Duchenne muscular dystrophy (DMD)_Extraocular muscle_GSE1472 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1472
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Genes

600 genes differentially expressed during Duchenne muscular dystrophy (DMD)_Extraocular muscle_GSE1472 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
WSB1 WD repeat and SOCS box containing 1 2.89499
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 2.87329
AIM1 absent in melanoma 1 2.8477
SPPL3 signal peptide peptidase like 3 2.71482
COL4A1 collagen, type IV, alpha 1 2.71186
SLC4A2 solute carrier family 4 (anion exchanger), member 2 2.63162
CLK2 CDC-like kinase 2 2.6085
DAZAP2 DAZ associated protein 2 2.58449
RPL6 ribosomal protein L6 2.55765
OSMR oncostatin M receptor 2.55594
PUM2 pumilio RNA-binding family member 2 2.54954
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.54714
EFTUD2 elongation factor Tu GTP binding domain containing 2 2.54071
TSPO translocator protein (18kDa) 2.50142
EIF3B eukaryotic translation initiation factor 3, subunit B 2.49852
ACSL5 acyl-CoA synthetase long-chain family member 5 2.49027
CCT4 chaperonin containing TCP1, subunit 4 (delta) 2.47481
ZMIZ2 zinc finger, MIZ-type containing 2 2.38931
CLPTM1 cleft lip and palate associated transmembrane protein 1 2.37359
CHERP calcium homeostasis endoplasmic reticulum protein 2.3579
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 2.35511
BIRC2 baculoviral IAP repeat containing 2 2.3462
CECR6 cat eye syndrome chromosome region, candidate 6 2.34251
EMP3 epithelial membrane protein 3 2.27238
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2.26962
RPS10 ribosomal protein S10 2.26232
LAT2 linker for activation of T cells family, member 2 2.26134
ATPIF1 ATPase inhibitory factor 1 2.25945
EZR ezrin 2.23618
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 2.21797
RALBP1 ralA binding protein 1 2.2068
MTCH1 mitochondrial carrier 1 2.195
CYB5R1 cytochrome b5 reductase 1 2.18635
CLU clusterin 2.14895
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 2.14611
PPIA peptidylprolyl isomerase A (cyclophilin A) 2.13766
PSEN2 presenilin 2 2.13549
C6ORF89 chromosome 6 open reading frame 89 2.13422
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 2.10912
RASA3 RAS p21 protein activator 3 2.09756
CASP6 caspase 6, apoptosis-related cysteine peptidase 2.09733
PTPN2 protein tyrosine phosphatase, non-receptor type 2 2.09394
DERL1 derlin 1 2.07525
PTEN phosphatase and tensin homolog 2.07467
NFE2L2 nuclear factor, erythroid 2-like 2 2.07415
AP3D1 adaptor-related protein complex 3, delta 1 subunit 2.06846
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 2.05851
PDK1 pyruvate dehydrogenase kinase, isozyme 1 2.05442
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 2.03789
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 2.03614
ARF5 ADP-ribosylation factor 5 2.03366
SLA2 Src-like-adaptor 2 2.02775
AKIRIN2 akirin 2 2.0204
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 2.01502
HMP19 HMP19 protein 2.00061
REEP5 receptor accessory protein 5 1.99474
MCL1 myeloid cell leukemia 1 1.97411
FMN1 formin 1 1.96391
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 1.96225
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 1.96127
PPP4R2 protein phosphatase 4, regulatory subunit 2 1.95182
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 1.95128
CALU calumenin 1.94258
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 1.93309
PTGR1 prostaglandin reductase 1 1.93136
VAMP8 vesicle-associated membrane protein 8 1.92014
ATP13A1 ATPase type 13A1 1.91967
RRH retinal pigment epithelium-derived rhodopsin homolog 1.91782
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 1.90133
ANXA11 annexin A11 1.89993
