Fetal Growth Retardation Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description slow or limited development during the fetal period (sensu Mus: from E14 through birth) (Mammalian Phenotype Ontology, MP_0004201)
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Genes

57 genes associated with the Fetal Growth Retardation phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACP1 acid phosphatase 1, soluble
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AK1 adenylate kinase 1
ANXA5 annexin A5
APOB apolipoprotein B
APOE apolipoprotein E
AR androgen receptor
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
COMT catechol-O-methyltransferase
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
EGF epidermal growth factor
F13A1 coagulation factor XIII, A1 polypeptide
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
F8 coagulation factor VIII, procoagulant component
FABP2 fatty acid binding protein 2, intestinal
FAS Fas cell surface death receptor
FGB fibrinogen beta chain
FLT1 fms-related tyrosine kinase 1
GCK glucokinase (hexokinase 4)
GLO1 glyoxalase I
GNAS GNAS complex locus
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IL6 interleukin 6
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK2 Janus kinase 2
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
MBL2 mannose-binding lectin (protein C) 2, soluble
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NOS3 nitric oxide synthase 3 (endothelial cell)
NQO1 NAD(P)H dehydrogenase, quinone 1
PIGF phosphatidylinositol glycan anchor biosynthesis, class F
PON1 paraoxonase 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SOD3 superoxide dismutase 3, extracellular
STOX1 storkhead box 1
THBD thrombomodulin
TNF tumor necrosis factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor