Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DJ-01A-11R-A30B-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

237 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DJ-01A-11R-A30B-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACYP1 acylphosphatase 1, erythrocyte (common) type
ADAM8 ADAM metallopeptidase domain 8
ADRB2 adrenoceptor beta 2, surface
AFAP1L1 actin filament associated protein 1-like 1
AMIGO2 adhesion molecule with Ig-like domain 2
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
AREG amphiregulin
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASS1 argininosuccinate synthase 1
AVPI1 arginine vasopressin-induced 1
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BATF2 basic leucine zipper transcription factor, ATF-like 2
BMP2 bone morphogenetic protein 2
BPGM 2,3-bisphosphoglycerate mutase
BREA2 breast cancer estrogen-induced apoptosis 2
C12ORF71 chromosome 12 open reading frame 71
C12ORF75 chromosome 12 open reading frame 75
C16ORF52 chromosome 16 open reading frame 52
C1ORF74 chromosome 1 open reading frame 74
C20ORF144 chromosome 20 open reading frame 144
C20ORF197 chromosome 20 open reading frame 197
C3ORF35 chromosome 3 open reading frame 35
C3ORF62 chromosome 3 open reading frame 62
C6ORF10 chromosome 6 open reading frame 10
C9ORF85 chromosome 9 open reading frame 85
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2
CARD17 caspase recruitment domain family, member 17
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCDC66 coiled-coil domain containing 66
CDCP1 CUB domain containing protein 1
CDRT1 CMT1A duplicated region transcript 1
CHMP5 charged multivesicular body protein 5
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLCF1 cardiotrophin-like cytokine factor 1
COL7A1 collagen, type VII, alpha 1
CRMP1 collapsin response mediator protein 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CSNK1E casein kinase 1, epsilon
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DCTD dCMP deaminase
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DEPDC7 DEP domain containing 7
DGKA diacylglycerol kinase, alpha 80kDa
DLG4 discs, large homolog 4 (Drosophila)
DLL1 delta-like 1 (Drosophila)
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
DSE dermatan sulfate epimerase
DUSP6 dual specificity phosphatase 6
DUSP7 dual specificity phosphatase 7
EDN1 endothelin 1
EFNB3 ephrin-B3
EHD4 EH-domain containing 4
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EQTN equatorin, sperm acrosome associated
EREG epiregulin
ERRFI1 ERBB receptor feedback inhibitor 1
ETHE1 ethylmalonic encephalopathy 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EXOSC9 exosome component 9
F2RL1 coagulation factor II (thrombin) receptor-like 1
FBXO11 F-box protein 11
FBXW10 F-box and WD repeat domain containing 10
FCHSD1 FCH and double SH3 domains 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FFAR2 free fatty acid receptor 2
FLJ12825 uncharacterized LOC440101
FOSL1 FOS-like antigen 1
FOXN2 forkhead box N2
FST follistatin
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GJB3 gap junction protein, beta 3, 31kDa
GJB4 gap junction protein, beta 4, 30.3kDa
GLYCTK glycerate kinase
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GRXCR2 glutaredoxin, cysteine rich 2
GYLTL1B glycosyltransferase-like 1B
HAR1A highly accelerated region 1A (non-protein coding)
HBEGF heparin-binding EGF-like growth factor
HCAR2 hydroxycarboxylic acid receptor 2
HEATR9 HEAT repeat containing 9
HES7 hes family bHLH transcription factor 7
HEXIM1 hexamethylene bis-acetamide inducible 1
HINT1 histidine triad nucleotide binding protein 1
HIST1H2BH histone cluster 1, H2bh
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HLA-F major histocompatibility complex, class I, F
HLA-L major histocompatibility complex, class I, L (pseudogene)
HORMAD1 HORMA domain containing 1
HRH1 histamine receptor H1
IER3 immediate early response 3
IFITM3 interferon induced transmembrane protein 3
IFNE interferon, epsilon
IL11 interleukin 11
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL20 interleukin 20
IL23A interleukin 23, alpha subunit p19
IL24 interleukin 24
IL3 interleukin 3
IL36G interleukin 36, gamma
INHBA inhibin, beta A
IRAK2 interleukin-1 receptor-associated kinase 2
IRGC immunity-related GTPase family, cinema
IZUMO1 izumo sperm-egg fusion 1
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2
