ErbB1 downstream signaling Gene Set

Dataset PID Pathways
Category structural or functional annotations
Type pathway
External Link http://public.ndexbio.org/#/network/30d60550-6192-11e5-8ac5-06603eb7f303
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Genes

102 proteins participating in the ErbB1 downstream signaling pathway from the PID Pathways dataset.

Symbol Name
ABI1 abl-interactor 1
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ARF4 ADP-ribosylation factor 4
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ATF1 activating transcription factor 1
ATF2 activating transcription factor 2
BAD BCL2-associated agonist of cell death
BAIAP2 BAI1-associated protein 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
CAPN2 calpain 2, (m/II) large subunit
CDC42 cell division cycle 42
CHN2 chimerin 2
CREB1 cAMP responsive element binding protein 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
DIAPH3 diaphanous-related formin 3
DUSP1 dual specificity phosphatase 1
DUSP6 dual specificity phosphatase 6
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
ELK1 ELK1, member of ETS oncogene family
EPS8 epidermal growth factor receptor pathway substrate 8
F2RL2 coagulation factor II (thrombin) receptor-like 2
FOS FBJ murine osteosarcoma viral oncogene homolog
GAB1 GRB2-associated binding protein 1
GRB2 growth factor receptor-bound protein 2
HRAS Harvey rat sarcoma viral oncogene homolog
IQGAP1 IQ motif containing GTPase activating protein 1
JUN jun proto-oncogene
KSR1 kinase suppressor of ras 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAP1 mitogen-activated protein kinase associated protein 1
MEF2C myocyte enhancer factor 2C
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NCKAP1 NCK-associated protein 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PDPK1 3-phosphoinositide dependent protein kinase 1
PEBP1 phosphatidylethanolamine binding protein 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD2 phospholipase D2
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PPP5C protein phosphatase 5, catalytic subunit
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCZ protein kinase C, zeta
RAB5A RAB5A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RALGDS ral guanine nucleotide dissociation stimulator
RICTOR RPTOR independent companion of MTOR, complex 2
RIN1 Ras and Rab interactor 1
RPS6 ribosomal protein S6
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SFN stratifin
SH2D2A SH2 domain containing 2A
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMAD1 SMAD family member 1
SOS1 son of sevenless homolog 1 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
USP6NL USP6 N-terminal like
VAV2 vav 2 guanine nucleotide exchange factor
WASF2 WAS protein family, member 2
WASL Wiskott-Aldrich syndrome-like
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZFP36 ZFP36 ring finger protein