Escherichia coli infection of the central nervous system_CNS - Brain (MMHCC)_GSE3253 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE3253
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Genes

600 genes differentially expressed during Escherichia coli infection of the central nervous system_CNS - Brain (MMHCC)_GSE3253 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
FMNL2 formin-like 2 4.62394
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 3.62303
ERRFI1 ERBB receptor feedback inhibitor 1 3.44448
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 3.2276
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 3.2221
CLIC4 chloride intracellular channel 4 3.14041
PNP purine nucleoside phosphorylase 3.11802
TRAPPC2 trafficking protein particle complex 2 3.07024
PHACTR3 phosphatase and actin regulator 3 3.06763
TMEM9B TMEM9 domain family, member B 3.04072
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 3.02968
MGP matrix Gla protein 2.92673
ECI2 enoyl-CoA delta isomerase 2 2.90055
LSAMP limbic system-associated membrane protein 2.89513
LGALS9B lectin, galactoside-binding, soluble, 9B 2.87041
MCL1 myeloid cell leukemia 1 2.85812
TK2 thymidine kinase 2, mitochondrial 2.82458
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 2.81701
FZD2 frizzled class receptor 2 2.75926
SCG3 secretogranin III 2.73879
IRF1 interferon regulatory factor 1 2.69508
C1QB complement component 1, q subcomponent, B chain 2.68953
TIMP4 TIMP metallopeptidase inhibitor 4 2.65259
GLB1 galactosidase, beta 1 2.63178
AMPD3 adenosine monophosphate deaminase 3 2.61765
OXLD1 oxidoreductase-like domain containing 1 2.61634
IER3 immediate early response 3 2.60941
SOCS3 suppressor of cytokine signaling 3 2.59096
COTL1 coactosin-like F-actin binding protein 1 2.5118
HSBP1 heat shock factor binding protein 1 2.48099
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 2.48006
ZFAND4 zinc finger, AN1-type domain 4 2.47366
RRAGC Ras-related GTP binding C 2.46457
SNX1 sorting nexin 1 2.45862
SGK1 serum/glucocorticoid regulated kinase 1 2.45137
METTL21A methyltransferase like 21A 2.43768
CNBP CCHC-type zinc finger, nucleic acid binding protein 2.41108
TMCO1 transmembrane and coiled-coil domains 1 2.39738
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 2.39577
GPHN gephyrin 2.3903
PARP12 poly (ADP-ribose) polymerase family, member 12 2.38899
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.37653
METTL18 methyltransferase like 18 2.36508
COPS7B COP9 signalosome subunit 7B 2.3625
PDK2 pyruvate dehydrogenase kinase, isozyme 2 2.3215
NTAN1 N-terminal asparagine amidase 2.2979
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 2.27605
AKAP12 A kinase (PRKA) anchor protein 12 2.25976
DTX3L deltex 3 like, E3 ubiquitin ligase 2.22682
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 2.22215
IFITM3 interferon induced transmembrane protein 3 2.21733
TPP1 tripeptidyl peptidase I 2.16529
DEGS1 delta(4)-desaturase, sphingolipid 1 2.14454
CENPT centromere protein T 2.14037
ADAM9 ADAM metallopeptidase domain 9 2.13798
TET2 tet methylcytosine dioxygenase 2 2.12158
BCL6 B-cell CLL/lymphoma 6 2.0642
HSDL1 hydroxysteroid dehydrogenase like 1 2.05728
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 2.0442
HTRA1 HtrA serine peptidase 1 2.03981
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 2.02405
RBMS1 RNA binding motif, single stranded interacting protein 1 2.01537
COL4A1 collagen, type IV, alpha 1 2.01402
RHOU ras homolog family member U 2.00408
LPIN1 lipin 1 2.00127
HSPA2 heat shock 70kDa protein 2 1.98817
OASL 2'-5'-oligoadenylate synthetase-like 1.98451
AMZ2 archaelysin family metallopeptidase 2 1.97127
FAM107A family with sequence similarity 107, member A 1.96529
AKAP2 A kinase (PRKA) anchor protein 2 1.95671
