Fever Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Elevated body temperature due to failed thermoregulation. (Human Phenotype Ontology, HP_0001945)
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Genes

28 genes associated with the Fever phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
CD209 CD209 molecule
CSNK1G2 casein kinase 1, gamma 2
CXCL8 chemokine (C-X-C motif) ligand 8
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
ERCC2 excision repair cross-complementation group 2
G6PD glucose-6-phosphate dehydrogenase
IFNG interferon, gamma
IFNL3 interferon, lambda 3
IL10 interleukin 10
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL6 interleukin 6
LTA lymphotoxin alpha
MBL2 mannose-binding lectin (protein C) 2, soluble
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEFV Mediterranean fever
MVK mevalonate kinase
NLRP3 NLR family, pyrin domain containing 3
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
TGFB1 transforming growth factor, beta 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TP53 tumor protein p53
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1