 cancer/testis antigen 55
CYCS cytochrome c, somatic
CYTH3 cytohesin 3
DACH2 dachshund family transcription factor 2
DAO D-amino-acid oxidase
DBNL drebrin-like
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DEFB103B defensin, beta 103B
DFNA5 deafness, autosomal dominant 5
DHRS7 dehydrogenase/reductase (SDR family) member 7
DKFZP779M0652 uncharacterized DKFZp779M0652
DLD dihydrolipoamide dehydrogenase
DOCK6 dedicator of cytokinesis 6
DPYSL4 dihydropyrimidinase-like 4
DSC2 desmocollin 2
DSG1 desmoglein 1
DUSP18 dual specificity phosphatase 18
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
EAF1 ELL associated factor 1
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF4H eukaryotic translation initiation factor 4H
ELL2 elongation factor, RNA polymerase II, 2
ENAH enabled homolog (Drosophila)
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EPGN epithelial mitogen
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM126A family with sequence similarity 126, member A
FAM183B acyloxyacyl hydrolase (neutrophil)
FAM220A family with sequence similarity 220, member A
FAM45A family with sequence similarity 45, member A
FAM45B family with sequence similarity 45, member A pseudogene
FAM83C family with sequence similarity 83, member C
FAM86DP family with sequence similarity 86, member D, pseudogene
FAM98A family with sequence similarity 98, member A
FBLIM1 filamin binding LIM protein 1
FER fer (fps/fes related) tyrosine kinase
FLNB filamin B, beta
FMNL2 formin-like 2
FNIP2 folliculin interacting protein 2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FSCN1 fascin actin-bundling protein 1
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GAGE1 G antigen 1
GAGE10 G antigen 10
GAGE2B G antigen 2B
GARS glycyl-tRNA synthetase
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GGACT gamma-glutamylamine cyclotransferase
GJB2 gap junction protein, beta 2, 26kDa
GJB6 gap junction protein, beta 6, 30kDa
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GOLGA4 golgin A4
GOLGA7B golgin A7 family, member B
GPNMB glycoprotein (transmembrane) nmb
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
GSDMA gasdermin A
HERPUD2 HERPUD family member 2
HEXA-AS1 HEXA antisense RNA 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HK2 hexokinase 2
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HOMER1 homer scaffolding protein 1
HOXA4 homeobox A4
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
HUS1 HUS1 checkpoint homolog (S. pombe)
IL13RA1 interleukin 13 receptor, alpha 1
IL1RL2 interleukin 1 receptor-like 2
IL4R interleukin 4 receptor
INGX inhibitor of growth family, X-linked, pseudogene
IQCF5 IQ motif containing F5
IQCJ IQ motif containing J
IVL involucrin
KANK1 KN motif and ankyrin repeat domains 1
KIAA1598
KIAA1919 KIAA1919
KIF5B kinesin family member 5B
KLHL18 kelch-like family member 18
KLHL35 kelch-like family member 35
KLHL7 kelch-like family member 7
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRT6C keratin 6C, type II
KRT75 keratin 75, type II
LAD1 ladinin 1
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LIMA1 LIM domain and actin binding 1
LINC00032 long intergenic non-protein coding RNA 32
LINC00696 long intergenic non-protein coding RNA 696
LINC01550 long intergenic non-protein coding RNA 1550
LIPG lipase, endothelial
LOC100134868 uncharacterized LOC100134868
LRRC37A3 leucine rich repeat containing 37, member A3
LTB4R2 leukotriene B4 receptor 2
LURAP1L leucine rich adaptor protein 1-like
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGEA1 melanoma antigen family A1
MAGEB1 melanoma antigen family B1
MALT1 MALT1 paracaspase
MAPK14 mitogen-activated protein kinase 14
MAPK6 mitogen-activated protein kinase 6
MAT1A methionine adenosyltransferase I, alpha
MBD1 methyl-CpG binding domain protein 1
MCF2L2 MCF.2 cell line derived transforming sequence-like 2
MED14 mediator complex subunit 14
