Familial hypophosphataemic rickets_Renal Tissue_GSE868 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE868
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Genes

600 genes differentially expressed during Familial hypophosphataemic rickets_Renal Tissue_GSE868 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
PTPRF protein tyrosine phosphatase, receptor type, F 4.38254
BEX4 brain expressed, X-linked 4 3.50814
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 3.36574
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 3.31802
HPCAL1 hippocalcin-like 1 3.26638
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 3.19753
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 3.16107
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 3.11434
NLK nemo-like kinase 3.07601
BLNK B-cell linker 3.05808
PLS3 plastin 3 2.99829
AOAH acyloxyacyl hydrolase (neutrophil) 2.98773
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 2.93755
RHOD ras homolog family member D 2.92275
PTDSS1 phosphatidylserine synthase 1 2.91682
PLSCR1 phospholipid scramblase 1 2.89944
IARS isoleucyl-tRNA synthetase 2.88403
TMPRSS2 transmembrane protease, serine 2 2.75595
TUBA1C tubulin, alpha 1c 2.737
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 2.68996
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 2.6605
ERMP1 endoplasmic reticulum metallopeptidase 1 2.6492
TACSTD2 tumor-associated calcium signal transducer 2 2.63435
ERRFI1 ERBB receptor feedback inhibitor 1 2.61868
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A 2.58836
SLC4A3 solute carrier family 4 (anion exchanger), member 3 2.58171
MFGE8 milk fat globule-EGF factor 8 protein 2.55802
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 2.5439
C5ORF30 chromosome 5 open reading frame 30 2.54081
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 2.53238
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 2.53158
FAM69B family with sequence similarity 69, member B 2.50869
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 2.45173
RNASE4 ribonuclease, RNase A family, 4 2.4487
GIMAP4 GTPase, IMAP family member 4 2.44747
TMEM205 transmembrane protein 205 2.43317
RCC1 regulator of chromosome condensation 1 2.4318
NFE2L2 nuclear factor, erythroid 2-like 2 2.42865
CD99L2 CD99 molecule-like 2 2.42136
FAM192A family with sequence similarity 192, member A 2.41231
PSAT1 phosphoserine aminotransferase 1 2.41209
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 2.40689
RAMP2 receptor (G protein-coupled) activity modifying protein 2 2.39493
GLRX glutaredoxin (thioltransferase) 2.38021
FKBP10 FK506 binding protein 10, 65 kDa 2.36296
KITLG KIT ligand 2.36283
MFSD4 major facilitator superfamily domain containing 4 2.36125
COPS5 COP9 signalosome subunit 5 2.34621
PKM pyruvate kinase, muscle 2.3433
DPP7 dipeptidyl-peptidase 7 2.33853
ANXA4 annexin A4 2.33473
ANXA6 annexin A6 2.31402
WBP5 WW domain binding protein 5 2.29677
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 2.27306
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 2.27141
ACTN1 actinin, alpha 1 2.24758
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 2.2445
IER3 immediate early response 3 2.2341
PROM1 prominin 1 2.22197
PRKD1 protein kinase D1 2.21658
ANG angiogenin, ribonuclease, RNase A family, 5 2.21236
UBA1 ubiquitin-like modifier activating enzyme 1 2.20961
CDC26 cell division cycle 26 2.20594
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 2.20092
NAE1 NEDD8 activating enzyme E1 subunit 1 2.20055
SPRED2 sprouty-related, EVH1 domain containing 2 2.19578
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 2.195
DAP death-associated protein 2.19289
MOB1A MOB kinase activator 1A 2.19153
RBMS1 RNA binding motif, single stranded interacting protein 1 2.17213
