Extracellular matrix organization Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
Description A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix. (Gene Ontology, GO_0030198)
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-1474244
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Genes

266 proteins participating in the Extracellular matrix organization pathway from the Reactome Pathways dataset.

Symbol Name
A2M alpha-2-macroglobulin
ACAN aggrecan
ACTN1 actinin, alpha 1
ADAM10 ADAM metallopeptidase domain 10
ADAM15 ADAM metallopeptidase domain 15
ADAM17 ADAM metallopeptidase domain 17
ADAM8 ADAM metallopeptidase domain 8
ADAM9 ADAM metallopeptidase domain 9
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
AGRN agrin
ASPN asporin
BCAN brevican
BGN biglycan
BMP1 bone morphogenetic protein 1
BMP10 bone morphogenetic protein 10
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
BSG basigin (Ok blood group)
CAPN1 calpain 1, (mu/I) large subunit
CAPNS1 calpain, small subunit 1
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CD151 CD151 molecule (Raph blood group)
CD44 CD44 molecule (Indian blood group)
CD47 CD47 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8
CMA1 chymase 1, mast cell
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COL11A2 collagen, type XI, alpha 2
COL12A1 collagen, type XII, alpha 1
COL13A1 collagen, type XIII, alpha 1
COL14A1 collagen, type XIV, alpha 1
COL15A1 collagen, type XV, alpha 1
COL16A1 collagen, type XVI, alpha 1
COL17A1 collagen, type XVII, alpha 1
COL18A1 collagen, type XVIII, alpha 1
COL19A1 collagen, type XIX, alpha 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL20A1 collagen, type XX, alpha 1
COL21A1 collagen, type XXI, alpha 1
COL22A1 collagen, type XXII, alpha 1
COL23A1 collagen, type XXIII, alpha 1
COL24A1 collagen, type XXIV, alpha 1
COL25A1 collagen, type XXV, alpha 1
COL26A1 collagen, type XXVI, alpha 1
COL27A1 collagen, type XXVII, alpha 1
COL28A1 collagen, type XXVIII, alpha 1
COL2A1 collagen, type II, alpha 1
COL3A1 collagen, type III, alpha 1
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL4A4 collagen, type IV, alpha 4
COL4A5 collagen, type IV, alpha 5
COL4A6 collagen, type IV, alpha 6
COL5A1 collagen, type V, alpha 1
COL5A2 collagen, type V, alpha 2
COL5A3 collagen, type V, alpha 3
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
COL6A3 collagen, type VI, alpha 3
COL6A5 collagen, type VI, alpha 5
COL6A6 collagen, type VI, alpha 6
COL7A1 collagen, type VII, alpha 1
COL8A1 collagen, type VIII, alpha 1
COL8A2 collagen, type VIII, alpha 2
COL9A1 collagen, type IX, alpha 1
COL9A2 collagen, type IX, alpha 2
COL9A3 collagen, type IX, alpha 3
COLGALT1 collagen beta(1-O)galactosyltransferase 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
COMP cartilage oligomeric matrix protein
CRTAP cartilage associated protein
CTRB1 chymotrypsinogen B1
CTRB2 chymotrypsinogen B2
CTSB cathepsin B
CTSD cathepsin D
CTSG cathepsin G
CTSK cathepsin K
CTSL cathepsin L
CTSS cathepsin S
CTSV cathepsin V
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DCN decorin
DDR1 discoidin domain receptor tyrosine kinase 1
DDR2 discoidin domain receptor tyrosine kinase 2
DMD dystrophin
DMP1 dentin matrix acidic phosphoprotein 1
DSPP dentin sialophosphoprotein
DST dystonin
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
ELANE elastase, neutrophil expressed
ELN elastin
F11R F11 receptor
FBLN1 fibulin 1
FBLN2 fibulin 2
FBLN5 fibulin 5
FBN1 fibrillin 1
FBN2 fibrillin 2
FBN3 fibrillin 3
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGF2 fibroblast growth factor 2 (basic)
FGG fibrinogen gamma chain
FMOD fibromodulin
FN1 fibronectin 1
FURIN furin (paired basic amino acid cleaving enzyme)