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 1.88863
CDK8 cyclin-dependent kinase 8 1.88311
TEX30 testis expressed 30 1.88005
PCBP2 poly(rC) binding protein 2 1.87847
UXS1 UDP-glucuronate decarboxylase 1 1.86941
SUMO3 small ubiquitin-like modifier 3 1.86867
PLIN2 perilipin 2 1.86345
FAM103A1 family with sequence similarity 103, member A1 1.84127
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 1.8411
TPP1 tripeptidyl peptidase I 1.83967
FLII flightless I homolog (Drosophila) 1.83626
TADA2B transcriptional adaptor 2B 1.83332
STX5 syntaxin 5 1.82945
TNNT3 troponin T type 3 (skeletal, fast) 1.82899
RPS19 ribosomal protein S19 1.82859
LGALS1 lectin, galactoside-binding, soluble, 1 1.82269
KPNB1 karyopherin (importin) beta 1 1.82241
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 1.82225
EMP1 epithelial membrane protein 1 1.81598
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 1.81395
STOM stomatin 1.80911
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 1.80885
CLK1 CDC-like kinase 1 1.80767
RPN1 ribophorin I 1.80443
EHMT2 euchromatic histone-lysine N-methyltransferase 2 1.80187
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 1.80152
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 1.80039
ZFP36 ZFP36 ring finger protein 1.7975
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 1.79559
IKBIP IKBKB interacting protein 1.79018
TEX261 testis expressed 261 1.78992
HEXA hexosaminidase A (alpha polypeptide) 1.78042
TNRC6A trinucleotide repeat containing 6A 1.767
CAPNS1 calpain, small subunit 1 1.75941
CYTH3 cytohesin 3 1.7415
TMED7 transmembrane emp24 protein transport domain containing 7 1.74119
SF3B5 splicing factor 3b, subunit 5, 10kDa 1.73631
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.73415
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.72999
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 1.72166
PLD1 phospholipase D1, phosphatidylcholine-specific 1.7215
FLOT1 flotillin 1 1.71907
RIT1 Ras-like without CAAX 1 1.71418
IFT27 intraflagellar transport 27 1.71159
TMEM43 transmembrane protein 43 1.70659
UBE2D2 ubiquitin-conjugating enzyme E2D 2 1.70161
COL9A2 collagen, type IX, alpha 2 1.68652
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 1.68458
PTGES3 prostaglandin E synthase 3 (cytosolic) 1.68222
FGFR1 fibroblast growth factor receptor 1 1.67878
LY6E lymphocyte antigen 6 complex, locus E 1.6751
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 1.67489
CDC5L cell division cycle 5-like 1.66371
GTF2A1 general transcription factor IIA, 1, 19/37kDa 1.65954
GOLT1B golgi transport 1B 1.65754
PCNA proliferating cell nuclear antigen 1.65136
NPDC1 neural proliferation, differentiation and control, 1 1.64931
CLK4 CDC-like kinase 4 1.64879
COPZ1 coatomer protein complex, subunit zeta 1 1.6467
DUSP1 dual specificity phosphatase 1 1.64425
EGR2 early growth response 2 1.63869
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 1.63848
NFYA nuclear transcription factor Y, alpha 1.63741
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.63665
OR4E2 olfactory receptor, family 4, subfamily E, member 2 1.63622
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 1.63391
PDLIM4 PDZ and LIM domain 4 1.63372
RPS12 ribosomal protein S12 1.63334
RHOD ras homolog family member D 1.62685
HSPG2 heparan sulfate proteoglycan 2 1.62319
ACTR10 actin-related protein 10 homolog (S. cerevisiae) 1.61773
TMBIM1 transmembrane BAX inhibitor motif containing 1 1.61714
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 1.61571
INO80E INO80 complex subunit E 1.6117
PER1 period circadian clock 1 1.61076
ELMOD3 ELMO/CED-12 domain containing 3 1.60366
FLOT2 flotillin 2 1.59784
AP2M1 adaptor-related protein complex 2, mu 1 subunit 1.5975