ACTR6 ARP6 actin-related protein 6 homolog (yeast) 1.95656
RHOJ ras homolog family member J 1.94514
SLC36A4 solute carrier family 36 (proton/amino acid symporter), member 4 1.94313
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 1.9427
LRRC8A leucine rich repeat containing 8 family, member A 1.9422
FGFR1 fibroblast growth factor receptor 1 1.94162
GPSM1 G-protein signaling modulator 1 1.92752
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 1.92429
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 1.91534
PXDN peroxidasin 1.91151
DDIT4 DNA-damage-inducible transcript 4 1.89987
ITFG1 integrin alpha FG-GAP repeat containing 1 1.8938
FSTL1 follistatin-like 1 1.88774
SAMD9L sterile alpha motif domain containing 9-like 1.88024
CP ceruloplasmin (ferroxidase) 1.87719
KDM1A lysine (K)-specific demethylase 1A 1.8767
CADPS Ca++-dependent secretion activator 1.87634
UCKL1 uridine-cytidine kinase 1-like 1 1.86055
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 1.85569
PARP9 poly (ADP-ribose) polymerase family, member 9 1.85077
ZNF318 zinc finger protein 318 1.84412
VIP vasoactive intestinal peptide 1.83341
DCAF11 DDB1 and CUL4 associated factor 11 1.82079
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 1.81993
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 1.81688
RUFY1 RUN and FYVE domain containing 1 1.80998
FBXL17 F-box and leucine-rich repeat protein 17 1.80666
LHFP lipoma HMGIC fusion partner 1.79921
TOR1AIP1 torsin A interacting protein 1 1.79718
STX16 syntaxin 16 1.77899
SLITRK1 SLIT and NTRK-like family, member 1 1.77879
JAGN1 jagunal homolog 1 (Drosophila) 1.77798
F3 coagulation factor III (thromboplastin, tissue factor) 1.77392
NICN1 nicolin 1 1.75866
CNTLN centlein, centrosomal protein 1.75408
FLOT2 flotillin 2 1.75399
TSC2 tuberous sclerosis 2 1.75236
CADM1 cell adhesion molecule 1 1.75155
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 1.74427
TMEM194A transmembrane protein 194A 1.74374
ARFGEF3 ARFGEF family member 3 1.72654
C5ORF51 chromosome 5 open reading frame 51 1.7219
SRSF6 serine/arginine-rich splicing factor 6 1.71603
LYRM2 LYR motif containing 2 1.71558
PLEK pleckstrin 1.71461
MYO5A myosin VA (heavy chain 12, myoxin) 1.71413
IPO4 importin 4 1.71079
NINJ1 ninjurin 1 1.70954
IFI16 interferon, gamma-inducible protein 16 1.7082
GSTZ1 glutathione S-transferase zeta 1 1.7022
CMIP c-Maf inducing protein 1.69754
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 1.69637
GPATCH8 G patch domain containing 8 1.69357
OCIAD2 OCIA domain containing 2 1.6933
C16ORF72 chromosome 16 open reading frame 72 1.69132
USP18 ubiquitin specific peptidase 18 1.69012
RHOB ras homolog family member B 1.68443
SELM selenoprotein M 1.6821
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.67771
KLF15 Kruppel-like factor 15 1.67516
IFI44 interferon-induced protein 44 1.66735
CHRD chordin 1.66366
SSBP2 single-stranded DNA binding protein 2 1.6604
RHOC ras homolog family member C 1.65807
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 1.65622
LGI3 leucine-rich repeat LGI family, member 3 1.65073
SAP30 Sin3A-associated protein, 30kDa 1.65019
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 1.64737
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 1.64586
CXCL14 chemokine (C-X-C motif) ligand 14 1.64494
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 1.6441
ADCY9 adenylate cyclase 9 1.64332
PEA15 phosphoprotein enriched in astrocytes 15 1.6426
GREM2 gremlin 2, DAN family BMP antagonist 1.64205
CRTAM cytotoxic and regulatory T cell molecule 1.6333
SYNGR2 synaptogyrin 2 1.62865
MKL1 megakaryoblastic leukemia (translocation) 1 1.62476
CDK11A cyclin-dependent kinase 11A 1.62314
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y 1.61921
SCARB2 scavenger receptor class B, member 2 1.61888
