HAND1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description heart and neural crest derivatives expressed 1|The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9421)
External Link http://www.ncbi.nlm.nih.gov/gene/9421
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12 interacting proteins for HAND1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACHE acetylcholinesterase (Yt blood group)
FHL2 four and a half LIM domains 2
HAND2 heart and neural crest derivatives expressed 2
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HEYL hes-related family bHLH transcription factor with YRPW motif-like
MYOD1 myogenic differentiation 1
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
SRA1 steroid receptor RNA activator 1
TCF12 transcription factor 12
TCF3 transcription factor 3