H-89-6878 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the H-89-6878 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALG12 ALG12, alpha-1,6-mannosyltransferase
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARNT aryl hydrocarbon receptor nuclear translocator
ARTN artemin
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASB1 ankyrin repeat and SOCS box containing 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATRN attractin
CASP1 caspase 1, apoptosis-related cysteine peptidase
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CEP162 centrosomal protein 162kDa
CLIP1 CAP-GLY domain containing linker protein 1
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CRMP1 collapsin response mediator protein 1
CSNK1E casein kinase 1, epsilon
CXORF56 chromosome X open reading frame 56
DACH1 dachshund family transcription factor 1
DAGLA diacylglycerol lipase, alpha
DTNA dystrobrevin, alpha
DYSF dysferlin
ELOVL4 ELOVL fatty acid elongase 4
FAXDC2 fatty acid hydroxylase domain containing 2
FCF1 FCF1 rRNA-processing protein
FNTB farnesyltransferase, CAAX box, beta
FOXN2 forkhead box N2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GON4L gon-4-like (C. elegans)
GRK5 G protein-coupled receptor kinase 5
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HCFC1 host cell factor C1
HEXA hexosaminidase A (alpha polypeptide)
HIPK2 homeodomain interacting protein kinase 2
HPS1 Hermansky-Pudlak syndrome 1
IFI6 interferon, alpha-inducible protein 6
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KIAA0754 KIAA0754
LIMCH1 LIM and calponin homology domains 1
LINC00597 long intergenic non-protein coding RNA 597
LMNA lamin A/C
LOXL3 lysyl oxidase-like 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MCM3AP minichromosome maintenance complex component 3 associated protein
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MT1E metallothionein 1E
MVD mevalonate (diphospho) decarboxylase
MVP major vault protein
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NDE1 nudE neurodevelopment protein 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
OGFR opioid growth factor receptor
PBX2 pre-B-cell leukemia homeobox 2
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PHC1 polyhomeotic homolog 1 (Drosophila)
PIAS4 protein inhibitor of activated STAT, 4
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PRICKLE3 prickle homolog 3 (Drosophila)
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPRA protein tyrosine phosphatase, receptor type, A
PVT1 Pvt1 oncogene (non-protein coding)
PXN paxillin
QKI QKI, KH domain containing, RNA binding
RARG retinoic acid receptor, gamma
RGS10 regulator of G-protein signaling 10
RGS14 regulator of G-protein signaling 14
RNF19B ring finger protein 19B
RPL35A ribosomal protein L35a
SDC2 syndecan 2
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNAP23 synaptosomal-associated protein, 23kDa
SNX15 sorting nexin 15
SS18 synovial sarcoma translocation, chromosome 18
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like
TAPBP TAP binding protein (tapasin)
TMEM259 transmembrane protein 259
TRABD TraB domain containing
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TRIM3 tripartite motif containing 3
TRIM66 tripartite motif containing 66
TTLL3 tubulin tyrosine ligase-like family member 3
UBXN6 UBX domain protein 6
VARS valyl-tRNA synthetase
WSB1 WD repeat and SOCS box containing 1
XYLB xylulokinase homolog (H. influenzae)
ZCCHC4 zinc finger, CCHC domain containing 4
ZFP36L2 ZFP36 ring finger protein-like 2
ZMYM2 zinc finger, MYM-type 2
ZNF292 zinc finger protein 292
ZNF324 zinc finger protein 324
ZNF419 zinc finger protein 419

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADM adrenomedullin
AMT aminomethyltransferase
APOM apolipoprotein M
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BFSP1 beaded filament structural protein 1, filensin
C7ORF43 chromosome 7 open reading frame 43
CAPRIN2 caprin family member 2
CDK20 cyclin-dependent kinase 20
CDK6 cyclin-dependent kinase 6
CFAP44 cilia and flagella associated protein 44
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CIDEC cell death-inducing DFFA-like effector c
CLCN6 chloride channel, voltage-sensitive 6
CLSPN claspin
CTSF cathepsin F
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DEPTOR DEP domain containing MTOR-interacting protein
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
EAF2 ELL associated factor 2
ELSPBP1 epididymal sperm binding protein 1
ETV6 ets variant 6
FAM188A family with sequence similarity 188, member A
FBRS fibrosin
FCHSD2 FCH and double SH3 domains 2
FLCN folliculin
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
GDAP1 ganglioside induced differentiation associated protein 1
GDAP2 ganglioside induced differentiation associated protein 2
GFI1 growth factor independent 1 transcription repressor
GMEB1 glucocorticoid modulatory element binding protein 1
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPR157 G protein-coupled receptor 157
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
HOXC4 homeobox C4
HPS6 Hermansky-Pudlak syndrome 6
HSPA2 heat shock 70kDa protein 2
ICK intestinal cell (MAK-like) kinase
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
KLF3 Kruppel-like factor 3 (basic)
LHX6 LIM homeobox 6
LIME1 Lck interacting transmembrane adaptor 1
MANEA mannosidase, endo-alpha
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCC mutated in colorectal cancers
MITF microphthalmia-associated transcription factor
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MYO3A myosin IIIA
NDRG1 N-myc downstream regulated 1
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NEK11 NIMA-related kinase 11
NKRF NFKB repressing factor
NLRX1 NLR family member X1
NSUN3 NOP2/Sun domain family, member 3
PADI3 peptidyl arginine deiminase, type III
PCOLCE procollagen C-endopeptidase enhancer
PDE8B phosphodiesterase 8B
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PITX2 paired-like homeodomain 2
PKD2L1 polycystic kidney disease 2-like 1
PLCD1 phospholipase C, delta 1
PMCH pro-melanin-concentrating hormone
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RAB23 RAB23, member RAS oncogene family
RGS2 regulator of G-protein signaling 2
RHOBTB2 Rho-related BTB domain containing 2
RIN1 Ras and Rab interactor 1
RNF43 ring finger protein 43
RPAP1 RNA polymerase II associated protein 1
RPGR retinitis pigmentosa GTPase regulator
SAA4 serum amyloid A4, constitutive
SCNN1B sodium channel, non voltage gated 1 beta subunit
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SETD1A SET domain containing 1A
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SNTA1 syntrophin, alpha 1
SOAT2 sterol O-acyltransferase 2
SPAG7 sperm associated antigen 7
SREK1IP1 SREK1-interacting protein 1
STRA6 stimulated by retinoic acid 6
STRN striatin, calmodulin binding protein
SYCP2 synaptonemal complex protein 2
TBX19 T-box 19
TGFBR3 transforming growth factor, beta receptor III
TUBA3C tubulin, alpha 3c
VAX2 ventral anterior homeobox 2
ZNF211 zinc finger protein 211
ZNF227 zinc finger protein 227
ZNF354A zinc finger protein 354A
ZNF770 zinc finger protein 770