Glioblastoma Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

328 genes associated with the Glioblastoma phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABHD16A abhydrolase domain containing 16A
ACAA1 acetyl-CoA acyltransferase 1
ACAD11 acyl-CoA dehydrogenase family, member 11
ADAM19 ADAM metallopeptidase domain 19
ADAM33 ADAM metallopeptidase domain 33
ADAP1 ArfGAP with dual PH domains 1
ALOX12 arachidonate 12-lipoxygenase
ALOX12B arachidonate 12-lipoxygenase, 12R type
ALOX15 arachidonate 15-lipoxygenase
ALOX15B arachidonate 15-lipoxygenase, type B
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ALOXE3 arachidonate lipoxygenase 3
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOA2 apolipoprotein A-II
AQP1 aquaporin 1 (Colton blood group)
ATG9B autophagy related 9B
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
ATRX alpha thalassemia/mental retardation syndrome X-linked
AURKA aurora kinase A
AURKB aurora kinase B
BCL2 B-cell CLL/lymphoma 2
BPI bactericidal/permeability-increasing protein
BRCA1 breast cancer 1, early onset
C1D C1D nuclear receptor corepressor
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QBP complement component 1, q subcomponent binding protein
C1QC complement component 1, q subcomponent, C chain
C1RL complement component 1, r subcomponent-like
C1S complement component 1, s subcomponent
C2 complement component 2
C3 complement component 3
C4BPA complement component 4 binding protein, alpha
C4BPB complement component 4 binding protein, beta
C5 complement component 5
C5AR1 complement component 5a receptor 1
C6 complement component 6
C7 complement component 7
C8A complement component 8, alpha polypeptide
C8B complement component 8, beta polypeptide
C8G complement component 8, gamma polypeptide
C9 complement component 9
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CCDC26 CCDC26 long non-coding RNA
CCL1 chemokine (C-C motif) ligand 1
CCL11 chemokine (C-C motif) ligand 11
CCL13 chemokine (C-C motif) ligand 13
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCL24 chemokine (C-C motif) ligand 24
CCL26 chemokine (C-C motif) ligand 26
CCL5 chemokine (C-C motif) ligand 5
CCL7 chemokine (C-C motif) ligand 7
CCL8 chemokine (C-C motif) ligand 8
CCR1 chemokine (C-C motif) receptor 1
CCR3 chemokine (C-C motif) receptor 3
CCR4 chemokine (C-C motif) receptor 4
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CCR8 chemokine (C-C motif) receptor 8
CCR9 chemokine (C-C motif) receptor 9
CD14 CD14 molecule
CD180 CD180 molecule
CD209 CD209 molecule
CD46 CD46 molecule, complement regulatory protein
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD93 CD93 molecule
CDK4 cyclin-dependent kinase 4
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CFB complement factor B
CHEK2 checkpoint kinase 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CLCA1 chloride channel accessory 1
CLCA2 chloride channel accessory 2
CNTNAP1 contactin associated protein 1
CORO1C coronin, actin binding protein, 1C
CRP C-reactive protein, pentraxin-related
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CYBA cytochrome b-245, alpha polypeptide
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAXX death-domain associated protein
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DEFA3 defensin, alpha 3, neutrophil-specific
DEFA4 defensin, alpha 4, corticostatin
DEFA5 defensin, alpha 5, Paneth cell-specific
DEFA6 defensin, alpha 6, Paneth cell-specific
DEFB1 defensin, beta 1
DEFB118 defensin, beta 118
DEFB119 defensin, beta 119
DEFB126 defensin, beta 126
DEFB127 defensin, beta 127
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33
DLG5 discs, large homolog 5 (Drosophila)
DMBT1 deleted in malignant brain tumors 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EME1 essential meiotic structure-specific endonuclease 1
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC6 excision repair cross-complementation group 6
EXO1 exonuclease 1
F5 coagulation factor V (proaccelerin, labile factor)
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FGF2 fibroblast growth factor 2 (basic)
FLJ90680 FLJ90680 protein
FLT3 fms-related tyrosine kinase 3
FOXJ2 forkhead box J2
GGCT gamma-glutamylcyclotransferase
GLS glutaminase
GNAS GNAS complex locus
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPR108 G protein-coupled receptor 108
GRIK4 glutamate receptor, ionotropic, kainate 4
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRM1 glutamate receptor, metabotropic 1
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
H3F3A H3 histone, family 3A
HES7 hes family bHLH transcription factor 7
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICAM1 intercellular adhesion molecule 1
ICAM2 intercellular adhesion molecule 2
ICAM3 intercellular adhesion molecule 3
