Fetal Diseases Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D005315
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Genes

266 genes/proteins associated with the disease Fetal Diseases from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CHUK conserved helix-loop-helix ubiquitous kinase 2.88009
PRSS8 protease, serine, 8 2.88009
IL6 interleukin 6 2.09603
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.99047
FOS FBJ murine osteosarcoma viral oncogene homolog 1.97997
TNF tumor necrosis factor 1.95285
IFNG interferon, gamma 1.87244
BCL2 B-cell CLL/lymphoma 2 1.86672
NPPA natriuretic peptide A 1.84976
VEGFA vascular endothelial growth factor A 1.83877
CAT catalase 1.78759
IL1B interleukin 1, beta 1.77975
MAPK3 mitogen-activated protein kinase 3 1.75856
MAPK1 mitogen-activated protein kinase 1 1.74984
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.73393
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.67051
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.66835
TP53 tumor protein p53 1.64146
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.62222
CCL2 chemokine (C-C motif) ligand 2 1.61713
REN renin 1.61014
BCL2L1 BCL2-like 1 1.60547
FAS Fas cell surface death receptor 1.60151
JUN jun proto-oncogene 1.60035
IL10 interleukin 10 1.59685
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.5721
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.56435
NPY neuropeptide Y 1.55648
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.55402
KLF4 Kruppel-like factor 4 (gut) 1.5311
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.51557
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.50877
EGR1 early growth response 1 1.50423
PARP1 poly (ADP-ribose) polymerase 1 1.49584
EDN1 endothelin 1 1.49045
BDNF brain-derived neurotrophic factor 1.49045
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.4871
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.46568
NOS3 nitric oxide synthase 3 (endothelial cell) 1.46172
NOS2 nitric oxide synthase 2, inducible 1.4575
BAX BCL2-associated X protein 1.45697
NPPB natriuretic peptide B 1.45484
GJA1 gap junction protein, alpha 1, 43kDa 1.45458
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.44872
MAPK8 mitogen-activated protein kinase 8 1.44436
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.44219
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.43673
CXCL8 chemokine (C-X-C motif) ligand 8 1.43482
DUSP1 dual specificity phosphatase 1 1.43455
STAT5B signal transducer and activator of transcription 5B 1.42642
BID BH3 interacting domain death agonist 1.41119
PCNA proliferating cell nuclear antigen 1.4076
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 1.40677
PRL prolactin 1.40429
IL1A interleukin 1, alpha 1.39394
IL2 interleukin 2 1.39058
GFAP glial fibrillary acidic protein 1.38498
IGF1 insulin-like growth factor 1 (somatomedin C) 1.37761
DDIT3 DNA-damage-inducible transcript 3 1.37047
POMC proopiomelanocortin 1.36791
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.36304
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.36304
ALB albumin 1.36275
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.35242
HSPA8 heat shock 70kDa protein 8 1.34897
TGFB1 transforming growth factor, beta 1 1.34694
JUNB jun B proto-oncogene 1.34489
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.34372
FGF2 fibroblast growth factor 2 (basic) 1.33081
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.32162
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.32044
GAL galanin/GMAP prepropeptide 1.31746
CCND3 cyclin D3 1.31446
CCND1 cyclin D1 1.31
EDNRB endothelin receptor type B 1.30758
SOD1 superoxide dismutase 1, soluble 1.3039
PLCG1 phospholipase C, gamma 1 1.3039
GSTM1 glutathione S-transferase mu 1 1.30208
CXCL10 chemokine (C-X-C motif) ligand 10 1.29905
NPR1 natriuretic peptide receptor 1 1.29905
GSTP1 glutathione S-transferase pi 1 1.29626
XBP1 X-box binding protein 1 1.29103
ICAM1 intercellular adhesion molecule 1 1.28765
TRIB3 tribbles pseudokinase 3 1.28765
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.28549
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.28425
GAP43 growth associated protein 43 1.28364
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.28364