PAQR7 progestin and adipoQ receptor family member VII 1.59512
LIN7C lin-7 homolog C (C. elegans) 1.59477
MFSD1 major facilitator superfamily domain containing 1 1.5943
PRKG2 protein kinase, cGMP-dependent, type II 1.59176
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 1.59085
GORASP2 golgi reassembly stacking protein 2, 55kDa 1.59008
ITCH itchy E3 ubiquitin protein ligase 1.58557
ACOT9 acyl-CoA thioesterase 9 1.58492
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 1.58247
SIDT2 SID1 transmembrane family, member 2 1.58217
CD2AP CD2-associated protein 1.57791
MRPL52 mitochondrial ribosomal protein L52 1.57747
CIC capicua transcriptional repressor 1.5773
RPN2 ribophorin II 1.57708
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 1.57487
BTG2 BTG family, member 2 1.57326
BTF3L4 basic transcription factor 3-like 4 1.57236
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 1.57181
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 1.57177
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 1.5695
MTIF2 mitochondrial translational initiation factor 2 1.56835
SCAF11 SR-related CTD-associated factor 11 1.56794
CPNE3 copine III 1.56695
MAX MYC associated factor X 1.557
CRLF3 cytokine receptor-like factor 3 1.55693
WDR78 WD repeat domain 78 1.55664
MBD4 methyl-CpG binding domain protein 4 1.55108
DDR1 discoidin domain receptor tyrosine kinase 1 1.55028
ITSN1 intersectin 1 (SH3 domain protein) 1.54994
TSC22D1 TSC22 domain family, member 1 1.54983
FAM134A family with sequence similarity 134, member A 1.54417
NUDCD2 NudC domain containing 2 1.541
KDM3B lysine (K)-specific demethylase 3B 1.54058
PROS1 protein S (alpha) 1.54045
GSK3A glycogen synthase kinase 3 alpha 1.53867
FJX1 four jointed box 1 (Drosophila) 1.53849
FAM76B family with sequence similarity 76, member B 1.53714
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 1.5337
CYB561 cytochrome b561 1.533
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa 1.52834
IREB2 iron-responsive element binding protein 2 1.52608
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 1.52431
CHD8 chromodomain helicase DNA binding protein 8 1.52317
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.5227
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 1.51987
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 1.51874
CCK cholecystokinin 1.51858
TRAF3 TNF receptor-associated factor 3 1.51793
SF3B1 splicing factor 3b, subunit 1, 155kDa 1.51436
ACTN4 actinin, alpha 4 1.51128
PHF23 PHD finger protein 23 1.51043
WBP5 WW domain binding protein 5 1.51036
PHKB phosphorylase kinase, beta 1.50587
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 1.50506
RERE arginine-glutamic acid dipeptide (RE) repeats 1.50501
CTSB cathepsin B 1.50279
DOHH deoxyhypusine hydroxylase/monooxygenase 1.50111
XBP1 X-box binding protein 1 1.50088
RNF103 ring finger protein 103 1.50061
STX4 syntaxin 4 1.50023
PPP1R15B protein phosphatase 1, regulatory subunit 15B 1.49866
STK11IP serine/threonine kinase 11 interacting protein 1.49481
ACTN2 actinin, alpha 2 1.49285
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 1.49142
KLHL1 kelch-like family member 1 1.49111
SDC4 syndecan 4 1.48397
RPL21 ribosomal protein L21 1.48321
RPL19 ribosomal protein L19 1.4788
E2F8 E2F transcription factor 8 1.47805
KLF6 Kruppel-like factor 6 1.47267
YIPF5 Yip1 domain family, member 5 1.47089
SEC23B Sec23 homolog B (S. cerevisiae) 1.47049
PRAF2 PRA1 domain family, member 2 1.46905
ELL elongation factor RNA polymerase II 1.46846
SRRT serrate, RNA effector molecule 1.4611
CELF2 CUGBP, Elav-like family member 2 1.45509
TMEM176B transmembrane protein 176B 1.45275
HNRNPM heterogeneous nuclear ribonucleoprotein M 1.45066
ARF6 ADP-ribosylation factor 6 1.44764
