Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5558-01A-01R-1514-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

285 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5558-01A-01R-1514-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ACE angiotensin I converting enzyme
ACLY ATP citrate lyase
ACRC acidic repeat containing
ACRV1 acrosomal vesicle protein 1
ACTRT3 actin-related protein T3
ADAP2 ArfGAP with dual PH domains 2
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
AGO2 argonaute RISC catalytic component 2
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
AMOTL1 angiomotin like 1
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
ARHGAP32 Rho GTPase activating protein 32
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASB13 ankyrin repeat and SOCS box containing 13
ATG2A autophagy related 2A
ATP13A3 ATPase type 13A3
BCO2 beta-carotene oxygenase 2
BMP2K BMP2 inducible kinase
BTBD11 BTB (POZ) domain containing 11
C10ORF99 chromosome 10 open reading frame 99
C18ORF8 chromosome 18 open reading frame 8
CARD17 caspase recruitment domain family, member 17
CARD6 caspase recruitment domain family, member 6
CASP4 caspase 4, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL24 chemokine (C-C motif) ligand 24
CD163 CD163 molecule
CD163L1 CD163 molecule-like 1
CD209 CD209 molecule
CD300E CD300e molecule
CD3EAP CD3e molecule, epsilon associated protein
CEP72 centrosomal protein 72kDa
CHD7 chromodomain helicase DNA binding protein 7
CLPTM1 cleft lip and palate associated transmembrane protein 1
CLUH clustered mitochondria (cluA/CLU1) homolog
CMA1 chymase 1, mast cell
CMIP c-Maf inducing protein
COL12A1 collagen, type XII, alpha 1
CPA3 carboxypeptidase A3 (mast cell)
CRLF2 cytokine receptor-like factor 2
CTSG cathepsin G
CTSL cathepsin L
CWF19L2 CWF19-like 2, cell cycle control (S. pombe)
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae)
DDIAS DNA damage-induced apoptosis suppressor
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DIAPH1 diaphanous-related formin 1
DKC1 dyskeratosis congenita 1, dyskerin
DLL1 delta-like 1 (Drosophila)
DOT1L DOT1-like histone H3K79 methyltransferase
DPF2 D4, zinc and double PHD fingers family 2
DSC2 desmocollin 2
DSC3 desmocollin 3
DUOXA1 dual oxidase maturation factor 1
EHD1 EH-domain containing 1
EHD4 EH-domain containing 4
EIF3C eukaryotic translation initiation factor 3, subunit C
EIF4A3 eukaryotic translation initiation factor 4A3
ENDOD1 endonuclease domain containing 1
EPAS1 endothelial PAS domain protein 1
EPGN epithelial mitogen
EPN1 epsin 1
ERCC2 excision repair cross-complementation group 2
ERN1 endoplasmic reticulum to nucleus signaling 1
FAM110C family with sequence similarity 110, member C
FAM183B acyloxyacyl hydrolase (neutrophil)
FAM83A family with sequence similarity 83, member A
FAM83G family with sequence similarity 83, member G
FBLIM1 filamin binding LIM protein 1
FBXO46 F-box protein 46
FOXF2 forkhead box F2
FRMD8 FERM domain containing 8
GAB2 GRB2-associated binding protein 2
GATA2 GATA binding protein 2
GCSAML germinal center-associated, signaling and motility-like
GEMIN5 gem (nuclear organelle) associated protein 5
GLRA4 glycine receptor, alpha 4
GLTPD2 glycolipid transfer protein domain containing 2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GM2A GM2 ganglioside activator
GNPDA1 glucosamine-6-phosphate deaminase 1
GPR157 G protein-coupled receptor 157
GRWD1 glutamate-rich WD repeat containing 1
GUCY2GP guanylate cyclase 2G, pseudogene
HCCS holocytochrome c synthase
HDC histidine decarboxylase
HEPHL1 hephaestin-like 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
ICE1 interactor of little elongation complex ELL subunit 1
IFNA10 interferon, alpha 10
IFNA4 interferon, alpha 4
IGSF21 immunoglobin superfamily, member 21
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL3 interleukin 3
IL36RN interleukin 36 receptor antagonist
IPMK inositol polyphosphate multikinase
IRAK1 interleukin-1 receptor-associated kinase 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCTD21 potassium channel tetramerization domain containing 21
KDM2A lysine (K)-specific demethylase 2A
KIAA0196 KIAA0196
KLC3 kinesin light chain 3
KLK13 kallikrein-related peptidase 13
KLK6 kallikrein-related peptidase 6
KLK7 kallikrein-related peptidase 7
KLK9 kallikrein-related peptidase 9
LARP1 La ribonucleoprotein domain family, member 1
LELP1 late cornified envelope-like proline-rich 1
LHX4 LIM homeobox 4
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
LPCAT1 lysophosphatidylcholine acyltransferase 1
LPIN2 lipin 2
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRP5 low density lipoprotein receptor-related protein 5
LTB4R2 leukotriene B4 receptor 2
LUZP1 leucine zipper protein 1
LYNX1 Ly6/neurotoxin 1
LYPD3 LY6/PLAUR domain containing 3
MACF1 microtubule-actin crosslinking factor 1
MAGEA1 melanoma antigen family A1
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MAST4 microtubule associated serine/threonine kinase family member 4
MBNL3 muscleblind-like splicing regulator 3
MCF2L2 MCF.2 cell line derived transforming sequence-like 2
MED25 mediator complex subunit 25
MEFV Mediterranean fever
MINK1 misshapen-like kinase 1
MMP3 matrix metallopeptidase 3
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E