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
ICAM5 intercellular adhesion molecule 5, telencephalin
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IL10 interleukin 10
IL11RA interleukin 11 receptor, alpha
IL13 interleukin 13
IL17C interleukin 17C
IL4 interleukin 4
IL4R interleukin 4 receptor
INSL3 insulin-like 3 (Leydig cell)
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK3 interleukin-1 receptor-associated kinase 3
IRAK4 interleukin-1 receptor-associated kinase 4
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JAK3 Janus kinase 3
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCNG3 potassium channel, voltage gated modifier subfamily G, member 3
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNK1 potassium channel, two pore domain subfamily K, member 1
KDR kinase insert domain receptor
KLK1 kallikrein 1
KLK15 kallikrein-related peptidase 15
KLK2 kallikrein-related peptidase 2
KLK4 kallikrein-related peptidase 4
KLK6 kallikrein-related peptidase 6
KLK7 kallikrein-related peptidase 7
KLKB1 kallikrein B, plasma (Fletcher factor) 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LBP lipopolysaccharide binding protein
LMAN1 lectin, mannose-binding, 1
LPO lactoperoxidase
LRRC4B leucine rich repeat containing 4B
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LY6G6D lymphocyte antigen 6 complex, locus G6D
LY96 lymphocyte antigen 96
MAL mal, T-cell differentiation protein
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MASP2 mannan-binding lectin serine peptidase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MBP myelin basic protein
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEFV Mediterranean fever
MGMT O-6-methylguanine-DNA methyltransferase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MPO myeloperoxidase
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MUC6 mucin 6, oligomeric mucus/gel-forming
MUC7 mucin 7, secreted
MYD88 myeloid differentiation primary response 88
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NBN nibrin
NCF2 neutrophil cytosolic factor 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NIPAL4 NIPA-like domain containing 4
NMUR1 neuromedin U receptor 1
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OR10J3 olfactory receptor, family 10, subfamily J, member 3
PDCD10 programmed cell death 10
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHLDB1 pleckstrin homology-like domain, family B, member 1
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene)
PTEN phosphatase and tensin homolog
PTGDR prostaglandin D2 receptor (DP)
PTGDR2 prostaglandin D2 receptor 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRD protein tyrosine phosphatase, receptor type, D
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAD51L3-RFFL RAD51L3-RFFL readthrough
RAVER1 ribonucleoprotein, PTB-binding 1
RECQL4 RecQ protein-like 4
REN renin
RPS4XP13 ribosomal protein S4X pseudogene 13
RTEL1 regulator of telomere elongation helicase 1
RYR2 ryanodine receptor 2 (cardiac)
RYR3 ryanodine receptor 3
S100B S100 calcium binding protein B
SCAF4 SR-related CTD-associated factor 4
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCN1B sodium channel, voltage gated, type I beta subunit
SCN3A sodium channel, voltage gated, type III alpha subunit
SCN3B sodium channel, voltage gated, type III beta subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SECTM1 secreted and transmembrane 1
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLC9A4 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
SOCS1 suppressor of cytokine signaling 1
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOCS4 suppressor of cytokine signaling 4
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
SSBP2 single-stranded DNA binding protein 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STIM2 stromal interaction molecule 2
STK19 serine/threonine kinase 19
TCN2 transcobalamin II
TERT telomerase reverse transcriptase
TICAM1 toll-like receptor adaptor molecule 1
TLR1 toll-like receptor 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TLR9 toll-like receptor 9
TMCO6 transmembrane and coiled-coil domains 6
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOLLIP toll interacting protein
TP53 tumor protein p53
TRAM1 translocation associated membrane protein 1
TRPM5 transient receptor potential cation channel, subfamily M, member 5
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TSLP thymic stromal lymphopoietin
TWF1 twinfilin actin binding protein 1
TWF2 twinfilin actin binding protein 2
TYK2 tyrosine kinase 2
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
WDHD1 WD repeat and HMG-box DNA binding protein 1
XDH xanthine dehydrogenase
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF76 zinc finger protein 76
ZP1 zona pellucida glycoprotein 1 (sperm receptor)