SPRY4 sprouty homolog 4 (Drosophila) 1.44713
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 1.44462
SSBP2 single-stranded DNA binding protein 2 1.44381
C1ORF158 chromosome 1 open reading frame 158 1.4416
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.44068
THOC7 THO complex 7 1.43929
SCAF8 SR-related CTD-associated factor 8 1.43804
IQCK IQ motif containing K 1.43612
ANXA6 annexin A6 1.43358
IST1 increased sodium tolerance 1 homolog (yeast) 1.4332
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.43258
LEMD2 LEM domain containing 2 1.43158
PGLS 6-phosphogluconolactonase 1.4307
TIMP1 TIMP metallopeptidase inhibitor 1 1.4263
AP2A2 adaptor-related protein complex 2, alpha 2 subunit 1.42462
CSTB cystatin B (stefin B) 1.42329
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 1.42091
RAB11FIP5 RAB11 family interacting protein 5 (class I) 1.42051
CTSV cathepsin V 1.42009
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 1.41964
CENPB centromere protein B, 80kDa 1.41924
RABGAP1L RAB GTPase activating protein 1-like 1.41893
TBRG1 transforming growth factor beta regulator 1 1.41808
CTBP2 C-terminal binding protein 2 1.41479
EVI5 ecotropic viral integration site 5 1.41433
AZIN1 antizyme inhibitor 1 1.41214
ADAM10 ADAM metallopeptidase domain 10 1.41176
PNRC2 proline-rich nuclear receptor coactivator 2 1.41014
SNAI2 snail family zinc finger 2 1.40621
SUSD4 sushi domain containing 4 1.40524
RAN RAN, member RAS oncogene family 1.40294
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2 1.40025
DES desmin 1.3975
SGPL1 sphingosine-1-phosphate lyase 1 1.39677
FRYL FRY-like 1.39671
CDK9 cyclin-dependent kinase 9 1.39058
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 1.39026
CORO1B coronin, actin binding protein, 1B 1.38876
ESYT1 extended synaptotagmin-like protein 1 1.38755
SAE1 SUMO1 activating enzyme subunit 1 1.38751
SRSF2 serine/arginine-rich splicing factor 2 1.38598
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 1.38254
MYOG myogenin (myogenic factor 4) 1.38018
WTAP Wilms tumor 1 associated protein 1.37992
PRKCSH protein kinase C substrate 80K-H 1.37601
MFAP5 microfibrillar associated protein 5 1.36841
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.36742
RAB8A RAB8A, member RAS oncogene family 1.3607
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 1.36019
TNPO2 transportin 2 1.36013
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) 1.35677
RTN3 reticulon 3 1.35471
BCL10 B-cell CLL/lymphoma 10 1.35312
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 1.35212
NUMB numb homolog (Drosophila) 1.35185
BIRC6 baculoviral IAP repeat containing 6 1.35113
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 1.34855
LIG1 ligase I, DNA, ATP-dependent 1.34634
SEPT7 septin 7 1.34573
SLC31A1 solute carrier family 31 (copper transporter), member 1 1.34567
REG3G regenerating islet-derived 3 gamma 1.34528
CANX calnexin 1.3452
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa 1.34504
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 1.34478
MAOA monoamine oxidase A 1.3446
RAB9A RAB9A, member RAS oncogene family 1.34438
SH3BGRL SH3 domain binding glutamate-rich protein like 1.34406
SLC30A5 solute carrier family 30 (zinc transporter), member 5 1.34162
DIO2 deiodinase, iodothyronine, type II 1.34059
FOXO3 forkhead box O3 1.33934
LLGL1 lethal giant larvae homolog 1 (Drosophila) 1.33883
MEF2C myocyte enhancer factor 2C 1.33395
ERRFI1 ERBB receptor feedback inhibitor 1 1.33264

decreased expression

Symbol Name Standardized Value
STAT5A signal transducer and activator of transcription 5A -3.66296
MRPS21 mitochondrial ribosomal protein S21 -3.19892
FKBP4 FK506 binding protein 4, 59kDa -3.13064
MRPS34 mitochondrial ribosomal protein S34 -3.02515
