Epstein-Barr Virus Infections Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Infection with human herpesvirus 4 (HERPESVIRUS 4, HUMAN); which may facilitate the development of various lymphoproliferative disorders. These include BURKITT LYMPHOMA (African type), INFECTIOUS MONONUCLEOSIS, and oral hairy leukoplakia (LEUKOPLAKIA, HAIRY).|A Herpesviridae infectious disease that results_in infection, has_agent Human herpesvirus 4, which is transmitted_by contact with the saliva. (Experimental Factor Ontology, EFO_0000769)
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Genes

273 genes associated with the Epstein-Barr Virus Infections phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ACAA1 acetyl-CoA acyltransferase 1
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AFMID arylformamidase
AICDA activation-induced cytidine deaminase
AIRE autoimmune regulator
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALAS1 5'-aminolevulinate synthase 1
ALS2CR12 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12
ANPEP alanyl (membrane) aminopeptidase
AP1M2 adaptor-related protein complex 1, mu 2 subunit
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAK1P1 BCL2-antagonist/killer 1 pseudogene 1
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL10 B-cell CLL/lymphoma 10
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BLNK B-cell linker
BRAF B-Raf proto-oncogene, serine/threonine kinase
BYSL bystin-like
C11ORF31 chromosome 11 open reading frame 31
C16ORF70 chromosome 16 open reading frame 70
C9ORF9 chromosome 9 open reading frame 9
CARD18 caspase recruitment domain family, member 18
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC183 coiled-coil domain containing 183
CCL2 chemokine (C-C motif) ligand 2
CCNA1 cyclin A1
CCND2 cyclin D2
CCND3 cyclin D3
CCNE1 cyclin E1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR7 chemokine (C-C motif) receptor 7
CD14 CD14 molecule
CD180 CD180 molecule
CD2 CD2 molecule
CD27 CD27 molecule
CD28 CD28 molecule
CD33 CD33 molecule
CD4 CD4 molecule
CD5 CD5 molecule
CD80 CD80 molecule
CD81 CD81 molecule
CD86 CD86 molecule
CDC6 cell division cycle 6
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2A-AS1 CDKN2A antisense RNA 1 (head to head)
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CFLAR CASP8 and FADD-like apoptosis regulator
CHKA choline kinase alpha
CHUK conserved helix-loop-helix ubiquitous kinase
CPT1B carnitine palmitoyltransferase 1B (muscle)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CSDE1 cold shock domain containing E1, RNA-binding
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CYBA cytochrome b-245, alpha polypeptide
DLL3 delta-like 3 (Drosophila)
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
E2F2 E2F transcription factor 2
E2F3 E2F transcription factor 3
E2F4 E2F transcription factor 4, p107/p130-binding
E2F5 E2F transcription factor 5, p130-binding
E2F6 E2F transcription factor 6
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ERAP1 endoplasmic reticulum aminopeptidase 1
ERLIN1 ER lipid raft associated 1
FADD Fas (TNFRSF6)-associated via death domain
FAS Fas cell surface death receptor
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FGF1 fibroblast growth factor 1 (acidic)
FGF10 fibroblast growth factor 10
FGF17 fibroblast growth factor 17
FGF18 fibroblast growth factor 18
FGF2 fibroblast growth factor 2 (basic)
FGF23 fibroblast growth factor 23
FGF4 fibroblast growth factor 4
FGF8 fibroblast growth factor 8 (androgen-induced)
FGF9 fibroblast growth factor 9
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FRS2 fibroblast growth factor receptor substrate 2
G6PC3 glucose 6 phosphatase, catalytic, 3
GADD45A growth arrest and DNA-damage-inducible, alpha
GATA3 GATA binding protein 3
GFI1B growth factor independent 1B transcription repressor
GMPR2 guanosine monophosphate reductase 2
GPATCH11 G patch domain containing 11
GPX1 glutathione peroxidase 1
GRB2 growth factor receptor-bound protein 2
HAVCR2 hepatitis A virus cellular receptor 2
HCG9 HLA complex group 9 (non-protein coding)
HDAC5 histone deacetylase 5
HDAC7 histone deacetylase 7
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
IFNG interferon, gamma
IGF1R insulin-like growth factor 1 receptor
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL12B interleukin 12B
IL15 interleukin 15
IL17A interleukin 17A
IL17C interleukin 17C
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL21 interleukin 21
IL21R interleukin 21 receptor
IL2RA interleukin 2 receptor, alpha
IL6 interleukin 6
IL7 interleukin 7
IRAK2 interleukin-1 receptor-associated kinase 2
JAG2 jagged 2
JAK1 Janus kinase 1
JAK3 Janus kinase 3
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LPAR6 lysophosphatidic acid receptor 6
LPCAT2 lysophosphatidylcholine acyltransferase 2
LY96 lymphocyte antigen 96
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK14 mitogen-activated protein kinase 14
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MICB MHC class I polypeptide-related sequence B
MKRN2 makorin ring finger protein 2
MMP1 matrix metallopeptidase 1
MMP11 matrix metallopeptidase 11
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSRB1 methionine sulfoxide reductase B1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
NECAB3 N-terminal EF-hand calcium binding protein 3
NF1 neurofibromin 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NLRP12 NLR family, pyrin domain containing 12
NOD1 nucleotide-binding oligomerization domain containing 1
NTHL1 nth endonuclease III-like 1 (E. coli)
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIGU phosphatidylinositol glycan anchor biosynthesis, class U
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PKD1 polycystic kidney disease 1 (autosomal dominant)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POT1 protection of telomeres 1
PRF1 perforin 1 (pore forming protein)
PRG3 proteoglycan 3
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKRAP1 protein kinase, interferon-inducible double stranded RNA dependent activator pseudogene 1
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHEB Ras homolog enriched in brain
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK2 receptor-interacting serine-threonine kinase 2
RMDN1 regulator of microtubule dynamics 1
RNF175 ring finger protein 175
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPL3L ribosomal protein L3-like
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SARM1 sterile alpha and TIR motif containing 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SELK selenoprotein K
SELM selenoprotein M
SELV selenoprotein V
SEP15 15 kDa selenoprotein
SEPN1 selenoprotein N, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFN stratifin
SH2D1A SH2 domain containing 1A
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC44A2 solute carrier family 44 (choline transporter), member 2
SOCS2 suppressor of cytokine signaling 2
SOCS5 suppressor of cytokine signaling 5
SOCS6 suppressor of cytokine signaling 6
SOS1 son of sevenless homolog 1 (Drosophila)
SPATA32 spermatogenesis associated 32
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STK11 serine/threonine kinase 11
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBK1 TANK-binding kinase 1
TEP1 telomerase-associated protein 1
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2 telomeric repeat binding factor 2
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TICAM1 toll-like receptor adaptor molecule 1
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TLR9 toll-like receptor 9
TMED7 transmembrane emp24 protein transport domain containing 7
TMEM189 transmembrane protein 189
TMEM230 transmembrane protein 230
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOLLIP toll interacting protein
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TRAF1 TNF receptor-associated factor 1
TRAF5 TNF receptor-associated factor 5
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
UBE2N ubiquitin-conjugating enzyme E2N
ULBP1 UL16 binding protein 1
ULBP2 UL16 binding protein 2
ULBP3 UL16 binding protein 3
WWP1 WW domain containing E3 ubiquitin protein ligase 1
YY1 YY1 transcription factor