HCC1937 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

325 genes with high or low expression in HCC1937 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
KLK5 kallikrein-related peptidase 5 3.0887
ZNF304 zinc finger protein 304 3.08019
SHARPIN SHANK-associated RH domain interactor 2.98342
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) 2.8968
ZNF134 zinc finger protein 134 2.89384
ZNF623 zinc finger protein 623 2.82193
ZNF544 zinc finger protein 544 2.79299
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 2.78941
SIRT5 sirtuin 5 2.62852
KLK7 kallikrein-related peptidase 7 2.59512
KRT16 keratin 16, type I 2.53038
KLK8 kallikrein-related peptidase 8 2.45227
JRK Jrk homolog (mouse) 2.43703
KRT9 keratin 9, type I 2.4057
RNF31 ring finger protein 31 2.37905
RAB5A RAB5A, member RAS oncogene family 2.35307
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 2.30899
MAP3K13 mitogen-activated protein kinase kinase kinase 13 2.29423
FAM192A family with sequence similarity 192, member A 2.24207
ZNF551 zinc finger protein 551 2.23456
ZNF419 zinc finger protein 419 2.22692
PDCD6 programmed cell death 6 2.195
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 2.17912
CIZ1 CDKN1A interacting zinc finger protein 1 2.17131
TLDC1 TBC/LysM-associated domain containing 1 2.16709
ZNF274 zinc finger protein 274 2.15917
GMPS guanine monphosphate synthase 2.12772
SENP5 SUMO1/sentrin specific peptidase 5 2.12216
IRF9 interferon regulatory factor 9 2.11837
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 2.10112
GAS8 growth arrest-specific 8 2.08631
ZNF264 zinc finger protein 264 2.05033
SCRIB scribbled planar cell polarity protein 2.04516
CHMP1A charged multivesicular body protein 1A 2.02866
LTB4R leukotriene B4 receptor 2.00963
LRRC14 leucine rich repeat containing 14 1.99184
ZNF16 zinc finger protein 16 1.98641
PNPLA4 patatin-like phospholipase domain containing 4 1.93875
ZNF7 zinc finger protein 7 1.93109
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 1.92894
ZNF137P zinc finger protein 137, pseudogene 1.92397
GIPC1 GIPC PDZ domain containing family, member 1 1.9178
ZNF688 zinc finger protein 688 1.90263
ZNF211 zinc finger protein 211 1.89888
OPA1 optic atrophy 1 (autosomal dominant) 1.89463
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 1.88839
ACE2 angiotensin I converting enzyme 2 1.88265
FAM175B family with sequence similarity 175, member B 1.88138
ADAT1 adenosine deaminase, tRNA-specific 1 1.85721
ADGRL1 adhesion G protein-coupled receptor L1 1.85616
ZNF34 zinc finger protein 34 1.85225
AOC2 amine oxidase, copper containing 2 (retina-specific) 1.84295
MYH14 myosin, heavy chain 14, non-muscle 1.83864
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 1.82992
PYCRL pyrroline-5-carboxylate reductase-like 1.82916
LY6E lymphocyte antigen 6 complex, locus E 1.82454
UFL1 UFM1-specific ligase 1 1.82216
OASL 2'-5'-oligoadenylate synthetase-like 1.80737
PTK2 protein tyrosine kinase 2 1.78965
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 1.7845
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 1.77939
COQ4 coenzyme Q4 1.76067
OFD1 oral-facial-digital syndrome 1 1.76058
BCL2L2 BCL2-like 2 1.75269
ANPEP alanyl (membrane) aminopeptidase 1.74996
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 1.74885
ALPPL2 alkaline phosphatase, placental-like 2 1.74415
CTAGE5 CTAGE family, member 5 1.73529
NSUN7 NOP2/Sun domain family, member 7 1.73064
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) 1.72922
ZNF606 zinc finger protein 606 1.72736
GOSR1 golgi SNAP receptor complex member 1 1.72575
PI3 peptidase inhibitor 3, skin-derived 1.72321
MUC16 mucin 16, cell surface associated 1.72088
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 1.72065
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 1.71985
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 1.70872
ZNF331 zinc finger protein 331 1.70518
PAQR6 progestin and adipoQ receptor family member VI 1.70443
NEK2 NIMA-related kinase 2 1.70291