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -3.00977
MDH1 malate dehydrogenase 1, NAD (soluble) -2.98721
HIGD2A HIG1 hypoxia inducible domain family, member 2A -2.96184
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa -2.94786
TSC2 tuberous sclerosis 2 -2.91343
SYNGR1 synaptogyrin 1 -2.91331
SOAT2 sterol O-acyltransferase 2 -2.86817
MRPL38 mitochondrial ribosomal protein L38 -2.85499
PARL presenilin associated, rhomboid-like -2.84447
FGGY FGGY carbohydrate kinase domain containing -2.82516
CLCNKB chloride channel, voltage-sensitive Kb -2.81521
PFKM phosphofructokinase, muscle -2.79341
UQCRB ubiquinol-cytochrome c reductase binding protein -2.78025
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) -2.74982
PROSC proline synthetase co-transcribed homolog (bacterial) -2.72947
TMEM141 transmembrane protein 141 -2.72803
DGUOK deoxyguanosine kinase -2.72222
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 -2.67549
THUMPD1 THUMP domain containing 1 -2.65345
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -2.64894
OSBPL1A oxysterol binding protein-like 1A -2.64817
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 -2.63404
ZDHHC7 zinc finger, DHHC-type containing 7 -2.61873
ABHD16A abhydrolase domain containing 16A -2.58541
TMEM126A transmembrane protein 126A -2.58217
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -2.57941
ASNS asparagine synthetase (glutamine-hydrolyzing) -2.56664
MRPS18B mitochondrial ribosomal protein S18B -2.52926
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa -2.5196
UQCRC1 ubiquinol-cytochrome c reductase core protein I -2.50989
RANGRF RAN guanine nucleotide release factor -2.50424
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -2.50248
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.50241
ZCCHC6 zinc finger, CCHC domain containing 6 -2.4971
DQX1 DEAQ box RNA-dependent ATPase 1 -2.487
PPP1R12C protein phosphatase 1, regulatory subunit 12C -2.48099
MRPL39 mitochondrial ribosomal protein L39 -2.47517
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa -2.45243
FECH ferrochelatase -2.44502
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma -2.4387
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 -2.42954
FDXR ferredoxin reductase -2.42556
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -2.37659
MRPL4 mitochondrial ribosomal protein L4 -2.35814
DDA1 DET1 and DDB1 associated 1 -2.34701
MRPL18 mitochondrial ribosomal protein L18 -2.34318
ANAPC13 anaphase promoting complex subunit 13 -2.34127
HIST1H2BI histone cluster 1, H2bi -2.33906
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -2.32955
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -2.32857
ETFA electron-transfer-flavoprotein, alpha polypeptide -2.32523
GHRHR growth hormone releasing hormone receptor -2.31894
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.30044
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -2.29184
KRTAP13-2 keratin associated protein 13-2 -2.28274
MPG N-methylpurine-DNA glycosylase -2.27907
PEX11B peroxisomal biogenesis factor 11 beta -2.2655
GPX2 glutathione peroxidase 2 -2.24323
UBE2D3 ubiquitin-conjugating enzyme E2D 3 -2.24051
MRPL15 mitochondrial ribosomal protein L15 -2.23182
BAG2 BCL2-associated athanogene 2 -2.23182
ACYP2 acylphosphatase 2, muscle type -2.23018
MSL1 male-specific lethal 1 homolog (Drosophila) -2.22625
C6ORF136 chromosome 6 open reading frame 136 -2.22453
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide -2.2209
MED28 mediator complex subunit 28 -2.21985
RBM18 RNA binding motif protein 18 -2.21405
UNG uracil-DNA glycosylase -2.20983
BCL2L10 BCL2-like 10 (apoptosis facilitator) -2.20719
CHD1L chromodomain helicase DNA binding protein 1-like -2.20295
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 -2.20158
