Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5149-01A-01R-1514-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

395 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5149-01A-01R-1514-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADRBK1 adrenergic, beta, receptor kinase 1
AGO2 argonaute RISC catalytic component 2
AJAP1 adherens junctions associated protein 1
AK2 adenylate kinase 2
AKAP2 A kinase (PRKA) anchor protein 2
AKIRIN1 akirin 1
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
ANLN anillin, actin binding protein
ANO1 anoctamin 1, calcium activated chloride channel
ANO3 anoctamin 3
AP3B1 adaptor-related protein complex 3, beta 1 subunit
AREG amphiregulin
ARF3 ADP-ribosylation factor 3
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMC1 armadillo repeat containing 1
ATAD2 ATPase family, AAA domain containing 2
ATAD3A ATPase family, AAA domain containing 3A
BOP1 block of proliferation 1
BPHL biphenyl hydrolase-like (serine hydrolase)
C2CD4C C2 calcium-dependent domain containing 4C
C3ORF52 chromosome 3 open reading frame 52
C8ORF33 chromosome 8 open reading frame 33
CAB39 calcium binding protein 39
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CACUL1 CDK2-associated, cullin domain 1
CALR calreticulin
CANX calnexin
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CCDC18 coiled-coil domain containing 18
CCDC68 coiled-coil domain containing 68
CCNB1 cyclin B1
CD44 CD44 molecule (Indian blood group)
CDC20 cell division cycle 20
CDC23 cell division cycle 23
CDCA5 cell division cycle associated 5
CDCA8 cell division cycle associated 8
CDK2 cyclin-dependent kinase 2
CENPBD1 CENPB DNA-binding domains containing 1
CENPI centromere protein I
CENPN centromere protein N
CEP85 centrosomal protein 85kDa
CHD7 chromodomain helicase DNA binding protein 7
CHMP1A charged multivesicular body protein 1A
CHRAC1 chromatin accessibility complex 1
CLIC4 chloride intracellular channel 4
CLSPN claspin
COL28A1 collagen, type XXVIII, alpha 1
COL4A6 collagen, type IV, alpha 6
CORO1C coronin, actin binding protein, 1C
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CRYZ crystallin, zeta (quinone reductase)
CSPG4 chondroitin sulfate proteoglycan 4
CSPP1 centrosome and spindle pole associated protein 1
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CTPS1 CTP synthase 1
CTTN cortactin
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae)
CXORF56 chromosome X open reading frame 56
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DCBLD2 discoidin, CUB and LCCL domain containing 2
DCLK3 doublecortin-like kinase 3
DCLRE1B DNA cross-link repair 1B
DCTN1 dynactin 1
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DFNA5 deafness, autosomal dominant 5
DIAPH1 diaphanous-related formin 1
DIAPH3 diaphanous-related formin 3
DISP2 dispatched homolog 2 (Drosophila)
DKFZP586I1420 uncharacterized protein DKFZp586I1420
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNAAF5 dynein, axonemal, assembly factor 5
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
DPH2 DPH2 homolog (S. cerevisiae)
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
DSCAM Down syndrome cell adhesion molecule
DSE dermatan sulfate epimerase
DUSP6 dual specificity phosphatase 6
E2F3 E2F transcription factor 3
EBNA1BP2 EBNA1 binding protein 2
EFNB1 ephrin-B1
EFNB2 ephrin-B2
EFTUD2 elongation factor Tu GTP binding domain containing 2
EHD4 EH-domain containing 4
EIF5A2 eukaryotic translation initiation factor 5A2
ELF4 E74-like factor 4 (ets domain transcription factor)
ELL elongation factor RNA polymerase II
EMC1 ER membrane protein complex subunit 1
EMC8 ER membrane protein complex subunit 8
ENO1 enolase 1, (alpha)
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERCC8 excision repair cross-complementation group 8
ERRFI1 ERBB receptor feedback inhibitor 1
ESYT1 extended synaptotagmin-like protein 1
EXOSC10 exosome component 10
EXT1 exostosin glycosyltransferase 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FADD Fas (TNFRSF6)-associated via death domain
FAF2 Fas associated factor family member 2
FAM126A family with sequence similarity 126, member A
FAM183B acyloxyacyl hydrolase (neutrophil)
FAM49B family with sequence similarity 49, member B
FAM76A family with sequence similarity 76, member A
FAM91A1 family with sequence similarity 91, member A1
FANCA Fanconi anemia, complementation group A
FANCI Fanconi anemia, complementation group I
FIGN fidgetin
FKBP9 FK506 binding protein 9, 63 kDa
FOSL1 FOS-like antigen 1
FOXC2 forkhead box C2
FRYL FRY-like
FSCN1 fascin actin-bundling protein 1
FST follistatin
FUBP1 far upstream element (FUSE) binding protein 1
GAP43 growth associated protein 43
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GCSH glycine cleavage system protein H (aminomethyl carrier)
GEM GTP binding protein overexpressed in skeletal muscle
GEMIN5 gem (nuclear organelle) associated protein 5
