HC toxin-909 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the HC toxin-909 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
ANG angiogenin, ribonuclease, RNase A family, 5
ANXA1 annexin A1
ARL4D ADP-ribosylation factor-like 4D
ARMCX2 armadillo repeat containing, X-linked 2
C16ORF45 chromosome 16 open reading frame 45
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLGN calmegin
CLMN calmin (calponin-like, transmembrane)
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CYLD cylindromatosis (turban tumor syndrome)
DEGS1 delta(4)-desaturase, sphingolipid 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DIXDC1 DIX domain containing 1
DLX2 distal-less homeobox 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
ELOVL4 ELOVL fatty acid elongase 4
EPOR erythropoietin receptor
FHL1 four and a half LIM domains 1
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GEM GTP binding protein overexpressed in skeletal muscle
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GRK5 G protein-coupled receptor kinase 5
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HMGN5 high mobility group nucleosome binding domain 5
HOXA1 homeobox A1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ITM2C integral membrane protein 2C
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KIAA0513 KIAA0513
KIAA0895 KIAA0895
KIF13B kinesin family member 13B
KIF21B kinesin family member 21B
KIF5C kinesin family member 5C
LARP6 La ribonucleoprotein domain family, member 6
LIMA1 LIM domain and actin binding 1
LIMCH1 LIM and calponin homology domains 1
LINC00341 long intergenic non-protein coding RNA 341
LPIN1 lipin 1
LRRC49 leucine rich repeat containing 49
LYST lysosomal trafficking regulator
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP1B microtubule-associated protein 1B
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MAST3 microtubule associated serine/threonine kinase 3
MLF1 myeloid leukemia factor 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMD monocyte to macrophage differentiation-associated
NDRG1 N-myc downstream regulated 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
OASL 2'-5'-oligoadenylate synthetase-like
PADI3 peptidyl arginine deiminase, type III
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLLP plasmolipin
PRPH peripherin
PTCH1 patched 1
RAB3A RAB3A, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
REEP1 receptor accessory protein 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNASE4 ribonuclease, RNase A family, 4
RPL3L ribosomal protein L3-like
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SH3GL3 SH3-domain GRB2-like 3
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SSBP2 single-stranded DNA binding protein 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STON1 stonin 1
STXBP1 syntaxin binding protein 1
TBXA2R thromboxane A2 receptor
TEX14 testis expressed 14
TUBA4A tubulin, alpha 4a
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADNP activity-dependent neuroprotector homeobox
AKAP8 A kinase (PRKA) anchor protein 8
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARMC6 armadillo repeat containing 6
BANP BTG3 associated nuclear protein
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C19ORF40 chromosome 19 open reading frame 40
C9ORF91 chromosome 9 open reading frame 91
CALHM2 calcium homeostasis modulator 2
CASD1 CAS1 domain containing 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CHST10 carbohydrate sulfotransferase 10
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CXCL12 chemokine (C-X-C motif) ligand 12
DKK1 dickkopf WNT signaling pathway inhibitor 1
EFNA1 ephrin-A1
EGR3 early growth response 3
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ESRP2 epithelial splicing regulatory protein 2
FAM53B family with sequence similarity 53, member B
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOXC1 forkhead box C1
GABPB1 GA binding protein transcription factor, beta subunit 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GMEB2 glucocorticoid modulatory element binding protein 2
GPR87 G protein-coupled receptor 87
GPRC5C G protein-coupled receptor, class C, group 5, member C
GTF2IRD1 GTF2I repeat domain containing 1
HIRIP3 HIRA interacting protein 3
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX4 iroquois homeobox 4
IRX5 iroquois homeobox 5
ITPKB inositol-trisphosphate 3-kinase B
KAT7 K(lysine) acetyltransferase 7
KCTD15 potassium channel tetramerization domain containing 15
KEAP1 kelch-like ECH-associated protein 1
KIAA0125 KIAA0125
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LUC7L2 LUC7-like 2 (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NPY5R neuropeptide Y receptor Y5
NRIP1 nuclear receptor interacting protein 1
NSD1 nuclear receptor binding SET domain protein 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCNT pericentrin
PHLDA3 pleckstrin homology-like domain, family A, member 3
POGK pogo transposable element with KRAB domain
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
PPAN peter pan homolog (Drosophila)
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRKX protein kinase, X-linked
PRR7 proline rich 7 (synaptic)
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SMG9 SMG9 nonsense mediated mRNA decay factor
SMYD5 SMYD family member 5
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STAG1 stromal antigen 1
STC2 stanniocalcin 2
STRN4 striatin, calmodulin binding protein 4
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
THEM6 thioesterase superfamily member 6
TRIB3 tribbles pseudokinase 3
TRIM8 tripartite motif containing 8
TSKU tsukushi, small leucine rich proteoglycan
TUBA3D tubulin, alpha 3d
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF675 zinc finger protein 675
ZNF692 zinc finger protein 692
ZNF787 zinc finger protein 787
ZNHIT2 zinc finger, HIT-type containing 2