KBTBD7 kelch repeat and BTB (POZ) domain containing 7 1.61884
GHITM growth hormone inducible transmembrane protein 1.61068
DAAM2 dishevelled associated activator of morphogenesis 2 1.60403
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 1.60281
SHISA5 shisa family member 5 1.59953
IPO9 importin 9 1.59837
CCNDBP1 cyclin D-type binding-protein 1 1.59637
JUN jun proto-oncogene 1.59619
DENND4B DENN/MADD domain containing 4B 1.59379
SPNS2 spinster homolog 2 (Drosophila) 1.59182
MFSD2A major facilitator superfamily domain containing 2A 1.58961
ZFP36 ZFP36 ring finger protein 1.58654
KCNK1 potassium channel, two pore domain subfamily K, member 1 1.58634
CSF3 colony stimulating factor 3 (granulocyte) 1.56985
PBX2 pre-B-cell leukemia homeobox 2 1.5697
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 1.56588
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) 1.56368
TMEM50A transmembrane protein 50A 1.56268
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 1.56065
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 1.55962
PHC1 polyhomeotic homolog 1 (Drosophila) 1.55956
PLA2G4E phospholipase A2, group IVE 1.55795
FBXW5 F-box and WD repeat domain containing 5 1.5579
CCDC127 coiled-coil domain containing 127 1.5576
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 1.55701
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 1.55555
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 1.55124
GLG1 golgi glycoprotein 1 1.55031
RNH1 ribonuclease/angiogenin inhibitor 1 1.54977
TSC22D3 TSC22 domain family, member 3 1.54726
CCNH cyclin H 1.54659
TCP11L2 t-complex 11, testis-specific-like 2 1.53939
SEPP1 selenoprotein P, plasma, 1 1.53803
COMMD7 COMM domain containing 7 1.53355
GPR6 G protein-coupled receptor 6 1.5317
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 1.52991
PARP10 poly (ADP-ribose) polymerase family, member 10 1.52574
GADD45G growth arrest and DNA-damage-inducible, gamma 1.52051
TSPYL2 TSPY-like 2 1.51944
ARRDC3 arrestin domain containing 3 1.51854
LRRC58 leucine rich repeat containing 58 1.51507
FAM114A2 family with sequence similarity 114, member A2 1.51483
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 1.51413
HAP1 huntingtin-associated protein 1 1.5104
FBXL5 F-box and leucine-rich repeat protein 5 1.50876
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.50867
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 1.50793
DAZAP2 DAZ associated protein 2 1.50701
SEC23B Sec23 homolog B (S. cerevisiae) 1.50608
EIF1AX eukaryotic translation initiation factor 1A, X-linked 1.50343
GJB6 gap junction protein, beta 6, 30kDa 1.50173
TP53BP2 tumor protein p53 binding protein 2 1.50142
CHID1 chitinase domain containing 1 1.50094
GRWD1 glutamate-rich WD repeat containing 1 1.50091
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 1.50073
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 1.50065
TMEM216 transmembrane protein 216 1.49887
POLR2M polymerase (RNA) II (DNA directed) polypeptide M 1.49691
NPTX1 neuronal pentraxin I 1.49605
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.49522
SPRYD7 SPRY domain containing 7 1.49286
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 1.4928
IFITM2 interferon induced transmembrane protein 2 1.49159
PCID2 PCI domain containing 2 1.49103
PRPF40B PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) 1.48626
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 1.48406
MAP2K1 mitogen-activated protein kinase kinase 1 1.48233
MPPED2 metallophosphoesterase domain containing 2 1.482
EHD3 EH-domain containing 3 1.48152
CD14 CD14 molecule 1.48042
CDK7 cyclin-dependent kinase 7 1.4801
NUAK2 NUAK family, SNF1-like kinase, 2 1.47378
HEPACAM hepatic and glial cell adhesion molecule 1.46959