GFOD1 glucose-fructose oxidoreductase domain containing 1
GJB3 gap junction protein, beta 3, 31kDa
GLUD2 glutamate dehydrogenase 2
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNG5 guanine nucleotide binding protein (G protein), gamma 5
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GPBP1 GC-rich promoter binding protein 1
GPR61 G protein-coupled receptor 61
GPRIN1 G protein regulated inducer of neurite outgrowth 1
GSK3B glycogen synthase kinase 3 beta
GTPBP4 GTP binding protein 4
H2AFV H2A histone family, member V
HACD1 3-hydroxyacyl-CoA dehydratase 1
HDAC3 histone deacetylase 3
HMGXB3 HMG box domain containing 3
HMMR hyaluronan-mediated motility receptor (RHAMM)
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HNRNPK heterogeneous nuclear ribonucleoprotein K
HRH1 histamine receptor H1
HSF1 heat shock transcription factor 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IARS isoleucyl-tRNA synthetase
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
IGHMBP2 immunoglobulin mu binding protein 2
IK IK cytokine, down-regulator of HLA II
IL6R interleukin 6 receptor
INHBA inhibin, beta A
INIP INTS3 and NABP interacting protein
INTS1 integrator complex subunit 1
IRS1 insulin receptor substrate 1
ITGA6 integrin, alpha 6
JUN jun proto-oncogene
KBTBD2 kelch repeat and BTB (POZ) domain containing 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KIAA1429 KIAA1429
KIAA1644 KIAA1644
KIF2C kinesin family member 2C
KIF4A kinesin family member 4A
KIF4B kinesin family member 4B
KLF10 Kruppel-like factor 10
KLF6 Kruppel-like factor 6
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL21 kelch-like family member 21
KLHL36 kelch-like family member 36
KPNA6 karyopherin alpha 6 (importin alpha 7)
L1CAM L1 cell adhesion molecule
LASP1 LIM and SH3 protein 1
LHX1 LIM homeobox 1
LINC00304 long intergenic non-protein coding RNA 304
LMNB1 lamin B1
LOC100134868 uncharacterized LOC100134868
LOC401010 nucleolar complex associated 2 homolog (S. cerevisiae) pseudogene
LOC644936 actin, beta pseudogene
LPAR3 lysophosphatidic acid receptor 3
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRRC3 leucine rich repeat containing 3
LRRC42 leucine rich repeat containing 42
LRRC59 leucine rich repeat containing 59
LRRC8C leucine rich repeat containing 8 family, member C
LUZP1 leucine zipper protein 1
LYPLA2P1 lysophospholipase II pseudogene 1
MAMLD1 mastermind-like domain containing 1
MAP7D3 MAP7 domain containing 3
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MCM4 minichromosome maintenance complex component 4
MESDC1 mesoderm development candidate 1
MET MET proto-oncogene, receptor tyrosine kinase
MEX3C mex-3 RNA binding family member C
MFN2 mitofusin 2
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MICALCL MICAL C-terminal like
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MPHOSPH6 M-phase phosphoprotein 6
MROH6 maestro heat-like repeat family member 6
MRPL21 mitochondrial ribosomal protein L21
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MSC musculin
MT1IP metallothionein 1I, pseudogene
MTF2 metal response element binding transcription factor 2
MTFR1 mitochondrial fission regulator 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYADM myeloid-associated differentiation marker
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYO1B myosin IB
NCAPG2 non-SMC condensin II complex, subunit G2
NDC1 NDC1 transmembrane nucleoporin
NECAP2 NECAP endocytosis associated 2
NET1 neuroepithelial cell transforming 1
NIPAL2 NIPA-like domain containing 2
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NOL9 nucleolar protein 9
NOLC1 nucleolar and coiled-body phosphoprotein 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRIP1 nuclear receptor interacting protein 1
NUDCD1 NudC domain containing 1
NUP153 nucleoporin 153kDa
NUP188 nucleoporin 188kDa
NUP205 nucleoporin 205kDa
NUP62CL nucleoporin 62kDa C-terminal like
NUP93 nucleoporin 93kDa
ODF2 outer dense fiber of sperm tails 2
OR2B2 olfactory receptor, family 2, subfamily B, member 2
OR4K13 olfactory receptor, family 4, subfamily K, member 13
OR5A1 olfactory receptor, family 5, subfamily A, member 1
OR5F1 olfactory receptor, family 5, subfamily F, member 1
OR7G2 olfactory receptor, family 7, subfamily G, member 2
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PALM2-AKAP2 PALM2-AKAP2 readthrough
PCDHGA10 protocadherin gamma subfamily A, 10
PDIA3 protein disulfide isomerase family A, member 3
PDIA3P1 protein disulfide isomerase family A, member 3 pseudogene 1
PDIA4 protein disulfide isomerase family A, member 4
PDIA6 protein disulfide isomerase family A, member 6
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGM3 phosphoglucomutase 3
PHF19 PHD finger protein 19
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PHLDB2 pleckstrin homology-like domain, family B, member 2
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLEC plectin
