Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6873-01A-11R-1873-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

378 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6873-01A-11R-1873-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10
ACOT2 acyl-CoA thioesterase 2
ACTN1 actinin, alpha 1
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ACTRT3 actin-related protein T3
ADRBK2 adrenergic, beta, receptor kinase 2
AJUBA ajuba LIM protein
AKAP3 A kinase (PRKA) anchor protein 3
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ARHGAP29 Rho GTPase activating protein 29
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARL10 ADP-ribosylation factor-like 10
ASB7 ankyrin repeat and SOCS box containing 7
ASPHD2 aspartate beta-hydroxylase domain containing 2
ATXN3 ataxin 3
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BEND3 BEN domain containing 3
BEND6 BEN domain containing 6
BNC1 basonuclin 1
BRCA1 breast cancer 1, early onset
BRD9 bromodomain containing 9
BRPF1 bromodomain and PHD finger containing, 1
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
C11ORF87 chromosome 11 open reading frame 87
C12ORF4 chromosome 12 open reading frame 4
C14ORF169 chromosome 14 open reading frame 169
C16ORF62 chromosome 16 open reading frame 62
C17ORF85 chromosome 17 open reading frame 85
C22ORF24 chromosome 22 open reading frame 24
C8ORF37 chromosome 8 open reading frame 37
C9ORF43 chromosome 9 open reading frame 43
CABIN1 calcineurin binding protein 1
CARD10 caspase recruitment domain family, member 10
CBWD5 COBW domain containing 5
CCAR1 cell division cycle and apoptosis regulator 1
CCBE1 collagen and calcium binding EGF domains 1
CCDC117 coiled-coil domain containing 117
CCDC127 coiled-coil domain containing 127
CCDC18 coiled-coil domain containing 18
CCDC51 coiled-coil domain containing 51
CCDC66 coiled-coil domain containing 66
CCDC71 coiled-coil domain containing 71
CCND2 cyclin D2
CD200R1L CD200 receptor 1-like
CDC25A cell division cycle 25A
CDCA4 cell division cycle associated 4
CDCP1 CUB domain containing protein 1
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDR2L cerebellar degeneration-related protein 2-like
CEP128 centrosomal protein 128kDa
CFL1 cofilin 1 (non-muscle)
CHD8 chromodomain helicase DNA binding protein 8
CLSPN claspin
CNOT10 CCR4-NOT transcription complex, subunit 10
CNTF ciliary neurotrophic factor
COA7 cytochrome c oxidase assembly factor 7 (putative)
COL18A1-AS1 COL18A1 antisense RNA 1
COL7A1 collagen, type VII, alpha 1
COPS7A COP9 signalosome subunit 7A
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CSMD2 CUB and Sushi multiple domains 2
CSNK1G2-AS1 CSNK1G2 antisense RNA 1
CSPG4 chondroitin sulfate proteoglycan 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DACT1 dishevelled-binding antagonist of beta-catenin 1
DCAF4 DDB1 and CUL4 associated factor 4
DCBLD1 discoidin, CUB and LCCL domain containing 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNM3 dynamin 3
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DPH1 diphthamide biosynthesis 1
DPP3 dipeptidyl-peptidase 3
DSEL dermatan sulfate epimerase-like
DUSP7 dual specificity phosphatase 7
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EIF1AD eukaryotic translation initiation factor 1A domain containing
EIF3C eukaryotic translation initiation factor 3, subunit C
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ELP6 elongator acetyltransferase complex subunit 6
ERCC6 excision repair cross-complementation group 6
ESYT1 extended synaptotagmin-like protein 1
EVC Ellis van Creveld protein
EXD2 exonuclease 3'-5' domain containing 2
EXOC5 exocyst complex component 5
EXOG endo/exonuclease (5'-3'), endonuclease G-like
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM21A family with sequence similarity 21, member A
FANCM Fanconi anemia, complementation group M
FCF1 FCF1 rRNA-processing protein
FHAD1 forkhead-associated (FHA) phosphopeptide binding domain 1
FHOD1 formin homology 2 domain containing 1
FKBP5 FK506 binding protein 5
FOXL1 forkhead box L1
FOXM1 forkhead box M1
FRMD5 FERM domain containing 5
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GDAP1 ganglioside induced differentiation associated protein 1
GDNF glial cell derived neurotrophic factor
GJC1 gap junction protein, gamma 1, 45kDa
GLB1 galactosidase, beta 1
GLT8D1 glycosyltransferase 8 domain containing 1
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GOPC golgi-associated PDZ and coiled-coil motif containing
GORASP1 golgi reassembly stacking protein 1, 65kDa
GPN2 GPN-loop GTPase 2
GPSM2 G-protein signaling modulator 2
GRIA3 glutamate receptor, ionotropic, AMPA 3
GUCD1 guanylyl cyclase domain containing 1
HACD2 3-hydroxyacyl-CoA dehydratase 2