UBE2N ubiquitin-conjugating enzyme E2N 1.46791
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.46509
CRLS1 cardiolipin synthase 1 1.46504
ZBTB16 zinc finger and BTB domain containing 16 1.46456
SP2 Sp2 transcription factor 1.46219
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.45484
COMMD3 COMM domain containing 3 1.44813
TMED9 transmembrane emp24 protein transport domain containing 9 1.44654
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.44566
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 1.44536
DENND3 DENN/MADD domain containing 3 1.44407
CYB561 cytochrome b561 1.44374
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 1.44329
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 1.44248
IRF9 interferon regulatory factor 9 1.43779
CGGBP1 CGG triplet repeat binding protein 1 1.43716
IFRD1 interferon-related developmental regulator 1 1.43687
PHF21A PHD finger protein 21A 1.43465
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 1.43363
DPH3 diphthamide biosynthesis 3 1.43194
KLHL9 kelch-like family member 9 1.43148
ANKRD13A ankyrin repeat domain 13A 1.4312
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 1.42888
WDR7 WD repeat domain 7 1.42577
C12ORF4 chromosome 12 open reading frame 4 1.42257
GRB2 growth factor receptor-bound protein 2 1.42237
PHYH phytanoyl-CoA 2-hydroxylase 1.42137
RASD1 RAS, dexamethasone-induced 1 1.41457
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 1.413
ATG14 autophagy related 14 1.41144
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 1.41098
MAT2A methionine adenosyltransferase II, alpha 1.41045
PREB prolactin regulatory element binding 1.40533
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 1.40495
FRMPD1 FERM and PDZ domain containing 1 1.40384
OCIAD1 OCIA domain containing 1 1.40304
L3MBTL2 l(3)mbt-like 2 (Drosophila) 1.40228
ERGIC3 ERGIC and golgi 3 1.40133
RSAD2 radical S-adenosyl methionine domain containing 2 1.3976
PTPDC1 protein tyrosine phosphatase domain containing 1 1.39511
SLFN5 schlafen family member 5 1.39285
BCL2L13 BCL2-like 13 (apoptosis facilitator) 1.39218
LRRC61 leucine rich repeat containing 61 1.38202
LMTK2 lemur tyrosine kinase 2 1.37802
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 1.37661
PHKG2 phosphorylase kinase, gamma 2 (testis) 1.37456
STXBP5 syntaxin binding protein 5 (tomosyn) 1.37243
MRPS18B mitochondrial ribosomal protein S18B 1.37083
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 1.37023
ZNF519 zinc finger protein 519 1.36912
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) 1.36811
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 1.36751
TSPO translocator protein (18kDa) 1.36679
NCDN neurochondrin 1.36656
GPR83 G protein-coupled receptor 83 1.36157
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 1.36096
CLSTN1 calsyntenin 1 1.35991
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.35974
GID8 GID complex subunit 8 1.35887
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 1.35643
LRIF1 ligand dependent nuclear receptor interacting factor 1 1.35574
SKP1 S-phase kinase-associated protein 1 1.35543
ASTN1 astrotactin 1 1.35417
HRH3 histamine receptor H3 1.35378
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 1.35175
IRF2BP2 interferon regulatory factor 2 binding protein 2 1.35039
KDM2B lysine (K)-specific demethylase 2B 1.34638
ACVR2A activin A receptor, type IIA 1.34602
GLO1 glyoxalase I 1.34597
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 1.34597
CRTC1 CREB regulated transcription coactivator 1 1.34465
NECAB2 N-terminal EF-hand calcium binding protein 2 1.34324
TUSC3 tumor suppressor candidate 3 1.3428
CTIF CBP80/20-dependent translation initiation factor 1.34266
GPR22 G protein-coupled receptor 22 1.3418
LONRF3 LON peptidase N-terminal domain and ring finger 3 1.34172
