Glioma Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A cell type cancer that has_material_basis_in glial cells and is located_in brain or located_in spine. (Human Disease Ontology, DOID_3070)
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Genes

430 genes associated with the Glioma phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABHD16A abhydrolase domain containing 16A
ACAA1 acetyl-CoA acyltransferase 1
ACAD11 acyl-CoA dehydrogenase family, member 11
ADAM19 ADAM metallopeptidase domain 19
ADAM33 ADAM metallopeptidase domain 33
ADAP1 ArfGAP with dual PH domains 1
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALAD aminolevulinate dehydratase
ALOX12 arachidonate 12-lipoxygenase
ALOX12B arachidonate 12-lipoxygenase, 12R type
ALOX15 arachidonate 15-lipoxygenase
ALOX15B arachidonate 15-lipoxygenase, type B
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ALOXE3 arachidonate lipoxygenase 3
APC adenomatous polyposis coli
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOA2 apolipoprotein A-II
AR androgen receptor
ARCN1 archain 1
ARFRP1 ADP-ribosylation factor related protein 1
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATG9B autophagy related 9B
ATM ATM serine/threonine kinase
ATRX alpha thalassemia/mental retardation syndrome X-linked
BCL2 B-cell CLL/lymphoma 2
BPI bactericidal/permeability-increasing protein
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTBD2 BTB (POZ) domain containing 2
C10ORF88 chromosome 10 open reading frame 88
C1D C1D nuclear receptor corepressor
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QBP complement component 1, q subcomponent binding protein
C1QC complement component 1, q subcomponent, C chain
C1RL complement component 1, r subcomponent-like
C1S complement component 1, s subcomponent
C2 complement component 2
C3 complement component 3
C4BPA complement component 4 binding protein, alpha
C4BPB complement component 4 binding protein, beta
C5 complement component 5
C5AR1 complement component 5a receptor 1
C6 complement component 6
C7 complement component 7
C8A complement component 8, alpha polypeptide
C8B complement component 8, beta polypeptide
C8G complement component 8, gamma polypeptide
C9 complement component 9
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAT catalase
CCDC26 CCDC26 long non-coding RNA
CCL1 chemokine (C-C motif) ligand 1
CCL11 chemokine (C-C motif) ligand 11
CCL13 chemokine (C-C motif) ligand 13
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCL24 chemokine (C-C motif) ligand 24
CCL26 chemokine (C-C motif) ligand 26
CCL5 chemokine (C-C motif) ligand 5
CCL7 chemokine (C-C motif) ligand 7
CCL8 chemokine (C-C motif) ligand 8
CCND1 cyclin D1
CCNH cyclin H
CCR1 chemokine (C-C motif) receptor 1
CCR3 chemokine (C-C motif) receptor 3
CCR4 chemokine (C-C motif) receptor 4
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CCR8 chemokine (C-C motif) receptor 8
CCR9 chemokine (C-C motif) receptor 9
CD14 CD14 molecule
CD180 CD180 molecule
CD2 CD2 molecule
CD209 CD209 molecule
CD46 CD46 molecule, complement regulatory protein
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD93 CD93 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2B-AS1 CDKN2B antisense RNA 1
CFB complement factor B
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CLCA1 chloride channel accessory 1
CLCA2 chloride channel accessory 2
CLOCK clock circadian regulator
CLPTM1L CLPTM1-like
CNR1 cannabinoid receptor 1 (brain)
CNTNAP1 contactin associated protein 1
CORO1C coronin, actin binding protein, 1C
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRP C-reactive protein, pentraxin-related
CRY1 cryptochrome circadian clock 1
CRY2 cryptochrome circadian clock 2
CSNK1E casein kinase 1, epsilon
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CYBA cytochrome b-245, alpha polypeptide
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DCLRE1C DNA cross-link repair 1C
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DEFA3 defensin, alpha 3, neutrophil-specific
DEFA4 defensin, alpha 4, corticostatin
DEFA5 defensin, alpha 5, Paneth cell-specific
DEFA6 defensin, alpha 6, Paneth cell-specific
DEFB1 defensin, beta 1
DEFB118 defensin, beta 118
DEFB119 defensin, beta 119
DEFB126 defensin, beta 126
DEFB127 defensin, beta 127
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33
DLG5 discs, large homolog 5 (Drosophila)
DMBT1 deleted in malignant brain tumors 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EME1 essential meiotic structure-specific endonuclease 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
ERCC6 excision repair cross-complementation group 6
F13A1 coagulation factor XIII, A1 polypeptide
F5 coagulation factor V (proaccelerin, labile factor)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FEN1 flap structure-specific endonuclease 1
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FLJ90680 FLJ90680 protein
FLT3 fms-related tyrosine kinase 3
FOXJ2 forkhead box J2
GC group-specific component (vitamin D binding protein)
GEN1 GEN1 Holliday junction 5' flap endonuclease
GGCT gamma-glutamylcyclotransferase
GLS glutaminase
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR108 G protein-coupled receptor 108
GPX1 glutathione peroxidase 1
GSTM1 glutathione S-transferase mu 1
GSTM3 glutathione S-transferase mu 3 (brain)
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
H2AFX H2A histone family, member X
H3F3A H3 histone, family 3A
HES7 hes family bHLH transcription factor 7
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HMGA2 high mobility group AT-hook 2
HNF1A HNF1 homeobox A
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICAM1 intercellular adhesion molecule 1
ICAM2 intercellular adhesion molecule 2
ICAM3 intercellular adhesion molecule 3
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
ICAM5 intercellular adhesion molecule 5, telencephalin
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IL10 interleukin 10
IL11RA interleukin 11 receptor, alpha
IL12A interleukin 12A
IL12B interleukin 12B
IL13 interleukin 13
IL17C interleukin 17C
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL22 interleukin 22
IL22RA2 interleukin 22 receptor, alpha 2
IL27 interleukin 27
