Head and Neck Neoplasms Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651) (Experimental Factor Ontology, EFO_0004284)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D006258
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Genes

494 genes/proteins associated with the disease Head and Neck Neoplasms from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
MAPK1 mitogen-activated protein kinase 1 2.88009
MAL mal, T-cell differentiation protein 2.88009
BCL2L1 BCL2-like 1 2.88009
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 2.88009
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 2.88009
TYMS thymidylate synthetase 2.88009
TGFA transforming growth factor, alpha 2.88009
BCL2 B-cell CLL/lymphoma 2 2.88009
GRP gastrin-releasing peptide 2.88009
MAPK3 mitogen-activated protein kinase 3 2.88009
GPX1 glutathione peroxidase 1 2.88009
VEGFA vascular endothelial growth factor A 2.88009
EGFR epidermal growth factor receptor 2.88009
CSF3 colony stimulating factor 3 (granulocyte) 2.88009
DPYD dihydropyrimidine dehydrogenase 2.88009
AREG amphiregulin 2.88009
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 2.88009
RAD51 RAD51 recombinase 2.88009
PRAME preferentially expressed antigen in melanoma 2.88009
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 2.88009
UROD uroporphyrinogen decarboxylase 2.88009
FAT1 FAT atypical cadherin 1 2.88009
RARB retinoic acid receptor, beta 2.88009
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 2.09309
BAX BCL2-associated X protein 2.02061
H2AFX H2A histone family, member X 2.00261
TP53 tumor protein p53 1.9821
BIRC2 baculoviral IAP repeat containing 2 1.96402
BIRC5 baculoviral IAP repeat containing 5 1.96147
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.90042
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.89536
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.89169
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.8826
RB1 retinoblastoma 1 1.86288
E2F1 E2F transcription factor 1 1.85344
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.8487
CDK1 cyclin-dependent kinase 1 1.84658
TERT telomerase reverse transcriptase 1.80472
CCNB1 cyclin B1 1.79618
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.79159
PARP1 poly (ADP-ribose) polymerase 1 1.78397
MMP1 matrix metallopeptidase 1 1.78283
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.77511
PCNA proliferating cell nuclear antigen 1.77413
FASLG Fas ligand (TNF superfamily, member 6) 1.76481
FAS Fas cell surface death receptor 1.76405
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.756
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.74842
IL6 interleukin 6 1.74361
DDIT3 DNA-damage-inducible transcript 3 1.73698
GADD45A growth arrest and DNA-damage-inducible, alpha 1.73129
CXCL8 chemokine (C-X-C motif) ligand 8 1.7224
EPO erythropoietin 1.72014
SOD2 superoxide dismutase 2, mitochondrial 1.71687
CDK2 cyclin-dependent kinase 2 1.70865
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.7014
CYCS cytochrome c, somatic 1.69909
MKI67 marker of proliferation Ki-67 1.69784
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.69659
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.68612
F3 coagulation factor III (thromboplastin, tissue factor) 1.67547
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.67333
ERBB2 erb-b2 receptor tyrosine kinase 2 1.67202
TYMP thymidine phosphorylase 1.65292
JUN jun proto-oncogene 1.65091
CCND1 cyclin D1 1.64573
MAPK8 mitogen-activated protein kinase 8 1.62176
BIRC3 baculoviral IAP repeat containing 3 1.61897
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.60337
MAP2K1 mitogen-activated protein kinase kinase 1 1.60291
CTGF connective tissue growth factor 1.59731
EGR1 early growth response 1 1.59685
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.59614
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.58983