PDE9A phosphodiesterase 9A 1.34135

decreased expression

Symbol Name Standardized Value
RFXAP regulatory factor X-associated protein -3.82874
PGAM1 phosphoglycerate mutase 1 (brain) -3.14939
CDC5L cell division cycle 5-like -2.99484
AHCTF1 AT hook containing transcription factor 1 -2.88677
EI24 etoposide induced 2.4 -2.82423
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -2.75726
EGFL7 EGF-like-domain, multiple 7 -2.7434
EIF3C eukaryotic translation initiation factor 3, subunit C -2.62632
EID2 EP300 interacting inhibitor of differentiation 2 -2.58335
OSBPL8 oxysterol binding protein-like 8 -2.58334
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -2.57168
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 -2.55797
COL27A1 collagen, type XXVII, alpha 1 -2.54203
EMB embigin -2.52013
SAP18 Sin3A-associated protein, 18kDa -2.51398
MARK3 MAP/microtubule affinity-regulating kinase 3 -2.47125
C17ORF75 chromosome 17 open reading frame 75 -2.46674
ALKBH5 AlkB family member 5, RNA demethylase -2.46389
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 -2.42467
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A -2.40068
NTM neurotrimin -2.39786
MAOA monoamine oxidase A -2.35671
POLR1C polymerase (RNA) I polypeptide C, 30kDa -2.33895
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -2.33855
SLCO1C1 solute carrier organic anion transporter family, member 1C1 -2.33528
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 -2.31681
CXXC5 CXXC finger protein 5 -2.29475
UBASH3B ubiquitin associated and SH3 domain containing B -2.28362
CLTB clathrin, light chain B -2.28188
FGD5 FYVE, RhoGEF and PH domain containing 5 -2.27759
ELP2 elongator acetyltransferase complex subunit 2 -2.27424
ZNF280D zinc finger protein 280D -2.2398
C1ORF21 chromosome 1 open reading frame 21 -2.22942
MID1IP1 MID1 interacting protein 1 -2.20469
CPSF3L cleavage and polyadenylation specific factor 3-like -2.18341
FBL fibrillarin -2.1791
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -2.17049
SYN2 synapsin II -2.15037
GPM6B glycoprotein M6B -2.13941
EGR1 early growth response 1 -2.12769
CHGB chromogranin B -2.10905
STAU2 staufen double-stranded RNA binding protein 2 -2.09868
SWT1 SWT1 RNA endoribonuclease homolog (S. cerevisiae) -2.09823
YEATS4 YEATS domain containing 4 -2.0619
PHB2 prohibitin 2 -2.0612
RNF121 ring finger protein 121 -2.05429
CTCF CCCTC-binding factor (zinc finger protein) -2.05111
PPAP2B phosphatidic acid phosphatase type 2B -2.04968
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa -2.03795
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -2.03668
DUSP14 dual specificity phosphatase 14 -2.03328
FMOD fibromodulin -2.03197
PKP4 plakophilin 4 -2.03042
UBN1 ubinuclein 1 -2.02736
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.02236
RGS7BP regulator of G-protein signaling 7 binding protein -2.0204
LYPLA2 lysophospholipase II -2.01435
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) -2.00964
SNRK SNF related kinase -2.00863
ITM2A integral membrane protein 2A -2.0043
RARS arginyl-tRNA synthetase -2.00031
NUAK1 NUAK family, SNF1-like kinase, 1 -1.9965
SYNE1 spectrin repeat containing, nuclear envelope 1 -1.98805
FAM126B family with sequence similarity 126, member B -1.98463
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha -1.98356
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 -1.97597
C14ORF1 chromosome 14 open reading frame 1 -1.97075
CLDN5 claudin 5 -1.96731
COQ10B coenzyme Q10 homolog B (S. cerevisiae) -1.96514
TRPM2 transient receptor potential cation channel, subfamily M, member 2 -1.96459
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -1.9579
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -1.95724
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) -1.9442