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 2.16635
COPB1 coatomer protein complex, subunit beta 1 2.16482
ACTG1 actin gamma 1 2.16336
STX4 syntaxin 4 2.16001
PROS1 protein S (alpha) 2.15899
VMP1 vacuole membrane protein 1 2.15744
SOX13 SRY (sex determining region Y)-box 13 2.14705
TUBA1A tubulin, alpha 1a 2.13586
CAPN10 calpain 10 2.13011
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 2.12511
ITPKB inositol-trisphosphate 3-kinase B 2.11355
PPP6R3 protein phosphatase 6, regulatory subunit 3 2.10754
STX7 syntaxin 7 2.10432
USO1 USO1 vesicle transport factor 2.10092
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 2.09474
CDO1 cysteine dioxygenase type 1 2.08722
RPUSD4 RNA pseudouridylate synthase domain containing 4 2.08544
PTP4A2 protein tyrosine phosphatase type IVA, member 2 2.0838
LAMP1 lysosomal-associated membrane protein 1 2.08263
HLA-A major histocompatibility complex, class I, A 2.07733
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 2.05599
NCKAP1 NCK-associated protein 1 2.05472
PDLIM4 PDZ and LIM domain 4 2.05163
FBXO9 F-box protein 9 2.05049
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 2.04806
BECN1 beclin 1, autophagy related 2.0296
COLGALT1 collagen beta(1-O)galactosyltransferase 1 2.02043
NQO1 NAD(P)H dehydrogenase, quinone 1 2.01895
FGF9 fibroblast growth factor 9 2.01883
FKBP9 FK506 binding protein 9, 63 kDa 2.01742
NF2 neurofibromin 2 (merlin) 2.01678
YLPM1 YLP motif containing 1 2.01623
CLTC clathrin, heavy chain (Hc) 2.015
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 2.01193
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 2.01037
COPA coatomer protein complex, subunit alpha 2.00407
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 2.00394
SMAD2 SMAD family member 2 2.00305
LAPTM4B lysosomal protein transmembrane 4 beta 2.00182
PTS 6-pyruvoyltetrahydropterin synthase 1.99311
MRFAP1 Morf4 family associated protein 1 1.98159
ABHD16A abhydrolase domain containing 16A 1.96685
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant 1.96645
PFKP phosphofructokinase, platelet 1.96237
RAB25 RAB25, member RAS oncogene family 1.95594
MDFIC MyoD family inhibitor domain containing 1.94785
EFTUD1 elongation factor Tu GTP binding domain containing 1 1.9453
DSCR3 Down syndrome critical region 3 1.9437
AIP aryl hydrocarbon receptor interacting protein 1.94243
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 1.92886
ELP3 elongator acetyltransferase complex subunit 3 1.9214
IPO7 importin 7 1.92055
PLBD1 phospholipase B domain containing 1 1.91598
MBTPS1 membrane-bound transcription factor peptidase, site 1 1.90963
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 1.90253
WIZ widely interspaced zinc finger motifs 1.90154
VEGFB vascular endothelial growth factor B 1.89779
STXBP2 syntaxin binding protein 2 1.89542
PLAC8 placenta-specific 8 1.87998
RXRA retinoid X receptor, alpha 1.87847
TXK TXK tyrosine kinase 1.8745
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 1.87381
COMMD7 COMM domain containing 7 1.86056
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 1.85731
SPATA13 spermatogenesis associated 13 1.85163
MTM1 myotubularin 1 1.85148
PAIP2B poly(A) binding protein interacting protein 2B 1.85054
UNC119B unc-119 homolog B (C. elegans) 1.84841
CIRH1A cirrhosis, autosomal recessive 1A (cirhin) 1.84833
CDC42SE1 CDC42 small effector 1 1.84594
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) 1.84564
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa 1.83782
XPC xeroderma pigmentosum, complementation group C 1.83766
RNF149 ring finger protein 149 1.83626
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 1.83257
C9ORF72 chromosome 9 open reading frame 72 1.829
LENG9 leukocyte receptor cluster (LRC) member 9 1.82843