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5RA interleukin 5 receptor, alpha
IL6 interleukin 6
IL7 interleukin 7
INSL3 insulin-like 3 (Leydig cell)
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK3 interleukin-1 receptor-associated kinase 3
IRAK4 interleukin-1 receptor-associated kinase 4
IRGM immunity-related GTPase family, M
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHL30 kelch-like family member 30
KLK1 kallikrein 1
KLK15 kallikrein-related peptidase 15
KLK2 kallikrein-related peptidase 2
KLK4 kallikrein-related peptidase 4
KLK6 kallikrein-related peptidase 6
KLK7 kallikrein-related peptidase 7
KLKB1 kallikrein B, plasma (Fletcher factor) 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LBP lipopolysaccharide binding protein
LGALS3 lectin, galactoside-binding, soluble, 3
LIG1 ligase I, DNA, ATP-dependent
LIG4 ligase IV, DNA, ATP-dependent
LMAN1 lectin, mannose-binding, 1
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase
LOX lysyl oxidase
LPO lactoperoxidase
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3
LRP5 low density lipoprotein receptor-related protein 5
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRC31 leucine rich repeat containing 31
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LY6G6D lymphocyte antigen 6 complex, locus G6D
LY96 lymphocyte antigen 96
MAL mal, T-cell differentiation protein
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MASP2 mannan-binding lectin serine peptidase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MBP myelin basic protein
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEFV Mediterranean fever
MGMT O-6-methylguanine-DNA methyltransferase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR146A microRNA 146a
MIR149 microRNA 149
MIR196A2 microRNA 196a-2
MMP3 matrix metallopeptidase 3
MPO myeloperoxidase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSH2 mutS homolog 2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MUC6 mucin 6, oligomeric mucus/gel-forming
MUC7 mucin 7, secreted
MUS81 MUS81 structure-specific endonuclease subunit
MUTYH mutY homolog
MYB v-myb avian myeloblastosis viral oncogene homolog
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYD88 myeloid differentiation primary response 88
MYRIP myosin VIIA and Rab interacting protein
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NADSYN1 NAD synthetase 1
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NBN nibrin
NCF2 neutrophil cytosolic factor 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NF1 neurofibromin 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NIPAL4 NIPA-like domain containing 4
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPAS2 neuronal PAS domain protein 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
NUMBL numb homolog (Drosophila)-like
OGG1 8-oxoguanine DNA glycosylase
OR10J3 olfactory receptor, family 10, subfamily J, member 3
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
PARP1 poly (ADP-ribose) polymerase 1
PCNA proliferating cell nuclear antigen
PDCD10 programmed cell death 10
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PER1 period circadian clock 1
PER3 period circadian clock 3
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
POLB polymerase (DNA directed), beta
POMT1 protein-O-mannosyltransferase 1
PON1 paraoxonase 1
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRKCA protein kinase C, alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT8 protein arginine methyltransferase 8
PTEN phosphatase and tensin homolog
PTGDR prostaglandin D2 receptor (DP)
PTGDR2 prostaglandin D2 receptor 2
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAD23B RAD23 homolog B (S. cerevisiae)
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RAD51B RAD51 paralog B
RAD52 RAD52 homolog (S. cerevisiae)
RAD54B RAD54 homolog B (S. cerevisiae)
RAD54L RAD54-like (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAG1 recombination activating gene 1
RAVER1 ribonucleoprotein, PTB-binding 1
RBBP6 retinoblastoma binding protein 6
RPA3 replication protein A3, 14kDa
RPA4 replication protein A4, 30kDa
RPS4XP13 ribosomal protein S4X pseudogene 13
RTEL1 regulator of telomere elongation helicase 1
RTEL1-TNFRSF6B RTEL1-TNFRSF6B readthrough (NMD candidate)
SCAF4 SR-related CTD-associated factor 4
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SECTM1 secreted and transmembrane 1
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SETD2 SET domain containing 2
SHFM1 split hand/foot malformation (ectrodactyly) type 1
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC2A4RG SLC2A4 regulator
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SMAD3 SMAD family member 3
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SOCS1 suppressor of cytokine signaling 1
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOCS4 suppressor of cytokine signaling 4
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
SOS1 son of sevenless homolog 1 (Drosophila)
SOX5 SRY (sex determining region Y)-box 5
SPOP speckle-type POZ protein
SPP1 secreted phosphoprotein 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK19 serine/threonine kinase 19
SYK spleen tyrosine kinase
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TICAM1 toll-like receptor adaptor molecule 1
TLR1 toll-like receptor 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TLR9 toll-like receptor 9
TMCO6 transmembrane and coiled-coil domains 6
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOLLIP toll interacting protein
TP53 tumor protein p53
TRAM1 translocation associated membrane protein 1
TREH trehalase (brush-border membrane glycoprotein)
TSLP thymic stromal lymphopoietin
TWF1 twinfilin actin binding protein 1
TWF2 twinfilin actin binding protein 2
TXN thioredoxin
TYK2 tyrosine kinase 2
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
WDHD1 WD repeat and HMG-box DNA binding protein 1
WRN Werner syndrome, RecQ helicase-like
WWOX WW domain containing oxidoreductase
XDH xanthine dehydrogenase
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZBTB46 zinc finger and BTB domain containing 46
ZGPAT zinc finger, CCCH-type with G patch domain
ZNF350 zinc finger protein 350
ZNF76 zinc finger protein 76
ZP1 zona pellucida glycoprotein 1 (sperm receptor)