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 -1.9351
RASA2 RAS p21 protein activator 2 -1.9343
MAGT1 magnesium transporter 1 -1.93322
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) -1.92336
FBXO33 F-box protein 33 -1.9228
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase -1.91039
EYA3 EYA transcriptional coactivator and phosphatase 3 -1.90579
PHF20L1 PHD finger protein 20-like 1 -1.88967
LPAR1 lysophosphatidic acid receptor 1 -1.87834
TEK TEK tyrosine kinase, endothelial -1.8774
RELL2 RELT-like 2 -1.87566
HEMK1 HemK methyltransferase family member 1 -1.86747
ZMYM5 zinc finger, MYM-type 5 -1.86506
COPS4 COP9 signalosome subunit 4 -1.86376
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa -1.85782
SET SET nuclear proto-oncogene -1.85753
MRFAP1 Morf4 family associated protein 1 -1.85404
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 -1.84583
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 -1.84415
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -1.83766
PDCD6 programmed cell death 6 -1.83694
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -1.82865
CIRH1A cirrhosis, autosomal recessive 1A (cirhin) -1.82277
GDAP2 ganglioside induced differentiation associated protein 2 -1.81816
MRPL49 mitochondrial ribosomal protein L49 -1.81796
BCL10 B-cell CLL/lymphoma 10 -1.81795
SDPR serum deprivation response -1.81703
SYNJ2BP synaptojanin 2 binding protein -1.80967
LUC7L3 LUC7-like 3 (S. cerevisiae) -1.8069
PAOX polyamine oxidase (exo-N4-amino) -1.80331
PITPNA phosphatidylinositol transfer protein, alpha -1.79683
CSNK2A2 casein kinase 2, alpha prime polypeptide -1.79452
ARGLU1 arginine and glutamate rich 1 -1.79021
ZDHHC21 zinc finger, DHHC-type containing 21 -1.78339
SSRP1 structure specific recognition protein 1 -1.78123
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -1.77733
ANKRD11 ankyrin repeat domain 11 -1.77682
C7ORF60 chromosome 7 open reading frame 60 -1.76715
RNF6 ring finger protein (C3H2C3 type) 6 -1.75932
RND3 Rho family GTPase 3 -1.75511
KLF10 Kruppel-like factor 10 -1.75262
VWA1 von Willebrand factor A domain containing 1 -1.74819
RAB39B RAB39B, member RAS oncogene family -1.74591
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -1.74306
FAM98A family with sequence similarity 98, member A -1.74021
RNF130 ring finger protein 130 -1.73715
ITM2C integral membrane protein 2C -1.73212
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -1.73207
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -1.72776
FGF12 fibroblast growth factor 12 -1.72329
RPA1 replication protein A1, 70kDa -1.72052
LPIN2 lipin 2 -1.71907
TROVE2 TROVE domain family, member 2 -1.71151
GDAP1 ganglioside induced differentiation associated protein 1 -1.70752
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -1.70528
GINS4 GINS complex subunit 4 (Sld5 homolog) -1.70478
FBXO25 F-box protein 25 -1.69151
MRPS9 mitochondrial ribosomal protein S9 -1.69138
PHF23 PHD finger protein 23 -1.69045
SCAF11 SR-related CTD-associated factor 11 -1.69037
NRN1 neuritin 1 -1.6903
SH3BP5L SH3-binding domain protein 5-like -1.68791
TTC3 tetratricopeptide repeat domain 3 -1.68785
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 -1.68758
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -1.68133
BOD1 biorientation of chromosomes in cell division 1 -1.67908
CAPNS1 calpain, small subunit 1 -1.67713
PTPN9 protein tyrosine phosphatase, non-receptor type 9 -1.67302
GTF2IRD1 GTF2I repeat domain containing 1 -1.67129
LRRC47 leucine rich repeat containing 47 -1.66994
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -1.66193
PANK3 pantothenate kinase 3 -1.65111
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 -1.64105
TNRC6B trinucleotide repeat containing 6B -1.64075