GDF5 growth differentiation factor 5
HAPLN1 hyaluronan and proteoglycan link protein 1
HSPG2 heparan sulfate proteoglycan 2
IBSP integrin-binding sialoprotein
ICAM1 intercellular adhesion molecule 1
ICAM2 intercellular adhesion molecule 2
ICAM3 intercellular adhesion molecule 3
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
ITGA1 integrin, alpha 1
ITGA10 integrin, alpha 10
ITGA11 integrin, alpha 11
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA6 integrin, alpha 6
ITGA7 integrin, alpha 7
ITGA8 integrin, alpha 8
ITGA9 integrin, alpha 9
ITGAD integrin, alpha D
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAV integrin, alpha V
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB4 integrin, beta 4
ITGB5 integrin, beta 5
ITGB6 integrin, beta 6
ITGB7 integrin, beta 7
ITGB8 integrin, beta 8
JAM2 junctional adhesion molecule 2
JAM3 junctional adhesion molecule 3
KDR kinase insert domain receptor
KLK2 kallikrein-related peptidase 2
KLK7 kallikrein-related peptidase 7
KLKB1 kallikrein B, plasma (Fletcher factor) 1
LAMA1 laminin, alpha 1
LAMA2 laminin, alpha 2
LAMA3 laminin, alpha 3
LAMA4 laminin, alpha 4
LAMA5 laminin, alpha 5
LAMB1 laminin, beta 1
LAMB2 laminin, beta 2 (laminin S)
LAMB3 laminin, beta 3
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAMC2 laminin, gamma 2
LAMC3 laminin, gamma 3
LOX lysyl oxidase
LOXL1 lysyl oxidase-like 1
LOXL2 lysyl oxidase-like 2
LOXL3 lysyl oxidase-like 3
LOXL4 lysyl oxidase-like 4
LRP4 low density lipoprotein receptor-related protein 4
LTBP1 latent transforming growth factor beta binding protein 1
LTBP2 latent transforming growth factor beta binding protein 2
LTBP3 latent transforming growth factor beta binding protein 3
LTBP4 latent transforming growth factor beta binding protein 4
LUM lumican
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MATN1 matrilin 1, cartilage matrix protein
MATN3 matrilin 3
MATN4 matrilin 4
MFAP1 microfibrillar-associated protein 1
MFAP2 microfibrillar-associated protein 2
MFAP3 microfibrillar-associated protein 3
MFAP4 microfibrillar-associated protein 4
MFAP5 microfibrillar associated protein 5
MMP1 matrix metallopeptidase 1
MMP10 matrix metallopeptidase 10
MMP11 matrix metallopeptidase 11
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP19 matrix metallopeptidase 19
MMP2 matrix metallopeptidase 2
MMP20 matrix metallopeptidase 20
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MMP25 matrix metallopeptidase 25
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MUSK muscle, skeletal, receptor tyrosine kinase
NCAM1 neural cell adhesion molecule 1
NCAN neurocan
NCSTN nicastrin
NID1 nidogen 1
NID2 nidogen 2 (osteonidogen)
NRXN1 neurexin 1
NTN4 netrin 4
P3H1 prolyl 3-hydroxylase 1
P3H2 prolyl 3-hydroxylase 2
P3H3 prolyl 3-hydroxylase 3
P4HB prolyl 4-hydroxylase, beta polypeptide
PCOLCE procollagen C-endopeptidase enhancer
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PECAM1 platelet/endothelial cell adhesion molecule 1
PLEC plectin
PLG plasminogen
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PPIB peptidylprolyl isomerase B (cyclophilin B)
PRKCA protein kinase C, alpha
PRSS1 protease, serine, 1 (trypsin 1)
PRSS2 protease, serine, 2 (trypsin 2)
PSEN1 presenilin 1
PTPRS protein tyrosine phosphatase, receptor type, S
SDC1 syndecan 1
SDC2 syndecan 2
SDC3 syndecan 3
SDC4 syndecan 4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPP1 secreted phosphoprotein 1
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TLL1 tolloid-like 1
TLL2 tolloid-like 2
TNC tenascin C
TNN tenascin N
TNR tenascin R
TNXB tenascin XB
TPSAB1 tryptase alpha/beta 1
TRAPPC4 trafficking protein particle complex 4
TTR transthyretin
VCAM1 vascular cell adhesion molecule 1
VCAN versican
VTN vitronectin