Gastritis Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A stomach disease that is an inflammation of the lining of the stomach. (Human Disease Ontology, DOID_4029)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D005756
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Genes

277 genes/proteins associated with the disease Gastritis from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
MPO myeloperoxidase 2.18513
IL1B interleukin 1, beta 2.06934
TNF tumor necrosis factor 2.06088
CXCL8 chemokine (C-X-C motif) ligand 8 2.01227
HSPA1A heat shock 70kDa protein 1A 2.01078
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.93582
IL6 interleukin 6 1.93008
ICAM1 intercellular adhesion molecule 1 1.80038
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.79675
HMOX1 heme oxygenase 1 1.76733
CAT catalase 1.76347
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.7556
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.74802
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.70471
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.69659
IFNG interferon, gamma 1.69254
DUSP1 dual specificity phosphatase 1 1.68401
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.68169
FOS FBJ murine osteosarcoma viral oncogene homolog 1.67116
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.65113
PCNA proliferating cell nuclear antigen 1.64978
JUN jun proto-oncogene 1.64528
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.64348
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.6278
IGF1 insulin-like growth factor 1 (somatomedin C) 1.62176
ALB albumin 1.60082
NOS2 nitric oxide synthase 2, inducible 1.59474
BAX BCL2-associated X protein 1.59427
VEGFA vascular endothelial growth factor A 1.55599
TIMP2 TIMP metallopeptidase inhibitor 2 1.5528
CCND1 cyclin D1 1.55059
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.5462
IL10 interleukin 10 1.54475
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.54427
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.52865
DDIT3 DNA-damage-inducible transcript 3 1.51557
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.51255
GSTT1 glutathione S-transferase theta 1 1.51105
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.50549
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.50198
GLUL glutamate-ammonia ligase 1.5012
MMP2 matrix metallopeptidase 2 1.49992
PPARG peroxisome proliferator-activated receptor gamma 1.49686
TIMP1 TIMP metallopeptidase inhibitor 1 1.49609
GDF15 growth differentiation factor 15 1.49432
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.48813
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 1.48017
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.47296
COL1A1 collagen, type I, alpha 1 1.46542
SAT1 spermidine/spermine N1-acetyltransferase 1 1.46304
PSAT1 phosphoserine aminotransferase 1 1.45564
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.45431
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.44246
CCL3 chemokine (C-C motif) ligand 3 1.44166
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.44084
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 1.43892
HSF1 heat shock transcription factor 1 1.43892
EGR1 early growth response 1 1.43755
FAS Fas cell surface death receptor 1.43591
MAPK14 mitogen-activated protein kinase 14 1.42428
MAPK3 mitogen-activated protein kinase 3 1.41257
PPARA peroxisome proliferator-activated receptor alpha 1.4076
MAPK1 mitogen-activated protein kinase 1 1.40316
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.40008
LDLR low density lipoprotein receptor 1.39757
CALCA calcitonin-related polypeptide alpha 1.39366
CCL2 chemokine (C-C motif) ligand 2 1.39198
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.39114
CXCL2 chemokine (C-X-C motif) ligand 2 1.38641
PPARD peroxisome proliferator-activated receptor delta 1.38441
AQP4 aquaporin 4 1.36933
TGIF1 TGFB-induced factor homeobox 1 1.36648
FGF2 fibroblast growth factor 2 (basic) 1.36418
CYBA cytochrome b-245, alpha polypeptide 1.36218
CYBB cytochrome b-245, beta polypeptide 1.36047
MCL1 myeloid cell leukemia 1 1.35934
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.35792
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 1.35589
CTSE cathepsin E 1.3556
VCAM1 vascular cell adhesion molecule 1 1.35098
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.35069
SOD2 superoxide dismutase 2, mitochondrial 1.35012
BCL2L1 BCL2-like 1 1.34723
GAST gastrin 1.34694