VTA1 vesicle (multivesicular body) trafficking 1 1.82612
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 1.82403
PELO pelota homolog (Drosophila) 1.82209
SCAMP1 secretory carrier membrane protein 1 1.82198
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 1.82104
AP3D1 adaptor-related protein complex 3, delta 1 subunit 1.81884
SNIP1 Smad nuclear interacting protein 1 1.81739
NUMB numb homolog (Drosophila) 1.81555
SALL3 spalt-like transcription factor 3 1.81341
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 1.81153
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 1.80573
HMOX1 heme oxygenase 1 1.8049
SSBP2 single-stranded DNA binding protein 2 1.80229
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 1.8015
ACSL4 acyl-CoA synthetase long-chain family member 4 1.79913
ZNF207 zinc finger protein 207 1.79629
NBN nibrin 1.78638
CNOT4 CCR4-NOT transcription complex, subunit 4 1.78296
RTN4 reticulon 4 1.78109
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 1.77841
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.77805
RPIA ribose 5-phosphate isomerase A 1.77261
NCOR1 nuclear receptor corepressor 1 1.76437
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.75937
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.75443
KIAA1161 KIAA1161 1.75185
NRP1 neuropilin 1 1.74762
CD59 CD59 molecule, complement regulatory protein 1.7456
JAGN1 jagunal homolog 1 (Drosophila) 1.74536
CXXC5 CXXC finger protein 5 1.74532
MID1IP1 MID1 interacting protein 1 1.745
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 1.74429
G6PC glucose-6-phosphatase, catalytic subunit 1.74172
RELL1 RELT-like 1 1.73674
MED20 mediator complex subunit 20 1.73504
LYN LYN proto-oncogene, Src family tyrosine kinase 1.73467
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 1.73145
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 1.72875
ETV1 ets variant 1 1.72291
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.7224
MTIF2 mitochondrial translational initiation factor 2 1.7188
PRKCD protein kinase C, delta 1.70038
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 1.69854
MVP major vault protein 1.69791
PTDSS2 phosphatidylserine synthase 2 1.6929
ATP13A3 ATPase type 13A3 1.69111
BTG2 BTG family, member 2 1.68661
SCG5 secretogranin V 1.68273
PPIA peptidylprolyl isomerase A (cyclophilin A) 1.67726
CLDND1 claudin domain containing 1 1.66883
MAN2A1 mannosidase, alpha, class 2A, member 1 1.66817
MTSS1L metastasis suppressor 1-like 1.66539
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 1.66484
CARM1 coactivator-associated arginine methyltransferase 1 1.66217
CTSC cathepsin C 1.66073
CREM cAMP responsive element modulator 1.65845
WDR26 WD repeat domain 26 1.65736
XBP1 X-box binding protein 1 1.65658
FJX1 four jointed box 1 (Drosophila) 1.65549
USP3 ubiquitin specific peptidase 3 1.65412
AP1AR adaptor-related protein complex 1 associated regulatory protein 1.64578
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 1.64528
ELF4 E74-like factor 4 (ets domain transcription factor) 1.64519
PRKCA protein kinase C, alpha 1.64442
HOXB2 homeobox B2 1.64315
ADPRH ADP-ribosylarginine hydrolase 1.6394
FAM13B family with sequence similarity 13, member B 1.63758
ABLIM1 actin binding LIM protein 1 1.63642
TTR transthyretin 1.63512
TAPBP TAP binding protein (tapasin) 1.63353
ARL4C ADP-ribosylation factor-like 4C 1.62511
RASA1 RAS p21 protein activator (GTPase activating protein) 1 1.62154
NSUN4 NOP2/Sun domain family, member 4 1.61836
EPB41L2 erythrocyte membrane protein band 4.1-like 2 1.61758
TRIM21 tripartite motif containing 21 1.61702
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 1.61417
TCOF1 Treacher Collins-Franceschetti syndrome 1 1.61366
INPP5J inositol polyphosphate-5-phosphatase J 1.60864