HDAC9 histone deacetylase 9
HEATR4 HEAT repeat containing 4
HIST1H4L histone cluster 1, H4l
HIST3H3 histone cluster 3, H3
HLA-C major histocompatibility complex, class I, C
HOXC4 homeobox C4
HOXC5 homeobox C5
HPS4 Hermansky-Pudlak syndrome 4
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone
HTT huntingtin
ICAM5 intercellular adhesion molecule 5, telencephalin
IFRD2 interferon-related developmental regulator 2
IGF1R insulin-like growth factor 1 receptor
IL17RE interleukin 17 receptor E
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
IP6K1 inositol hexakisphosphate kinase 1
IP6K2 inositol hexakisphosphate kinase 2
IPO4 importin 4
IRGM immunity-related GTPase family, M
IRX1 iroquois homeobox 1
IRX4 iroquois homeobox 4
ITGB4 integrin, beta 4
ITPK1-AS1 ITPK1 antisense RNA 1
JAG2 jagged 2
KANK4 KN motif and ankyrin repeat domains 4
KAT5 K(lysine) acetyltransferase 5
KDM2A lysine (K)-specific demethylase 2A
KIAA0586 KIAA0586
KIAA1429 KIAA1429
KLC2 kinesin light chain 2
KPNB1 karyopherin (importin) beta 1
KREMEN1 kringle containing transmembrane protein 1
L3HYPDH L-3-hydroxyproline dehydratase (trans-)
LAMA1 laminin, alpha 1
LAMA3 laminin, alpha 3
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LDHAL6B lactate dehydrogenase A-like 6B
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LHX1 LIM homeobox 1
LINC01555 long intergenic non-protein coding RNA 1555
LOC145474 uncharacterized LOC145474
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRRC28 leucine rich repeat containing 28
LZTR1 leucine-zipper-like transcription regulator 1
MAGED4B melanoma antigen family D4B
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MCM4 minichromosome maintenance complex component 4
MEF2A myocyte enhancer factor 2A
MESDC1 mesoderm development candidate 1
METTL3 methyltransferase like 3
METTL6 methyltransferase like 6
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MKRN2 makorin ring finger protein 2
MLH1 mutL homolog 1
MMP9 matrix metallopeptidase 9
MN1 meningioma (disrupted in balanced translocation) 1
MORF4 mortality factor 4 (pseudogene)
MST1R macrophage stimulating 1 receptor
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUS81 MUS81 structure-specific endonuclease subunit
MYBBP1A MYB binding protein (P160) 1a
MYO3B myosin IIIB
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
NBN nibrin
NCAPG non-SMC condensin I complex, subunit G
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
NEK4 NIMA-related kinase 4
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NID1 nidogen 1
NME6 NME/NM23 nucleoside diphosphate kinase 6
NOL9 nucleolar protein 9
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP2 NOP2 nucleolar protein
NOP9 NOP9 nucleolar protein
NRDE2 NRDE-2, necessary for RNA interference, domain containing
NUBPL nucleotide binding protein-like
NUTM2A NUT family member 2A
NUTM2D NUT family member 2D
NXPH2 neurexophilin 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR10Q1 olfactory receptor, family 10, subfamily Q, member 1
OR2L1P olfactory receptor, family 2, subfamily L, member 1 pseudogene
OR2M3 olfactory receptor, family 2, subfamily M, member 3
OR52B6 olfactory receptor, family 52, subfamily B, member 6
OR5E1P olfactory receptor, family 5, subfamily E, member 1 pseudogene
OR6M1 olfactory receptor, family 6, subfamily M, member 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
ORC1 origin recognition complex, subunit 1
OSBPL10 oxysterol binding protein-like 10
OTUD6B OTU domain containing 6B
OXSR1 oxidative stress responsive 1
PACS1 phosphofurin acidic cluster sorting protein 1
PADI4 peptidyl arginine deiminase, type IV
PARP11 poly (ADP-ribose) polymerase family, member 11
PARP2 poly (ADP-ribose) polymerase 2
PATL1 protein associated with topoisomerase II homolog 1 (yeast)
PBRM1 polybromo 1
PCDHGB5 protocadherin gamma subfamily B, 5
PCNXL3 pecanex-like 3 (Drosophila)
PCSK9 proprotein convertase subtilisin/kexin type 9
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDE7A phosphodiesterase 7A
PFAS phosphoribosylformylglycinamidine synthase
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PGBD3 piggyBac transposable element derived 3
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PITPNB phosphatidylinositol transfer protein, beta
PLEC plectin
PLEK2 pleckstrin 2
PML promyelocytic leukemia
PNMA1 paraneoplastic Ma antigen 1
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP4R2 protein phosphatase 4, regulatory subunit 2
PRICKLE2 prickle homolog 2 (Drosophila)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT5 protein arginine methyltransferase 5
PRO0628 uncharacterized LOC29053
PRPF8 pre-mRNA processing factor 8
PRR11 proline rich 11