BRCA1 breast cancer 1, early onset 1.58678
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.58421
MPO myeloperoxidase 1.57618
MCL1 myeloid cell leukemia 1 1.5745
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.56484
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.56312
ATM ATM serine/threonine kinase 1.55921
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.55747
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.55574
CD44 CD44 molecule (Indian blood group) 1.55402
HSPB1 heat shock 27kDa protein 1 1.55108
MMP3 matrix metallopeptidase 3 1.54912
COL1A2 collagen, type I, alpha 2 1.54281
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.54111
MMP9 matrix metallopeptidase 9 1.53844
PRKCD protein kinase C, delta 1.5382
BID BH3 interacting domain death agonist 1.53772
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 1.53431
COL1A1 collagen, type I, alpha 1 1.53431
PLAU plasminogen activator, urokinase 1.53357
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 1.5311
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 1.52816
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.52338
TGFB1 transforming growth factor, beta 1 1.5186
MAPK14 mitogen-activated protein kinase 14 1.5143
CAT catalase 1.50776
THBS1 thrombospondin 1 1.50599
BBC3 BCL2 binding component 3 1.50599
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.49839
TP53I3 tumor protein p53 inducible protein 3 1.49736
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.49457
CFLAR CASP8 and FADD-like apoptosis regulator 1.49071
IL10 interleukin 10 1.48916
TOP2A topoisomerase (DNA) II alpha 170kDa 1.48659
G6PD glucose-6-phosphate dehydrogenase 1.48531
TNF tumor necrosis factor 1.47608
BAK1 BCL2-antagonist/killer 1 1.47452
HRAS Harvey rat sarcoma viral oncogene homolog 1.47193
DIABLO diablo, IAP-binding mitochondrial protein 1.46595
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.46383
NOS3 nitric oxide synthase 3 (endothelial cell) 1.45803
MMP2 matrix metallopeptidase 2 1.45643
ERCC1 excision repair cross-complementation group 1 1.45643
BTG2 BTG family, member 2 1.45352
MGMT O-6-methylguanine-DNA methyltransferase 1.45352
S100P S100 calcium binding protein P 1.45141
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.44872
TFPI2 tissue factor pathway inhibitor 2 1.4479
IGF1R insulin-like growth factor 1 receptor 1.44166
CCNE1 cyclin E1 1.43727
EGF epidermal growth factor 1.42994
CCNA2 cyclin A2 1.4275
BMP4 bone morphogenetic protein 4 1.42401
VCAN versican 1.42074
IL1B interleukin 1, beta 1.41532
ATF3 activating transcription factor 3 1.41119
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.41063
PPARD peroxisome proliferator-activated receptor delta 1.40925
CCL2 chemokine (C-C motif) ligand 2 1.4087
PRC1 protein regulator of cytokinesis 1 1.40513
CSE1L CSE1 chromosome segregation 1-like (yeast) 1.40064
PKP2 plakophilin 2 1.40064
EPCAM epithelial cell adhesion molecule 1.3931
RARA retinoic acid receptor, alpha 1.38696
CDKN2A cyclin-dependent kinase inhibitor 2A 1.38384
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 1.38156
GDF15 growth differentiation factor 15 1.37532
GSK3B glycogen synthase kinase 3 beta 1.37446
BAD BCL2-associated agonist of cell death 1.37389
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.3736
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 1.37332
MOK MOK protein kinase 1.37189
TLR4 toll-like receptor 4 1.37132
BCL2A1 BCL2-related protein A1 1.37047
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.37047
RRM2 ribonucleotide reductase M2 1.36961
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.36961
VIM vimentin 1.36591
FGF2 fibroblast growth factor 2 (basic) 1.36447
COL4A2 collagen, type IV, alpha 2 1.36418
TRIM2 tripartite motif containing 2 1.35991
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.35792