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 1.60815
PCID2 PCI domain containing 2 1.60803
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 1.60561
NEK6 NIMA-related kinase 6 1.59332
SRM spermidine synthase 1.59289
RALB v-ral simian leukemia viral oncogene homolog B 1.59267
PRKCE protein kinase C, epsilon 1.5921
PTK2B protein tyrosine kinase 2 beta 1.59203
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 1.58837
RNASEK ribonuclease, RNase K 1.58757
GRK5 G protein-coupled receptor kinase 5 1.58637
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.58622
CAPN6 calpain 6 1.58247
KLF7 Kruppel-like factor 7 (ubiquitous) 1.57446
HOXA5 homeobox A5 1.57393
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.57045
ELAVL1 ELAV like RNA binding protein 1 1.56655
THBD thrombomodulin 1.56526
BCL2 B-cell CLL/lymphoma 2 1.56399
KRTCAP2 keratinocyte associated protein 2 1.55651
FUBP1 far upstream element (FUSE) binding protein 1 1.55486
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 1.55294
BCAP31 B-cell receptor-associated protein 31 1.55172
ECI1 enoyl-CoA delta isomerase 1 1.55053
PITPNA phosphatidylinositol transfer protein, alpha 1.54247
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 1.53832
C1QC complement component 1, q subcomponent, C chain 1.52966
RAB5A RAB5A, member RAS oncogene family 1.51795
INTS4 integrator complex subunit 4 1.51438
EIF3A eukaryotic translation initiation factor 3, subunit A 1.51395
PRUNE prune exopolyphosphatase 1.5114
MAP2K6 mitogen-activated protein kinase kinase 6 1.51126
GAS6 growth arrest-specific 6 1.51046
CYB561 cytochrome b561 1.50979
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.50693
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 1.50627
HOXB6 homeobox B6 1.50212
INHA inhibin, alpha 1.50174
PNPT1 polyribonucleotide nucleotidyltransferase 1 1.50157
NPTX2 neuronal pentraxin II 1.49771
EIF1AX eukaryotic translation initiation factor 1A, X-linked 1.493
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.49285
SLC35E1 solute carrier family 35, member E1 1.49025
TSNAX translin-associated factor X 1.4895
TSPAN7 tetraspanin 7 1.48891
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 1.48835
AZGP1 alpha-2-glycoprotein 1, zinc-binding 1.48631
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 1.486
HES1 hes family bHLH transcription factor 1 1.48145
SREBF1 sterol regulatory element binding transcription factor 1 1.47785
SCARB1 scavenger receptor class B, member 1 1.47707
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.47486
SIM1 single-minded family bHLH transcription factor 1 1.47333
MECP2 methyl CpG binding protein 2 1.47186
LPCAT3 lysophosphatidylcholine acyltransferase 3 1.47165
GINM1 glycoprotein integral membrane 1 1.47051
ZFP36 ZFP36 ring finger protein 1.47025
BET1L Bet1 golgi vesicular membrane trafficking protein-like 1.46842
SMYD5 SMYD family member 5 1.46699
PRPS1 phosphoribosyl pyrophosphate synthetase 1 1.46366
ALDOC aldolase C, fructose-bisphosphate 1.46162
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 1.45863
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 1.45811
UBQLN2 ubiquilin 2 1.4567
PLRG1 pleiotropic regulator 1 1.4562
RRAD Ras-related associated with diabetes 1.45381
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase 1.44684
NUCB1 nucleobindin 1 1.44558
FMNL3 formin-like 3 1.44489
KRT31 keratin 31, type I 1.44441
ADGRL1 adhesion G protein-coupled receptor L1 1.44216
TPRG1L tumor protein p63 regulated 1-like 1.43861
DAZAP2 DAZ associated protein 2 1.43846
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 1.43111
SURF1 surfeit 1 1.4308

decreased expression

Symbol Name Standardized Value
KL klotho -3.71809
CA14 carbonic anhydrase XIV -3.2555
HAGH hydroxyacylglutathione hydrolase -3.08493
NDRG1 N-myc downstream regulated 1 -2.99283