MEFV Mediterranean fever
MFAP3L microfibrillar-associated protein 3-like
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MLH3 mutL homolog 3
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MPZL2 myelin protein zero-like 2
MRPL32 mitochondrial ribosomal protein L32
MSMO1 methylsterol monooxygenase 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYBPHL myosin binding protein H-like
MYD88 myeloid differentiation primary response 88
MYO1D myosin ID
MYO5A myosin VA (heavy chain 12, myoxin)
NABP1 nucleic acid binding protein 1
NBPF10 neuroblastoma breakpoint family, member 10
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NEFL neurofilament, light polypeptide
NELL2 NEL-like 2 (chicken)
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFE2 nuclear factor, erythroid 2
NIPAL2 NIPA-like domain containing 2
NKIRAS1 NFKB inhibitor interacting Ras-like 1
NME6 NME/NM23 nucleoside diphosphate kinase 6
NMT2 N-myristoyltransferase 2
NOP14-AS1 NOP14 antisense RNA 1
NOTO notochord homeobox
NRBF2 nuclear receptor binding factor 2
NUDCD3 NudC domain containing 3
NXF1 nuclear RNA export factor 1
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OR10H1 olfactory receptor, family 10, subfamily H, member 1
OR10H5 olfactory receptor, family 10, subfamily H, member 5
OR10Q1 olfactory receptor, family 10, subfamily Q, member 1
OR2T2 olfactory receptor, family 2, subfamily T, member 2
OR2W3 olfactory receptor, family 2, subfamily W, member 3
OR5M1 olfactory receptor, family 5, subfamily M, member 1
OR9I1 olfactory receptor, family 9, subfamily I, member 1
OSBPL3 oxysterol binding protein-like 3
OXSR1 oxidative stress responsive 1
PAEP progestagen-associated endometrial protein
PAGE1 P antigen family, member 1 (prostate associated)
PAGE2B P antigen family, member 2B
PANK3 pantothenate kinase 3
PAQR5 progestin and adipoQ receptor family member V
PCDHGC5 protocadherin gamma subfamily C, 5
PDCD6IP programmed cell death 6 interacting protein
PDE8A phosphodiesterase 8A
PDGFA platelet-derived growth factor alpha polypeptide
PHF11 PHD finger protein 11
PHF14 PHD finger protein 14
PHF7 PHD finger protein 7
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PLA2G2F phospholipase A2, group IIF
PLA2G4E phospholipase A2, group IVE
PLA2G4F phospholipase A2, group IVF
PLD2 phospholipase D2
PLEKHA8 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
PLEKHA8P1 pleckstrin homology domain containing, family A member 8 pseudogene 1
PLK2 polo-like kinase 2
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PNLDC1 poly(A)-specific ribonuclease (PARN)-like domain containing 1
PNPLA8 patatin-like phospholipase domain containing 8
POLN polymerase (DNA directed) nu
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPIAL4C peptidylprolyl isomerase A (cyclophilin A)-like 4C
PPIF peptidylprolyl isomerase F
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma
PPP4R1 protein phosphatase 4, regulatory subunit 1
PRDM4 PR domain containing 4
PRICKLE2 prickle homolog 2 (Drosophila)
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRMT3 protein arginine methyltransferase 3
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PTEN phosphatase and tensin homolog
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional)
PTK6 protein tyrosine kinase 6
PWRN1 Prader-Willi region non-protein coding RNA 1
RAB3D RAB3D, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD50 RAD50 homolog (S. cerevisiae)
RALBP1 ralA binding protein 1
RASA4CP RAS p21 protein activator 4C, pseudogene
RBAK RB-associated KRAB zinc finger
RBM45 RNA binding motif protein 45
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
REXO2 RNA exonuclease 2
RFTN1 raftlin, lipid raft linker 1
RGS20 regulator of G-protein signaling 20
RIMS3 regulating synaptic membrane exocytosis 3
RIOK2 RIO kinase 2
RNASE13 ribonuclease, RNase A family, 13 (non-active)
RNF216 ring finger protein 216
