Gastrointestinal Neoplasms Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D005770
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Genes

120 genes/proteins associated with the disease Gastrointestinal Neoplasms from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 2.88009
ERBB2 erb-b2 receptor tyrosine kinase 2 2.88009
APC adenomatous polyposis coli 2.88009
HIC1 hypermethylated in cancer 1 2.88009
DPYD dihydropyrimidine dehydrogenase 1.92058
TYMS thymidylate synthetase 1.80265
PCNA proliferating cell nuclear antigen 1.62129
H2AFX H2A histone family, member X 1.555
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.5479
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.54232
TP53 tumor protein p53 1.52111
CCNA2 cyclin A2 1.50398
CDK2 cyclin-dependent kinase 2 1.49381
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.49174
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.4817
DDIT3 DNA-damage-inducible transcript 3 1.4817
CDK1 cyclin-dependent kinase 1 1.47064
BIRC5 baculoviral IAP repeat containing 5 1.4449
VEGFA vascular endothelial growth factor A 1.44166
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.43455
TYMP thymidine phosphorylase 1.40623
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.40568
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 1.37275
BCL2 B-cell CLL/lymphoma 2 1.3619
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 1.35734
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.35589
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.35127
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 1.33405
JUN jun proto-oncogene 1.33375
CCND1 cyclin D1 1.32905
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.31387
CDKN2A cyclin-dependent kinase inhibitor 2A 1.31148
MAPK1 mitogen-activated protein kinase 1 1.31119
BAX BCL2-associated X protein 1.30758
CCNB1 cyclin B1 1.30117
GSTP1 glutathione S-transferase pi 1 1.29996
FGF2 fibroblast growth factor 2 (basic) 1.2944
RB1 retinoblastoma 1 1.29379
HRAS Harvey rat sarcoma viral oncogene homolog 1.29103
MCL1 myeloid cell leukemia 1 1.2898
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.28889
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.28518
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.27409
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.27039
CCND3 cyclin D3 1.25807
NQO1 NAD(P)H dehydrogenase, quinone 1 1.25463
PPARG peroxisome proliferator-activated receptor gamma 1.25432
ATF3 activating transcription factor 3 1.23837
CHEK1 checkpoint kinase 1 1.23042
SP1 Sp1 transcription factor 1.23042
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 1.22884
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 1.22566
MAPK3 mitogen-activated protein kinase 3 1.21695
SAT1 spermidine/spermine N1-acetyltransferase 1 1.21435
SOD2 superoxide dismutase 2, mitochondrial 1.21043
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.21043
PARP1 poly (ADP-ribose) polymerase 1 1.2059
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.2059
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.20097
HIST1H4C histone cluster 1, H4c 1.18948
BCL2L1 BCL2-like 1 1.18751
LGALS8 lectin, galactoside-binding, soluble, 8 1.17761
COL1A1 collagen, type I, alpha 1 1.16967
FAS Fas cell surface death receptor 1.142
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.13793
TNF tumor necrosis factor 1.13347
THBS1 thrombospondin 1 1.12219
BID BH3 interacting domain death agonist 1.11775
MAP2K2 mitogen-activated protein kinase kinase 2 1.1122
CFLAR CASP8 and FADD-like apoptosis regulator 1.10907
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.10734
TXNRD1 thioredoxin reductase 1 1.10562
CANX calnexin 1.08513
AKAP12 A kinase (PRKA) anchor protein 12 1.08478
CXCR4 chemokine (C-X-C motif) receptor 4 1.08442
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.08266
TRIB3 tribbles pseudokinase 3 1.08019
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 1.07983
MGMT O-6-methylguanine-DNA methyltransferase 1.07732
PRC1 protein regulator of cytokinesis 1 1.07732
RGS4 regulator of G-protein signaling 4 1.07234
CAV1 caveolin 1, caveolae protein, 22kDa 1.07199
CD44 CD44 molecule (Indian blood group) 1.06917
GSK3B glycogen synthase kinase 3 beta 1.06808
IFNG interferon, gamma 1.06297
S100A10 S100 calcium binding protein A10 1.06225
SQSTM1 sequestosome 1 1.06225
COL1A2 collagen, type I, alpha 2 1.05936
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.05828
PRKCD protein kinase C, delta 1.05535
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 1.05312
IGFBP4 insulin-like growth factor binding protein 4 1.05274
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.05163
GADD45A growth arrest and DNA-damage-inducible, alpha 1.04684
CKS2 CDC28 protein kinase regulatory subunit 2 1.04574
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.04239
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.04201
MSH2 mutS homolog 2 1.03678
CCL2 chemokine (C-C motif) ligand 2 1.03493
PTGES prostaglandin E synthase 1.03271
NFE2L2 nuclear factor, erythroid 2-like 2 1.03122
ACO2 aconitase 2, mitochondrial 1.03009
CXCL8 chemokine (C-X-C motif) ligand 8 1.03009
FUCA1 fucosidase, alpha-L- 1, tissue 1.02858
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.02858
AARS alanyl-tRNA synthetase 1.02746
SEC31A SEC31 homolog A (S. cerevisiae) 1.02746
CDKN3 cyclin-dependent kinase inhibitor 3 1.02336
MMP9 matrix metallopeptidase 9 1.01739
IL1B interleukin 1, beta 1.01739
JUNB jun B proto-oncogene 1.01512
ALB albumin 1.01474
HES1 hes family bHLH transcription factor 1 1.01361
KLF4 Kruppel-like factor 4 (gut) 1.01361
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.01249
TOP2A topoisomerase (DNA) II alpha 170kDa 1.01174
PTEN phosphatase and tensin homolog 1.01174
ERCC1 excision repair cross-complementation group 1 1.01174
IL18 interleukin 18 1.01137
PLAT plasminogen activator, tissue 1.01137