TP73 tumor protein p73 1.35589
FANCD2 Fanconi anemia, complementation group D2 1.35155
SGK1 serum/glucocorticoid regulated kinase 1 1.34606
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 1.34372
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.34372
HMOX1 heme oxygenase 1 1.34314
CXCR4 chemokine (C-X-C motif) receptor 4 1.34256
UNG uracil-DNA glycosylase 1.34169
NQO1 NAD(P)H dehydrogenase, quinone 1 1.34169
CCNG2 cyclin G2 1.34169
CCND2 cyclin D2 1.34111
CDK4 cyclin-dependent kinase 4 1.33966
CTSB cathepsin B 1.33583
CHEK1 checkpoint kinase 1 1.33405
TRAF2 TNF receptor-associated factor 2 1.33199
BECN1 beclin 1, autophagy related 1.32964
VCAM1 vascular cell adhesion molecule 1 1.32905
CAV1 caveolin 1, caveolae protein, 22kDa 1.32726
FOXO1 forkhead box O1 1.32696
FOS FBJ murine osteosarcoma viral oncogene homolog 1.32607
CD14 CD14 molecule 1.32577
CDC6 cell division cycle 6 1.32458
SNAI2 snail family zinc finger 2 1.32074
UBE2C ubiquitin-conjugating enzyme E2C 1.31776
MSMO1 methylsterol monooxygenase 1 1.31776
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.31596
CP ceruloplasmin (ferroxidase) 1.30788
DUSP10 dual specificity phosphatase 10 1.30635
PTTG1 pituitary tumor-transforming 1 1.30635
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.30635
KDM4B lysine (K)-specific demethylase 4B 1.30299
F2 coagulation factor II (thrombin) 1.29996
RFC3 replication factor C (activator 1) 3, 38kDa 1.29936
CASP12 caspase 12 (gene/pseudogene) 1.29936
FN1 fibronectin 1 1.29936
SRI sorcin 1.29688
IGFBP5 insulin-like growth factor binding protein 5 1.28641
GADD45G growth arrest and DNA-damage-inducible, gamma 1.28641
ICAM1 intercellular adhesion molecule 1 1.28549
EDN1 endothelin 1 1.28487
S100A9 S100 calcium binding protein A9 1.28425
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.28425
MAGEA6 melanoma antigen family A6 1.28272
ITGAV integrin, alpha V 1.27966
PTX3 pentraxin 3, long 1.27316
MCM7 minichromosome maintenance complex component 7 1.27009
CD40LG CD40 ligand 1.27009
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.26978
NGF nerve growth factor (beta polypeptide) 1.26856
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.26576
HSPA8 heat shock 70kDa protein 8 1.26421
S100A8 S100 calcium binding protein A8 1.2639
TIMP3 TIMP metallopeptidase inhibitor 3 1.2639
MSH6 mutS homolog 6 1.25807
IFNG interferon, gamma 1.25619
IL18 interleukin 18 1.25588
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.25588
PRKDC protein kinase, DNA-activated, catalytic polypeptide 1.25525
ABLIM1 actin binding LIM protein 1 1.25369
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.25307
CCNG1 cyclin G1 1.24843
BCL2L12 BCL2-like 12 (proline rich) 1.24687
S100A10 S100 calcium binding protein A10 1.24655
SMAD7 SMAD family member 7 1.24655
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.24655
KEAP1 kelch-like ECH-associated protein 1 1.24655
LMNB1 lamin B1 1.24655
MAP2K2 mitogen-activated protein kinase kinase 2 1.24655
L1CAM L1 cell adhesion molecule 1.24401
STC2 stanniocalcin 2 1.24087
NANOG Nanog homeobox 1.2393
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.23899
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.23806
MME membrane metallo-endopeptidase 1.23806
CCNB2 cyclin B2 1.23743
CCND3 cyclin D3 1.23743
ERBB3 erb-b2 receptor tyrosine kinase 3 1.23552
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 1.23488
IL17RB interleukin 17 receptor B 1.23488
EP300 E1A binding protein p300 1.23265
CDC25A cell division cycle 25A 1.23265
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.23201
IL1RN interleukin 1 receptor antagonist 1.23011
CHEK2 checkpoint kinase 2 1.23011
EDNRB endothelin receptor type B 1.23011
FAM171A1 family with sequence similarity 171, member A1 1.22821
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.22727
CKS2 CDC28 protein kinase regulatory subunit 2 1.22727
