Gly-His-Lys-6560 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the Gly-His-Lys-6560 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACTN1 actinin, alpha 1
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARHGAP26 Rho GTPase activating protein 26
ARRB2 arrestin, beta 2
ASF1A anti-silencing function 1A histone chaperone
BCAS3 breast carcinoma amplified sequence 3
C16ORF59 chromosome 16 open reading frame 59
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CREB1 cAMP responsive element binding protein 1
CTH cystathionine gamma-lyase
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
DCAF8 DDB1 and CUL4 associated factor 8
DCLRE1C DNA cross-link repair 1C
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
DEAF1 DEAF1 transcription factor
E2F4 E2F transcription factor 4, p107/p130-binding
EFNB1 ephrin-B1
EML3 echinoderm microtubule associated protein like 3
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FADS3 fatty acid desaturase 3
FGF23 fibroblast growth factor 23
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GMIP GEM interacting protein
GOLGA2 golgin A2
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HEMK1 HemK methyltransferase family member 1
HIRA histone cell cycle regulator
HSDL2 hydroxysteroid dehydrogenase like 2
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IKZF5 IKAROS family zinc finger 5 (Pegasus)
KDM2A lysine (K)-specific demethylase 2A
LRRC1 leucine rich repeat containing 1
MAP7 microtubule-associated protein 7
MAX MYC associated factor X
MBD4 methyl-CpG binding domain protein 4
MED15 mediator complex subunit 15
MIIP migration and invasion inhibitory protein
MRPL57 mitochondrial ribosomal protein L57
MYL9 myosin, light chain 9, regulatory
NCAPH2 non-SMC condensin II complex, subunit H2
NCOA3 nuclear receptor coactivator 3
NFYA nuclear transcription factor Y, alpha
NINJ1 ninjurin 1
NOV nephroblastoma overexpressed
NUP210 nucleoporin 210kDa
NUPR1 nuclear protein, transcriptional regulator, 1
OCRL oculocerebrorenal syndrome of Lowe
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PARP3 poly (ADP-ribose) polymerase family, member 3
PCDH9 protocadherin 9
PDAP1 PDGFA associated protein 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PHTF2 putative homeodomain transcription factor 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
POLM polymerase (DNA directed), mu
PPARD peroxisome proliferator-activated receptor delta
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRMT7 protein arginine methyltransferase 7
PROSC proline synthetase co-transcribed homolog (bacterial)
PRR7 proline rich 7 (synaptic)
PTN pleiotrophin
RABIF RAB interacting factor
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPGR retinitis pigmentosa GTPase regulator
RPS9 ribosomal protein S9
SAMD9 sterile alpha motif domain containing 9
SBNO2 strawberry notch homolog 2 (Drosophila)
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SETMAR SET domain and mariner transposase fusion gene
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SMG7 SMG7 nonsense mediated mRNA decay factor
SPTBN1 spectrin, beta, non-erythrocytic 1
ST7 suppression of tumorigenicity 7
TAGLN3 transgelin 3
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TCF3 transcription factor 3
TCP11L1 t-complex 11, testis-specific-like 1
TEX261 testis expressed 261
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TMED2 transmembrane emp24 domain trafficking protein 2
TMEM80 transmembrane protein 80
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNPO2 transportin 2
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VCAN versican
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZNF174 zinc finger protein 174
ZNF787 zinc finger protein 787
ZNHIT2 zinc finger, HIT-type containing 2

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ANXA10 annexin A10
APOL6 apolipoprotein L, 6
ARHGAP10 Rho GTPase activating protein 10
ARPIN actin-related protein 2/3 complex inhibitor
ATG10 autophagy related 10
BEX1 brain expressed, X-linked 1
BIRC3 baculoviral IAP repeat containing 3
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C4ORF19 chromosome 4 open reading frame 19
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCDC94 coiled-coil domain containing 94
CD34 CD34 molecule
CDT1 chromatin licensing and DNA replication factor 1
CES3 carboxylesterase 3
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLDN1 claudin 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPED1 cadherin-like and PC-esterase domain containing 1
CTC1 CTS telomere maintenance complex component 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNMBP dynamin binding protein
DPF3 D4, zinc and double PHD fingers, family 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
FAT4 FAT atypical cadherin 4
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FOXC1 forkhead box C1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GMEB1 glucocorticoid modulatory element binding protein 1
GRM6 glutamate receptor, metabotropic 6
HDAC7 histone deacetylase 7
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HHIPL2 HHIP-like 2
HIST1H2AL histone cluster 1, H2al
HIST1H3G histone cluster 1, H3g
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLX H2.0-like homeobox
HS1BP3 HCLS1 binding protein 3
HSF2BP heat shock transcription factor 2 binding protein
IL12A interleukin 12A
IL33 interleukin 33
INF2 inverted formin, FH2 and WH2 domain containing
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IPO8 importin 8
ITPKA inositol-trisphosphate 3-kinase A
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KDM7A lysine (K)-specific demethylase 7A
KIF13A kinesin family member 13A
KIRREL kin of IRRE like (Drosophila)
KPTN kaptin (actin binding protein)
KRT86 keratin 86, type II
LINC00341 long intergenic non-protein coding RNA 341
LOC390998 ribosomal protein L10 pseudogene
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRC8E leucine rich repeat containing 8 family, member E
LRRK1 leucine-rich repeat kinase 1
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYPD3 LY6/PLAUR domain containing 3
MAPK12 mitogen-activated protein kinase 12
MCMBP minichromosome maintenance complex binding protein
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
NID2 nidogen 2 (osteonidogen)
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
PAIP2B poly(A) binding protein interacting protein 2B
PAN2 PAN2 poly(A) specific ribonuclease subunit
PARD6A par-6 family cell polarity regulator alpha
PBLD phenazine biosynthesis-like protein domain containing
PEX26 peroxisomal biogenesis factor 26
PLEKHO1 pleckstrin homology domain containing, family O member 1
PODNL1 podocan-like 1
PRAME preferentially expressed antigen in melanoma
PRTN3 proteinase 3
PTK6 protein tyrosine kinase 6
RAB23 RAB23, member RAS oncogene family
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL10L ribosomal protein L10-like
SGK2 serum/glucocorticoid regulated kinase 2
SLC12A8 solute carrier family 12, member 8
SLC12A9 solute carrier family 12, member 9
SNHG20 small nucleolar RNA host gene 20
SSTR5 somatostatin receptor 5
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SYT17 synaptotagmin XVII
TBKBP1 TBK1 binding protein 1
THRAP3 thyroid hormone receptor associated protein 3
TMEM132A transmembrane protein 132A
TMEM53 transmembrane protein 53
TMSB15A thymosin beta 15a
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TUBG2 tubulin, gamma 2
WNT10B wingless-type MMTV integration site family, member 10B
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZFP30 ZFP30 zinc finger protein
ZNF350 zinc finger protein 350
ZNF665 zinc finger protein 665
ZNF816 zinc finger protein 816