KCTD11 potassium channel tetramerization domain containing 11
KCTD14 potassium channel tetramerization domain containing 14
KDSR 3-ketodihydrosphingosine reductase
KIAA0040 KIAA0040
KIFC3 kinesin family member C3
KLF6 Kruppel-like factor 6
KYNU kynureninase
LCAT lecithin-cholesterol acyltransferase
LGALS9B lectin, galactoside-binding, soluble, 9B
LOC152225 uncharacterized LOC152225
LRRC8A leucine rich repeat containing 8 family, member A
MACROD2 MACRO domain containing 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGOH mago-nashi homolog, proliferation-associated (Drosophila)
MAP7D1 MAP7 domain containing 1
MBD1 methyl-CpG binding domain protein 1
MCL1 myeloid cell leukemia 1
MFSD2A major facilitator superfamily domain containing 2A
MIR22HG MIR22 host gene
MMP10 matrix metallopeptidase 10
MPHOSPH6 M-phase phosphoprotein 6
MST1R macrophage stimulating 1 receptor
MTAP methylthioadenosine phosphorylase
NCF2 neutrophil cytosolic factor 2
NET1 neuroepithelial cell transforming 1
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NGDN neuroguidin, EIF4E binding protein
NRADDP neurotrophin receptor associated death domain, pseudogene
NRBP1 nuclear receptor binding protein 1
NT5E 5'-nucleotidase, ecto (CD73)
OR2L3 olfactory receptor, family 2, subfamily L, member 3
OR2T8 olfactory receptor, family 2, subfamily T, member 8
OR2W3 olfactory receptor, family 2, subfamily W, member 3
OXSR1 oxidative stress responsive 1
PA2G4P4 proliferation-associated 2G4 pseudogene 4
PAQR6 progestin and adipoQ receptor family member VI
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PLA2G2F phospholipase A2, group IIF
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLK3 polo-like kinase 3
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PPARD peroxisome proliferator-activated receptor delta
PPIAL4E peptidylprolyl isomerase A (cyclophilin A)-like 4E
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRDM1 PR domain containing 1, with ZNF domain
PRNP prion protein
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPRE protein tyrosine phosphatase, receptor type, E
RALGDS ral guanine nucleotide dissociation stimulator
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RELL2 RELT-like 2
RIMKLB ribosomal modification protein rimK-like family member B
RNF145 ring finger protein 145
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SDC4 syndecan 4
SELK selenoprotein K
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13
SLC22A14 solute carrier family 22, member 14
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SMAD7 SMAD family member 7
SNHG15 small nucleolar RNA host gene 15
SNORA1 small nucleolar RNA, H/ACA box 1
SNORA20 small nucleolar RNA, H/ACA box 20
SNORA65 small nucleolar RNA, H/ACA box 65
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
SOD2 superoxide dismutase 2, mitochondrial
SPRED3 sprouty-related, EVH1 domain containing 3
SREK1IP1 SREK1-interacting protein 1
SSMEM1 serine-rich single-pass membrane protein 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD5 StAR-related lipid transfer (START) domain containing 5
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TAS2R43 taste receptor, type 2, member 43
TGFBR1 transforming growth factor, beta receptor 1
TICAM1 toll-like receptor adaptor molecule 1
TJP2 tight junction protein 2
TMCC3 transmembrane and coiled-coil domain family 3
TMCO2 transmembrane and coiled-coil domains 2
TMPRSS11D transmembrane protease, serine 11D
TNF tumor necrosis factor
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAF3IP2 TRAF3 interacting protein 2
TRAPPC4 trafficking protein particle complex 4
TRIM40 tripartite motif containing 40
TRIM58 tripartite motif containing 58
TSSK3 testis-specific serine kinase 3
U2AF1 U2 small nuclear RNA auxiliary factor 1
UBA7 ubiquitin-like modifier activating enzyme 7
UBAP1 ubiquitin associated protein 1
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFC vascular endothelial growth factor C
VNN3 vanin 3
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZBED2 zinc finger, BED-type containing 2
ZBTB43 zinc finger and BTB domain containing 43
ZFP36L2 ZFP36 ring finger protein-like 2
ZPLD1 zona pellucida-like domain containing 1

low expression

Symbol Name
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
FAM134A family with sequence similarity 134, member A
GIGYF2 GRB10 interacting GYF protein 2
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
THADA thyroid adenoma associated