RB1 retinoblastoma 1 1.34664
SOD1 superoxide dismutase 1, soluble 1.34547
PARP1 poly (ADP-ribose) polymerase 1 1.34518
COL3A1 collagen, type III, alpha 1 1.33995
INSIG1 insulin induced gene 1 1.3382
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.33346
GCLC glutamate-cysteine ligase, catalytic subunit 1.33052
ACTA2 actin, alpha 2, smooth muscle, aorta 1.32786
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.32428
EGF epidermal growth factor 1.32221
IL1A interleukin 1, alpha 1.31985
NFE2L2 nuclear factor, erythroid 2-like 2 1.31716
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.31357
GCLM glutamate-cysteine ligase, modifier subunit 1.31357
MAP2K5 mitogen-activated protein kinase kinase 5 1.31
FABP4 fatty acid binding protein 4, adipocyte 1.30329
FOSL1 FOS-like antigen 1 1.29905
NQO1 NAD(P)H dehydrogenase, quinone 1 1.29011
CREM cAMP responsive element modulator 1.28827
NME2 NME/NM23 nucleoside diphosphate kinase 2 1.28549
TGFB1 transforming growth factor, beta 1 1.28364
EGFR epidermal growth factor receptor 1.28241
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.27039
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.27039
GSR glutathione reductase 1.26794
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.26236
CLNS1A chloride channel, nucleotide-sensitive, 1A 1.26083
CTH cystathionine gamma-lyase 1.25868
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.25682
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.25463
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.25276
CTGF connective tissue growth factor 1.25059
GADD45A growth arrest and DNA-damage-inducible, alpha 1.24905
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 1.24718
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.24718
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.24213
CLU clusterin 1.23584
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.23584
TP53 tumor protein p53 1.23265
TFRC transferrin receptor 1.23074
PRKCB protein kinase C, beta 1.22853
RNASE4 ribonuclease, RNase A family, 4 1.22821
APAF1 apoptotic peptidase activating factor 1 1.22469
CYB5R3 cytochrome b5 reductase 3 1.22209
KEAP1 kelch-like ECH-associated protein 1 1.21271
LPL lipoprotein lipase 1.20946
IRS1 insulin receptor substrate 1 1.20719
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 1.20493
CCNE1 cyclin E1 1.19933
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.199
IL2 interleukin 2 1.19639
SOCS3 suppressor of cytokine signaling 3 1.1908
EDN1 endothelin 1 1.1908
MAP2 microtubule-associated protein 2 1.1862
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.18359
TXNRD1 thioredoxin reductase 1 1.18326
TRIB3 tribbles pseudokinase 3 1.17827
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.17662
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.17596
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.17067
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.16766
CD14 CD14 molecule 1.16766
BCL2 B-cell CLL/lymphoma 2 1.16633
NFIL3 nuclear factor, interleukin 3 regulated 1.166
IGF1R insulin-like growth factor 1 receptor 1.16467
AGTR1 angiotensin II receptor, type 1 1.16368
PHGDH phosphoglycerate dehydrogenase 1.16335
NOS3 nitric oxide synthase 3 (endothelial cell) 1.16269
MMP3 matrix metallopeptidase 3 1.1617
RHBG Rh family, B glycoprotein (gene/pseudogene) 1.16137
IL4 interleukin 4 1.16137
GPX1 glutathione peroxidase 1 1.15763
AHR aryl hydrocarbon receptor 1.14816
UBE2B ubiquitin-conjugating enzyme E2B 1.14781
PLAU plasminogen activator, urokinase 1.14747
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.14713
ANXA3 annexin A3 1.14507
GSK3B glycogen synthase kinase 3 beta 1.14302
THRSP thyroid hormone responsive 1.14268
LEP leptin 1.1403
MT1A metallothionein 1A 1.13758
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 1.13655
HNF4A hepatocyte nuclear factor 4, alpha 1.13621
SDS serine dehydratase 1.13552
SPP1 secreted phosphoprotein 1 1.13552
IGFBP3 insulin-like growth factor binding protein 3 1.13484
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 1.12564
NOX4 NADPH oxidase 4 1.12564
GSTM2 glutathione S-transferase mu 2 (muscle) 1.12426
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.12426
PRDX6 peroxiredoxin 6 1.12357
MSMO1 methylsterol monooxygenase 1 1.12357
FDPS farnesyl diphosphate synthase 1.12151
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.11843
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.11741
