Food Hypersensitivity Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A hypersensitivity reaction type I disease that is an abnormal response to a food, triggered by the body's immune system. (Human Disease Ontology, DOID_3044)
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Genes

40 genes associated with the Food Hypersensitivity phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ADAM33 ADAM metallopeptidase domain 33
ADRB2 adrenoceptor beta 2, surface
BTNL2 butyrophilin-like 2
CD14 CD14 molecule
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DAO D-amino-acid oxidase
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FLG filaggrin
GC group-specific component (vitamin D binding protein)
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IFNL3 interferon, lambda 3
IL10 interleukin 10
IL12RB1 interleukin 12 receptor, beta 1
IL13 interleukin 13
IL13RA1 interleukin 13 receptor, alpha 1
IL4 interleukin 4
IL4R interleukin 4 receptor
IL9 interleukin 9
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NLRP3 NLR family, pyrin domain containing 3
PTGDR2 prostaglandin D2 receptor 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SPINK5 serine peptidase inhibitor, Kazal type 5
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TSLP thymic stromal lymphopoietin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor