Disease Progression Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D018450
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Genes

160 genes/proteins associated with the disease Disease Progression from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
ACAD8 acyl-CoA dehydrogenase family, member 8 2.88009
TMEM63A transmembrane protein 63A 2.88009
CAT catalase 2.88009
CCT7 chaperonin containing TCP1, subunit 7 (eta) 2.88009
SNX5 sorting nexin 5 2.88009
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 2.88009
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 2.88009
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 2.88009
TERT telomerase reverse transcriptase 2.88009
URM1 ubiquitin related modifier 1 2.88009
ZEB2 zinc finger E-box binding homeobox 2 2.88009
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 2.88009
DDB1 damage-specific DNA binding protein 1, 127kDa 2.88009
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 2.88009
EGFR epidermal growth factor receptor 2.88009
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 2.88009
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 2.88009
PPAP2A phosphatidic acid phosphatase type 2A 2.88009
PRPF19 pre-mRNA processing factor 19 2.88009
FGF2 fibroblast growth factor 2 (basic) 2.88009
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 2.88009
MIR200C microRNA 200c 2.88009
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 2.88009
PHB prohibitin 2.88009
RXRB retinoid X receptor, beta 2.88009
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 2.88009
CLCN3 chloride channel, voltage-sensitive 3 2.88009
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 2.88009
YY1 YY1 transcription factor 2.88009
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 2.88009
CCNE1 cyclin E1 2.88009
SREBF2 sterol regulatory element binding transcription factor 2 2.88009
ATF2 activating transcription factor 2 2.88009
KEAP1 kelch-like ECH-associated protein 1 2.88009
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 2.88009
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 2.88009
RPL18 ribosomal protein L18 2.88009
UBXN1 UBX domain protein 1 2.88009
SUCLG1 succinate-CoA ligase, alpha subunit 2.88009
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 2.88009
ESR1 estrogen receptor 1 2.88009
EGF epidermal growth factor 2.88009
SERBP1 SERPINE1 mRNA binding protein 1 2.88009
CHEK2 checkpoint kinase 2 2.88009
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.88009
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 2.88009
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 2.88009
C11ORF73 chromosome 11 open reading frame 73 2.88009
RPS6 ribosomal protein S6 2.88009
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 2.88009
FKBP2 FK506 binding protein 2, 13kDa 2.88009
RPL13 ribosomal protein L13 2.88009
RPL15 ribosomal protein L15 2.88009
TRAP1 TNF receptor-associated protein 1 2.88009
RAD23A RAD23 homolog A (S. cerevisiae) 2.88009
BOP1 block of proliferation 1 2.88009
PTOV1 prostate tumor overexpressed 1 2.88009
ERBB2 erb-b2 receptor tyrosine kinase 2 2.88009
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 2.88009
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 2.88009
PTEN phosphatase and tensin homolog 2.88009
FAM168A family with sequence similarity 168, member A 2.88009
RPS15 ribosomal protein S15 2.88009
RPS19 ribosomal protein S19 2.88009
PTPRF protein tyrosine phosphatase, receptor type, F 2.88009
MIR200B microRNA 200b 2.88009
PA2G4 proliferation-associated 2G4, 38kDa 2.88009
ING1 inhibitor of growth family, member 1 2.88009
STAT1 signal transducer and activator of transcription 1, 91kDa 2.88009
KDM1A lysine (K)-specific demethylase 1A 2.88009
SOD3 superoxide dismutase 3, extracellular 2.88009
RPS26 ribosomal protein S26 2.88009
RPS21 ribosomal protein S21 2.88009
NBAS neuroblastoma amplified sequence 2.88009
MRPS11 mitochondrial ribosomal protein S11 2.88009
ARG2 arginase 2 2.88009
CARKD carbohydrate kinase domain containing 2.88009
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa 2.88009
WDR46 WD repeat domain 46 2.88009
MRPS18B mitochondrial ribosomal protein S18B 2.88009
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 2.88009
PREP prolyl endopeptidase 2.88009
ABT1 activator of basal transcription 1 2.88009
COPS7A COP9 signalosome subunit 7A 2.88009
CSTA cystatin A (stefin A) 2.88009
SOD2 superoxide dismutase 2, mitochondrial 2.88009
RAP1GAP RAP1 GTPase activating protein 2.88009
ATP7B ATPase, Cu++ transporting, beta polypeptide 2.88009
BCL2 B-cell CLL/lymphoma 2 2.88009
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 2.88009
CTSB cathepsin B 2.88009
CTSC cathepsin C 2.88009
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) 2.88009
EPHA2 EPH receptor A2 2.88009
RRM1 ribonucleotide reductase M1 2.88009
HNRNPL heterogeneous nuclear ribonucleoprotein L 2.88009
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.88009
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 2.88009
KLK3 kallikrein-related peptidase 3 2.88009
ZNF593 zinc finger protein 593 2.88009
ZEB1 zinc finger E-box binding homeobox 1 2.88009
MRPL13 mitochondrial ribosomal protein L13 2.88009
CNPY2 canopy FGF signaling regulator 2 2.88009
TXNIP thioredoxin interacting protein 2.88009
EXOSC5 exosome component 5 2.88009
RANBP10 RAN binding protein 10 2.88009
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 2.88009
HRAS Harvey rat sarcoma viral oncogene homolog 2.88009
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 2.88009
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 2.88009
PUS1 pseudouridylate synthase 1 2.88009
CLN3 ceroid-lipofuscinosis, neuronal 3 2.88009
SYMPK symplekin 2.88009
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 2.88009
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 2.88009
NOP56 NOP56 ribonucleoprotein 2.88009
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4 2.88009
GSTP1 glutathione S-transferase pi 1 2.88009
PRDX3 peroxiredoxin 3 2.88009
CGA glycoprotein hormones, alpha polypeptide 2.88009
M6PR mannose-6-phosphate receptor (cation dependent) 2.88009
MMP2 matrix metallopeptidase 2 2.88009
PRDX4 peroxiredoxin 4 2.88009
CRP C-reactive protein, pentraxin-related 1.28919
MAPK14 mitogen-activated protein kinase 14 1.27162
BCL2L1 BCL2-like 1 1.26825
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.23456
SOD1 superoxide dismutase 1, soluble 1.18059
TGFB1 transforming growth factor, beta 1 1.17662
PLAT plasminogen activator, tissue 1.16833
MGMT O-6-methylguanine-DNA methyltransferase 1.15627
PCNA proliferating cell nuclear antigen 1.14336
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.13793
EGR1 early growth response 1 1.13177
FYN FYN proto-oncogene, Src family tyrosine kinase 1.12906
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.11606
PARP1 poly (ADP-ribose) polymerase 1 1.11081
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.11046
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.10977
ACTA2 actin, alpha 2, smooth muscle, aorta 1.10493
ZNF296 zinc finger protein 296 1.07732
ICAM1 intercellular adhesion molecule 1 1.07057
BAK1 BCL2-antagonist/killer 1 1.06625
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.06442
H2AFX H2A histone family, member X 1.06008
CYCS cytochrome c, somatic 1.05535
CLU clusterin 1.04794
GZMK granzyme K (granzyme 3; tryptase II) 1.04538
GPX4 glutathione peroxidase 4 1.04427
GCH1 GTP cyclohydrolase 1 1.03604
FAS Fas cell surface death receptor 1.03308
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.03009
RPSA ribosomal protein SA 1.02821
TP53 tumor protein p53 1.02596
CTSK cathepsin K 1.01739
SEC61G Sec61 gamma subunit 1.01663
NQO1 NAD(P)H dehydrogenase, quinone 1 1.01399
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 1.01399
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.01212
HSPB1 heat shock 27kDa protein 1 1.01062