HDAC5 histone deacetylase 5 -2.19242
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10 -2.1618
TRIM11 tripartite motif containing 11 -2.15655
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 -2.15145
NLRX1 NLR family member X1 -2.14044
SULF2 sulfatase 2 -2.14041
RBBP4 retinoblastoma binding protein 4 -2.13432
SNX14 sorting nexin 14 -2.13249
GTF2A2 general transcription factor IIA, 2, 12kDa -2.11465
PSTK phosphoseryl-tRNA kinase -2.11448
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -2.09014
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -2.08676
ADPRH ADP-ribosylarginine hydrolase -2.08449
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 -2.08019
RAB24 RAB24, member RAS oncogene family -2.07161
ZFP36L2 ZFP36 ring finger protein-like 2 -2.06873
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.06789
MRPL17 mitochondrial ribosomal protein L17 -2.05586
PRDX3 peroxiredoxin 3 -2.05346
GTF2I general transcription factor IIi -2.0493
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) -2.04791
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -2.04221
AKAP8 A kinase (PRKA) anchor protein 8 -2.04131
HSBP1 heat shock factor binding protein 1 -2.031
IL6ST interleukin 6 signal transducer -2.02863
CSDE1 cold shock domain containing E1, RNA-binding -2.02309
TUBA4A tubulin, alpha 4a -2.02023
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa -2.01916
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 -2.00592
ASF1A anti-silencing function 1A histone chaperone -2.00441
SIRT2 sirtuin 2 -2.00069
SHFM1 split hand/foot malformation (ectrodactyly) type 1 -2.00026
HIAT1 hippocampus abundant transcript 1 -1.99922
SUCLG1 succinate-CoA ligase, alpha subunit -1.99746
APIP APAF1 interacting protein -1.99485
STIP1 stress-induced phosphoprotein 1 -1.99251
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit -1.98807
CISH cytokine inducible SH2-containing protein -1.98023
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma -1.97902
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -1.97595
SPNS1 spinster homolog 1 (Drosophila) -1.9757
TMEM185A transmembrane protein 185A -1.97181
CTF1 cardiotrophin 1 -1.96901
CUL7 cullin 7 -1.96669
FTO fat mass and obesity associated -1.95685
CLCN3 chloride channel, voltage-sensitive 3 -1.95175
NSUN4 NOP2/Sun domain family, member 4 -1.94706
SRSF3 serine/arginine-rich splicing factor 3 -1.94487
DAXX death-domain associated protein -1.9439
NME4 NME/NM23 nucleoside diphosphate kinase 4 -1.93628
MAPK12 mitogen-activated protein kinase 12 -1.93482
MDP1 magnesium-dependent phosphatase 1 -1.92484
ACOT7 acyl-CoA thioesterase 7 -1.92436
MRPL11 mitochondrial ribosomal protein L11 -1.92181
LUC7L3 LUC7-like 3 (S. cerevisiae) -1.91807
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -1.91765
BOLA3 bolA family member 3 -1.91579
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase -1.90823
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -1.90527
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase -1.89319
MEF2B myocyte enhancer factor 2B -1.89301
TMEM109 transmembrane protein 109 -1.88846
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -1.88549
FIBP fibroblast growth factor (acidic) intracellular binding protein -1.88433
SERTAD1 SERTA domain containing 1 -1.85912
ROR1 receptor tyrosine kinase-like orphan receptor 1 -1.85695
FNTA farnesyltransferase, CAAX box, alpha -1.85655
ZNF362 zinc finger protein 362 -1.85568
CINP cyclin-dependent kinase 2 interacting protein -1.85544
ETHE1 ethylmalonic encephalopathy 1 -1.85461
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -1.84917
CASP8AP2 caspase 8 associated protein 2 -1.84677
COQ9 coenzyme Q9 -1.84601
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit -1.84569