MTAP methylthioadenosine phosphorylase
MTMR12 myotubularin related protein 12
MTSS1 metastasis suppressor 1
MYBBP1A MYB binding protein (P160) 1a
MYO1B myosin IB
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha
NAV1 neuron navigator 1
NBPF10 neuroblastoma breakpoint family, member 10
NCAPD3 non-SMC condensin II complex, subunit D3
NFRKB nuclear factor related to kappaB binding protein
NIPBL Nipped-B homolog (Drosophila)
NKD2 naked cuticle homolog 2 (Drosophila)
NOP9 NOP9 nucleolar protein
NPC1 Niemann-Pick disease, type C1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NSUN2 NOP2/Sun RNA methyltransferase family, member 2
NUP98 nucleoporin 98kDa
OAF OAF homolog (Drosophila)
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
OR2L1P olfactory receptor, family 2, subfamily L, member 1 pseudogene
OR2T11 olfactory receptor, family 2, subfamily T, member 11 (gene/pseudogene)
OR2W3 olfactory receptor, family 2, subfamily W, member 3
OR9A2 olfactory receptor, family 9, subfamily A, member 2
OSMR oncostatin M receptor
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OTULIN OTU deubiquitinase with linear linkage specificity
P3H2 prolyl 3-hydroxylase 2
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PANX1 pannexin 1
PCDH7 protocadherin 7
PCNXL3 pecanex-like 3 (Drosophila)
PF4 platelet factor 4
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGAM5 phosphoglycerate mutase family member 5
PGLYRP4 peptidoglycan recognition protein 4
PICALM phosphatidylinositol binding clathrin assembly protein
PLA2G2F phospholipase A2, group IIF
PLA2G4E phospholipase A2, group IVE
PLD2 phospholipase D2
PLTP phospholipid transfer protein
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
POU4F3 POU class 4 homeobox 3
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP6R1 protein phosphatase 6, regulatory subunit 1
PRCP prolylcarboxypeptidase (angiotensinase C)
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRKD2 protein kinase D2
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PTBP1 polypyrimidine tract binding protein 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RAB1B RAB1B, member RAS oncogene family
RAB30 RAB30, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RAB38 RAB38, member RAS oncogene family
RASGRP4 RAS guanyl releasing protein 4
RCE1 Ras converting CAAX endopeptidase 1
RDH13 retinol dehydrogenase 13 (all-trans/9-cis)
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RICTOR RPTOR independent companion of MTOR, complex 2
RNF169 ring finger protein 169
RP1L1 retinitis pigmentosa 1-like 1
RREB1 ras responsive element binding protein 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A7A S100 calcium binding protein A7A
SBNO2 strawberry notch homolog 2 (Drosophila)
SCAF1 SR-related CTD-associated factor 1
SCARB1 scavenger receptor class B, member 1
SCYL1 SCY1-like 1 (S. cerevisiae)
SDHAP2 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2
SDR42E1 short chain dehydrogenase/reductase family 42E, member 1
SERINC5 serine incorporator 5
SERPINA13P serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 13, pseudogene
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SF1 splicing factor 1
SH3BP5L SH3-binding domain protein 5-like
SH3PXD2A SH3 and PX domains 2A
SHPK sedoheptulokinase
SIGLEC6 sialic acid binding Ig-like lectin 6
SIK3 SIK family kinase 3
SIX5 SIX homeobox 5
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC10A3 solute carrier family 10, member 3
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC35F2 solute carrier family 35, member F2
SLC38A2 solute carrier family 38, member 2
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
STRN striatin, calmodulin binding protein
SYVN1 synovial apoptosis inhibitor 1, synoviolin
SZT2 seizure threshold 2 homolog (mouse)
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TARS threonyl-tRNA synthetase
TCERG1 transcription elongation regulator 1
TGFB1 transforming growth factor, beta 1
THSD1 thrombospondin, type I, domain containing 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM120B transmembrane protein 120B
TOR1AIP2 torsin A interacting protein 2
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TPSD1 tryptase delta 1
TRAF3IP2 TRAF3 interacting protein 2
TREML1 triggering receptor expressed on myeloid cells-like 1
TRIB1 tribbles pseudokinase 1
TRIM29 tripartite motif containing 29
TRIM58 tripartite motif containing 58
TRIO trio Rho guanine nucleotide exchange factor
TSC22D2 TSC22 domain family, member 2
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)
U2AF2 U2 small nuclear RNA auxiliary factor 2
UBL4A ubiquitin-like 4A
UBR5 ubiquitin protein ligase E3 component n-recognin 5
USP3 ubiquitin specific peptidase 3
USP43 ubiquitin specific peptidase 43
VCL vinculin
XDH xanthine dehydrogenase
ZBED6CL ZBED6 C-terminal like
ZFP91-CNTF ZFP91-CNTF readthrough (NMD candidate)
ZFP92 ZFP92 zinc finger protein
ZNF416 zinc finger protein 416
ZNF426 zinc finger protein 426
ZNF549 zinc finger protein 549
ZNF584 zinc finger protein 584
ZNF710 zinc finger protein 710
ZPR1 ZPR1 zinc finger
ZW10 zw10 kinetochore protein

low expression

Symbol Name
FBXO7 F-box protein 7
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
KANSL1L KAT8 regulatory NSL complex subunit 1-like