Glucose Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description disease cluster belonging to disease group metabolic (Genetic Association Database)
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Genes

147 genes associated with the trait Glucose in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
GCK glucokinase (hexokinase 4) 1.37626
IKZF2 IKAROS family zinc finger 2 (Helios) 1.2605
ITPK1 inositol-tetrakisphosphate 1-kinase 1.2532
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 1.23931
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.21571
CCDC88A coiled-coil domain containing 88A 1.13458
PALLD palladin, cytoskeletal associated protein 1.1337
MTNR1B melatonin receptor 1B 1.07287
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 1.05058
ZNF286B zinc finger protein 286B 1.02994
TENM2 teneurin transmembrane protein 2 1.02248
ADGRL2 adhesion G protein-coupled receptor L2 0.975626
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.962656
SFPQ splicing factor proline/glutamine-rich 0.933318
IGL immunoglobulin lambda locus 0.928356
MCF2 MCF.2 cell line derived transforming sequence 0.900003
G6PC2 glucose-6-phosphatase, catalytic, 2 0.883819
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.859259
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 0.841219
UNC13C unc-13 homolog C (C. elegans) 0.78745
CTIF CBP80/20-dependent translation initiation factor 0.774289
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5 0.716267
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.684965
NCSTN nicastrin 0.682098
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.66296
DSG2 desmoglein 2 0.596674
HPS4 Hermansky-Pudlak syndrome 4 0.531459
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) 0.510932
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.461664
LARGE like-glycosyltransferase 0.44447
TMEM132D transmembrane protein 132D 0.440903
PDE8A phosphodiesterase 8A 0.420336
TENM4 teneurin transmembrane protein 4 0.417588
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.416398
SDK2 sidekick cell adhesion molecule 2 0.392858
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 0.385116
RGS7 regulator of G-protein signaling 7 0.376943
TFIP11 tuftelin interacting protein 11 0.367829
CREG2 cellular repressor of E1A-stimulated genes 2 0.359391
NTM neurotrimin 0.345642
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.33567
CLIP4 CAP-GLY domain containing linker protein family, member 4 0.331979
PRLR prolactin receptor 0.294669
CNTN4 contactin 4 0.293813
KIF16B kinesin family member 16B 0.284315
BCL2 B-cell CLL/lymphoma 2 0.284233
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 0.279006
RYR3 ryanodine receptor 3 0.268716
ANO2 anoctamin 2, calcium activated chloride channel 0.265465
MAN2A1 mannosidase, alpha, class 2A, member 1 0.261123
MAN1A1 mannosidase, alpha, class 1A, member 1 0.255322
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.251057
ARHGAP42 Rho GTPase activating protein 42 0.243604
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 0.242525
PDZD2 PDZ domain containing 2 0.237882
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 0.235946
USH2A Usher syndrome 2A (autosomal recessive, mild) 0.23447
ATRNL1 attractin-like 1 0.2293
PGPEP1L pyroglutamyl-peptidase I-like 0.225418
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 0.214522
CCDC33 coiled-coil domain containing 33 0.211796
FAM118A family with sequence similarity 118, member A 0.21034
PANX1 pannexin 1 0.21026
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.207459
USP45 ubiquitin specific peptidase 45 0.202264
TTC23L tetratricopeptide repeat domain 23-like 0.197493
GPM6A glycoprotein M6A 0.184173
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 0.18223
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1 0.176359
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 0.17363
TRA T cell receptor alpha locus 0.166871
MICU3 mitochondrial calcium uptake family, member 3 0.16665
SV2B synaptic vesicle glycoprotein 2B 0.165927
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial 0.162486
DNAJB7 DnaJ (Hsp40) homolog, subfamily B, member 7 0.162486
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 0.159871
FGD3 FYVE, RhoGEF and PH domain containing 3 0.157644
COL19A1 collagen, type XIX, alpha 1 0.156198
ACER2 alkaline ceramidase 2 0.15617
FAM19A4 family with sequence similarity 19 (chemokine (C-C motif)-like), member A4 0.155693
ZBTB16 zinc finger and BTB domain containing 16 0.154858
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.152967
FAM49B family with sequence similarity 49, member B 0.152859
GPC5 glypican 5 0.149793
ODF1 outer dense fiber of sperm tails 1 0.145209
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.142887
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.142045
MITF microphthalmia-associated transcription factor 0.137809
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.137705
TXNRD1 thioredoxin reductase 1 0.137035
MIDN midnolin 0.13683
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.133606
RIMS2 regulating synaptic membrane exocytosis 2 0.132939
UNC5C unc-5 homolog C (C. elegans) 0.132686
ANKRD53 ankyrin repeat domain 53 0.132522
APOLD1 apolipoprotein L domain containing 1 0.131694
RNF149 ring finger protein 149 0.125384
KCTD19 potassium channel tetramerization domain containing 19 0.121326
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 0.121326
OSBPL3 oxysterol binding protein-like 3 0.120522
ASTN2 astrotactin 2 0.120278
RPP30 ribonuclease P/MRP 30kDa subunit 0.117696
ACACB acetyl-CoA carboxylase beta 0.116644
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.113559
ABI3BP ABI family, member 3 (NESH) binding protein 0.111436
SAMD3 sterile alpha motif domain containing 3 0.111113
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.109341
SYN3 synapsin III 0.108967
WDFY4 WDFY family member 4 0.108126
TMEM100 transmembrane protein 100 0.102079
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.101407
TBC1D15 TBC1 domain family, member 15 0.100848
LRRC36 leucine rich repeat containing 36 0.099633
MED11 mediator complex subunit 11 0.098085
CXCL16 chemokine (C-X-C motif) ligand 16 0.098085
EDIL3 EGF-like repeats and discoidin I-like domains 3 0.096238
FAM83H family with sequence similarity 83, member H 0.094059
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 0.091603
NRG3 neuregulin 3 0.089259
PLIN3 perilipin 3 0.088315
PHACTR2 phosphatase and actin regulator 2 0.088229
SNX10 sorting nexin 10 0.086162
TMEM108 transmembrane protein 108 0.085943
SAP30L SAP30-like 0.085476
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 0.085308
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.084339
CDH20 cadherin 20, type 2 0.083367
MOB3A MOB kinase activator 3A 0.076527
PYHIN1 pyrin and HIN domain family, member 1 0.070401
DTD1 D-tyrosyl-tRNA deacylase 1 0.070077
FAM19A1 family with sequence similarity 19 (chemokine (C-C motif)-like), member A1 0.069901
TTLL11 tubulin tyrosine ligase-like family member 11 0.067532
SH3BGR SH3 domain binding glutamate-rich protein 0.067278
FAM20A family with sequence similarity 20, member A 0.067151
LINC00483 long intergenic non-protein coding RNA 483 0.066063
KDM3A lysine (K)-specific demethylase 3A 0.064949
NCKAP5 NCK-associated protein 5 0.063995
DLG2 discs, large homolog 2 (Drosophila) 0.062334
MRPS18A mitochondrial ribosomal protein S18A 0.062267
PDE11A phosphodiesterase 11A 0.061188
PTPRG protein tyrosine phosphatase, receptor type, G 0.061122
COBL cordon-bleu WH2 repeat protein 0.061106
TSPAN18 tetraspanin 18 0.060323
ATP10A ATPase, class V, type 10A 0.060111
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.059736
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 0.05857
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 0.058038