RAD23A RAD23 homolog A (S. cerevisiae) 1.7017
RTP4 receptor (chemosensory) transporter protein 4 1.69608
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 1.69145
MGMT O-6-methylguanine-DNA methyltransferase 1.67782
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 1.67752
RBM12B RNA binding motif protein 12B 1.67664
ZC3H3 zinc finger CCCH-type containing 3 1.67309
ZSCAN5A zinc finger and SCAN domain containing 5A 1.67219
ZNF629 zinc finger protein 629 1.66963
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 1.66672
POU2F3 POU class 2 homeobox 3 1.66449
WIZ widely interspaced zinc finger motifs 1.65947
PLVAP plasmalemma vesicle associated protein 1.65535
DVL3 dishevelled segment polarity protein 3 1.64818
TBCCD1 TBCC domain containing 1 1.64493
DHRS1 dehydrogenase/reductase (SDR family) member 1 1.63568
CRABP2 cellular retinoic acid binding protein 2 1.62903
KRT10 keratin 10, type I 1.6284
GFOD1 glucose-fructose oxidoreductase domain containing 1 1.62735
ATP13A3 ATPase type 13A3 1.62305
CSNK1A1 casein kinase 1, alpha 1 1.61899
CYC1 cytochrome c-1 1.61571
PITX1 paired-like homeodomain 1 1.61458
ALPP alkaline phosphatase, placental 1.61418
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.6114
MLF2 myeloid leukemia factor 2 1.60167
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 1.59365
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 1.58958
ARF6 ADP-ribosylation factor 6 1.58361
RNF114 ring finger protein 114 1.57844
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 1.57622
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 1.57297
ZNF768 zinc finger protein 768 1.57169
NANS N-acetylneuraminic acid synthase 1.56993
PAPD7 PAP associated domain containing 7 1.56756
FBP1 fructose-1,6-bisphosphatase 1 1.55984
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 1.55876
NOD2 nucleotide-binding oligomerization domain containing 2 1.55628
KLK10 kallikrein-related peptidase 10 1.55298
TMPRSS3 transmembrane protease, serine 3 1.55171
SLC39A4 solute carrier family 39 (zinc transporter), member 4 1.54968
TRIM17 tripartite motif containing 17 1.54928
CHMP4A charged multivesicular body protein 4A 1.54914
KIAA0485 uncharacterized LOC57235 1.5475
RAP2B RAP2B, member of RAS oncogene family 1.5419
IER2 immediate early response 2 1.54055
CYHR1 cysteine/histidine-rich 1 1.53957
BAG5 BCL2-associated athanogene 5 1.53703
N4BP1 NEDD4 binding protein 1 1.53226
INVS inversin 1.52956
COG4 component of oligomeric golgi complex 4 1.52545
NUBPL nucleotide binding protein-like 1.5241
CTBP2 C-terminal binding protein 2 1.52115
TGM1 transglutaminase 1 1.52097
UBXN7 UBX domain protein 7 1.5209
TDRD12 tudor domain containing 12 1.51743
VGLL1 vestigial-like family member 1 1.51647
PRPF31 pre-mRNA processing factor 31 1.51529
FOXJ2 forkhead box J2 1.50498
EMC8 ER membrane protein complex subunit 8 1.49986
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.49228
PPP4C protein phosphatase 4, catalytic subunit 1.49189
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 1.48695
UBE3C ubiquitin protein ligase E3C 1.48342
DMC1 DNA meiotic recombinase 1 1.46782
KLHL3 kelch-like family member 3 1.46555
CALML5 calmodulin-like 5 1.46514
ZNF324B zinc finger protein 324B 1.46472
KLK6 kallikrein-related peptidase 6 1.46422
AKAP3 A kinase (PRKA) anchor protein 3 1.46238
TMEM39A transmembrane protein 39A 1.44936
CHD9 chromodomain helicase DNA binding protein 9 1.44771
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 1.4462
NUSAP1 nucleolar and spindle associated protein 1 1.44584
PTGIS prostaglandin I2 (prostacyclin) synthase 1.44546
HES1 hes family bHLH transcription factor 1 1.44349
IMPACT impact RWD domain protein 1.44235
PLSCR1 phospholipid scramblase 1 1.44223
LXN latexin 1.43783
EPS8L1 EPS8-like 1 1.43615
PHF2 PHD finger protein 2 1.43395
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 1.428
ZNF8 zinc finger protein 8 1.42732
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 1.4243
AP3S2 adaptor-related protein complex 3, sigma 2 subunit 1.42361