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.22339
NUSAP1 nucleolar and spindle associated protein 1 1.22209
E2F3 E2F transcription factor 3 1.22145
FANCI Fanconi anemia, complementation group I 1.22145
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 1.21951
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.21695
ALOX12 arachidonate 12-lipoxygenase 1.21695
CXCL10 chemokine (C-X-C motif) ligand 10 1.21173
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.20913
AGR2 anterior gradient 2 1.20848
DDB2 damage-specific DNA binding protein 2, 48kDa 1.20848
SP1 Sp1 transcription factor 1.20558
SRGN serglycin 1.20427
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.20229
PLK1 polo-like kinase 1 1.20163
CDKN3 cyclin-dependent kinase inhibitor 3 1.20163
MAPK9 mitogen-activated protein kinase 9 1.20064
RAD51C RAD51 paralog C 1.19999
BLM Bloom syndrome, RecQ helicase-like 1.19607
SLCO2A1 solute carrier organic anion transporter family, member 2A1 1.19607
GCLC glutamate-cysteine ligase, catalytic subunit 1.19509
OSBPL10 oxysterol binding protein-like 10 1.19509
S100A4 S100 calcium binding protein A4 1.19412
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.19246
RAMP1 receptor (G protein-coupled) activity modifying protein 1 1.19213
HDAC1 histone deacetylase 1 1.19179
GSTP1 glutathione S-transferase pi 1 1.18981
GSN gelsolin 1.18948
TPD52L1 tumor protein D52-like 1 1.18816
TMSB4X thymosin beta 4, X-linked 1.18816
G0S2 G0/G1 switch 2 1.18718
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.18489
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.18424
IL1A interleukin 1, alpha 1.18359
IL12B interleukin 12B 1.18193
MELK maternal embryonic leucine zipper kinase 1.18059
NR1H3 nuclear receptor subfamily 1, group H, member 3 1.17993
IL2 interleukin 2 1.17993
BTG3 BTG family, member 3 1.17695
AURKA aurora kinase A 1.17333
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.17168
HSPE1 heat shock 10kDa protein 1 1.17101
MBP myelin basic protein 1.16666
KIFAP3 kinesin-associated protein 3 1.166
IGF1 insulin-like growth factor 1 (somatomedin C) 1.166
HMGB1 high mobility group box 1 1.16434
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.16302
NCOA3 nuclear receptor coactivator 3 1.16236
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.16236
IGFBP3 insulin-like growth factor binding protein 3 1.16137
KLK3 kallikrein-related peptidase 3 1.16001
FKBP5 FK506 binding protein 5 1.16001
BUB3 BUB3 mitotic checkpoint protein 1.15967
LPAR1 lysophosphatidic acid receptor 1 1.15899
CTSL cathepsin L 1.15797
PSAP prosaposin 1.1556
DHFR dihydrofolate reductase 1.15156
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.14989
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.14816
KLF6 Kruppel-like factor 6 1.14747
NAIP NLR family, apoptosis inhibitory protein 1.14678
CXCL14 chemokine (C-X-C motif) ligand 14 1.14541
PRNP prion protein 1.14541
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.14438
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.14404
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 1.142
KLK6 kallikrein-related peptidase 6 1.1403
CDCA8 cell division cycle associated 8 1.13895
BIRC7 baculoviral IAP repeat containing 7 1.13758
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.13724
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.13724
PPARG peroxisome proliferator-activated receptor gamma 1.13689
LIG1 ligase I, DNA, ATP-dependent 1.13552
BORA bora, aurora kinase A activator 1.13449
PDGFB platelet-derived growth factor beta polypeptide 1.13313
JUNB jun B proto-oncogene 1.13279
FHL1 four and a half LIM domains 1 1.1294
FHL2 four and a half LIM domains 2 1.12906
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.12906
PTEN phosphatase and tensin homolog 1.12872
CDC25C cell division cycle 25C 1.12737