NFE2L2 nuclear factor, erythroid 2-like 2 1.2744
TIMP2 TIMP metallopeptidase inhibitor 2 1.27193
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.27162
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.26947
CDK5 cyclin-dependent kinase 5 1.26947
MAPK14 mitogen-activated protein kinase 14 1.26856
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.26421
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.26298
MMP9 matrix metallopeptidase 9 1.2596
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.25838
COX5A cytochrome c oxidase subunit Va 1.25776
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.2509
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.24687
PPARG peroxisome proliferator-activated receptor gamma 1.24655
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 1.24307
ADRB2 adrenoceptor beta 2, surface 1.24275
IL4 interleukin 4 1.24181
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.23233
GUCY1B3 guanylate cyclase 1, soluble, beta 3 1.23233
GNAS GNAS complex locus 1.23233
BAG1 BCL2-associated athanogene 1.22566
AVP arginine vasopressin 1.22436
NGF nerve growth factor (beta polypeptide) 1.22371
TJP1 tight junction protein 1 1.22048
GAMT guanidinoacetate N-methyltransferase 1.21567
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.21173
NR2F2 nuclear receptor subfamily 2, group F, member 2 1.20913
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.20913
CALR calreticulin 1.20687
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.20493
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.20295
SOD2 superoxide dismutase 2, mitochondrial 1.19868
COL1A1 collagen, type I, alpha 1 1.19542
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.19412
PTK2 protein tyrosine kinase 2 1.19379
RHOA ras homolog family member A 1.19379
VCAM1 vascular cell adhesion molecule 1 1.19379
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.19179
ADM adrenomedullin 1.19179
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.1908
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.18652
SYP synaptophysin 1.18489
HMOX1 heme oxygenase 1 1.18293
CYCS cytochrome c, somatic 1.18126
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.18126
ESR1 estrogen receptor 1 1.18059
CFLAR CASP8 and FADD-like apoptosis regulator 1.17959
CRH corticotropin releasing hormone 1.17959
PER1 period circadian clock 1 1.17893
GRIK2 glutamate receptor, ionotropic, kainate 2 1.17827
ANGPTL4 angiopoietin-like 4 1.17761
TH tyrosine hydroxylase 1.17728
HSPA1A heat shock 70kDa protein 1A 1.17629
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.17629
TAC1 tachykinin, precursor 1 1.17629
ADCY9 adenylate cyclase 9 1.173
RGS4 regulator of G-protein signaling 4 1.17101
ANXA4 annexin A4 1.16269
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.16269
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.16137
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.15695
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.15593
NUPR1 nuclear protein, transcriptional regulator, 1 1.15593
F3 coagulation factor III (thromboplastin, tissue factor) 1.1529
EIF4E eukaryotic translation initiation factor 4E 1.15223
CCND2 cyclin D2 1.15122
GCLM glutamate-cysteine ligase, modifier subunit 1.15022
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.14989
IGFBP4 insulin-like growth factor binding protein 4 1.14954
MPO myeloperoxidase 1.14747
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.14507
GDNF glial cell derived neurotrophic factor 1.14473
ACTB actin, beta 1.142
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.14166
CPT1A carnitine palmitoyltransferase 1A (liver) 1.1403
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.13724
IGF1R insulin-like growth factor 1 receptor 1.13415
SCNN1A sodium channel, non voltage gated 1 alpha subunit 1.13245
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.13245
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.1294
SCNN1B sodium channel, non voltage gated 1 beta subunit 1.12564
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.1253
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 1.1253
INS insulin 1.1253
EGFR epidermal growth factor receptor 1.12426
MMP2 matrix metallopeptidase 2 1.12288
CRK v-crk avian sarcoma virus CT10 oncogene homolog 1.1129