STX16 syntaxin 16 1.41785

low expression

Symbol Name Standardized Value
GLUD1 glutamate dehydrogenase 1 -3.53725
FAM35A family with sequence similarity 35, member A -3.53725
GSTP1 glutathione S-transferase pi 1 -3.49548
GRIP2 glutamate receptor interacting protein 2 -2.89657
RPL17 ribosomal protein L17 -2.80196
MINPP1 multiple inositol-polyphosphate phosphatase 1 -2.72483
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 -2.55218
PWP2 PWP2 periodic tryptophan protein homolog (yeast) -2.51413
NCL nucleolin -2.50859
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle -2.43794
DSCR3 Down syndrome critical region 3 -2.40455
GLUD2 glutamate dehydrogenase 2 -2.36112
DAPK3 death-associated protein kinase 3 -2.34541
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.31165
TXNL4A thioredoxin-like 4A -2.30918
SYT11 synaptotagmin XI -2.26446
TM2D3 TM2 domain containing 3 -2.26023
STRN striatin, calmodulin binding protein -2.23576
TSNAXIP1 translin-associated factor X interacting protein 1 -2.23095
IPO7 importin 7 -2.22653
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 -2.22018
USP32 ubiquitin specific peptidase 32 -2.21704
CTR9 CTR9, Paf1/RNA polymerase II complex component -2.21143
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 -2.19008
CXXC1 CXXC finger protein 1 -2.1821
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) -2.17718
KPNA3 karyopherin alpha 3 (importin alpha 4) -2.16996
BCAP29 B-cell receptor-associated protein 29 -2.16458
ARAF A-Raf proto-oncogene, serine/threonine kinase -2.15704
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -2.15581
CERS2 ceramide synthase 2 -2.14369
RPS3 ribosomal protein S3 -2.14135
CISD1 CDGSH iron sulfur domain 1 -2.13628
ZBED4 zinc finger, BED-type containing 4 -2.13422
METAP1 methionyl aminopeptidase 1 -2.12206
SCAMP3 secretory carrier membrane protein 3 -2.11682
SEC23IP SEC23 interacting protein -2.10753
STK25 serine/threonine kinase 25 -2.10339
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -2.10279
LYRM4 LYR motif containing 4 -2.09464
OR7E24 olfactory receptor, family 7, subfamily E, member 24 -2.08532
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) -2.07553
PPIA peptidylprolyl isomerase A (cyclophilin A) -2.07427
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -2.06447
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 -2.05435
LINS lines homolog (Drosophila) -2.04001
TMEM35 transmembrane protein 35 -2.0149
PIWIL1 piwi-like RNA-mediated gene silencing 1 -1.98997
MRPS11 mitochondrial ribosomal protein S11 -1.98899
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -1.96798
TRPM3 transient receptor potential cation channel, subfamily M, member 3 -1.95748
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -1.92274
ACSL4 acyl-CoA synthetase long-chain family member 4 -1.90123
EIF3A eukaryotic translation initiation factor 3, subunit A -1.89629
LEF1 lymphoid enhancer-binding factor 1 -1.87973
CNTFR ciliary neurotrophic factor receptor -1.86944
FGF22 fibroblast growth factor 22 -1.86743
TNC tenascin C -1.84982
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -1.84067
IMP3 IMP3, U3 small nucleolar ribonucleoprotein -1.82017
RPL10 ribosomal protein L10 -1.81472
PHEX phosphate regulating endopeptidase homolog, X-linked -1.79334
FEV FEV (ETS oncogene family) -1.7851
OR7C2 olfactory receptor, family 7, subfamily C, member 2 -1.77896
MAPK8 mitogen-activated protein kinase 8 -1.7785
E2F8 E2F transcription factor 8 -1.77822
FZD8 frizzled class receptor 8 -1.7777
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -1.7768
PGK1 phosphoglycerate kinase 1 -1.76716
TGFB2 transforming growth factor, beta 2 -1.75534
LMOD1 leiomodin 1 (smooth muscle) -1.75178
DISC1 disrupted in schizophrenia 1 -1.75144
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 -1.7429
NT5C 5', 3'-nucleotidase, cytosolic -1.73347
CLDN10 claudin 10 -1.73266
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) -1.72733
CLIC2 chloride intracellular channel 2 -1.70393
