EGFR downregulation Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-182971
Similar Terms
Downloads & Tools

Genes

26 proteins participating in the EGFR downregulation pathway from the Reactome Pathways dataset.

Symbol Name
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDC42 cell division cycle 42
CLTA clathrin, light chain A
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EPN1 epsin 1
EPS15 epidermal growth factor receptor pathway substrate 15
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
GRB2 growth factor receptor-bound protein 2
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
RPS27A ribosomal protein S27a
SH3GL2 SH3-domain GRB2-like 2
SH3KBP1 SH3-domain kinase binding protein 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C