ELOF1 elongation factor 1 homolog (S. cerevisiae) -1.84423
RANBP10 RAN binding protein 10 -1.84364
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -1.84164
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -1.838
AP1S1 adaptor-related protein complex 1, sigma 1 subunit -1.83504
GDI2 GDP dissociation inhibitor 2 -1.82765
CAPN10 calpain 10 -1.82536
CDCA3 cell division cycle associated 3 -1.82465
GARS glycyl-tRNA synthetase -1.81897
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) -1.81856
MLEC malectin -1.81725
EMC2 ER membrane protein complex subunit 2 -1.81536
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) -1.81199
STX18 syntaxin 18 -1.81157
RNMTL1 RNA methyltransferase like 1 -1.80977
FXYD1 FXYD domain containing ion transport regulator 1 -1.80892
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -1.80836
AP2S1 adaptor-related protein complex 2, sigma 1 subunit -1.80779
GSTM3 glutathione S-transferase mu 3 (brain) -1.80698
NRD1 nardilysin (N-arginine dibasic convertase) -1.80682
GNG5 guanine nucleotide binding protein (G protein), gamma 5 -1.8057
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12 -1.80044
STMN4 stathmin-like 4 -1.79845
MRPL51 mitochondrial ribosomal protein L51 -1.79825
HDLBP high density lipoprotein binding protein -1.79592
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -1.7949
THOC3 THO complex 3 -1.7936
HAGH hydroxyacylglutathione hydrolase -1.79195
BANF1 barrier to autointegration factor 1 -1.79164
RUFY1 RUN and FYVE domain containing 1 -1.79124
BCAS2 breast carcinoma amplified sequence 2 -1.78963
IKZF4 IKAROS family zinc finger 4 (Eos) -1.78822
SERHL2 serine hydrolase-like 2 -1.78799
GSR glutathione reductase -1.78628
DYM dymeclin -1.78494
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 -1.78298
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5 -1.77707
CWC15 CWC15 spliceosome-associated protein -1.77504
EPX eosinophil peroxidase -1.77341
PRMT5 protein arginine methyltransferase 5 -1.77301
SERINC1 serine incorporator 1 -1.77189
PICK1 protein interacting with PRKCA 1 -1.76804
SHMT1 serine hydroxymethyltransferase 1 (soluble) -1.76193
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae) -1.7599
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 -1.75913
CD59 CD59 molecule, complement regulatory protein -1.75466
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -1.75375
EIF4A3 eukaryotic translation initiation factor 4A3 -1.75221
AXIN1 axin 1 -1.75101
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 -1.74873
MRPL37 mitochondrial ribosomal protein L37 -1.74374
PLA2G5 phospholipase A2, group V -1.74066
LIG3 ligase III, DNA, ATP-dependent -1.73756
BTF3 basic transcription factor 3 -1.73744
OTP orthopedia homeobox -1.72883
ACSL1 acyl-CoA synthetase long-chain family member 1 -1.72558
RPS24 ribosomal protein S24 -1.72549
SHKBP1 SH3KBP1 binding protein 1 -1.72176
SRPK3 SRSF protein kinase 3 -1.71857
ADK adenosine kinase -1.71623
SLC30A3 solute carrier family 30 (zinc transporter), member 3 -1.71437
CACNB2 calcium channel, voltage-dependent, beta 2 subunit -1.71389
SPAG7 sperm associated antigen 7 -1.71184
DMD dystrophin -1.70898
HMBS hydroxymethylbilane synthase -1.70742
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 -1.70587
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -1.7046
RAD51AP1 RAD51 associated protein 1 -1.70218
CUL1 cullin 1 -1.69469
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -1.69348
NUMA1 nuclear mitotic apparatus protein 1 -1.69296
GATA1 GATA binding protein 1 (globin transcription factor 1) -1.69165
AIP aryl hydrocarbon receptor interacting protein -1.69081
PUF60 poly-U binding splicing factor 60KDa -1.69011