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 -1.7001
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -1.68764
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -1.68291
STX2 syntaxin 2 -1.67373
GIGYF2 GRB10 interacting GYF protein 2 -1.67316
DAZAP2 DAZ associated protein 2 -1.66921
NEK3 NIMA-related kinase 3 -1.65808
PFDN5 prefoldin subunit 5 -1.6517
TTTY15 testis-specific transcript, Y-linked 15 (non-protein coding) -1.65141
LDHA lactate dehydrogenase A -1.64766
RPS13 ribosomal protein S13 -1.64009
HPS6 Hermansky-Pudlak syndrome 6 -1.63688
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -1.63394
PCDHA10 protocadherin alpha 10 -1.63241
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -1.63046
IDE insulin-degrading enzyme -1.62845
RPLP2 ribosomal protein, large, P2 -1.62832
EIF3F eukaryotic translation initiation factor 3, subunit F -1.62725
ATP7B ATPase, Cu++ transporting, beta polypeptide -1.61949
ERGIC3 ERGIC and golgi 3 -1.61618
COL2A1 collagen, type II, alpha 1 -1.61598
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -1.61114
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 -1.60914
RPL3L ribosomal protein L3-like -1.60032
RPL15 ribosomal protein L15 -1.59844
CST3 cystatin C -1.59831
RNF115 ring finger protein 115 -1.588
ZDHHC17 zinc finger, DHHC-type containing 17 -1.58262
SMAD2 SMAD family member 2 -1.58237
GRIK3 glutamate receptor, ionotropic, kainate 3 -1.57288
RANGRF RAN guanine nucleotide release factor -1.57219
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) -1.56935
ESD esterase D -1.56541
ELMO1 engulfment and cell motility 1 -1.56316
MRPL23 mitochondrial ribosomal protein L23 -1.5612
FECH ferrochelatase -1.55988
CD248 CD248 molecule, endosialin -1.55947
NLRP3 NLR family, pyrin domain containing 3 -1.55111
ARL3 ADP-ribosylation factor-like 3 -1.54431
CDH12 cadherin 12, type 2 (N-cadherin 2) -1.53945
CTBP1 C-terminal binding protein 1 -1.53914
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 -1.53355
MTERF4 mitochondrial transcription termination factor 4 -1.52406
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -1.52156
MYT1 myelin transcription factor 1 -1.52017
IRF7 interferon regulatory factor 7 -1.51981
SMYD3 SET and MYND domain containing 3 -1.5187
SLCO1C1 solute carrier organic anion transporter family, member 1C1 -1.51068
HINT1 histidine triad nucleotide binding protein 1 -1.50518
CEP290 centrosomal protein 290kDa -1.50239
MAEA macrophage erythroblast attacher -1.5017
PCDH11Y protocadherin 11 Y-linked -1.49859
RPL7A ribosomal protein L7a -1.49815
LNPEP leucyl/cystinyl aminopeptidase -1.49777
PIAS2 protein inhibitor of activated STAT, 2 -1.49364
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled -1.4932
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein -1.48908
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -1.48864
TRIP12 thyroid hormone receptor interactor 12 -1.4788
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 -1.47604
NRXN2 neurexin 2 -1.47427
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -1.47102
FNDC3A fibronectin type III domain containing 3A -1.46415
RSAD1 radical S-adenosyl methionine domain containing 1 -1.46397
KIAA1033 KIAA1033 -1.46375
RPL38 ribosomal protein L38 -1.45972
PRPF4B pre-mRNA processing factor 4B -1.4592
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) -1.45691
CAPN9 calpain 9 -1.45156
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -1.4514
ZNF277 zinc finger protein 277 -1.44748
NUP98 nucleoporin 98kDa -1.44327
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 -1.44063
HDC histidine decarboxylase -1.4321
MAPRE2 microtubule-associated protein, RP/EB family, member 2 -1.43094
IL26 interleukin 26 -1.43041
TBX21 T-box 21 -1.4219
IGBP1 immunoglobulin (CD79A) binding protein 1 -1.4204
SKP1 S-phase kinase-associated protein 1 -1.41768
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide -1.41724
MSH4 mutS homolog 4 -1.41686
EEF1B2 eukaryotic translation elongation factor 1 beta 2 -1.41639