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -2.95284
HBS1L HBS1-like translational GTPase -2.90962
COQ5 coenzyme Q5 homolog, methyltransferase (S. cerevisiae) -2.86611
C20ORF24 chromosome 20 open reading frame 24 -2.84739
LARS leucyl-tRNA synthetase -2.83706
ACOT13 acyl-CoA thioesterase 13 -2.78408
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 -2.7774
PDZK1 PDZ domain containing 1 -2.74271
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -2.67458
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa -2.65806
ABHD5 abhydrolase domain containing 5 -2.65606
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 -2.64071
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase -2.63951
XPR1 xenotropic and polytropic retrovirus receptor 1 -2.6358
ANKRD33B ankyrin repeat domain 33B -2.57282
SLC26A1 solute carrier family 26 (anion exchanger), member 1 -2.52409
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa -2.50774
IMPAD1 inositol monophosphatase domain containing 1 -2.50717
RPL7A ribosomal protein L7a -2.48544
AFM afamin -2.48143
CD63 CD63 molecule -2.47945
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 -2.47874
APP amyloid beta (A4) precursor protein -2.47765
CDAN1 codanin 1 -2.46444
MGEA5 meningioma expressed antigen 5 (hyaluronidase) -2.45472
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) -2.44576
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) -2.40928
LAMP2 lysosomal-associated membrane protein 2 -2.4043
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -2.39166
IRX3 iroquois homeobox 3 -2.38566
DNASE1 deoxyribonuclease I -2.32754
UBQLN4 ubiquilin 4 -2.32374
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 -2.29645
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) -2.28823
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 -2.2498
CLTB clathrin, light chain B -2.22616
SFXN1 sideroflexin 1 -2.21343
SLC35B1 solute carrier family 35, member B1 -2.21058
NFS1 NFS1 cysteine desulfurase -2.20582
PTCD3 pentatricopeptide repeat domain 3 -2.2044
ANPEP alanyl (membrane) aminopeptidase -2.17457
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -2.16764
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 -2.1648
MAN1A1 mannosidase, alpha, class 1A, member 1 -2.14706
LIFR leukemia inhibitory factor receptor alpha -2.13761
FAM107B family with sequence similarity 107, member B -2.13075
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa -2.11677
ANAPC11 anaphase promoting complex subunit 11 -2.11645
MRPL18 mitochondrial ribosomal protein L18 -2.11394
MYEOV2 myeloma overexpressed 2 -2.10009
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.08416
CA2 carbonic anhydrase II -2.0806
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.06705
CLCN3 chloride channel, voltage-sensitive 3 -2.05716
CSNK2A2 casein kinase 2, alpha prime polypeptide -2.05557
CNOT1 CCR4-NOT transcription complex, subunit 1 -2.03881
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) -2.0378
SQLE squalene epoxidase -2.03516
ANKRD13C ankyrin repeat domain 13C -2.02898
PIGA phosphatidylinositol glycan anchor biosynthesis, class A -2.02706
ADIPOR2 adiponectin receptor 2 -2.02153
PTTG1IP pituitary tumor-transforming 1 interacting protein -2.01492
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -2.01184
GATAD2A GATA zinc finger domain containing 2A -2.00655
ALDOB aldolase B, fructose-bisphosphate -2.00304
PICK1 protein interacting with PRKCA 1 -1.98986
COL4A2 collagen, type IV, alpha 2 -1.98856
IL17RA interleukin 17 receptor A -1.97413
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 -1.96947
TFCP2 transcription factor CP2 -1.96474
POR P450 (cytochrome) oxidoreductase -1.96232
LPIN1 lipin 1 -1.96204
MPV17 MpV17 mitochondrial inner membrane protein -1.95802