UBXN4 UBX domain protein 4 -1.63844
GPR12 G protein-coupled receptor 12 -1.6362
AARS alanyl-tRNA synthetase -1.63614
LONRF1 LON peptidase N-terminal domain and ring finger 1 -1.63196
BDNF brain-derived neurotrophic factor -1.62429
GAPVD1 GTPase activating protein and VPS9 domains 1 -1.62321
ACBD3 acyl-CoA binding domain containing 3 -1.61865
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta -1.61793
RTN4 reticulon 4 -1.61433
CNTN6 contactin 6 -1.61414
ING1 inhibitor of growth family, member 1 -1.6107
NPY5R neuropeptide Y receptor Y5 -1.61043
KLF7 Kruppel-like factor 7 (ubiquitous) -1.60396
TMEM165 transmembrane protein 165 -1.60391
HEXB hexosaminidase B (beta polypeptide) -1.59538
SOX17 SRY (sex determining region Y)-box 17 -1.59531
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -1.59306
DNM3 dynamin 3 -1.58824
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -1.58762
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 -1.57986
NUP88 nucleoporin 88kDa -1.57966
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -1.57761
CACNB4 calcium channel, voltage-dependent, beta 4 subunit -1.57601
KIAA1107 KIAA1107 -1.57556
PPP1R12A protein phosphatase 1, regulatory subunit 12A -1.57325
MTSS1 metastasis suppressor 1 -1.57176
LRRC45 leucine rich repeat containing 45 -1.57088
STMN2 stathmin 2 -1.56743
RCOR1 REST corepressor 1 -1.56533
PHLDB1 pleckstrin homology-like domain, family B, member 1 -1.56491
COL7A1 collagen, type VII, alpha 1 -1.56195
CALB1 calbindin 1, 28kDa -1.56155
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -1.561
DTX4 deltex 4, E3 ubiquitin ligase -1.55947
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 -1.55676
RPS24 ribosomal protein S24 -1.55385
GCLC glutamate-cysteine ligase, catalytic subunit -1.55281
GOPC golgi-associated PDZ and coiled-coil motif containing -1.55181
OSBPL2 oxysterol binding protein-like 2 -1.55144
CA2 carbonic anhydrase II -1.54874
PRMT2 protein arginine methyltransferase 2 -1.54854
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -1.54624
SOX2 SRY (sex determining region Y)-box 2 -1.54415
VDAC2 voltage-dependent anion channel 2 -1.54226
CLUAP1 clusterin associated protein 1 -1.542
IQGAP2 IQ motif containing GTPase activating protein 2 -1.54155
AP4S1 adaptor-related protein complex 4, sigma 1 subunit -1.54128
STX12 syntaxin 12 -1.53937
MBP myelin basic protein -1.5367
CS citrate synthase -1.53227
FAM102B family with sequence similarity 102, member B -1.53123
PTRH2 peptidyl-tRNA hydrolase 2 -1.52269
RSF1 remodeling and spacing factor 1 -1.52092
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) -1.51728
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -1.51714
MRPL50 mitochondrial ribosomal protein L50 -1.51435
HADH hydroxyacyl-CoA dehydrogenase -1.51203
N4BP2L1 NEDD4 binding protein 2-like 1 -1.51164
NDEL1 nudE neurodevelopment protein 1-like 1 -1.50587
PCBP1 poly(rC) binding protein 1 -1.50318
RNF185 ring finger protein 185 -1.50127
PCDH9 protocadherin 9 -1.50103
DPY19L1 dpy-19-like 1 (C. elegans) -1.49939
RSPRY1 ring finger and SPRY domain containing 1 -1.48573
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -1.48541
ACSL5 acyl-CoA synthetase long-chain family member 5 -1.48402
ANAPC2 anaphase promoting complex subunit 2 -1.48126
ATM ATM serine/threonine kinase -1.48035
MBLAC2 metallo-beta-lactamase domain containing 2 -1.48016
MAPRE1 microtubule-associated protein, RP/EB family, member 1 -1.4797
CCKBR cholecystokinin B receptor -1.47901
DUSP6 dual specificity phosphatase 6 -1.47863
PUM1 pumilio RNA-binding family member 1 -1.4786
RPN1 ribophorin I -1.4752
RBM26 RNA binding motif protein 26 -1.47236
FAM169A family with sequence similarity 169, member A -1.46812
BRD2 bromodomain containing 2 -1.46354
RABGGTB Rab geranylgeranyltransferase, beta subunit -1.46087