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.12323
PNMA2 paraneoplastic Ma antigen 2 1.12254
APAF1 apoptotic peptidase activating factor 1 1.12151
GPX2 glutathione peroxidase 2 1.12151
CDC20 cell division cycle 20 1.12151
POU5F1 POU class 5 homeobox 1 1.12014
AKAP12 A kinase (PRKA) anchor protein 12 1.12014
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.1198
XDH xanthine dehydrogenase 1.11945
PTK2 protein tyrosine kinase 2 1.11945
CLU clusterin 1.11945
DUSP3 dual specificity phosphatase 3 1.11775
LHX2 LIM homeobox 2 1.11775
TRIM28 tripartite motif containing 28 1.11775
DRAM1 DNA-damage regulated autophagy modulator 1 1.11741
SLC31A1 solute carrier family 31 (copper transporter), member 1 1.11707
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 1.11431
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 1.1122
PIR pirin (iron-binding nuclear protein) 1.11116
KIF23 kinesin family member 23 1.11116
KLF2 Kruppel-like factor 2 1.11116
GADD45B growth arrest and DNA-damage-inducible, beta 1.11011
TGM2 transglutaminase 2 1.11011
FBN1 fibrillin 1 1.10838
SELL selectin L 1.10838
FUCA1 fucosidase, alpha-L- 1, tissue 1.10734
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 1.10665
SESN1 sestrin 1 1.10562
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.10388
ANGPTL4 angiopoietin-like 4 1.10282
VWF von Willebrand factor 1.10282
IRS1 insulin receptor substrate 1 1.10282
CYR61 cysteine-rich, angiogenic inducer, 61 1.10282
HMMR hyaluronan-mediated motility receptor (RHAMM) 1.10246
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 1.10246
ODC1 ornithine decarboxylase 1 1.10246
ADAM10 ADAM metallopeptidase domain 10 1.10175
TJP3 tight junction protein 3 1.10175
HIST1H2BD histone cluster 1, H2bd 1.1014
ADAM19 ADAM metallopeptidase domain 19 1.1014
TXNIP thioredoxin interacting protein 1.10104
BMI1 BMI1 proto-oncogene, polycomb ring finger 1.09681
IFI6 interferon, alpha-inducible protein 6 1.09681
ASS1 argininosuccinate synthase 1 1.09401
INSIG1 insulin induced gene 1 1.09226
PECAM1 platelet/endothelial cell adhesion molecule 1 1.09154
PAX8 paired box 8 1.09154
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.09119
HSPA1B heat shock 70kDa protein 1B 1.09047
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.08868
FYN FYN proto-oncogene, Src family tyrosine kinase 1.08868
SOD1 superoxide dismutase 1, soluble 1.08762
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.0869
XAF1 XIAP associated factor 1 1.08655
POR P450 (cytochrome) oxidoreductase 1.08619
CD9 CD9 molecule 1.08584
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.08337
IGFBP4 insulin-like growth factor binding protein 4 1.08337
TMPO thymopoietin 1.08337
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 1.08301
FKBP1B FK506 binding protein 1B, 12.6 kDa 1.08196
PRKCI protein kinase C, iota 1.08161
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.08055
CRYAB crystallin, alpha B 1.08019
ACTA2 actin, alpha 2, smooth muscle, aorta 1.07911
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.0784
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.07804
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 1.07696
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.07553
THBD thrombomodulin 1.07553
TFF1 trefoil factor 1 1.07518
XBP1 X-box binding protein 1 1.07482
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.07482
IL12A interleukin 12A 1.0734
PLAUR plasminogen activator, urokinase receptor 1.0734
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.07305
RRAS related RAS viral (r-ras) oncogene homolog 1.07269
SAT1 spermidine/spermine N1-acetyltransferase 1 1.07269
MYLK myosin light chain kinase 1.07269
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.07022
RBP1 retinol binding protein 1, cellular 1.07022
PSIP1 PC4 and SFRS1 interacting protein 1 1.06808
SNX10 sorting nexin 10 1.06808