CMIP c-Maf inducing protein -1.95713
RNASEH2B ribonuclease H2, subunit B -1.95625
RAB5C RAB5C, member RAS oncogene family -1.95567
KIF1C kinesin family member 1C -1.95319
PTPRB protein tyrosine phosphatase, receptor type, B -1.95041
ZDHHC16 zinc finger, DHHC-type containing 16 -1.93804
PDGFA platelet-derived growth factor alpha polypeptide -1.93779
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -1.93393
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -1.92848
RARS2 arginyl-tRNA synthetase 2, mitochondrial -1.89325
NME6 NME/NM23 nucleoside diphosphate kinase 6 -1.88209
STOML2 stomatin (EPB72)-like 2 -1.87913
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa -1.87889
C5ORF15 chromosome 5 open reading frame 15 -1.87662
SARDH sarcosine dehydrogenase -1.87656
COPS4 COP9 signalosome subunit 4 -1.86837
RWDD4 RWD domain containing 4 -1.86257
WDR1 WD repeat domain 1 -1.86004
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -1.84662
MAPT microtubule-associated protein tau -1.83943
ARL6 ADP-ribosylation factor-like 6 -1.8333
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 -1.82903
LRRC59 leucine rich repeat containing 59 -1.82501
MXI1 MAX interactor 1, dimerization protein -1.8229
KIF22 kinesin family member 22 -1.81053
INPP5K inositol polyphosphate-5-phosphatase K -1.8049
SUSD4 sushi domain containing 4 -1.7898
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -1.78891
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -1.78776
PQLC1 PQ loop repeat containing 1 -1.78234
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -1.78019
MOCS2 molybdenum cofactor synthesis 2 -1.77716
ZNF639 zinc finger protein 639 -1.77371
SCAMP2 secretory carrier membrane protein 2 -1.77323
TMEM106C transmembrane protein 106C -1.76245
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -1.76059
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 -1.75738
TADA1 transcriptional adaptor 1 -1.75496
MFSD1 major facilitator superfamily domain containing 1 -1.75322
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -1.74934
MARCH5 membrane-associated ring finger (C3HC4) 5 -1.7445
ZNRD1 zinc ribbon domain containing 1 -1.74341
RPS26 ribosomal protein S26 -1.72689
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa -1.71562
FIGF c-fos induced growth factor (vascular endothelial growth factor D) -1.71468
MRPL21 mitochondrial ribosomal protein L21 -1.71107
TERF2 telomeric repeat binding factor 2 -1.71036
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase -1.70235
EPN1 epsin 1 -1.70058
PURA purine-rich element binding protein A -1.69619
WDR81 WD repeat domain 81 -1.69527
CD320 CD320 molecule -1.69476
SPA17 sperm autoantigenic protein 17 -1.6815
RP9 retinitis pigmentosa 9 (autosomal dominant) -1.67842
TSFM Ts translation elongation factor, mitochondrial -1.67117
FYTTD1 forty-two-three domain containing 1 -1.67093
C4ORF27 chromosome 4 open reading frame 27 -1.66704
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -1.66461
CDT1 chromatin licensing and DNA replication factor 1 -1.66456
HIGD2A HIG1 hypoxia inducible domain family, member 2A -1.66185
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -1.66065
F3 coagulation factor III (thromboplastin, tissue factor) -1.65297
AADAC arylacetamide deacetylase -1.65012
SORD sorbitol dehydrogenase -1.63552
PAH phenylalanine hydroxylase -1.63185
ETHE1 ethylmalonic encephalopathy 1 -1.62135
YBX1 Y box binding protein 1 -1.61573
JUND jun D proto-oncogene -1.6139
AMZ2 archaelysin family metallopeptidase 2 -1.61322
MCFD2 multiple coagulation factor deficiency 2 -1.60912
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -1.60658
USP6NL USP6 N-terminal like -1.60235
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled -1.60223
AMMECR1L AMMECR1-like -1.59576