S100A6 S100 calcium binding protein A6 1.11186
EPAS1 endothelial PAS domain protein 1 1.11186
NOS1 nitric oxide synthase 1 (neuronal) 1.10977
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.10942
E2F3 E2F transcription factor 3 1.10872
GSK3B glycogen synthase kinase 3 beta 1.10838
CREM cAMP responsive element modulator 1.10734
HLA-F major histocompatibility complex, class I, F 1.10388
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.10282
KDR kinase insert domain receptor 1.10282
HLA-B major histocompatibility complex, class I, B 1.10104
IFRD1 interferon-related developmental regulator 1 1.09857
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.09857
NRP1 neuropilin 1 1.09646
RAMP2 receptor (G protein-coupled) activity modifying protein 2 1.0894
EFNA2 ephrin-A2 1.08619
SFTPC surfactant protein C 1.08584
GADD45A growth arrest and DNA-damage-inducible, alpha 1.08549
OXT oxytocin/neurophysin I prepropeptide 1.08442
TK1 thymidine kinase 1, soluble 1.08231
RAMP1 receptor (G protein-coupled) activity modifying protein 1 1.08196
CTGF connective tissue growth factor 1.08019
PDIA3 protein disulfide isomerase family A, member 3 1.07983
BAD BCL2-associated agonist of cell death 1.07269
DHFR dihydrofolate reductase 1.07234
SQLE squalene epoxidase 1.07234
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.07199
CCNT1 cyclin T1 1.07022
APOE apolipoprotein E 1.07022
TRAF2 TNF receptor-associated factor 2 1.06771
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.06625
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.06588
FASLG Fas ligand (TNF superfamily, member 6) 1.06261
PRPF18 pre-mRNA processing factor 18 1.06225
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.06152
TFRC transferrin receptor 1.06008
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.059
SHH sonic hedgehog 1.05828
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.05793
ACTG2 actin, gamma 2, smooth muscle, enteric 1.05793
TFDP1 transcription factor Dp-1 1.05793
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.05423
ELN elastin 1.052
RGS2 regulator of G-protein signaling 2 1.05126
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.04978
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.04831
POSTN periostin, osteoblast specific factor 1.04831
MYOM1 myomesin 1 1.04794
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 1.04794
S100A8 S100 calcium binding protein A8 1.04794
GEM GTP binding protein overexpressed in skeletal muscle 1.04794
PRKCB protein kinase C, beta 1.04757
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.04538
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.04352
BBC3 BCL2 binding component 3 1.04239
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 1.04126
CDK4 cyclin-dependent kinase 4 1.04088
EYA2 EYA transcriptional coactivator and phosphatase 2 1.04088
KNG1 kininogen 1 1.03864
TNNI3 troponin I type 3 (cardiac) 1.03827
ANXA5 annexin A5 1.03715
PPP1R12A protein phosphatase 1, regulatory subunit 12A 1.03604
SMAD4 SMAD family member 4 1.03567
ACOT2 acyl-CoA thioesterase 2 1.03271
HSPB2 heat shock 27kDa protein 2 1.02858
KMT2E lysine (K)-specific methyltransferase 2E 1.02746
AGTR2 angiotensin II receptor, type 2 1.02708
RRM2 ribonucleotide reductase M2 1.02671
EFNB3 ephrin-B3 1.02151
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 1.02114
DUT deoxyuridine triphosphatase 1.02077
CCNA2 cyclin A2 1.01966
KIAA1467 KIAA1467 1.01928
COL3A1 collagen, type III, alpha 1 1.01814
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.01814
GPX3 glutathione peroxidase 3 1.01663
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 1.01587
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.01587
OPRM1 opioid receptor, mu 1 1.01512
MAGED1 melanoma antigen family D1 1.01512
HSPA1B heat shock 70kDa protein 1B 1.01512
DCAF8 DDB1 and CUL4 associated factor 8 1.01512
TGFB2 transforming growth factor, beta 2 1.01474
BAK1 BCL2-antagonist/killer 1 1.01361
ACTA1 actin, alpha 1, skeletal muscle 1.01249
TXNRD1 thioredoxin reductase 1 1.01212
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.01212
DRD2 dopamine receptor D2 1.01212
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.01174
MAOA monoamine oxidase A 1.01174
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.01099