F0447-0125-6401 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the F0447-0125-6401 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APC adenomatous polyposis coli
ARL4D ADP-ribosylation factor-like 4D
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C10ORF10 chromosome 10 open reading frame 10
C17ORF59 chromosome 17 open reading frame 59
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACFD1 calcium channel flower domain containing 1
CADM3 cell adhesion molecule 3
CADM4 cell adhesion molecule 4
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CBS cystathionine-beta-synthase
CCNT2 cyclin T2
CDKL3 cyclin-dependent kinase-like 3
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDRT1 CMT1A duplicated region transcript 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CYLD cylindromatosis (turban tumor syndrome)
DDN dendrin
DLG1 discs, large homolog 1 (Drosophila)
DLX2 distal-less homeobox 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EFR3B EFR3 homolog B (S. cerevisiae)
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
FAM46C family with sequence similarity 46, member C
FGFR4 fibroblast growth factor receptor 4
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
FZD1 frizzled class receptor 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAREM GRB2 associated, regulator of MAPK1
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
HOXB2 homeobox B2
HOXC11 homeobox C11
ICAM1 intercellular adhesion molecule 1
ITGA10 integrin, alpha 10
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
JUND jun D proto-oncogene
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KLF6 Kruppel-like factor 6
KLHL25 kelch-like family member 25
KRT24 keratin 24, type I
KRT86 keratin 86, type II
KSR1 kinase suppressor of ras 1
LINS lines homolog (Drosophila)
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MED16 mediator complex subunit 16
MIR22HG MIR22 host gene
MMP13 matrix metallopeptidase 13
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYH14 myosin, heavy chain 14, non-muscle
MYOZ1 myozenin 1
NEU3 sialidase 3 (membrane sialidase)
NMT2 N-myristoyltransferase 2
NOP14-AS1 NOP14 antisense RNA 1
NPR3 natriuretic peptide receptor 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRF1 nuclear respiratory factor 1
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OSGIN1 oxidative stress induced growth inhibitor 1
PAWR PRKC, apoptosis, WT1, regulator
PDCD2 programmed cell death 2
PILRA paired immunoglobin-like type 2 receptor alpha
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POMT2 protein-O-mannosyltransferase 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PTPRE protein tyrosine phosphatase, receptor type, E
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RPAIN RPA interacting protein
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD6 SMAD family member 6
SPN sialophorin
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SRSF1 serine/arginine-rich splicing factor 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TLN2 talin 2
TMEM183A transmembrane protein 183A
TPST2 tyrosylprotein sulfotransferase 2
TRIL TLR4 interactor with leucine-rich repeats
TRIM16 tripartite motif containing 16
TTLL7 tubulin tyrosine ligase-like family member 7
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VN1R1 vomeronasal 1 receptor 1
YIPF2 Yip1 domain family, member 2
ZNF510 zinc finger protein 510
ZSCAN31 zinc finger and SCAN domain containing 31

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACSL5 acyl-CoA synthetase long-chain family member 5
AMT aminomethyltransferase
ARL14 ADP-ribosylation factor-like 14
ARL15 ADP-ribosylation factor-like 15
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
C16ORF45 chromosome 16 open reading frame 45
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CCNO cyclin O
CD34 CD34 molecule
CGREF1 cell growth regulator with EF-hand domain 1
CLCA1 chloride channel accessory 1
CSDC2 cold shock domain containing C2, RNA binding
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DCSTAMP dendrocyte expressed seven transmembrane protein
DIAPH2-AS1 DIAPH2 antisense RNA 1
DISC1 disrupted in schizophrenia 1
DSCAM Down syndrome cell adhesion molecule
ECEL1 endothelin converting enzyme-like 1
ERC2-IT1 ERC2 intronic transcript 1
ERN1 endoplasmic reticulum to nucleus signaling 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV2 ets variant 2
EYA3 EYA transcriptional coactivator and phosphatase 3
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FLJ22184
FLT4 fms-related tyrosine kinase 4
FURIN furin (paired basic amino acid cleaving enzyme)
GRB7 growth factor receptor-bound protein 7
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HAS2 hyaluronan synthase 2
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HGFAC HGF activator
HIST1H2AL histone cluster 1, H2al
HIST1H3A histone cluster 1, H3a
HIST1H3C histone cluster 1, H3c
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LOC100287590 uncharacterized LOC100287590
LPAR6 lysophosphatidic acid receptor 6
LY6G6E lymphocyte antigen 6 complex, locus G6E (pseudogene)
MATN3 matrilin 3
MN1 meningioma (disrupted in balanced translocation) 1
MOXD1 monooxygenase, DBH-like 1
MPZ myelin protein zero
MVD mevalonate (diphospho) decarboxylase
MYEF2 myelin expression factor 2
NGB neuroglobin
PCDH12 protocadherin 12
PKD2L1 polycystic kidney disease 2-like 1
PLA1A phospholipase A1 member A
PPIAL4A peptidylprolyl isomerase A (cyclophilin A)-like 4A
PRDM14 PR domain containing 14
PRODH2 proline dehydrogenase (oxidase) 2
PROM1 prominin 1
PROX1 prospero homeobox 1
PRR3 proline rich 3
PTPRS protein tyrosine phosphatase, receptor type, S
RAB30 RAB30, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RHCG Rh family, C glycoprotein
SCN10A sodium channel, voltage gated, type X alpha subunit
SDC3 syndecan 3
SDS serine dehydratase
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SH3D21 SH3 domain containing 21
SLC17A2 solute carrier family 17, member 2
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
SMO smoothened, frizzled class receptor
SOSTDC1 sclerostin domain containing 1
SP4 Sp4 transcription factor
SPACA1 sperm acrosome associated 1
SPTBN5 spectrin, beta, non-erythrocytic 5
SSBP3 single stranded DNA binding protein 3
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TCEAL2 transcription elongation factor A (SII)-like 2
TCTN2 tectonic family member 2
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRAIP TRAF interacting protein
TSHZ2 teashirt zinc finger homeobox 2
TTN titin
TTYH1 tweety family member 1
TUBA3C tubulin, alpha 3c
UPK3B uroplakin 3B
VGF VGF nerve growth factor inducible
VNN2 vanin 2
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZFP37 ZFP37 zinc finger protein
ZNF141 zinc finger protein 141
ZNF816 zinc finger protein 816