ABHD14A abhydrolase domain containing 14A -1.59388
CALB1 calbindin 1, 28kDa -1.59273
H2AFZ H2A histone family, member Z -1.59097
RAB4A RAB4A, member RAS oncogene family -1.5902
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -1.58974
CCNDBP1 cyclin D-type binding-protein 1 -1.58398
GLP2R glucagon-like peptide 2 receptor -1.57863
N6AMT2 N-6 adenine-specific DNA methyltransferase 2 (putative) -1.57599
PRDX1 peroxiredoxin 1 -1.57094
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -1.56868
GFM1 G elongation factor, mitochondrial 1 -1.56582
SLC38A10 solute carrier family 38, member 10 -1.55671
ELOVL1 ELOVL fatty acid elongase 1 -1.5535
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -1.55023
HINT1 histidine triad nucleotide binding protein 1 -1.54754
PABPC1 poly(A) binding protein, cytoplasmic 1 -1.54681
TXNRD2 thioredoxin reductase 2 -1.54575
FAM171A1 family with sequence similarity 171, member A1 -1.54557
BTF3 basic transcription factor 3 -1.54381
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) -1.54244
LOC102288414 -1.54103
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog -1.54032
CA4 carbonic anhydrase IV -1.53835
NPY neuropeptide Y -1.53829
NEURL4 neuralized E3 ubiquitin protein ligase 4 -1.53626
TEF thyrotrophic embryonic factor -1.53483
PALM paralemmin -1.53123
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -1.52551
UNC119 unc-119 homolog (C. elegans) -1.52343
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -1.52238
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) -1.51536
TRAK1 trafficking protein, kinesin binding 1 -1.51439
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -1.51383
ESD esterase D -1.51342
PPIF peptidylprolyl isomerase F -1.51248
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -1.51077
B9D1 B9 protein domain 1 -1.50816
CLRN3 clarin 3 -1.50482
DUSP2 dual specificity phosphatase 2 -1.50373
GCSH glycine cleavage system protein H (aminomethyl carrier) -1.49674
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -1.4954
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -1.49162
CYFIP2 cytoplasmic FMR1 interacting protein 2 -1.48726
VLDLR very low density lipoprotein receptor -1.48635
COL4A1 collagen, type IV, alpha 1 -1.48487
COPS3 COP9 signalosome subunit 3 -1.47957
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -1.47792
DTYMK deoxythymidylate kinase (thymidylate kinase) -1.47607
C5ORF51 chromosome 5 open reading frame 51 -1.47563
DLD dihydrolipoamide dehydrogenase -1.47414
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 -1.46757
FAM20C family with sequence similarity 20, member C -1.46722
RPL6 ribosomal protein L6 -1.46657
SRCAP Snf2-related CREBBP activator protein -1.46541
RNF8 ring finger protein 8, E3 ubiquitin protein ligase -1.45987
PVALB parvalbumin -1.45771
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -1.45133
COL8A1 collagen, type VIII, alpha 1 -1.44784
SUN2 Sad1 and UNC84 domain containing 2 -1.44762
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10 -1.44757
NPNT nephronectin -1.44447
GNL1 guanine nucleotide binding protein-like 1 -1.43467
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -1.43346
DERL1 derlin 1 -1.43152
CCT4 chaperonin containing TCP1, subunit 4 (delta) -1.43133
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -1.4295
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone -1.42742
WWP2 WW domain containing E3 ubiquitin protein ligase 2 -1.4258
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) -1.42534
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) -1.42447
INPP1 inositol polyphosphate-1-phosphatase -1.42257
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) -1.42187
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -1.42056
EIF4E2 eukaryotic translation initiation factor 4E family member 2 -1.41929
