Drug Eruptions Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

29 genes associated with the Drug Eruptions phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
CCHCR1 coiled-coil alpha-helical rod protein 1
CD28 CD28 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD86 CD86 molecule
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DPYD dihydropyrimidine dehydrogenase
EGFR epidermal growth factor receptor
ERCC2 excision repair cross-complementation group 2
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IL18 interleukin 18
IL1B interleukin 1, beta
KRAS Kirsten rat sarcoma viral oncogene homolog
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
TNF tumor necrosis factor
TYMS thymidylate synthetase
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1