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 -1.45604
KIAA0430 KIAA0430 -1.45546
CCNYL1 cyclin Y-like 1 -1.45426
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -1.45384
SCN1A sodium channel, voltage gated, type I alpha subunit -1.44966
RPAP2 RNA polymerase II associated protein 2 -1.4483
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -1.44781
FLT1 fms-related tyrosine kinase 1 -1.44493
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -1.44408
TJP1 tight junction protein 1 -1.44274
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) -1.44011
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -1.43943
XKR6 XK, Kell blood group complex subunit-related family, member 6 -1.43847
RAB6A RAB6A, member RAS oncogene family -1.43821
GARS glycyl-tRNA synthetase -1.43735
UBXN1 UBX domain protein 1 -1.43727
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) -1.43531
GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 -1.43293
RPH3A rabphilin 3A -1.43239
DKC1 dyskeratosis congenita 1, dyskerin -1.43175
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -1.43154
NCALD neurocalcin delta -1.42919
SPPL3 signal peptide peptidase like 3 -1.4266
RAB14 RAB14, member RAS oncogene family -1.42043
FAM168A family with sequence similarity 168, member A -1.42038
RNF19B ring finger protein 19B -1.41636
DESI2 desumoylating isopeptidase 2 -1.41609
CLK3 CDC-like kinase 3 -1.41202
TUBGCP4 tubulin, gamma complex associated protein 4 -1.41182
LIN7A lin-7 homolog A (C. elegans) -1.41092
EIF3A eukaryotic translation initiation factor 3, subunit A -1.41006
SDK2 sidekick cell adhesion molecule 2 -1.4094
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -1.40894
DGAT1 diacylglycerol O-acyltransferase 1 -1.40677
JPH3 junctophilin 3 -1.4066
POU6F1 POU class 6 homeobox 1 -1.40512
OSTC oligosaccharyltransferase complex subunit (non-catalytic) -1.3982
TMEM246 transmembrane protein 246 -1.39804
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -1.39783
RPS21 ribosomal protein S21 -1.39711
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -1.39649
PARD6A par-6 family cell polarity regulator alpha -1.39534
DYNLT3 dynein, light chain, Tctex-type 3 -1.39379
BTBD10 BTB (POZ) domain containing 10 -1.3918
RALBP1 ralA binding protein 1 -1.39168
INPP5F inositol polyphosphate-5-phosphatase F -1.39065
ALCAM activated leukocyte cell adhesion molecule -1.39057
CCDC64 coiled-coil domain containing 64 -1.38962
SLC30A5 solute carrier family 30 (zinc transporter), member 5 -1.38862
HLF hepatic leukemia factor -1.38794
QKI QKI, KH domain containing, RNA binding -1.38635
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae) -1.3851
FOXG1 forkhead box G1 -1.37552
SPRTN SprT-like N-terminal domain -1.36777
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -1.36471
COG3 component of oligomeric golgi complex 3 -1.36239
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -1.36062
IFT43 intraflagellar transport 43 -1.36057
PNN pinin, desmosome associated protein -1.36043
HAX1 HCLS1 associated protein X-1 -1.3591
SLC38A1 solute carrier family 38, member 1 -1.3568
PCNP PEST proteolytic signal containing nuclear protein -1.35524
UBFD1 ubiquitin family domain containing 1 -1.3505
HDAC5 histone deacetylase 5 -1.34942
SPAST spastin -1.34687
TFB2M transcription factor B2, mitochondrial -1.34628
PPIB peptidylprolyl isomerase B (cyclophilin B) -1.34552
FGFR1OP2 FGFR1 oncogene partner 2 -1.34435
CCND2 cyclin D2 -1.34159
ATXN7 ataxin 7 -1.34064
MRPL18 mitochondrial ribosomal protein L18 -1.34044
RCN2 reticulocalbin 2, EF-hand calcium binding domain -1.33855
RIMS1 regulating synaptic membrane exocytosis 1 -1.33559
CCP110 centriolar coiled coil protein 110kDa -1.33254
BACE1 beta-site APP-cleaving enzyme 1 -1.33219