DKK3 dickkopf WNT signaling pathway inhibitor 3 1.06808
NKX3-1 NK3 homeobox 1 1.06808
PMP22 peripheral myelin protein 22 1.06771
ERN1 endoplasmic reticulum to nucleus signaling 1 1.06771
MCM4 minichromosome maintenance complex component 4 1.06771
CDC42 cell division cycle 42 1.06771
CSF1 colony stimulating factor 1 (macrophage) 1.06771
VAV3 vav 3 guanine nucleotide exchange factor 1.06771
ESR1 estrogen receptor 1 1.06625
CD38 CD38 molecule 1.06515
MAP2K6 mitogen-activated protein kinase kinase 6 1.06515
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 1.06261
PTGES prostaglandin E synthase 1.06008
PERP PERP, TP53 apoptosis effector 1.05972
FZD1 frizzled class receptor 1 1.05936
FANCG Fanconi anemia, complementation group G 1.05936
STK17B serine/threonine kinase 17b 1.059
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 1.05721
NFE2L2 nuclear factor, erythroid 2-like 2 1.05721
NKAIN1 Na+/K+ transporting ATPase interacting 1 1.0561
SP3 Sp3 transcription factor 1.05498
LGALS8 lectin, galactoside-binding, soluble, 8 1.05498
CD4 CD4 molecule 1.05461
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.05461
METTL7A methyltransferase like 7A 1.05461
KIF20A kinesin family member 20A 1.05274
AKR1C3 aldo-keto reductase family 1, member C3 1.05237
DDIT4L DNA-damage-inducible transcript 4-like 1.05089
PSMC3IP PSMC3 interacting protein 1.05052
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.04794
DBF4 DBF4 zinc finger 1.04647
NOS2 nitric oxide synthase 2, inducible 1.04314
BDNF brain-derived neurotrophic factor 1.04239
DCT dopachrome tautomerase 1.04239
PBX1 pre-B-cell leukemia homeobox 1 1.04201
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.03827
HES1 hes family bHLH transcription factor 1 1.03827
HMGB2 high mobility group box 2 1.03827
KLF4 Kruppel-like factor 4 (gut) 1.03827
KAT2B K(lysine) acetyltransferase 2B 1.03789
RFC5 replication factor C (activator 1) 5, 36.5kDa 1.03789
ALB albumin 1.03752
INS insulin 1.03678
TSC22D3 TSC22 domain family, member 3 1.03604
PLIN2 perilipin 2 1.03604
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 1.03419
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.03382
FSTL1 follistatin-like 1 1.03382
CHAF1A chromatin assembly factor 1, subunit A (p150) 1.03382
HDGFRP3 hepatoma-derived growth factor, related protein 3 1.03084
PALLD palladin, cytoskeletal associated protein 1.03009
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 1.03009
NBN nibrin 1.03009
RAD23B RAD23 homolog B (S. cerevisiae) 1.03009
RBM34 RNA binding motif protein 34 1.02933
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.02933
MAGEA12 melanoma antigen family A12 1.02933
ALOX5 arachidonate 5-lipoxygenase 1.02783
NAMPT nicotinamide phosphoribosyltransferase 1.02708
NRP1 neuropilin 1 1.02708
MCM2 minichromosome maintenance complex component 2 1.02708
LMNA lamin A/C 1.02485
MCM6 minichromosome maintenance complex component 6 1.02485
IL4 interleukin 4 1.0241
HDAC2 histone deacetylase 2 1.02262
GFRA1 GDNF family receptor alpha 1 1.02225
PHYH phytanoyl-CoA 2-hydroxylase 1.02225
EPOR erythropoietin receptor 1.02225
RFC4 replication factor C (activator 1) 4, 37kDa 1.01852
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.01663
INHBA inhibin, beta A 1.01587
KIF15 kinesin family member 15 1.01512
CD24 CD24 molecule 1.01474
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 1.01474
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.01399
SPATA18 spermatogenesis associated 18 1.01286
GRHL3 grainyhead-like 3 (Drosophila) 1.01286
CXCL2 chemokine (C-X-C motif) ligand 2 1.01286
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.01174
CCNE2 cyclin E2 1.01174
TK1 thymidine kinase 1, soluble 1.01174
TAGLN transgelin 1.01174
ATG5 autophagy related 5 1.01174
SOX17 SRY (sex determining region Y)-box 17 1.01137
CTSH cathepsin H 1.01099
IGFBP7 insulin-like growth factor binding protein 7 1.01099