PLK3 polo-like kinase 3
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP4R1L protein phosphatase 4, regulatory subunit 1-like (pseudogene)
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRC1 protein regulator of cytokinesis 1
PRKCA protein kinase C, alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRR11 proline rich 11
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSRC1 proline/serine-rich coiled-coil 1
PTBP3 polypyrimidine tract binding protein 3
PTK7 protein tyrosine kinase 7 (inactive)
PTPDC1 protein tyrosine phosphatase domain containing 1
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PURB purine-rich element binding protein B
PXDC1 PX domain containing 1
PXN paxillin
RAD21L1 RAD21-like 1 (S. pombe)
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RARS arginyl-tRNA synthetase
RBM25 RNA binding motif protein 25
RBM28 RNA binding motif protein 28
RC3H2 ring finger and CCCH-type domains 2
RCAN3 RCAN family member 3
RCC1 regulator of chromosome condensation 1
RCE1 Ras converting CAAX endopeptidase 1
RDH8 retinol dehydrogenase 8 (all-trans)
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RGS20 regulator of G-protein signaling 20
RHOB ras homolog family member B
RNF121 ring finger protein 121
RPL7 ribosomal protein L7
RPN1 ribophorin I
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPSAP52 ribosomal protein SA pseudogene 52
RRM2 ribonucleotide reductase M2
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SALL3 spalt-like transcription factor 3
SARS seryl-tRNA synthetase
SCRN1 secernin 1
SDC4 syndecan 4
SEC24A SEC24 family member A
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SEPT7 septin 7
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SF3A3 splicing factor 3a, subunit 3, 60kDa
SFPQ splicing factor proline/glutamine-rich
SGMS2 sphingomyelin synthase 2
SIRPB1 signal-regulatory protein beta 1
SLAIN2 SLAIN motif family, member 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SLC30A7 solute carrier family 30 (zinc transporter), member 7
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC38A2 solute carrier family 38, member 2
SLC38A9 solute carrier family 38, member 9
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLC7A5P2 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5)
SNX30 sorting nexin family member 30
SRFBP1 serum response factor binding protein 1
SSR1 signal sequence receptor, alpha
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
STK10 serine/threonine kinase 10
STK17B serine/threonine kinase 17b
STRIP1 striatin interacting protein 1
SURF4 surfeit 4
SZRD1 SUZ RNA binding domain containing 1
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
TARDBP TAR DNA binding protein
TBRG4 transforming growth factor beta regulator 4
TCAF1 TRPM8 channel-associated factor 1
TCERG1 transcription elongation regulator 1
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TCOF1 Treacher Collins-Franceschetti syndrome 1
THBS1 thrombospondin 1
THEG theg spermatid protein
TLDC1 TBC/LysM-associated domain containing 1
TMCC3 transmembrane and coiled-coil domain family 3
TMED5 transmembrane emp24 protein transport domain containing 5
TMED9 transmembrane emp24 protein transport domain containing 9
TMEM2 transmembrane protein 2
TMEM67 transmembrane protein 67
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TOR1B torsin family 1, member B (torsin B)
TPCN2 two pore segment channel 2
TPD52L2 tumor protein D52-like 2
TRAM2 translocation associated membrane protein 2
TRIB1 tribbles pseudokinase 1
TRIM36 tripartite motif containing 36
TSC22D2 TSC22 domain family, member 2
TTC37 tetratricopeptide repeat domain 37
TTC4 tetratricopeptide repeat domain 4
TUBA1B tubulin, alpha 1b
TUBB3 tubulin, beta 3 class III
TUBG1 tubulin, gamma 1
TXNDC2 thioredoxin domain containing 2 (spermatozoa)
UBE2C ubiquitin-conjugating enzyme E2C
UBR5 ubiquitin protein ligase E3 component n-recognin 5
ULBP3 UL16 binding protein 3
USP10 ubiquitin specific peptidase 10
UTP15 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
VAMP3 vesicle-associated membrane protein 3
VAV2 vav 2 guanine nucleotide exchange factor
VN1R10P vomeronasal 1 receptor 10 pseudogene
WDR36 WD repeat domain 36
WDR4 WD repeat domain 4
WDR55 WD repeat domain 55
WRNIP1 Werner helicase interacting protein 1
XKR9 XK, Kell blood group complex subunit-related family, member 9
YARS tyrosyl-tRNA synthetase
YIPF5 Yip1 domain family, member 5
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZC3H18 zinc finger CCCH-type containing 18
ZCCHC14 zinc finger, CCHC domain containing 14
ZFPM1 zinc finger protein, FOG family member 1
ZMAT2 zinc finger, matrin-type 2
ZNF229 zinc finger protein 229
ZNF487 zinc finger protein 487
ZNF778 zinc finger protein 778
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase
ZRANB3 zinc finger, RAN-binding domain containing 3

low expression

Symbol Name
C2ORF42 chromosome 2 open reading frame 42