METTL9 methyltransferase like 9 -1.41902
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -1.41877
RFC5 replication factor C (activator 1) 5, 36.5kDa -1.41673
CHPT1 choline phosphotransferase 1 -1.41533
EPS8 epidermal growth factor receptor pathway substrate 8 -1.40915
UBE2R2 ubiquitin-conjugating enzyme E2R 2 -1.40771
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -1.40765
ADCY9 adenylate cyclase 9 -1.40186
IL10RB interleukin 10 receptor, beta -1.40067
GAS2 growth arrest-specific 2 -1.40037
MTX2 metaxin 2 -1.39988
IFT172 intraflagellar transport 172 -1.39493
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -1.39361
TGDS TDP-glucose 4,6-dehydratase -1.38996
MRPS26 mitochondrial ribosomal protein S26 -1.38821
NPHP1 nephronophthisis 1 (juvenile) -1.38798
PDHB pyruvate dehydrogenase (lipoamide) beta -1.38451
ACOT9 acyl-CoA thioesterase 9 -1.37719
MBD4 methyl-CpG binding domain protein 4 -1.37274
LRP2 low density lipoprotein receptor-related protein 2 -1.37201
EXT1 exostosin glycosyltransferase 1 -1.3697
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -1.36967
CCNG1 cyclin G1 -1.36789
C3ORF58 chromosome 3 open reading frame 58 -1.36453
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -1.36418
LIPA lipase A, lysosomal acid, cholesterol esterase -1.36386
MRPL43 mitochondrial ribosomal protein L43 -1.36032
EFNB1 ephrin-B1 -1.35125
DCN decorin -1.34538
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -1.34012
FHL1 four and a half LIM domains 1 -1.33983
ERCC5 excision repair cross-complementation group 5 -1.33379
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5 -1.33094
LDHA lactate dehydrogenase A -1.33005
NDN necdin, melanoma antigen (MAGE) family member -1.32674
UBE2K ubiquitin-conjugating enzyme E2K -1.32433
GRB7 growth factor receptor-bound protein 7 -1.32318
SDHAF1 succinate dehydrogenase complex assembly factor 1 -1.32236
MIOX myo-inositol oxygenase -1.31286
ARL2BP ADP-ribosylation factor-like 2 binding protein -1.31074
GUCA2B guanylate cyclase activator 2B (uroguanylin) -1.30756
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -1.30751
MRPL30 mitochondrial ribosomal protein L30 -1.30646
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 -1.30061
PDPK1 3-phosphoinositide dependent protein kinase 1 -1.30059
MDH2 malate dehydrogenase 2, NAD (mitochondrial) -1.29998
LONP2 lon peptidase 2, peroxisomal -1.29876
TTC7B tetratricopeptide repeat domain 7B -1.29244
RAB3IP RAB3A interacting protein -1.29066
ACP1 acid phosphatase 1, soluble -1.28865
APRT adenine phosphoribosyltransferase -1.28553
PAIP2 poly(A) binding protein interacting protein 2 -1.28368
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -1.28168
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -1.28062
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) -1.27833
ZMAT3 zinc finger, matrin-type 3 -1.27666
PCYT1A phosphate cytidylyltransferase 1, choline, alpha -1.27226
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -1.27059
SERP1 stress-associated endoplasmic reticulum protein 1 -1.26811
JKAMP JNK1/MAPK8-associated membrane protein -1.26352
TXNDC17 thioredoxin domain containing 17 -1.25431
TDP2 tyrosyl-DNA phosphodiesterase 2 -1.25362
HSPB2 heat shock 27kDa protein 2 -1.25243
PCBP2 poly(rC) binding protein 2 -1.2499
RAD50 RAD50 homolog (S. cerevisiae) -1.24798
DAO D-amino-acid oxidase -1.24695
HELB helicase (DNA) B -1.24692
SIVA1 SIVA1, apoptosis-inducing factor -1.24599
LMO1 LIM domain only 1 (rhombotin 1) -1.24488
GSG2 germ cell associated 2 (haspin) -1.24255
PARL presenilin associated, rhomboid-like -1.23922
SELENBP1 selenium binding protein 1 -1.23869
CCBL2 cysteine conjugate-beta lyase 2 -1.23838
PCYOX1 prenylcysteine oxidase 1 -1.23812
GPC4 glypican 4 -1.23375