EGFR Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description epidermal growth factor receptor|The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010] (NCBI Entrez Gene Database, 1956)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_EGFR
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Genes

32 co-expressed genes for EGFR from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
ALPP alkaline phosphatase, placental
CAPN6 calpain 6
CRH corticotropin releasing hormone
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
EGFR epidermal growth factor receptor
FBN2 fibrillin 2
GCM1 glial cells missing homolog 1 (Drosophila)
GDF15 growth differentiation factor 15
GH2 growth hormone 2
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
KISS1 KiSS-1 metastasis-suppressor
LGALS14 lectin, galactoside-binding, soluble, 14
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
PAGE4 P antigen family, member 4 (prostate associated)
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAPPA2 pappalysin 2
PLAC1 placenta-specific 1
PSG1 pregnancy specific beta-1-glycoprotein 1
PSG2 pregnancy specific beta-1-glycoprotein 2
PSG3 pregnancy specific beta-1-glycoprotein 3
PSG4 pregnancy specific beta-1-glycoprotein 4
PSG5 pregnancy specific beta-1-glycoprotein 5
PSG6 pregnancy specific beta-1-glycoprotein 6
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)
PSG9 pregnancy specific beta-1-glycoprotein 9
SDC1 syndecan 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIMP2 TIMP metallopeptidase inhibitor 2