CBR1 carbonyl reductase 1 1.11571
MKI67 marker of proliferation Ki-67 1.11536
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.1136
IDI1 isopentenyl-diphosphate delta isomerase 1 1.11325
MMP1 matrix metallopeptidase 1 1.11186
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.11151
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 1.10907
JUNB jun B proto-oncogene 1.10907
CD36 CD36 molecule (thrombospondin receptor) 1.10803
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 1.10734
IL18 interleukin 18 1.10562
H2AFX H2A histone family, member X 1.10562
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.10527
PLAT plasminogen activator, tissue 1.10527
APOE apolipoprotein E 1.10175
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 1.09892
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 1.09857
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.09786
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.09681
S100A9 S100 calcium binding protein A9 1.09401
CREBBP CREB binding protein 1.09226
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 1.0919
CES2 carboxylesterase 2 1.09047
HBEGF heparin-binding EGF-like growth factor 1.08655
CALR calreticulin 1.08301
ODC1 ornithine decarboxylase 1 1.08161
RGS2 regulator of G-protein signaling 2 1.07947
MAL mal, T-cell differentiation protein 1.0784
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.07768
CA2 carbonic anhydrase II 1.07589
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide 1.07553
FASN fatty acid synthase 1.07269
ACADL acyl-CoA dehydrogenase, long chain 1.07234
GPX2 glutathione peroxidase 2 1.07234
THBS1 thrombospondin 1 1.07093
MMP9 matrix metallopeptidase 9 1.07093
HSPB1 heat shock 27kDa protein 1 1.07022
SCD5 stearoyl-CoA desaturase 5 1.06881
POR P450 (cytochrome) oxidoreductase 1.06698
NAP1L1 nucleosome assembly protein 1-like 1 1.06588
DUSP6 dual specificity phosphatase 6 1.0637
ACACA acetyl-CoA carboxylase alpha 1.0637
PNPLA2 patatin-like phospholipase domain containing 2 1.06008
TPM4 tropomyosin 4 1.06008
ACSL1 acyl-CoA synthetase long-chain family member 1 1.05864
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.05864
SRXN1 sulfiredoxin 1 1.05386
CCNA2 cyclin A2 1.05274
PRL prolactin 1.052
TRIB1 tribbles pseudokinase 1 1.05126
ADIPOR2 adiponectin receptor 2 1.05126
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.05052
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.04868
AFP alpha-fetoprotein 1.04868
FGF21 fibroblast growth factor 21 1.04868
HSBP1 heat shock factor binding protein 1 1.04831
EDNRB endothelin receptor type B 1.04538
NPY neuropeptide Y 1.04538
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 1.04538
BAK1 BCL2-antagonist/killer 1 1.04239
CDK2 cyclin-dependent kinase 2 1.04201
ALPL alkaline phosphatase, liver/bone/kidney 1.03939
IL12B interleukin 12B 1.03901
ATF3 activating transcription factor 3 1.03789
RND3 Rho family GTPase 3 1.03752
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.03715
NCF1 neutrophil cytosolic factor 1 1.03604
CNR1 cannabinoid receptor 1 (brain) 1.03604
GLS glutaminase 1.03493
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.03456
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.03308
ZFAND2A zinc finger, AN1-type domain 2A 1.03197
SELL selectin L 1.02971
ENO1 enolase 1, (alpha) 1.02971
IL12A interleukin 12A 1.02858
CTSB cathepsin B 1.02522
IGFBP1 insulin-like growth factor binding protein 1 1.02522
LCN2 lipocalin 2 1.02522
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 1.02373
MGMT O-6-methylguanine-DNA methyltransferase 1.02373
CTSS cathepsin S 1.02373
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.02373
BTG2 BTG family, member 2 1.02373
ATF4 activating transcription factor 4 1.02225
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 1.02114
SDC4 syndecan 4 1.02077
MAPK8 mitogen-activated protein kinase 8 1.01928
LIPC lipase, hepatic 1.01852
SCARB1 scavenger receptor class B, member 1 1.01663
SLC19A1 solute carrier family 19 (folate transporter), member 1 1.01625
SMAD7 SMAD family member 7 1.01625
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.01625
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.01587
CD44 CD44 molecule (Indian blood group) 1.01474
ARC activity-regulated cytoskeleton-associated protein 1.01361
GRIK5 glutamate receptor, ionotropic, kainate 5 1.01324
ACE angiotensin I converting enzyme 1.01212
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 1.01137