RNF216P1 ring finger protein 216 pseudogene 1
RPP14 ribonuclease P/MRP 14kDa subunit
S100A7 S100 calcium binding protein A7
S100A7A S100 calcium binding protein A7A
SBDS Shwachman-Bodian-Diamond syndrome
SCAPER S-phase cyclin A-associated protein in the ER
SCN3B sodium channel, voltage gated, type III beta subunit
SCRN1 secernin 1
SEPT7 septin 7
SEPT8 septin 8
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SH3BP2 SH3-domain binding protein 2
SHROOM2 shroom family member 2
SIAE sialic acid acetylesterase
SKAP2 src kinase associated phosphoprotein 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC22A14 solute carrier family 22, member 14
SLC22A23 solute carrier family 22, member 23
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC25A30 solute carrier family 25, member 30
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC35E1 solute carrier family 35, member E1
SLC38A1 solute carrier family 38, member 1
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SMIM14 small integral membrane protein 14
SMIM21 small integral membrane protein 21
SNAR-G1 small ILF3/NF90-associated RNA G1
SNX10 sorting nexin 10
SNX13 sorting nexin 13
SOWAHC sosondowah ankyrin repeat domain family member C
SOX30 SRY (sex determining region Y)-box 30
SPESP1 sperm equatorial segment protein 1
SPRYD7 SPRY domain containing 7
SQLE squalene epoxidase
SSX4 synovial sarcoma, X breakpoint 4
STRIP1 striatin interacting protein 1
STXBP5 syntaxin binding protein 5 (tomosyn)
SV2C synaptic vesicle glycoprotein 2C
SZT2 seizure threshold 2 homolog (mouse)
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TBC1D3 TBC1 domain family, member 3
TCP11 t-complex 11, testis-specific
THBD thrombomodulin
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TM4SF19 transmembrane 4 L six family member 19
TM4SF20 transmembrane 4 L six family member 20
TMEM154 transmembrane protein 154
TMEM184A transmembrane protein 184A
TMIE transmembrane inner ear
TMOD2 tropomodulin 2 (neuronal)
TMPRSS13 transmembrane protease, serine 13
TPRXL tetra-peptide repeat homeobox-like
TRA2A transformer 2 alpha homolog (Drosophila)
TRIM36 tripartite motif containing 36
TRIM58 tripartite motif containing 58
TRIP4 thyroid hormone receptor interactor 4
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TTYH3 tweety family member 3
TUBA1C tubulin, alpha 1c
TUBB2A tubulin, beta 2A class IIa
TUBB3 tubulin, beta 3 class III
TXNRD3NB thioredoxin reductase 3 neighbor
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2E2 ubiquitin-conjugating enzyme E2E 2
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1
USP17L2 ubiquitin specific peptidase 17-like family member 2
USP45 ubiquitin specific peptidase 45
WDR36 WD repeat domain 36
WDR47 WD repeat domain 47
WISP1 WNT1 inducible signaling pathway protein 1
XKR9 XK, Kell blood group complex subunit-related family, member 9
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZIM3 zinc finger, imprinted 3
ZMAT5 zinc finger, matrin-type 5
ZNF283 zinc finger protein 283
ZNF319 zinc finger protein 319
ZNF35 zinc finger protein 35
ZNF354A zinc finger protein 354A
ZNF416 zinc finger protein 416
ZNF562 zinc finger protein 562
ZNF662 zinc finger protein 662
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase

low expression

Symbol Name
C7ORF60 chromosome 7 open reading frame 60
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9)
MRPL10 mitochondrial ribosomal protein L10
PICK1 protein interacting with PRKCA 1
SLC35B1 solute carrier family 35, member B1
SP2 Sp2 transcription factor
SPOP speckle-type POZ protein
TMUB2 transmembrane and ubiquitin-like domain containing 2
TP53BP1 tumor protein p53 binding protein 1
UBE2Z ubiquitin-conjugating enzyme E2Z
UBXN2B UBX domain protein 2B
ZFP69 ZFP69 zinc finger protein
ZNF140 zinc finger protein 140
ZNF555 zinc finger protein 555
ZSCAN20 zinc finger and SCAN domain containing 20