Fanconi Anemia pathway Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
Description Interstrand cross links (ICL) of DNA can be induced by both endogenous and exogenous ligands. ICL if not repaired will lead to cell death. ICL repair pathway, also known as Fanconi anemia pathway is the cellular response to this type of DNA damage. (Pathway Ontology, PW_0001065)
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-6783310
Similar Terms
Downloads & Tools

Genes

22 proteins participating in the Fanconi Anemia pathway pathway from the Reactome Pathways dataset.

Symbol Name
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
FANCA Fanconi anemia, complementation group A
FANCB Fanconi anemia, complementation group B
FANCC Fanconi anemia, complementation group C
FANCD2 Fanconi anemia, complementation group D2
FANCE Fanconi anemia, complementation group E
FANCF Fanconi anemia, complementation group F
FANCG Fanconi anemia, complementation group G
FANCI Fanconi anemia, complementation group I
FANCL Fanconi anemia, complementation group L
FANCM Fanconi anemia, complementation group M
PALB2 partner and localizer of BRCA2
RPS27A ribosomal protein S27a
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2T ubiquitin-conjugating enzyme E2T
USP1 ubiquitin specific peptidase 1
ZBTB32 zinc finger and BTB domain containing 32