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) -1.68774
RPS29 ribosomal protein S29 -1.68579
BLMH bleomycin hydrolase -1.68181
HMOX2 heme oxygenase 2 -1.67656
PRKD2 protein kinase D2 -1.6759
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1 -1.67466
MRPL2 mitochondrial ribosomal protein L2 -1.67418
COL9A3 collagen, type IX, alpha 3 -1.67229
DCTN3 dynactin 3 (p22) -1.67217
ZEB1 zinc finger E-box binding homeobox 1 -1.67085
TSFM Ts translation elongation factor, mitochondrial -1.67024
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -1.66956
KIF16B kinesin family member 16B -1.66704
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -1.66677
FABP3 fatty acid binding protein 3, muscle and heart -1.66532
ORC5 origin recognition complex, subunit 5 -1.66511
RNF166 ring finger protein 166 -1.66505
MCEE methylmalonyl CoA epimerase -1.66058
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -1.65966
TMEM30A transmembrane protein 30A -1.65823
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -1.65611
HINT1 histidine triad nucleotide binding protein 1 -1.65458
NME6 NME/NM23 nucleoside diphosphate kinase 6 -1.6541
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -1.65216
MRPS15 mitochondrial ribosomal protein S15 -1.64725
CTSK cathepsin K -1.64685
MTSS1L metastasis suppressor 1-like -1.64646
PGRMC2 progesterone receptor membrane component 2 -1.64605
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa -1.64396
SYTL4 synaptotagmin-like 4 -1.64152
ITFG1 integrin alpha FG-GAP repeat containing 1 -1.63975
RFK riboflavin kinase -1.638
ITPK1 inositol-tetrakisphosphate 1-kinase -1.63678
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -1.63576
LEFTY1 left-right determination factor 1 -1.63444
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -1.63382
HIST1H2BA histone cluster 1, H2ba -1.63248
MTX1 metaxin 1 -1.63089
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -1.63006
ELAVL1 ELAV like RNA binding protein 1 -1.62949
CHMP2A charged multivesicular body protein 2A -1.62835
LAPTM4B lysosomal protein transmembrane 4 beta -1.62731
RPS26 ribosomal protein S26 -1.62645
IPO7 importin 7 -1.62503
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 -1.62302
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit -1.61135
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) -1.61033
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -1.60989
LEP leptin -1.60807
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 -1.598
PRADC1 protease-associated domain containing 1 -1.5915
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 -1.59003
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 -1.58661
MYZAP myocardial zonula adherens protein -1.58441
UBE2Z ubiquitin-conjugating enzyme E2Z -1.58104
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) -1.57935
NOP10 NOP10 ribonucleoprotein -1.57862
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 -1.57628
IPO5 importin 5 -1.57067
SYK spleen tyrosine kinase -1.56704
RTN2 reticulon 2 -1.56361
CAB39L calcium binding protein 39-like -1.56105
PPAN peter pan homolog (Drosophila) -1.55653
LUC7L LUC7-like (S. cerevisiae) -1.55545
ITGB1BP1 integrin beta 1 binding protein 1 -1.55281
MED22 mediator complex subunit 22 -1.55253
MRPL54 mitochondrial ribosomal protein L54 -1.55207
MRPL36 mitochondrial ribosomal protein L36 -1.54729
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 -1.54707
TIMELESS timeless circadian clock -1.54427
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -1.54208
GOLGA3 golgin A3 -1.53605
REPIN1 replication initiator 1 -1.53119
INSL3 insulin-like 3 (Leydig cell) -1.52491
GPHN gephyrin -1.52403
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -1.52383
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -1.52273