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PTCHD2 patched domain containing 2
QRICH1 glutamine-rich 1
RAB1B RAB1B, member RAS oncogene family
RABL2B RAB, member of RAS oncogene family-like 2B
RAD51AP1 RAD51 associated protein 1
RBM25 RNA binding motif protein 25
RCE1 Ras converting CAAX endopeptidase 1
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RFC1 replication factor C (activator 1) 1, 145kDa
RNASE10 ribonuclease, RNase A family, 10 (non-active)
RPE65 retinal pigment epithelium-specific protein 65kDa
RPUSD3 RNA pseudouridylate synthase domain containing 3
RRP1B ribosomal RNA processing 1B
RTP3 receptor (chemosensory) transporter protein 3
SART1 squamous cell carcinoma antigen recognized by T cells
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCG5 secretogranin V
SDF2L1 stromal cell-derived factor 2-like 1
SEC13 SEC13 homolog (S. cerevisiae)
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae)
SEC23A Sec23 homolog A (S. cerevisiae)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD2 SET domain containing 2
SETD5 SET domain containing 5
SF3B2 splicing factor 3b, subunit 2, 145kDa
SH3GL3 SH3-domain GRB2-like 3
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC35G6 solute carrier family 35, member G6
SLC38A5 solute carrier family 38, member 5
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC7A5P1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLFN11 schlafen family member 11
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMIM21 small integral membrane protein 21
SNAI2 snail family zinc finger 2
SNORA6 small nucleolar RNA, H/ACA box 6
SNRK SNF related kinase
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa
SPDL1 spindle apparatus coiled-coil protein 1
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPHK1 sphingosine kinase 1
SRPX sushi-repeat containing protein, X-linked
SRR serine racemase
SRRD SRR1 domain containing
STON2 stonin 2
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
STX10 syntaxin 10
SUMF1 sulfatase modifying factor 1
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
SYT12 synaptotagmin XII
TAAR5 trace amine associated receptor 5
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TANGO6 transport and golgi organization 6 homolog (Drosophila)
TAS2R3 taste receptor, type 2, member 3
TAS2R30 taste receptor, type 2, member 30
TAS2R60 taste receptor, type 2, member 60
TECPR2 tectonin beta-propeller repeat containing 2
TERC telomerase RNA component
TFIP11 tuftelin interacting protein 11
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGS1 trimethylguanosine synthase 1
TH tyrosine hydroxylase
THBS1 thrombospondin 1
TIGAR TP53 induced glycolysis regulatory phosphatase
TLL1 tolloid-like 1
TMEM229B transmembrane protein 229B
TMEM244 transmembrane protein 244
TMEM43 transmembrane protein 43
TMPPE transmembrane protein with metallophosphoesterase domain
TOP3B topoisomerase (DNA) III beta
TOX thymocyte selection-associated high mobility group box
TPI1P2 triosephosphate isomerase 1 pseudogene 2
TPST2 tyrosylprotein sulfotransferase 2
TRIM36 tripartite motif containing 36
TRIO trio Rho guanine nucleotide exchange factor
TRIP13 thyroid hormone receptor interactor 13
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSPAN5 tetraspanin 5
TTC23 tetratricopeptide repeat domain 23
TTC8 tetratricopeptide repeat domain 8
TTLL11 tubulin tyrosine ligase-like family member 11
TTLL5 tubulin tyrosine ligase-like family member 5
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UBR1 ubiquitin protein ligase E3 component n-recognin 1
UCN2 urocortin 2
UHRF1 ubiquitin-like with PHD and ring finger domains 1
USP24 ubiquitin specific peptidase 24
USP48 ubiquitin specific peptidase 48
UTS2 urotensin 2
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
VPRBP Vpr (HIV-1) binding protein
WDHD1 WD repeat and HMG-box DNA binding protein 1
WDR6 WD repeat domain 6
WDR82 WD repeat domain 82
WNT7A wingless-type MMTV integration site family, member 7A
YDJC YdjC homolog (bacterial)
YIF1A Yip1 interacting factor homolog A (S. cerevisiae)
YY1 YY1 transcription factor
ZBTB8A zinc finger and BTB domain containing 8A
ZC3H14 zinc finger CCCH-type containing 14
ZC4H2 zinc finger, C4H2 domain containing
ZCCHC11 zinc finger, CCHC domain containing 11
ZFHX4 zinc finger homeobox 4
ZFP90 ZFP90 zinc finger protein
ZFP91 ZFP91 zinc finger protein
ZFYVE26 zinc finger, FYVE domain containing 26
ZNF197 zinc finger protein 197
ZNF365 zinc finger protein 365
ZNF532 zinc finger protein 532
ZNF608 zinc finger protein 608
ZNF625 zinc finger protein 625
ZNF699 zinc finger protein 699
ZNF788 zinc finger family member 788
ZNRF3 zinc and ring finger 3
ZRANB3 zinc finger, RAN-binding domain containing 3
ZWILCH zwilch kinetochore protein